Agenda

Friday July 19th, 2019

Registration and Continental Breakfast 8:00 - 8:45 AM

Linsalata Alumni Center, Foyer

Session 1

Outlining the Challenges to Treatment and Recovery for Opioid Use Disorder

Linsalata Alumni Center, Foster-Castele Great Hall

Chair: Stephen Lewis, Case Western Reserve University

8:45 Robert J. Ronis, MD, MPH Co-Director of the Center for Evidence-Based Practices at Case Western Reserve University & the Douglas Danford Bond Professor and Chairman of the Department of Psychiatry at Case Western Reserve University School of Medicine/University Hospitals Cleveland Medical Center

Introductory remarks

8:55 Lee Hoffer, PhD, MPE Associate Professor of Medical Anthropology and Psychiatry, Case Western Reserve University

Title: "Assessing recent trends in opioid use among people who inject drugs: Findings from a NDEWS HotSpot study of Cuyahoga County"

9:25 Jeanne Lackamp, MD Associate Professor of Psychiatry, Director, Division of Psychiatry and Medicine, Director, University Hospitals Pain Management Institute.

Title: “The Opioid Crisis and Pain Management: University Hospitals System Response"

9:55 Annie Fahy, LCSW, RN Substance Use Disorders and Harm Reduction Specialist, Founder and CEO of Annie Fahy Consulting

Supported by the Courtney Burton Frontiers in Medicine Lectureship

Title: “The Conversation is the Medicine: Using Motivational Interviewing to enhance and strengthen personal motivation for behavior change”

10:25 Discussion

Coffee Break 10:45 - 11:00 AM

Session 2

Federal and Ohio Interventions into the Opioid Epidemic

Linsalata Alumni Center, Foster-Castele Great Hall

Chair: Robert Ronis, Case Western Reserve University

11:00 Wilson M Compton, MD, MPE Deputy Director of the National Institute on Drug Abuse (NIDA) of the National Institutes of Health (NIH)

Title: “U.S. Opioid Crisis: Science = Solutions”

Presenting via Zoom

11:45 Stephen Lewis, PhD Professor, Departments of Pediatrics and Pharmacology, School of Medicine, Case Western Reserve University, Functional Electrical Stimulation Center, Case Western Reserve University

Title: “Novel Thioester Compounds for Reversal of Opioid-Induced Respiratory Depression and Addiction”

12:15 Michael W. Konstan, MD Gertrude Lee Chandler Tucker Professor of Pediatrics and Professor of Population and Quantitative Health Sciences; Vice Dean for Translational Research, PI, Clinical and Translational Science Collaborative (CTSC) of Cleveland, Case Western Reserve University School of Medicine

Title: “HEALing Ohio and other Opioid Initiatives from the Clinical and Translational Science Collaborative of Cleveland (CTSC)”

12:30 Siran Koroukian, PhD Associate Professor of Population and Quantative Health Sciences, Director, Population Cancer Analytics Shared Resource Case Comprehensive Cancer Center, Case Western Reserve University School of Medicine

Title: "The Opioid Epidemic on a Course of Collision with Infectious Disease Epidemic and Associated Cancers"

Presenting via Zoom

12:45 Discussion

Lunch 1:00 - 2:00 PM

Linsalata Alumni Center, Foyer and Courtyard

Concurrent Sessions 3A and 3B

Session 3A: Novel Insights into the Mechanisms of Action of Opioids – 1

Linsalata Alumni Center, Foster-Castele Great Hall

Chair: Michael Jenkins, Case Western Reserve University

2:00 Ben Gaston, MD Vice Chair for Translational Research at the Herman B. Wells Center for Pediatric Research, Indiana University

Title: “The problem of OIRD in pediatric patients requiring critical care or affected with lung disease”

2:20 Hubert Forster, PhD Professor of Physiology, Medical College of Wisconsin

Title: “Brainstem site dependence of µ-opioid receptor (MOR) agonists effects on physiologic functions and neurochemical compensation”

2:35 Matthew Hodges, PhD Associate Professor of Physiology, Medical College of Wisconsin

Title: “Effects of systemic fentanyl on breathing control, pulmonary gas exchange and respiratory muscle activity in freely-behaving goats”

2:50 Yolanda Fortenberry, PhD Associate Professor of Biochemistry and Molecular Biology, Case Western Reserve University

Title: “Aptamers: The key to unlocking the mysterious effects of opioids in the body”

3:10 Pete MacFarlane, PhD Associate Professor of Pediatrics, Case Western Reserve University School of Medicine

Title: “Modulation of breathing by microglia during vulnerable windows of development – implications for neonatal opioid withdrawal syndrome”

3:30 Discussion

Session 3B: Progressive Responses to Opioid Use Disorder

Linsalata Alumni Center, Living Room

Chair: Ravenel Richardson, Case Western Reserve University

2:00 Simon Taxel, NRP, BA Crew Chief, City of Pittsburgh Bureau of EMS; medical specialist on the Pennsylvania Urban Search and Rescue Strike Team

Title: “The Opioid Crisis: A Paramedics Perspective”

2:30 Allison Schlosser, PhD Postdoctoral Fellow, Case Western Reserve University School of Medicine

Title: “Navigating the Paradoxes of Recovery in Ohio’s Opioid Epidemic

3:00 Daniel J. Flannery, PhD Semi J. and Ruth W. Begun Professor and Director, Begun Center for Violence Prevention Research and Education, Jack, Joseph and Morton Mandel School of Applied Social Sciences, Case Western Reserve University

