Publications

 Publications PubMed

2022

Bhatia S, Hunter CP.  SID-4/NCK-1 is important for dsRNA import in Caenorhabditis elegans.

G3 (Bethesda). 2022 Nov 4;12(11):jkac252. doi: 10.1093/g3journal/jkac252.

Bush NM, Hunter CP. Don't put all your epigenetic eggs in one basket. Nat Cell Biol 2022 Jul;24(7):1016-1018. doi: 10.1038/s41556-022-00948-2. 

2019 

Ge XA, Hunter CP. Efficient Homologous Recombination in Mice Using Long Single Stranded DNA and CRISPR Cas9 Nickase. G3 (Bethesda). 2019 Jan 9;9(1):281-286. doi: 10.1534/g3.118.200758.PMID: 30504134 

2017

Minkina O, Hunter CP. Intergenerational Transmission of Gene Regulatory Information in Caenorhabditis elegans. Trends Genet. 2018 Jan;34(1):54-64. doi: 10.1016/j.tig.2017.09.012. Epub 2017 Nov 2. Review. PMID:29103876

Whangbo JS, Weisman AS, Chae J, Hunter CP. SID-1 Domains Important for dsRNA Import in Caenorhabditis elegans. G3 (Bethesda). 2017 Dec 4;7(12):3887-3899. doi: 10.1534/g3.117.300308.PMID:29025917

Nguyen TA, Smith BRC, Tate MD, Belz GT, Barrios MH, Elgass KD, Weisman AS, Baker PJ, Preston SP, Whitehead L, Garnham A, Lundie RJ, Smyth GK, Pellegrini M, O'Keeffe M, Wicks IP, Masters SL, Hunter CP, Pang KC. SIDT2 Transports Extracellular dsRNA into the Cytoplasm for Innate Immune Recognition. Immunity. 2017 Sep 19;47(3):498-509.e6. doi: 10.1016/j.immuni.2017.08.007. Epub 2017 Sep 12. PMID:28916264

Wang E, Hunter CP. SID-1 Functions in Multiple Roles To Support Parental RNAi in Caenorhabditis elegans. Genetics. 2017 Oct;207(2):547-557. doi: 10.1534/genetics.117.300067. Epub 2017 Jul 27. PMID:28751423

Shiu PK, Hunter CP. Early Developmental Exposure to dsRNA Is Critical for Initiating Efficient Nuclear RNAi in C. elegans. Cell Rep. 2017 Mar 21;18(12):2969-2978. doi:10.1016/j.celrep.2017.03.002.PMID: 28329688

Minkina O, Hunter CP. Stable Heritable Germline Silencing Directs Somatic Silencing at an Endogenous Locus. Mol Cell. 2017 Feb 16;65(4):659-670.e5. doi:10.1016/j.molcel.2017.01.034. PMID: 28212751

2015

Huang NN, Hunter CP. (2015) The RNA binding protein MEX-3 retains asymmetric activity in the early Caenorhabditis elegans embryo in the absence of asymmetric protein localization. Gene. PMID: 25445286

2014

Schott D, Yanai I, Hunter CP (2014) Natural RNA interference directs a heritable response to the environment. Sci Rep. PMID: 25552271

Shiu PK(1), Zhuang JJ, Hunter CP. (2014) Assays for direct and indirect effects of C. elegans endo-siRNAs. Methods Mol Biol. PMID: 24920361

2012 

Zhuang, JJ, and Hunter, CP. (2012) The Influence of Competition Among C. elegans Small RNA Pathways on Development. Genes (Basel), 3(4). PMID: 23483754 PMC3592204.

Zhuang JJ, Banse SA, Hunter CP. (2012) The nuclear argonaute NRDE-3 contributes to transitive RNAi in Caenorhabditis elegans. Genetics. 194(1):117-31. PMID: 23457236; PMCID PMC3632460.

Hinas A, Wright AJ, Hunter CP. (2012) SID-5 is an endosome-associated protein required for efficient systemic RNAi in C. elegans. Curr Biol. 22:1938-43. PMID:22981770. 

