Papers

Tripathi D, Rajnikanth PS, Pandey P. Electrospun Chitosan-Based Nanofibers for Wound Healing: Advances in Fabrication Strategies, Functionalization, and Clinical Translation. Journal of Materials Chemistry B. 2025. https://doi.org/10.1039/D5TB01405K 

Shah, S., Famta, P., Kumar, R. et al. QbD Manoeuvred Niclosamide Laden Polylactic-co-Glycolic Acid Nanoparticles-Impregnated Gelatin Nanofibers for the Management of Oral Carcinoma. BioNanoSci. 15, 221 (2025). https://doi.org/10.1007/s12668-025-01833-6 

Famta, P., Shah, S., Vambhurkar, G. et al. Establishment and Evaluation of Paclitaxel and Simvastatin-Laden Nanofibers for Post-surgical Tumor Recurrence in Breast Cancer. BioNanoSci. 15, 366 (2025). https://doi.org/10.1007/s12668-025-01935-1

Priyanshu Jaiswal, Giriraj Pandey, Shivam Kumar, Tejaswini Kolipaka, Shashi Kiran Misra, Shubham Kanaujiya, P.S. Rajinikanth, Saurabh Srivastava, Ajay Kumar Yadav, Advancements in skin tissue regeneration: Unveiling emerging treatment strategies, regulatory perspectives, and future directions for enhanced healing, Journal of Drug Delivery Science and Technology, Volume 108, 2025, 106872, ISSN 1773-2247, https://doi.org/10.1016/j.jddst.2025.106872.

Kunal Agam Kanaujia, Suraj Wagh, Giriraj Pandey, Vivek Phatale, Pooja Khairnar, Tejaswini Kolipaka, P.S. Rajinikanth, Shubhini A. Saraf, Saurabh Srivastava, Shailendra Kumar, Harnessing marine antimicrobial peptides for novel therapeutics: A deep dive into ocean-derived bioactives, International Journal of Biological Macromolecules, Volume 307, Part 3, 2025, 142158, ISSN 0141-8130, https://doi.org/10.1016/j.ijbiomac.2025.142158.

Swati Yadav, Dilip Kumar Arya, Shubham Kanaujiya, Santosh Kumar, Deepshikha Kushwaha, Anit Kumar, Prashant Pandey, Deshraj Deepak Kapoor, Abhishek Kumar, Ravi Kr. Gupta, Iffat Zareen Ahmed, and Parauvathanahalli Siddalingam Rajinikanth, ACS Applied Bio Materials 2025 8 (4), 2847-2866 DOI: 10.1021/acsabm.4c01532 

Arya, D. K. et al. (2025) ‘Dual-ligand functionalized liposomes with iRGD/trastuzumab co-loaded with gefitinib and lycorine for enhanced metastatic breast cancer therapy’, Journal of Liposome Research, pp. 1–15. https://doi.org/10.1080/08982104.2025.2457453.

Verma R, Kumar K, Bhatt S, Yadav M, Kumar M, Tagde P, et al. Untangling Breast Cancer: Trailing Towards Nanoformulations-based Drug Development. Vol. 19, Recent Patents on Nanotechnology. Bentham Science Publishers; 2025. p. 76–98. https://doi.org/10.2174/1872210517666230731091046

Shah, S., Famta, P., Vambhurkar, G., Kumar, R., Pandey, G., Singh, G., … Srivastava, S. (2025). Docetaxel and niclosamide-loaded nanofiber systems for improved chemo-therapeutic activity and resistance reversal in prostate cancer. Drug Development and Industrial Pharmacy, 51(2), 132–143. https://doi.org/10.1080/03639045.2025.2453533 

Zehra, F., Dwivedi, S., Ali, M.A. et al. Carcinogenic and non-carcinogenic risk estimation of indoor TVOCs, RSPM, FPM and SFPM on young women dwellers: a case study from the capital city of Uttar Pradesh, India. Discov Appl Sci 7, 86 (2025). https://doi.org/10.1007/s42452-025-06475-7 

Pandey, P., Arya, D.K., Kumar, A., Kaushik, A., Mishra, Y.K. and Rajnikanth, P.S., 2025. Dual Ligand Functionalized pH-Sensitive Liposomes for Metastatic Breast Cancer Treatment: In-vitro and in-vivo assessment. Journal of Materials Chemistry B. doi: https://doi.org/10.1039/D4TB02570A.