Title: "Collaborating with law enforcement and the US Attorney's Task Force to address the heroin-opiate overdose crisis"

3:30 Discussion

Coffee Break 3:45 - 4:00 PM

Concurrent sessions 4A and 4B

Session 4A: Novel Insights into the Mechanisms of Action of Opioids – 2

Linsalata Alumni Center, Foster-Castele Great Hall

Chair: Ben Gaston, Herman B. Wells Center for Pediatric Research

4:00 Robert Kirsch, PhD Executive Director Cleveland FES Center; Chair and Professor of Biomedical Engineering, Case Western Reserve University

Title: “Current and future research activities of the FES Center relevant to the opioid crisis”

4:10 Michael Jenkins, PhD Assistant Research Professor of Biomedical Engineering, Case Western Reserve University

Title: “Potential new optical technologies for combating the opioid crisis”

4:30 Jason Bubier, PhD Jackson Labs, Bar Harbor Maine, Behavioral and Cognitive Impairment, Genetics and Genomics, Bioinformatics

Title: “Genetic variation in opioid induced respiratory depression in mice”

4:50 Devin Mueller, PhD Associate Professor of Biological Sciences, Kent State University

Title: “Neurotrophic mechanisms underlying prefrontal regulation of drug seeking after extinction”

5:10 James Seckler, PhD Research Associate, Department of Pediatrics, School of Medicine, Case Western Reserve University

Title: “Exploring the molecular mechanisms of action for D-cysteine ethyl ester: relevance to reversing OIRD”

5:30 Discussion

Session 4B: Integrated Approaches for the Treatment and Recovery of Mothers and Children

Linsalata Alumni Center, Living Room

Chair: Kathleen Clegg, University Hospitals Medical Center Cleveland

4:00 University Hospitals Cleveland Medical Center MOMS+ Team

Moira Crowley, MD Associate Professor, Pediatrics, Case Western Reserve University School of Medicine; Medical Co-Director, Neonatal Intensive Care Unit, Director, Neonatal ECMO Program, and Director, Neonatal Consultative Services, UH Rainbow Babies & Children’s Hospital

Lulu Zhao, MD Assistant Professor of Ob/Gyn, Behavioral Ob/Gyn, University Hospitals Cleveland Medical Center

Ann Kessler, LISW-S Senior Social Worker for the Department of Social Work, UH Rainbow Babies and Children’s Hospital, and Associate Director, UH Rainbow Babies and Children’s Center for Pediatric Ethics

Title: "MOMS+: Collaborative Approaches to Perinatal Addiction"

4:30 Project CARA Team

Melinda Ramage, BSN, MSN, FNP-BC Family Nurse Practitioner and Clinical Addiction Specialist for Project CARA: Care that Advocates Respect/Resilience/Recovery for All, Mountain Area Health Education Center (MAHEC), Asheville, North Carolina

Marie Gannon, LPC, LCAS, CCS Behavioral Health Director and Co-Founder, Project CARA at MAHEC;

Tamara Cody, LCSW Perinatal Substance Abuse Advisor, Project CARA, MAHEC

Title: “Project CARA: Community Collaboration to Serve the Needs of Pregnant Women Affected by Substance Use Disorders”

5:00 Warren County START Program Team

Shawna Barger, LISW-S Sobriety, Treatment, and Reducing Trauma (START) Program Administrator, Warren County, OH

Kirsten Stover START Program Supervisor

Michaela Parker START Program Caseworker

Sarah Neff START Program Family Peer Mentor

Title: “Warren County Sobriety, Treatment, and Reducing Trauma (START) Program: Hope STARTS Here”

5:30 Discussion

Reception 6:00 -7:30 PM

Linsalata Alumni Center, Foyer, Courtyard and Foster-Castele Great Hall

Saturday July 20th, 2019

Invited Speakers Only

Continental Breakfast 8:00 - 8:30 AM

Linsalata Alumni Center, Library

Session 1

Innovative Approaches to Treatment and Recovery in Cleveland

Linsalata Alumni Center, Living Room

Chair: Lee Hoffer, Case Western Reserve University

8:30 Christina Delos Reyes, MD Associate Professor of Psychiatry, Case Western Reserve University School of Medicine, Director, Addiction Psychiatry Fellowship and Addiction Services, University Hospitals Cleveland Medical Center

Title: “Treating the Opioid Epidemic – Clinical and Community Perspectives”

8:50 Maureen Fluoriano, MPH, MA Project DAWN Program Assistant, Office of Opioid Safety at MetroHealth Medical Center; Doctoral Candidate, Department of Anthropology, Case Western Reserve University College of Arts and Sciences

Title: "Naloxone as a Harm Reduction Tool in Response to the Opioid Crisis"

9:20 Corrilynn Hileman, MD, MS Medical Director Infectious Diseases Clinic, MetroHealth Medical Center; Assistant Professor of Medicine Case Western Reserve University School of Medicine

Title: "The Impact of Intravenous Heroin and Medication Assisted Treatment on Immune Activation in Treated HIV"

9:40 Basanta Mohapatra, MD Assistant Professor of Anesthesiology, Case Western Reserve University School of Medicine; Cardiac Anesthesiologist & Critical Care Intensivist, University Hospitals Cleveland Medical Center

Title: "Block the Pain, Block the Opioids"

10:00 Discussion

Coffee Break 10:15 -10:30 AM

Session 2

Integrating Scientific, Medical, and Social Approaches to Substance Abuse Disorder

Linsalata Alumni Center, Living Room

Chair: Stephen Lewis, Case Western Reserve University

10:30 AM -12:30 PM Roundtable Discussion