ANNOVAR consequence rank

The higher the rank, the severer the consequence:

  1. stopgain

  2. splicing

  3. stoploss

  4. frameshift

  5. nonframeshift

  6. nonsynonymous

  7. synonymous

  8. exonic

  9. UTR5

  10. UTR3

  11. ncRNA_splicing

  12. ncRNA_exonic

  13. upstream

  14. intronic

  15. ncRNA_intronic

  16. downstream

  17. intergenic

  18. unknown