Kanaujiya, S. et al. (2024) ‘Resveratrol-Ampicillin Dual-Drug Loaded Polyvinylpyrrolidone/Polyvinyl Alcohol Biomimic Electrospun Nanofiber Enriched with Collagen for Efficient Burn Wound Repair’, International Journal of Nanomedicine, 19, pp. 5397–5418. https://www.tandfonline.com/doi/full/10.2147/IJN.S464046#d1e484 

Srivastava, D., Pandey, P., Tripathi, D.K., Yadav, J.P., Ali, B., Singh, V., Verma, A., Mishra, A., Kumar, D., Mishra, A. and Rajinikanth, P.S., 2024. Tasar Silkworm Pupae oil: A potential therapeutic and edible lipid source to mitigate the oxidative stress and cholesterol complications associated with diabetes. Food and Humanity, 3, p.100418. https://doi.org/10.1016/j.foohum.2024.100418 

Famta, P., Shah, S., Srinivasarao, D.A., Sharma, A., Kumar, R., Vambhurkar, G., Pandey, G., Prasad, S.B., Shinde, A., Asthana, A. and Ratna, P.K., 2024. Simvastatin-loaded gelatin-capped polycaprolactone nanoparticles for the post-operative management of breast cancer. Journal of Drug Delivery Science and Technology, 101, p.106163.  https://doi.org/10.1016/j.jddst.2024.106163 

Rishabh Chaudhary, Mujeeba Rehman, Vipul Agarwal, Anand Kumar, Arjun Singh Kaushik, Siddhi Srivastava, Sukriti Srivastava, Rajkumar Verma, P.S. Rajinikanth, Vikas Mishra, Terra incognita of glial cell dynamics in the etiology of leukodystrophies: Broadening disease and therapeutic perspectives, Life Sciences, Volume 354, 2024, 122953, ISSN 0024-3205, https://doi.org/10.1016/j.lfs.2024.122953.

Pandey, P., Chaudhary, R., Tripathi, D., Lavudi, K., Dua, K., Weinfeld, M., Lavasanifar, A. and Rajinikanth, P.S., 2024. Personalized treatment approach for HER2-positive metastatic breast cancer. Medical Oncology, 41(11), p.252. https://doi.org/10.1007/s12032-024-02504-4 

Arya, D.K., Deshpande, H., Kumar, A., Chidambaram, K., Pandey, P., Anjum, S., Deepak, P., Kumar, V., Kumar, S., Pandey, G. and Srivastava, S., 2024. HER-2 receptor and αvβ3 integrin dual-ligand surface-functionalized liposome for metastatic breast cancer therapy. Pharmaceutics, 16(9), p.1128. https://doi.org/10.3390/pharmaceutics16091128 

Pandey, P., Arya, D.K., Deepak, P., Ali, D., Alarifi, S., Srivastava, S., Lavasanifar, A. and Rajinikanth, P.S., 2024. αvβ3 integrin and folate-targeted pH-sensitive liposomes with dual ligand modification for metastatic breast cancer treatment. Bioengineering, 11(8), p.800. https://doi.org/10.3390/bioengineering11080800 

Anjum, S., Wang, Y., Xin, Y., Li, X., Li, T., Zhang, H., Quan, L., Li, Y., Arya, D.K., Rajinikanth, P.S. and Ao, Q., 2024. Bioinspired core-shell nanofiber drug-delivery system modulates osteogenic and osteoclast activity for bone tissue regeneration. Materials Today Bio, 26, p.101088. https://doi.org/10.1016/j.mtbio.2024.101088 

Correction to “Novel Synergistic Approach: Tazarotene-Calcipotriol-Loaded-PVA/PVP-Nanofiber Incorporated in Hydrogel Film for Management and Treatment of Psoriasis” Sunita Thakur, Md Meraj Anjum, Shweta Jaiswal, Anand Kumar, Payal Deepak, Sneha Anand, Sanjay Singh, and Paruvathanahalli Siddalingam Rajinikanth, Molecular Pharmaceutics 2024 21 (9), 4754-4756, DOI: 10.1021/acs.molpharmaceut.4c00635

