The Mono Project

Epstein-Barr Virus Diseases Research

Our Research

Our research mission is to learn how Epstein-Barr virus (EBV) causes disease and to develop a vaccine against it.


Epstein-Barr virus (EBV) infects at least 90% of the adult population worldwide and is the primary cause of infectious mononucleosis. EBV is also the cause or the major risk factor for several forms of cancer, including Burkitt lymphoma, Hodgkin lymphoma, and nasopharyngeal carcinoma. EBV is also the leading cause of posttransplant lymphoproliferative disorder in solid organ and hematopoietic cell (bone marrow) transplant patients. Additionally, new research strengthens the evidence that EBV is involved in the pathogenesis of multiple sclerosis.

Epstein-Barr Virus Vaccine

Our hypothesis is that a prophylactic EBV vaccine could prevent or reduce the severity of all EBV-associated illnesses. Researchers at the Mono Project are actively collaborating with researchers at the NIH to perform clinical trials of candidate EBV vaccines.

Chronic Mono

Chronic mono follows an EBV infection with two patterns, including continuous illness persisting after the onset or recovery from the acute illness but lingering or recurring symptoms for years. For advice on managing chronic mono click here to download our treatment suggestions for antiviral drugs and diet. All treatments should be followed under the direct supervision of a physician.

Watch an Interview with Dr. Balfour

Disclaimer

The education and information presented here within The Mono Project website, social media, emails, or other documentation is intended for a general audience and does not purport to be, nor should it be construed as, specific advice tailored to any individual. Do not disregard, avoid, or delay obtaining medical or health related advice from your health-care professional because of something you may read from The Mono Project. The use of any information provided by The Mono Project and any related peoples is solely at your own risk. You should not rely on this information as a substitute for, nor does it replace, professional medical advice, diagnosis, or treatment. If you have any concerns or questions about your health, you should always consult with a physician or other health-care professional. The health, wellness, fitness, and all information offered by The Mono Project and associated peoples with The Mono Project is designed for educational purposes only.