Publications

Recent Publications (from >155)

Tachibana, Y., Sasai, M., Kosako, H., Takashima, E., Carruthers, V.B., Soldati-Favre, D., Yamamoto, M. (2026) An in vivo fitness gene of Toxoplasma, MIC11, is essential for PLP1-mediated egress from host cells. Nature Communications(in press). Apr 4;17(1):4895. doi: 10.1038/s41467-026-71423-x. (PMC1320962).

Borel, T.J., Hitchens, J.R., Kaur, H., Meuller, D., Ard, A.J., Carruthers, V.B.*, Clasby, M.C.* (2026) Improvements in selectivity of triazine nitrile inhibitors targeting Toxoplasma gondii Cathepsin L for the treatment of latent toxoplasmosis. Bioorganic Medicinal Chemistry.  138:118643. doi: 10.1016/j.bmc.2026.118643. *co-corresponding authors.

Rimple, P.A., Olafsson, E.B., Markus, B.M., Wang, F., Augusto, L., Lourido, S., Carruthers, V.B. (2025) Metabolic adaptability and nutrient scavenging in Toxoplasma gondii: insights from ingestion pathway-deficient mutants. mSphere. Apr 29;10(4):e0101124. 10(4):e0101124. doi: 10.1128/msphere.01011-24. (PMC12039266).

Thaprawat, P., Chalasani, S., Wang, F., Di Cristina, M., Carruthers, V.B. (2025) Toxoplasma gondii PROP1 is critical for autophagy and parasite viability during chronic infection. mSphere. 10(3):e0082924. doi: 10.1128/msphere.00829-24. (PMC11934330).

Frey, H.C., Sun, X., Oudeif, F., Corona, D., He, Z., Won, T., Schultz, T., Carruthers, V.B., Laouar, A., Laouar, Y. (2025) A membrane lipid signature unravels the dynamic landscape of group 1 ILCs. iScience. 28(3):112043. doi: 10.1016/j.isci.2025.112043. (PMC11914809).

Messina, G., Goerner, A., Bennet, C., Brennan, E. L., Carruthers, V.B., Martorelli Di Genova, B. (2025) Impact of equilibrative nucleoside transporters TgAT1, TgENT1, and TgENT2 on Toxoplasma gondii infection and differentiation. mBio. Nov 12;16(11):e0220725. doi: 10.1128/mbio.02207-25. (PMC12607627).

Waller, R.F., Carruthers, V.B. (2024) Adaptations and metabolic evolution of myzozoan protists across diverse lifestyles and environments. Microbiology and Molecular Biology Reviews. Oct 10:e0019722. doi: 10.1128/mmbr.00197-22. (PMC39387988)

Thaprawat, P., Zhang, Z., Rentchler, E., Wang, F., Chalasani, S., Giuliano, C., Lourido, S., Di Cristina, M., Klionsky, D.J., Carruthers, V.B. (2024) TgATG9 is required for autophagosome biogenesis and maintenance of chronic infection in Toxoplasma gondii. Autophagy Reports. 3(1):2418256. doi: 10.1080/27694127.2024.2418256. (PMC11588310).

Carruthers, V.B. (2024) Parasite pore-forming toxins. Annual Reviews of Microbiology. Aug 1. doi:10.1146/annurev-micro-041222-025939.

Wang, F., Holmes, M.J., Hong H.J., Thaprawat, P., Kannan, G., Huynh, M.-H., Schultz, T.L., Licon, M.H., Lourido, S., Dong, W., Brito Querido, J., Sullivan Jr., W.J., O’Leary, S.E., Carruthers, V.B. (2024) Translation initiation factor eIF1.2 promotes Toxoplasma stage conversion by regulating levels of key differentiation factors. Nat. Comm. May 23;15(1):4385. doi: 10.1038/s41467-024-48685-4. (PMC11116398).

Piro, F., Masci, S., Kannan, G., Focaia, R., Schultz, T.L., Thaprawat, P., Carruthers, V.B.*, and Di Cristina, M.* (2024) A Toxoplasma gondii putative arginine transporter localizes to the plant-like vacuolar compartment and controls parasite extracellular survival and stage differentiation. mSphere. Jan 30;9(1):e0059723. doi: 10.1128/msphere.00597-23. Epub 2023 Dec 5. *co-corresponding authors. (PMC10871165).