Jaiswal, S., Anjum, M.M., Arya, D.K., Thakur, S., Pandey, P., Deepak, P., Kanaujiya, S., Anand, S., Kaushik, A.S., Mishra, V. and Rajinikanth, P.S., 2024. Surface entrenched β-sitosterol niosomes for enhanced cardioprotective activity against isoproterenol induced cardiotoxicity in rats. International Journal of Pharmaceutics, 653, p.123872. https://doi.org/10.1016/j.ijpharm.2024.123872 

Kanaujia, K.A., Mishra, N., Rajinikanth, P.S. and Saraf, S.A., 2024. Antimicrobial peptides as antimicrobials for wound care management: a comprehensive review. Journal of Drug Delivery Science and Technology, p.105570. https://doi.org/10.1016/j.jddst.2024.105570 

Nanda, A., Pandey, P., Rajinikanth, P.S. and Singh, N., 2024. Revolution of nanotechnology in food packaging: Harnessing electrospun zein nanofibers for improved preservation-A review. International Journal of Biological Macromolecules, p.129416. https://doi.org/10.1016/j.ijbiomac.2024.129416 

Tejaswini Kolipaka, Giriraj Pandey, Noella Abraham, Dadi A. Srinivasarao, Rajeev Singh Raghuvanshi, P.S. Rajinikanth, Vidya Tickoo, Saurabh Srivastava, Stimuli-responsive polysaccharide-based smart hydrogels for diabetic wound healing: Design aspects, preparation methods and regulatory perspectives, Carbohydrate Polymers, Volume 324, 2024, 121537, ISSN 0144-8617, https://doi.org/10.1016/j.carbpol.2023.121537.

Giriraj Pandey, Vivek Phatale, Pooja Khairnar, Tejaswini Kolipaka, Saurabh Shah, Paras Famta, Naitik Jain, Dadi A. Srinivasarao, P.S. Rajinikanth, Rajeev Singh Raghuvanshi, Saurabh Srivastava, Supramolecular self-assembled peptide-engineered nanofibers: A propitious proposition for cancer therapy, International Journal of Biological Macromolecules, Volume 256, Part 2, 2024, 128452, ISSN 0141-8130, https://doi.org/10.1016/j.ijbiomac.2023.128452.

Deepak, P., Kumar, P., Pandey, P., Arya, D.K., Jaiswal, S., Kumar, A., Sonkar, A.B., Ali, D., Alarifi, S., Ramar, M. and Rajinikanth, P.S., 2023. Pentapeptide cRGDfK-Surface Engineered Nanostructured Lipid Carriers as an Efficient Tool for Targeted Delivery of Tyrosine Kinase Inhibitor for Battling Hepatocellular Carcinoma. International Journal of Nanomedicine, pp.7021-7046. https://doi.org/10.2147/IJN.S438307 

Jaiswal, S., Anjum, M.M., Thakur, S., Pandey, P., Arya, D.K., Kumar, A., Kaushik, A.S. and Rajinikanth, P.S., 2023. Evaluation of cardioprotective effect of naringin loaded lignin nanoparticles against isoproterenol induced myocardial infarction. Journal of Drug Delivery Science and Technology, 89, p.105076. https://doi.org/10.1016/j.jddst.2023.105076 

Anjum, S., Li, T., Arya, D.K., Ali, D., Alarifi, S., Yulin, W., Hengtong, Z., Rajinikanth, P.S. and Ao, Q., 2023. Biomimetic electrospun nanofibrous scaffold for tissue engineering: preparation, optimization by design of experiments (DOE), in-vitro and in-vivo characterization. Frontiers in Bioengineering and Biotechnology, 11, p.1288539. https://doi.org/10.3389/fbioe.2023.1288539 

Anjum, M.M., Patel, K.K., Bhattacharya, S., Arya, D.K., Pandey, P., Vijayakumar, M.R., Singh, S. and Rajinikanth, P.S., 2023. Overcoming barriers in cystic fibrosis therapy through inhalational lipid nanoparticles: Challenges and advances. Journal of Drug Delivery Science and Technology, p.105068. https://doi.org/10.1016/j.jddst.2023.105068 

Thakur, S., Anjum, M.M., Jaiswal, S., Gautam, A.K. and Rajinikanth, P.S., 2023. Tazarotene-calcipotriol loaded Nanostructured lipid carrier enriched hydrogel: a novel dual drug synergistic approach towards Psoriasis management. Journal of Drug Delivery Science and Technology, 88, p.104944. https://doi.org/10.1016/j.jddst.2023.104944 

