Athanason AC§, Nadav T, Cates-Gatto C, Roberts AJ, Roberto M, Varodayan FP. (2023). Chronic ethanol alters adrenergic receptor gene expression and produces cognitive deficits in male mice. Neurobiology of Stress, 27;24:100542. https://doi.org/10.1016/j.ynstr.2023.100542

Varodayan FP, Pahng AR, Davis TD, Gandhi P, Bajo M, Steinman MQ, Kiosses WB, Blednov YA, Burkart MD, Edwards S, Roberts AJ, Roberto M. (2023). Chronic ethanol induces a pro-inflammatory switch in interleukin-1β regulation of GABAergic signaling in the medial prefrontal cortex of male mice. Brain Behavior and Immunity, 110:125-139. https://doi.org/10.1016/j.bbi.2023.02.020

Gravielle MC, Pignataro L, Varodayan FP. (2023). Editorial: Plasticity of inhibitory cells in health and disease. Frontiers in Synaptic Neuroscience, 14:1127609. https://doi.org/10.3389/fnsyn.2022.1127609

Flores-Ramirez FJ, Varodayan FP, Patel RR, Illenberger JM, Di Ottavio F, Roberto M, Martin-Fardon R. (2022). Blockade of orexin receptors in the infralimbic cortex prevents stress-induced reinstatement of alcohol-seeking behavior in alcohol dependent rats. British Journal of Pharmacology, 180(11):1500-1515.  https://doi.org/10.1111/bph.16015

Rodriguez L, Kirson D, Wolfe SA, Patel RR, Varodayan FP, Snyder AE, Gandhi PJ, Khom S, Vlkolinsky R, Bajo M, Roberto M. (2022). Alcohol Dependence Induces CRF Sensitivity in Female Central Amygdala GABA Synapses. International Journal of Molecular Sciences, 23(14):7842. https://doi.org/10.3390/ijms23147842.

Varodayan FP, Patel RR, Matzeu A, Wolfe SA, Curley DE, Khom S, Gandhi PJ, Rodriguez L, Bajo M, D'Ambrosio S, Sun H, Kerr TM, Gonzales RA, Leggio L, Natividad LA, Haass-Koffler CL, Martin-Fardon R, Roberto M. (2022). The Amygdala Noradrenergic System Is Compromised With Alcohol Use Disorder. Biological Psychiatry, 91(12):1008-1018. https://doi.org/10.1016/j.biopsych.2022.02.006.

Patel RR*, Varodayan FP*, Herman MA, Jimenez V, Agnore R, Gao L, Bajo M, Cuzon Carlson VC, Walter NA, Fei SS, Grant KA, Roberto M. (2022). Synaptic effects of IL-1β and CRF in the central amygdala after protracted alcohol abstinence in male rhesus macaques. Neuropsychopharmacology, 47(4):847-856. https://doi.org/10.1038/s41386-021-01231-y. *Co-first authors

Kisby BR, Farris SP, McManus MM, Varodayan FP, Roberto M, Harris RA, Ponomarev I. (2021). Alcohol Dependence in Rats Is Associated with Global Changes in Gene Expression in the Central Amygdala. Brain Sciences, 11(9):1149. https://doi.org/10.3390/brainsci11091149.

Kirson D, Khom S, Rodriguez L, Wolfe SA, Varodayan FP, Gandhi PJ, Patel RR, Vlkolinsky R, Bajo M, Roberto M. (2021). Sex Differences in Acute Alcohol Sensitivity of Naïve and Alcohol Dependent Central Amygdala GABA Synapses. Alcohol Alcohol, 56(5):581-588. https://doi.org/10.1093/alcalc/agab034.

Farokhnia M, Berger AL, Karoly HC, Hwa LS, Varodayan FP. (2020). The Promise of Neuroimmune Targets for Treating Drug Addiction and Other Psychiatric Disorders: Granulocyte-Colony Stimulating Factor Exemplification. Frontiers in Psychiatry, 11:220. https://doi.org/10.3389/fpsyt.2020.00220.

Warden AS*, Wolfe SA*, Khom S*, Varodayan FP*, Patel RR, Steinman MQ, Bajo M, Montgomery SE, Vlkolinsky R, Nadav T, Polis I, Roberts AJ, Mayfield RD, Harris RA, Roberto M. (2020). Microglia Control Escalation of Drinking in Alcohol-Dependent Mice: Genomic and Synaptic Drivers. Biological Psychiatry, 88(12):910-921.  https://doi.org/10.1016/j.biopsych.2020.05.011. *Co-first authors

Khom S, Wolfe SA, Patel RR, Kirson D, Hedges DM, Varodayan FP, Bajo M, Roberto M. (2020). Alcohol Dependence and Withdrawal Impair Serotonergic Regulation of GABA Transmission in the Rat Central Nucleus of the Amygdala. Journal of Neuroscience, 40(36):6842-6853. https://doi.org/10.1523/JNEUROSCI.0733-20.2020.