Jose AM, Kim YA, Leal-Ekman S, Hunter CP. (2012) Conserved tyrosine kinase promotes the import of silencing RNA into Caenorhabditis elegans cells. Proc Natl Acad Sci U S A. 109(36):14520-5. PMID: 22912399; PMCID: PMC3437824. 

McEwan DL, Weisman AS, Hunter CP. (2012) Uptake of extracellular double-stranded RNA by SID-2. Mol Cell. 47(5):746-54. PMID: 22902558 PMC3488460. 

Grishkevich V, Ben-Elazar S, Hashimshony T, Schott DH, Hunter CP, Yanai I. (2012) A genomic bias for genotype-environment interactions in C. elegans. Mol Syst Biol. 8:587. PMID: 22669615 PMC3397417. 

Banse SA, Hunter CP. (2012) Vampiric isolation of extracellular fluid from Caenorhabditis elegans. J Vis Exp. (61). PMID: 22453516. 

Zhuang JJ, Hunter CP. (2012) RNA interference in Caenorhabditis elegans: uptake, mechanism, and regulation. Parasitology. 139(5):560-73. PMID: 22075748.

2011

Jose AM, Garcia GA, Hunter CP. (2011) Two classes of silencing RNAs move between Caenorhabditis elegans tissues. Nat Struct Mol Biol. 2011 18(11):1184-8. PMID: 21984186; PMC3210371.

Shih JD, Hunter CP. (2011) SID-1 is a dsRNA-selective dsRNA-gated channel. RNA.17(6):1057-65. PMID: 21474576 PMC3096038. 

Zhuang JJ, Hunter CP. (2011) Tissue specificity of Caenorhabditis elegans enhanced RNA interference mutants. Genetics. 188:235-7 PMID: 21385728; PMC3120140.

2010

Gil-Krzewska AJ, Farber E, Buttner EA, Hunter CP. (2010) Regulators of the actin cytoskeleton mediate lethality in a Caenorhabditis elegans dhc-1 mutant. Mol Biol Cell. 21(15):2707-20. PMID: 20554764; PMC2912356. 

Shen-Orr SS, Pilpel Y, Hunter CP. (2010) Composition and regulation of maternal and zygotic transcriptomes reflects species-specific reproductive mode. Genome Biol. 11(6):R58. PubMed PMID: 20515465, PMC2911106.

2009

Yanai I, Hunter CP. (2009) Comparison of diverse developmental transcriptomes reveals that coexpression of gene neighbors is not evolutionarily conserved. Genome Res. 19(12):2214-20. PMID: 19745112; PMC2792179. 

Yung YC, Chae J, Buehler MJ, Hunter CP, Mooney DJ.(2009) Cyclic tensile strain triggers a sequence of autocrine and paracrine signaling to regulate angiogenic sprouting in human vascular cells. Proc Natl Acad Sci U S A. 106(36):15279-84. PMID: 19706407; PMC2741242.

Jose, AM, Smith, JJ, and Hunter, CP. (2009) Export of RNA silencing from C. elegans tissues does not require the RNA channel SID-1. Proc. Natl. Acad. Sci. U.S.A., 106(7):2283-8. PMID: 19168628  PMC2650148

Shih, JD, Fitzgerald, MC, Sutherlin, M, and Hunter, CP. (2009) The SID-1 double-stranded RNA transporter is not selective for dsRNA length. RNA, 15(3):384-90. PMID: 19155320  PMC265700

2008

Whangbo, JS, and Hunter, CP. (2008) Environmental RNA interference. Trends Genet., 24(6):297-305. PMID: 18450316  

Yanai I, Baugh LR, Smith JJ, Roehrig C, Shen-Orr SS, Claggett JM, Hill AA, Slonim DK, Hunter CP. (2008) Pairing of competitive and topologically distinct regulatory modules enhances patterned gene expression. Mol Syst Biol. 4:163. PMID: 18277379; PMC2267734.