Anjum, S., Arya, D.K., Saeed, M., Ali, D., Athar, M.S., Yulin, W., Alarifi, S., Wu, X., Rajinikanth, P.S. and Ao, Q., 2023. Multifunctional electrospun nanofibrous scaffold enriched with alendronate and hydroxyapatite for balancing osteogenic and osteoclast activity to promote bone regeneration. Frontiers in Bioengineering and Biotechnology, 11, p.1302594. https://doi.org/10.3389/fbioe.2023.1302594 

Giriraj Pandey, Prashant Pandey, Dilip Kumar Arya, Shubham Kanaujiya, Deshraj Deepak Kapoor, Ravi Kr. Gupta, Shivendu Ranjan, Kumarappan Chidambaram, Balamurugan Manickam, P.S. Rajinikanth, Multilayered nanofibrous scaffold of Polyvinyl alcohol/gelatin/poly (lactic-co-glycolic acid) enriched with hemostatic/antibacterial agents for rapid acute hemostatic wound healing, International Journal of Pharmaceutics, Volume 638, 2023, 122918, ISSN 0378-5173, https://doi.org/10.1016/j.ijpharm.2023.122918.

Singh P, Pandey P, Arya DK, Anjum MM, Poonguzhali S, Kumar A, et al. Biomimicking dual drug eluting twisted electrospun nanofiber yarns for post-operative wound healing. Biomedical Materials. 2023 Mar;18(3):035006. DOI 10.1088/1748-605X/acc4a1 

Gautam, A.K., Kumar, P., Maity, B., Routholla, G., Ghosh, B., Chidambaram, K., Begum, M.Y., Al Fatease, A., Rajinikanth, P.S., Singh, S. and Saha, S., 2022. Synthesis and appraisal of dalbergin-loaded PLGA nanoparticles modified with galactose against hepatocellular carcinoma: In-vitro, pharmacokinetic, and in-silico studies. Frontiers in Pharmacology, 13, p.1021867.  https://doi.org/10.3389/fphar.2022.1021867 

Pandey, P., Arya, D.K., Ramar, M.K., Chidambaram, K. and Rajinikanth, P.S., 2022. Engineered nanomaterials as an effective tool for HER2+ breast cancer therapy. Drug Discovery Today, 27(9), pp.2526-2540. https://doi.org/10.1016/j.drudis.2022.06.007 

Anjum, S., Rahman, F., Pandey, P., Arya, D.K., Alam, M., Rajinikanth, P.S. and Ao, Q., 2022. Electrospun biomimetic nanofibrous scaffolds: a promising prospect for bone tissue engineering and regenerative medicine. International Journal of Molecular Sciences, 23(16), p.9206. https://doi.org/10.3390/ijms23169206 

Anand, S., Pandey, P., Begum, M.Y., Chidambaram, K., Arya, D.K., Gupta, R.K., Sankhwar, R., Jaiswal, S., Thakur, S. and Rajinikanth, P.S., 2022. Electrospun biomimetic multifunctional nanofibers loaded with ferulic acid for enhanced antimicrobial and wound-healing activities in STZ-Induced diabetic rats. Pharmaceuticals, 15(3), p.302. https://doi.org/10.3390/ph15030302 

Anand, S., Rajinikanth, P.S., Arya, D.K., Pandey, P., Gupta, R.K., Sankhwar, R. and Chidambaram, K., 2022. Multifunctional biomimetic nanofibrous scaffold loaded with asiaticoside for rapid diabetic wound healing. Pharmaceutics, 14(2), p.273. https://doi.org/10.3390/pharmaceutics14020273 

Gautam, A.K., Kumar, P., Raj, R., Kumar, D., Bhattacharya, B., Rajinikanth, P.S., Chidambaram, K., Mahata, T., Maity, B. and Saha, S., 2022. Preclinical evaluation of dimethyl itaconate against hepatocellular carcinoma via activation of the e/iNOS-mediated NF-κB–dependent apoptotic pathway. Frontiers in Pharmacology, 12, p.823285. https://doi.org/10.3389/fphar.2021.823285 

