Leading up to the Chinese Exclusion Act in 1882 (and for many years after), there was a plethora of propaganda painting Chinese people as dirty and uncivilized carriers of disease—including tuberculosis. While it was true that overcrowded conditions in San Francisco's Chinatown led to generally high rates and spread of disease, a large factor in that was the Chinese peoples' mistrust of American health officials and lack of medical care facilities in Chinatown. Racist propaganda against Chinese people was further exacerbated by the fear many Americans had that the Chinese laborers would replace them, and zeroing in on their public health habits allowed Americans to push for the passage of the Chinese Exclusion Act.
Even now in more modern times, tuberculosis is still prevalent in Asians in California. In 2021, 49% out of all of California's tuberculosis cases were from Asians, even though they make up only 16% of California's total population. From 1993-2006, California was the state with the highest number of Asian or Pacific Islander cases of tuberculosis with 19,843 cases (40.70%). The second state was New York by a wide margin, with nearly a fourth of California's number of cases at 5,548 cases (11.40%).