2007

Jose, AM, and Hunter, CP. (2007) Transport of sequence-specific RNA interference information between cells. Annu. Rev. Genet., 41:305-30. PMID: 17645412  

Winston, WM, Sutherlin, M, Wright, AJ, Feinberg, EH, and Hunter, CP. (2007) Caenorhabditis elegans SID-2 is required for environmental RNA interference. Proc. Natl. Acad. Sci. U.S.A., 104(25):10565-70. PMID: 17563372  PMC1965553

Buttner EA, Gil-Krzewska AJ, Rajpurohit AK, Hunter CP. (2007) Progression from mitotic catastrophe to germ cell death in Caenorhabditis elegans lis-1 mutants requires the spindle checkpoint. Dev Biol. 305(2):397-410. PMID: 17376425; PMC2000799.

2006

Baugh LR, Hunter CP. (2006) MyoD, modularity, and myogenesis: conservation of regulators and redundancy in C. elegans. Genes Dev. 20(24):3342-6. PubMed PMID: 17182863.

Hunter CP, Winston WM, Molodowitch C, Feinberg EH, Shih J, Sutherlin M, Wright AJ, Fitzgerald MC. Systemic RNAi in Caenorhabditis elegans. Cold Spring Harb Symp Quant Biol. 71:95-100. PMID: 17381285.

2005

Schott, DH, Cureton, DK, Whelan, SP, and Hunter, CP. (2005) An antiviral role for the RNA interference machinery in Caenorhabditis elegans. Proc. Natl. Acad. Sci. U.S.A., 102(51):18420-4. PMID: 16339901  PMC1317933

Lanjuin A, Claggett J, Shibuya M, Hunter CP, Sengupta P. (2005) Regulation of neuronal lineage decisions by the HES-related bHLH protein REF-1. Dev Biol. 90(1):139-51. PMID: 16376329. 

Baugh LR, Wen JC, Hill AA, Slonim DK, Brown EL, Hunter CP. (2005) Synthetic lethal analysis of Caenorhabditis elegans posterior embryonic patterning genes identifies conserved genetic interactions. Genome Biol. 6(5):R45. PMID: 15892873; PMC1175957. 

Baugh LR, Hill AA, Claggett JM, Hill-Harfe K, Wen JC, Slonim DK, Brown EL, Hunter CP. (2005) The homeodomain protein PAL-1 specifies a lineage-specific regulatory network in the C. elegans embryo. Development. 132(8):1843-54. PMID: 15772128.

Evans TC, Hunter CP. Translational control of maternal RNAs. WormBook. 2005 1-11. PMID: 18050410.

2004

Mootz D, Ho DM, Hunter CP. (2004) The STAR/Maxi-KH domain protein GLD-1 mediates a developmental switch in the translational control of C. elegans PAL-1. Development. 131(14):3263-72. PMID: 15201219.

2003

Feinberg, EH, and Hunter, CP. (2003) Transport of dsRNA into cells by the transmembrane protein SID-1. Science, 301(5639):1545-7. PMID: 12970568  

Wright AJ, Hunter CP. (2003) Mutations in a beta-tubulin disrupt spindle orientation and microtubule dynamics in the early Caenorhabditis elegans embryo. Mol Biol Cell. 14(11):4512-25. PMID: 12937270; PMC268303. 

Baugh LR, Hill AA, Slonim DK, Brown EL, Hunter CP. (2003) Composition and dynamics of the Caenorhabditis elegans early embryonic transcriptome. Development.130(5):889-900. PMID: 12538516.

2002

Winston, WM, Molodowitch, C, and Hunter, CP. (2002) Systemic RNAi in C. elegans requires the putative transmembrane protein SID-1. Science, 295(5564):2456-9. PMID: 11834782  

Huang NN, Mootz DE, Walhout AJ, Vidal M, Hunter CP. (2002) MEX-3 interacting proteins link cell polarity to asymmetric gene expression in Caenorhabditis elegans. Development 129(3):747-59. PMID: 11830574.

