List of publications:

Kumar, A., Basak, S., & Chakrapani, S.. Recombinant expression and purification of pentameric ligand-gated ion channels for Cryo-EM structural studies. In Ion Channels Part A (1st ed.). Elsevier Inc. Methods in Enzymology (2021)

Basak, S., Kumar, A., Ramsey, S., Gibbs, E., Kapoor, A., Filizola, M., & Chakrapani, S. (2020)., High-resolution Structures of multiple 5-HT3AR-setron complexes reveal a novel mechanism of competitive inhibition. eLife 2020

Kumar, A., Basak, S., Rao, S., Gicheru, Y., Mayer, M.L., M S.P Sansom., and Chakrapani,S . Mechanisms of activation and desensitization of full-length glycine receptor in lipid nanodiscs. Nature communication. 2020

Basak, S.*, Gicheru, Y.*, Kapoor, A., Mayer, M.L, Filizola, M., and Chakrapani,S Molecular mechanism of setron-mediated inhibition of full-length 5-HT3A receptor. Nature communication. 2019

Basak, S., Gicheru, Y., S Rao, M S.P Sansom, and Chakrapani,S . Cryo-EM reveals two distinct serotonin-bound conformations of full-length 5-HT _3A receptor. Nature volume 563, pages 270–274 (2018)

Basak, S., Gicheru, Y., Samanta, A., Molugu, S., Huang, W., Fuente, M. D. L., Hughes, T., Taylor, D., Nieman, M., Moiseenkova-Bell, V.Y. & Chakrapani,S. (2018) Cryo-EM structure of 5-HT3A receptor in its resting conformation. Nature communication. 9, 514.

Hughes TET, Lodowski DT, Huynh KW, Yazici A, Del Rosario J, Kapoor A, Basak S, Samanta A, Han X, Chakrapani S, Zhou ZH, Filizola M, Rohacs T, Han S, & Moiseenkova-Bell VY. Structural basis of TRPV5 channel inhibition by econazole revealed by cryo-EM. (2018) Nat Struct Mol Biol. Jan;25(1):53-60

Basak, S.*, Schmandt, N.*, Gicheru, Y.*, & Chakrapani, S. (2017). Crystal structure and dynamics of a lipid-induced potential desensitized-state of a pentameric ligand-gated channel. eLife, 6.

Basak, S., Chatterjee, S., & Chakrapani, S. (2016). Site directed spin labeling and EPR spectroscopic studies of pentameric ligand-gated ion channels. Journal of Visualized Experiments, 2016(113).

Nartey, W., Basak, S., Kamariah, N., Manimekalai, M. S. S., Robson, S., Wagner, G., Eisenhaber, B., Eisenhaber, F. & Grüber, G. (2015). NMR studies reveal a novel grab and release mechanism for efficient catalysis of the bacterial 2-Cys peroxiredoxin machinery. FEBS Journal, 282(23), 4620–4638.

Balakrishna, A. M.*, Basak, S.*, Manimekalai, M. S. S., & Grüber, G. (2015). Crystal structure of subunits D and F in complex gives insight into energy transmission of the eukaryotic V-ATPase from Saccharomyces cerevisiae. Journal of Biological Chemistry, 290(6), 3183–3196.

Basak, S., Lim, J., Manimekalai, M. S. S., Balakrishna, A. M., & Grüber, G. (2013). Crystal and NMR structures give insights into the role and dynamics of Subunit F of the eukaryotic V-ATPase from Saccharomyces cerevisiae. Journal of Biological Chemistry, 288(17), 11930–11939.

Biuković, G., Basak, S., Manimekalai, M. S. S., Rishikesan, S., Roessle, M., Dick, T., … Grüber, G. (2013). Variations of subunit ε of the Mycobacterium tuberculosis F 1FO ATP synthase and a novel model for mechanism of action of the tuberculosis drug TMC207. Antimicrobial Agents and Chemotherapy, 57(1), 168–176.

Pattnaik, G., Sinha, B., Mukherjee, B., Ghosh, S., Basak, S., Mondal, S., & Bera, T. (2012). Submicron-size biodegradable polymer-based didanosine particles for treating HIV at early stage: An in vitro study. Journal of Microencapsulation, 29(7), 666–676.

Basak, S., Balakrishna, A. M., Manimekalai, M. S. S., & Grüber, G. (2012). Crystallization and preliminary X-ray crystallographic analysis of subunit F (F1-94), an essential coupling subunit of the eukaryotic V 1Vo-ATPase from Saccharomyces cerevisiae. Acta Crystallographica Section F: Structural Biology and Crystallization Communications, 68(9), 1055–1059.

Basak, S., Gayen, S., Ramalingam, J. K., Grüber, A., Preiser, P. R., & Grüber, G. (2011). NMR solution structure of NBD94483-502 of the nucleotide-binding domain of the Plasmodium yoelii reticulocyte-binding protein Py235. FEMS Microbiology Letters, 318(2), 152–158.

Basak, S., Gayen, S., Thaker, Y. R., Manimekalai, M. S. S., Roessle, M., Hunke, C., & Grüber, G. (2011). Solution structure of subunit F (Vma7p) of the eukaryotic V 1VO ATPase from Saccharomyces cerevisiae derived from SAXS and NMR spectroscopy. Biochimica et Biophysica Acta - Biomembranes, 1808(1), 360–368.

* denotes equal contribution.