Varodayan FP, Minning MA, Steinman MQ, Oleata CS, Riley MW, Sabino V, Roberto M. (2020). PACAP regulation of central amygdala GABAergic synapses is altered by restraint stress. Neuropharmacology, 168:107752. https://doi.org/10.1016/j.neuropharm.2019.107752.

Suárez J, Khom S, Alén F, Natividad LA, Varodayan FP, Patel RR, Kirson D, Arco R, Ballesta A, Bajo M, Rubio L, Martín-Fardon R, Rodríguez de Fonseca F, Roberto M. (2020). Cessation of fluoxetine treatment increases alcohol seeking during relapse and dysregulates endocannabinoid and glutamatergic signaling in the central amygdala. Addiction Biology, 25(5):e12813. https://doi.org/10.1111/adb.12813.

Bajo M, Patel RR, Hedges DM, Varodayan FP, Vlkolinsky R, Davis TD, Burkart MD, Blednov Y, Roberto M. (2019). Role of MyD88 in IL-1b and ethanol modulation of GABAergic transmission in the central amygdala. Brain Sciences, 9(12):361. https://doi.org/10.3390/brainsci9120361.

Patel RR, Khom S, Steinman MQ, Varodayan FP, Kiosses WB, Hedges D, Vlkolinsky R, Nadav T, Polis I, Bajo M, Roberts AJ, Roberto M. (2019). IL-1β expression is increased and regulates GABA transmission following chronic ethanol in mouse central amygdala. Brain, Behavior and Immunity, 75, 208-219. https://doi.org/10.1016/j.bbi.2018.10.009.  

Varodayan FP*, Sidhu H*, Roberto M, Contet C. (2018). Morphological and functional changes in prelimbic cortex dendritic spines induced by alcohol dependence. Neuropharmacology, 133, 470-480. https://doi.org/10.1016/j.neuropharm.2018.02.014. *Co-first authors

 Varodayan FP, Khom S, Patel RR, Hedges D, Steinman MQ, Oleata CS, George O, Roberto M, Bajo M. (2018). Role of TLR4 in the Modulation of Central Amygdala GABA Transmission by CRF Following Restraint Stress. Alcohol and Alcoholism, 53, 642-649. https://doi.org/10.1093/alcalc/agx114.

Blasio A, Wang J, Wang D, Varodayan FP, Pomrenze MB, Miller J, Lee AM, McMahon T, Gyawali S, Wang H, Roberto M, McHardy S, Pleiss MA, Messing RO. (2018). Novel Small Molecule Inhibitors of Protein Kinase C Epsilon Reduce Ethanol Consumption in Mice. Biological Psychiatry, 84, 193-201. https://doi.org/10.1016/j.biopsych.2017.10.017. 

Varodayan FP*, Correia D*, Kirson D*, Khom S, Oleata CS, Schweitzer P, Roberto M. (2017). CRF modulates glutamate transmission in the central amygdala of naïve and ethanol-dependent rats. Neuropharmacology, 125, 418-428. https://doi.org/10.1016/j.neuropharm.2017.08.009. *Co-first authors

 Varodayan FP, Logrip ML, Roberto M. (2017). P/Q-type voltage-gated calcium channels mediate the alcohol and CRF sensitivity of central amygdala GABAergic synapses. Neuropharmacology, 125, 97-206. https://doi.org/10.1016/j.neuropharm.2017.07.017.

Varodayan FP*, de Guglielmo G, Logrip ML, George O, Roberto M*. (2017). Alcohol dependence disrupts amygdalar L-type voltage-gated calcium channel mechanisms. Journal of Neuroscience, 37(17), 4593-4603. https://doi.org/10.1523/JNEUROSCI.3721-16.2017. *Co-corresponding authors  

Harris RA, Bajo M, Bell RL, Blednov YA, Varodayan FP, Truitt JM, de Guglielmo G, Lasek AW, Logrip ML, Vendruscolo LF, Roberts AJ, Roberts E, George O, Mayfield J, Billiar TR, Hackam DJ, Mayfield RD, Koob GF, Roberto M, Homanics GE. (2017). Genetic and Pharmacologic Manipulation of TLR4 Has Minimal Impact on Ethanol Consumption in Rodents. Journal of Neuroscience 37(5), 1139-1155. https://doi.org/10.1523/JNEUROSCI.2002-16.2016.

Varodayan FP, Bajo M, Soni N, Luu G, Madamba SG, Schweitzer P, Roberto M. (2017). Chronic alcohol exposure disrupts CB1 regulation of GABAergic transmission in the rat basolateral amygdala. Addiction Biology 22(3), 766-778. https://doi.org/10.1111/adb.12369.

