Personnels
Jian Zhu, PhD
Principal Investigator
Professor, The Ohio State University Medical Center
Associate Professor, The Ohio State University Medical Center
Assistant Professor, University of Rochester Medical Center
Trainings
Postdoc Fellow, Harvard Medical School
PhD, Johns Hopkins University College of Medicine
BS, Peking University Health Science Center
Research Focuses
My lab studies virus-host interaction, viral oncology, and antiviral immunity. We work at the interface of virology, immunology, oncology, genetics, cellular and molecular biology. We identify novel epigenetic and epitranscriptional regulators that control viral evasion and antiviral immune response, particularly for HIV, herpesviruses (EBV, KSHV), emerging and re-emerging viruses (SARS-CoV-2, influenza, zika), by using modern functional genomic (RNAi, CRISPR/Cas9) and quantitative proteomic (MS, PLATO) approaches. We further dissect the mechanistic functions of these key host regulators using classic cell and/or animal models of viral infection. Newly developed small-molecule compounds targeting epigenetic and epitranscriptional regulators are investigated as the next-generation antiviral reagents and/or immune modulators.
Guillaume Fiches, PhD
Research Scientist
PhD, University of Adelaide, South Australia, Australia
BS, National Institute of Applied Sciences (INSA), Lyon, France
Co-mentored with Dr Netty Santoso at Pathology of OSUMC
Dawei Zhou, PhD
Research Scientist
PhD, Chinese Academy of Sciences, Wuhan, China
BS, Shandong Agricultural University, Tai'an, China
Jinshan He, PhD
Research Scientist
PhD, Kyoto University, Kyoto, Japan
MS, Kyoto Institute of Technology, Kyoto, Japan
BS, Liaoning University, Shenyang, China
Jianwen Chen, PhD
Postdoctoral Fellow
PhD, Anhui Agriculture University, Hefei, China
MS, Anhui Agriculture University, Hefei, China
BS, Anhui Agriculture University, Hefei, China
Kateepe Arachchige Shanaka, PhD
Postdoctoral Fellow
PhD, Jeju National University, Jeju-do, South Korea
BS, University of Colombo, Colombo, Sri Lanka
Thurbu Tshering Lepcha, PhD
Postdoctoral Fellow
PhD, Calcutta University, Kolkata, India
MS, Maulana Abul Kalam Azad University of Technology, Kolkata, India
BS, Maulana Abul Kalam Azad University of Technology, Kolkata, India
Yan Liu, PhD
Postdoctoral Fellow
PhD, Zhejiang University, Hangzhou, China
MS, Northwest A & F University., Xianyang, China
BS, Northwest A & F University., Xianyang, China
Youngmin Park
Graduate Student, Molecular Genetics program
BS, Oregon State University, Corvallis, Oregon, United States
Zhenyu Wu
Graduate Student, MCDB program
BS, Wuhan University, Wuhan, China
Co-mentored with Dr Netty Santoso at Pathology of OSUMC
Emily Watters
Undergraduate Student, Microbiology
Ohio State University
Zhixian Michele He
Undergraduate Student, Health and Rehabilitation Science
Ohio State University
Carter Krannitz
Undergraduate Student, Chemistry Pre-Med
Ohio State University
Zhu Lab 2018
Zhu Lab 2023
Lab Alumni
Postdoc Fellows:
Dr Danillo Esposito (currently at Nationwide Children Hospital)
Dr Tsuyoshi Hayashi (currently at National Institute of Infectious Diseases Tokyo)
Dr Huachao Huang (currently at Columbia University Medical Center)
Dr Weili Kong (currently at Gladstone Institutes of UCSF Medical Center)
Dr Ayan Biswas (currently at University of Alabama at Birmingham)
Students:
Tai-Wei Li (PhD student, thesis, currently a postdoc fellow at the Seattle Children's Hospital of the University of Washington School of Medicine)
Yinchong Wang (PhD student, currently a PhD candidate at OSU MCDB program)
Anushka Ruwanpathirana (PhD student, currently a PhD candidate at OSU BSGP program)
Samiha Kabir (PhD student, currently a PhD candidate at OSU MCDB program)
Maxime Jean (PhD/MD student, thesis, currently a Resident at the University of Rochester Medical Center)
Sydney Simpson (PhD student, currently a PhD candidate at the University of Rochester Medical Center)
Michael Dieringer (undergrad student, currently a medical student at SUNY Downstate College of Medicine)
Nick Osborne (Research intern, currently a medical student at Noetheast Ohio Medical University)
Staffs:
Derek Power (currently at the University of Rochester Medical Center)