國科會專題研究計畫 (National Science and Technology Council, Taiwan) 2024/08/1 - 2025/07/31:
Assessing the impacts of the emergence of toxigenic M1UK and SSA-positive M1 clones on group A Streptococcus infection in Taiwan (評估新興M1UK毒性株及SSA陽性M1株對台灣化膿性鏈球菌感染之衝擊)
長庚醫院研究計畫 (Chang Gung Memorial Hospital at Linkou, Taiwan) 2022/12/01 - 2024/11/30:
Development of molecular typing approaches for Clostridium innocuum and characterization of the interaction between C. innocuum and Clostridioides difficile (無害梭狀芽孢桿菌之分子分型及其與困難梭狀芽孢桿菌之交互影響) [整合型研究計畫]
長庚醫院研究計畫 (Chang Gung Memorial Hospital at Linkou, Taiwan) 2024/10/01 - 2025/09/30:
Characterization of a new acapsular group A Streptococcus clade of genotype emm89 in the Linkou Chang Gung Memorial Hospital (林口長庚紀念醫院新無莢膜emm89基因型A 群鏈球菌菌株之分析)
國科會專題研究計畫 (National Science and Technology Council, Taiwan) 2025/08/1 - 2028/07/31:
Role of two-component regulatory system CovR/CovS-mediated bacterial cell wall thickness reduction on extracellular vesicle release, ExPortal microdomain integrity, and LiaF/LiaS/LiaR three-component regulation system activation in group A Streptococcus (CovR/CovS二元調控系統引發細胞壁厚度的減少對A群鏈球菌胞外囊泡釋放，ExPortal微區域完整性，及LiaF/LiaS/LiaR三元調控系統活化之角色)
科技部專題研究計畫 (National Science and Technology Council, Taiwan) 2021/08/1 - 2024/07/31:
Endopeptidase as the diagnostic marker and the key mediator of CovR/CovS and Rgg interaction in invasive group A Streptococcus (內胜肽酶作為侵襲性化膿性鏈球菌之診斷標的以及CovR/CovS與Rgg調控系統互動之重要媒介. 1/3, 2/3, 3/3) [優秀年青學者研究計畫]
科技部專題研究計畫 (National Science and Technology Council, Taiwan) 2021/08/1 - 2024/07/31:
CovR/CovS two-component regulatory system and quorum-sensing regulator Rgg on modulating extracellular vesicle production under acidic stress in group A Streptococcus (CovR/CovS 二元調控系統與群體感應調控因子Rgg調控A群鏈球菌於酸性壓力下生產胞外囊泡之機制. 1/3, 2/3, 3/3) [整合型研究計畫]
長庚醫院研究計畫 (Chang Gung Memorial Hospital at Linkou, Taiwan) 2021/07/01 - 2022/12/31:
Investigation of the molecular mechanisms of vancomycin-tolerant phenotype and increased biofilm formation in in vitro selected vancomycin-intermediate Staphylococcus argenteus (研究體外篩選萬古黴素中間型銀色葡萄球菌之萬古黴素敏感性降低及生物膜表現量上升的分子機制)
長庚醫院研究計畫 (Chang Gung Memorial Hospital at Linkou, Taiwan) 2019/04/01 - 2022/03/31:
Epidemiological characterization and pathogenicity of invasive group A Streptococcus (侵襲性A型鏈球菌流行病學及致病特性之分析)
科技部專題研究計畫 (National Science and Technology Council, Taiwan) 2020/08/1 - 2021/07/31:
Role of Rgg in the pathogenesis of invasive covR/covS mutants of group A Streptococcus (探討Rgg於侵襲性A群鏈球菌 covR/covS 突變株致病機制之角色)
長庚醫院研究計畫 (Chang Gung Memorial Hospital at Linkou, Taiwan) 2020/07/01 - 2021/06/30:
Mechanisms of invasive acapsular group A Streptococcus resistance to the intracellular killing of phagocytic cells (探討侵襲性莢膜缺失之A群鏈球菌抵禦吞噬細胞清除之機制)
科技部專題研究計畫 (National Science and Technology Council, Taiwan) 2017/08/1 - 2020/07/31:
Regulation of Rgg regulon by CovR/CovS system in group A Streptococcus (化膿性鏈球菌 CovR/CovS 系統對 Rgg 調節子之調控)
長庚醫院研究計畫 (Chang Gung Memorial Hospital at Linkou, Taiwan) 2017/08/01 - 2020/07/31:
Mechanism of CovS regulates covR transcription in invasive group A streptococci (研究侵襲性A群鏈球菌中CovS調控covR轉錄之分子機制)
長庚醫院研究計畫 (Chang Gung Memorial Hospital at Linkou, Taiwan) 2015/06/01 - 2018/11/30:
Intracellular infection and pathogenesis of invasive group A streptococci (侵襲性化膿性鏈球菌胞內感染於其致病機制之角色)
科技部專題研究計畫 (National Science and Technology Council, Taiwan) 2014/08/01 - 2017/07/31:
Selective advantages of invasive emm1 type group A Streptococcus under acidic stress (探討侵襲性 emm1 型 A 群鏈球菌於酸性壓力下之選擇性優勢)
長庚醫院研究計畫 (Chang Gung Memorial Hospital at Linkou, Taiwan) 2016/06/01 - 2017/05/31:
Study of transcriptional and translational level regulations of two-component regulatory system CovR/CovS in group A Streptococcus ( 研究化膿性鏈球菌二元調控系統 CovR/CovS 於轉錄及轉譯層次之調控)
長庚醫院研究計畫 (Chang Gung Memorial Hospital at Linkou, Taiwan) 2013/03/01 - 2015/02/28:
Pathogenic relevance of colony morphology and phenotype changes by group A Streptococcus (A 群鏈球菌菌落型態及表現型轉變與其致病能力變化之相關性)
國家科學委員會 (National Science and Technology Council, Taiwan) 2012/09/01 - 2013/08/31:
Pathogenic roles for CovS sensing acidic stress in group A Streptococcus (探討 CovS 酸性壓力感知能力於 A 群鏈球菌致病過程之角色)