Roberto M, Varodayan FP. (2017). Synaptic targets: Chronic alcohol actions. Neuropharmacology, 122, 85-99. https://doi.org/10.1016/j.neuropharm.2017.01.013.

Schweitzer P, Cates-Gatto C, Varodayan FP, Nadav T, Roberto M, Lasek AW, Roberts AJ. (2016). Dependence-induced ethanol drinking and GABA neurotransmission are altered in Alk deficient mice. Neuropharmacology 107, 1-8. https://doi.org/10.1016/j.neuropharm.2016.03.003.

 Varodayan FP, Soni N, Bajo M, Luu G, Madamba SG, Schweitzer P, Parsons LH, Roberto M. (2016). Chronic ethanol exposure decreases CB1 receptor function at GABAergic synapses in the rat central amygdala. Addiction Biology 21(4), 788-801. https://doi.org/10.1111/adb.12256.

 Herman MA, Varodayan FP, Oleata CS, Luu G, Kirson D, Heilig M, Ciccocioppo R, Robert M. (2016). Glutamatergic transmission in the central nucleus of the amygdala is selectively altered in Marchigian Sardinian alcohol-preferring rats: Alcohol and CRF effects. Neuropharmacology 102, 21-31. https://doi.org/10.1016/j.neuropharm.2015.10.027.

Bajo M, Varodayan FP, Madamba SG, Roberts AJ, Casal LM, Oleata C, Siggins GR, Roberto M. (2015). Interleukin-1 Interacts with Ethanol Effects on GABAergic Transmission in the Mouse Central Amygdala. Frontiers in Pharmacology 19(6), 49. https://doi.org/10.3389/fphar.2015.00049.

 Bajo M, Herman MA, Varodayan FP, Oleata CS, Madamba SG, Harris RA, Blednov YA, Roberto M. (2015). Role of the IL-1 receptor antagonist in ethanol-induced regulation of GABAergic transmission in the central amygdala. Brain, Behavior and Immunity 45, 189-97. https://doi.org/10.1016/j.bbi.2014.11.011.

Roberto M, Varodayan F. (2015). Commentary on the Third International Congress on “Alcoholism and Stress: A Framework for Future Treatment Strategies”. Alcohol 49(8), e1-2. https://doi.org/10.1016/j.alcohol.2015.11.007.

Kallupi M, Varodayan FP, Oleata CS, Correia D, Luu G, Roberto M. (2014). Nociceptin/Orphanin FQ decreases glutamate transmission and blocks ethanol-induced effects in the central amygdala of naïve and ethanol-dependent rats. Neuropsychopharmacology s39(5), 1081-92. https://doi.org/10.1038/npp.2013.308.

Varodayan FP*, Harrison NL. (2013). HSF1 transcriptional activity mediates alcohol induction of Vamp2 expression and GABA release. Frontiers in Integrative Neuroscience 7, 89.  https://doi.org/10.3389/fnint.2013.00089. *Corresponding author

Pignataro L*, Varodayan FP*, Tannenholz LE, Protiva P, Harrison NL. (2013). Brief alcohol exposure alters transcription in astrocytes via the heat shock pathway. Brain and Behavior 3(2), 114-133. https://doi.org/10.1002/brb3.125. *Co-first authors 

Varodayan FP, Pignataro L, Harrison NL. (2011). Alcohol induces Synaptotagmin 1 expression in neurons via activation of heat shock factor 1. Neuroscience 193, 63-71. https://doi.org/10.1016/j.neuroscience.2011.07.035.

Pignataro L, Varodayan FP, Tannenholz LE, Harrison NL. (2009). The regulation of neuronal gene expression by alcohol. Pharmacology and Therapeutics 124(3), 324-335. https://doi.org/10.1016/j.pharmthera.2009.09.002.

Varodayan FP, Zhu X, Cui X, Porter BE. (2009). Seizures increase cell proliferation in the dentate gyrus by shortening progenitor cell-cycle length. Epilepsia 50(12), 2638-2647. https://doi.org/10.1111/j.1528-1167.2009.02244.x. 

Porter BE, Lund IV, Varodayan FP, Wallace RW, Blendy JA. (2008). The role of transcription factors cyclic-AMP responsive element modulator (CREM) and inducible cyclic-AMP early repressor (ICER) in epileptogenesis. Neuroscience 152(3), 829-836. https://doi.org/10.1016/j.neuroscience.2007.10.064.

 Macgowan CK, Al-Kwifi O, Varodayan F, Yoo S, Wright GA, Kellenberger CJ. (2005). Optimization of 3D contrast-enhanced pulmonary magnetic resonance angiography in pediatric patients with congenital heart disease.  Magnetic Resonance in Medicine 54(1), 207-212. https://doi.org/10.1002/mrm.20538.