Yadav, S., Arya, D.K., Pandey, P., Anand, S., Gautam, A.K., Ranjan, S., Saraf, S.A., Rajamanickam, V.M., Singh, S., Chidambaram, K. and Alqahtani, T., 2022. ECM mimicking biodegradable nanofibrous scaffold enriched with curcumin/ZnO to accelerate diabetic wound healing via multifunctional bioactivity. International Journal of Nanomedicine, 17, p.6843. https://doi.org/10.2147/IJN.S388264  

Agarwal, Y., Rajinikanth, P.S., Ranjan, S., Tiwari, U., Balasubramnaiam, J., Pandey, P., Arya, D.K., Anand, S. and Deepak, P., 2021. Curcumin loaded polycaprolactone-/polyvinyl alcohol-silk fibroin based electrospun nanofibrous mat for rapid healing of diabetic wound: An in-vitro and in-vivo studies. International Journal of Biological Macromolecules, 176, pp.376-386. https://doi.org/10.1016/j.ijbiomac.2021.02.025 

Jaiswal S, Rajnikanth PS, Thakur S, Deepak P, Anand S. A Review on Novel Ligand Targeted Delivery for Cardiovascular Disorder. Vol. 18, Current Drug Delivery. Bentham Science Publishers; 2021. p. 1094–104. https://doi.org/10.2174/1567201818666210301095046 

Payal Deepak, Rajinikanth Siddalingam, Praveen Kumar, Sneha Anand, Sunita Thakur, Balasubramaniam Jagdish, Shweta Jaiswal, Gene based nanocarrier delivery for the treatment of hepatocellular carcinoma, Journal of Drug Delivery Science and Technology, Volume 59, 2020,101837, ISSN 1773-2247, https://doi.org/10.1016/j.jddst.2020.101837.

Kumar M, Shanthi N, Rajnikanth PS, Mahato AK. Authors Review on Drug Nanocrystals: A Progress to Targeted Delivery. Vol. 10, Current Nanomedicine. Bentham Science Publishers; 2020. p. 248–70.  https://doi.org/10.2174/2468187310666200221103827 

Kumar M, Rajnikanth PS. A Mini-review on HER2 Positive Breast Cancer and its Metastasis: Resistance and Treatment Strategies. Vol. 10, Current Nanomedicine. Bentham Science Publishers; 2020. p. 36–47. https://doi.org/10.2174/2468187310666191223141038 

Subramanian P, Rajnikanth PS, Kumar M, Chidambram K. In-Vitro and In-Vivo Evaluation of Supersaturable Self-Nanoemulsifying Drug Delivery System (SNEDDS) of Dutasteride. Vol. 17, Current Drug Delivery. Bentham Science Publishers; 2020. p. 74–86. https://doi.org/10.2174/1567201816666191112111610 

Rajnish Kumar Yadav, Chandra Bhusan Tripathi, Shubhini A. Saraf, Mohd Nazam Ansari, Abdulaziz S. Saeedan, Sara Aldosary, Paruvathanahalli S. Rajinikanth, Gaurav Kaithwas, Alpha-linolenic acid based nano-suspension protect against lipopolysaccharides induced mastitis by inhibiting NFκBp65, HIF-1α, and mitochondria-mediated apoptotic pathway in albino Wistar rats, Toxicology and Applied Pharmacology, Volume 377, 2019, 114628, ISSN 0041-008X, https://doi.org/10.1016/j.taap.2019.114628.

Kumar M, Shanthi N, Mahato AK, Soni S, Rajnikanth PS. Preparation of luliconazole nanocrystals loaded hydrogel for improvement of dissolution and antifungal activity. Heliyon. 2019 May;5(5):e01688. https://doi.org/10.1016/j.heliyon.2019.e01688 

Self-Nanoemulsifying Drug Delivery Systems of Poorly Soluble Drug Dutasteride: Formulation and In-Vitro characterization. J App Pharma Sci [Internet]. 2017 [cited 2025 July 19]; Available from: http://www.japsonline.com/abstract.php?article_id=2216

Ong TH, Chitra E, Ramamurthy S, Siddalingam RP, Yuen KH, Ambu SP, et al. Chitosan-propolis nanoparticle formulation demonstrates anti-bacterial activity against Enterococcus faecalis biofilms. PLOS ONE. 2017 Mar 31;12(3):e0174888.