2001

Hill AA, Brown EL, Whitley MZ, Tucker-Kellogg G, Hunter CP, Slonim DK. (2001) Evaluation of normalization procedures for oligonucleotide array data based on spiked cRNA controls. Genome Biol. 2(12):RESEARCH0055. PMID: 11790258; PMC64840.

Kay AJ, Hunter CP. (2001) CDC-42 regulates PAR protein localization and function to control cellular and embryonic polarity in C. elegans. Curr Biol. 11(7):474-81. PMID: 11412996. 

Baugh LR, Hill AA, Brown EL, Hunter CP. (2001) Quantitative analysis of mRNA amplification by in vitro transcription. Nucleic Acids Res. 2001 Mar 1;29(5):E29. PMID: 11222780; PMC29742.

2000

Hunter, CP. (2000) Gene silencing: shrinking the black box of RNAi. Curr. Biol., 10(4):R137-40. PMID: 10704407  

Hill AA, Hunter CP, Tsung BT, Tucker-Kellogg G, Brown EL. (2000) Genomic analysis of gene expression in C. elegans. Science 290(5492):809-12.PMID: 11052945.

1999

Hunter, CP. (1999) Genetics: a touch of elegance with RNAi. Curr. Biol., 9(12):R440-2. PMID: 10375522

Hunter CP, Harris JM, Maloof JN, Kenyon C. (1999) Hox gene expression in a single Caenorhabditis elegans cell is regulated by a caudal homolog and intercellular signals that inhibit wnt signaling. Development.126(4):805-14. PMID: 9895327.

1997

Bowerman B, Ingram MK, Hunter CP. (1997) The maternal par genes and the segregation of cell fate specification activities in early Caenorhabditis elegans embryos. Development 124(19):3815-26. PMID: 9367437.

Kenyon CJ, Austin J, Costa M, Cowing DW, Harris JM, Honigberg L, Hunter CP, Maloof JN, Muller-Immerglück MM, Salser SJ, Waring DA, Wang BB, Wrischnik LA. The dance of the Hox genes: patterning the anteroposterior body axis of Caenorhabditis elegans. Cold Spring Harb Symp Quant Biol. 62:293-305. PMID: 9598363.

1996

Hunter CP, Kenyon C. (1996) Spatial and temporal controls target pal-1 blastomere-specification activity to a single blastomere lineage in C. elegans embryos. Cell 87(2):217-26. PMID: 8861906.

1995

Hunter CP, Kenyon C. (1995) Specification of anteroposterior cell fates in Caenorhabditis elegans by Drosophila Hox proteins. Nature. 377(6546):229-32. PMID: 7675107.

1992

Hunter CP, Wood WB. (1992) Evidence from mosaic analysis of the masculinizing gene her-1 for cell interactions in C. elegans sex determination. Nature. 355(6360):551-5. PMID: 1741033. 1991

1991

Schedin P, Hunter CP, Wood WB. (1991) Autonomy and nonautonomy of sex determination in triploid intersex mosaics of C. elegans. Development. 112(3):863-79 PMID: 1935692.

Hunter CP, Wood WB. (1990) The tra-1 gene determines sexual phenotype cell-autonomously in C. elegans. Cell. 63(6):1193-204. PMID: 2261640. 1987

Valls LA, Hunter CP, Rothman JH, Stevens TH. (1987) Protein sorting in yeast: the localization determinant of yeast vacuolar carboxypeptidase Y resides in the propeptide. Cell. 48(5):887-97. PMID: 3028649.

1986

Ammerer G, Hunter CP, Rothman JH, Saari GC, Valls LA, Stevens TH. (1986) PEP4 gene of Saccharomyces cerevisiae encodes proteinase A, a vacuolar enzyme required for processing of vacuolar precursors. Mol Cell Biol. 6(7):2490-9. PMID: 3023936; PMC367803.

Rothman JH, Hunter CP, Valls LA, Stevens TH. (1986) Overproduction-induced mislocalization of a yeast vacuolar protein allows isolation of its structural gene. Proc Natl Acad Sci U S A.83(10):3248-52. PubMed PMID: 3517855; PMC323490.