A newly-opened, NIH-funded postdoctoral fellow position is immediately available in the laboratory of Jian Zhu at the Department of Pathology of Ohio State University Medical Center. The general interest of the lab is to investigate the epigenetic and epitranscriptional aspects in regulating viral infections and antiviral immune responses, particularly for HIV, herpesviruses, and respiratory viruses (Flu, SARS-CoV-2). The lab has the expertise in identification of novel host/viral regulators of these processes by using modern functional genomic (CRISPR/Cas9), quantitative proteomic, and other multi-omics approaches. The lab also employs a variety of “state-of-art” next-generation sequencing (NGS) technologies to determine the profound host-virus interactions. The molecular functions of newly identified host/viral factors will be further explored using virological, biochemical, molecular and cellular approaches in cell culture as well as in the animal models of viral infections. Antiviral reagents and/or immune modulators targeting these host/viral factors will be further developed as new therapeutic reagents. Specific areas of research interests include: viral infections and antiviral immune responses; epigenetic and epitranscriptional regulation of host-virus interactions; chemical inhibition of epigenetic and epitranscriptional regulators; systematic biology approaches for gene discovery; AIDS associated malignancies and pathogenesis.

Please refer to the recent publications in the lab for details:

https://www.ncbi.nlm.nih.gov/sites/myncbi/jian.zhu.2/bibliography/43887400/public/?sort=date&direction=descending

Ohio State University is a national leader in NIH research funding and offers outstanding infrastructure, state of the art core facilities, and a highly collaborative research environment for studies immunology and infectious diseases. Collaborations among basic science disciplines and between basic and clinical faculty are stimulated by multidisciplinary centers at OSU: the Infectious Disease Institute, the Center for Retrovirus Research, the Center of Microbiome Science, and the newly NIH-funded STOP-COVID Center.

The qualifications required for this position include: Ph.D. in Virology, Immunology, Microbiology, Genetics, or a related field; independent and self-motivated to manage the project; possessing necessary experimental skills and being productive; able to work with colleagues closely as a teammate.

Interested applicants may send their resume and three names of references to Dr. Zhu by email: Jian.Zhu@osumc.edu.