Publications - year -

2026

• Metformin suppresses β-cell apoptosis under ER stress by inhibiting protein translation  Inoue R and Tajima K et al  Mol Metab 2026

2025

• Glycine receptor activation promotes pancreatic islet cell proliferation via the PI3K/mTORC1/p70S6K pathway  Zhang Z et al  JCI Insight 2025

• Furin may contribute to proglucagon processing and glucagon-like peptide-1 production in human alpha cells  Koepke J et al Mol Metab 2025

• Benchmarking porcine pancreatic ductal organoids for drug screening applications  Karampelias C et al  EMBO Mol Med 2025 

• Truncated CD19 as a selection marker for the isolation of stem cell derived β-cells  Huang LT et al  Dis Model Mech 2025 

• Adenylosuccinate mediates imeglimin-induced proliferative and anti-apoptotic actions in β-cells  Inoue R et al  Diabetes 2025

• High glucose burden disrupts the glucose responsiveness of human pancreatic beta cells encapsulated in alginate fibers during long-term culture  Yabe S et al  Gene 2025

• Molecular correlates of glycine receptor activity in human β cells  Gomes AS et al  Mol Metab 2025  

• Imeglimin suppresses glucagon secretion and induces a loss of α-cell identity  Tsuno T et al  Cell Rep Med 2025

• TMEM55A-mediated PI5P signaling regulates α-cell actin depolymerization and glucagon secretion  Liu X et al  Diabtologia 2025

• The matricellular protein Fibulin-5 regulates β-cell proliferation through autocrine/paracrine manner  Okuyama T et al  iScience 28:111856, 2025

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