Publications: 2021-

272. Qiuxin Zhang, Weiyi Tan, Zhiyu Liu, Yichi Zhang Wei-Shao Wei, Seth Fraden, and Bing Xu* Unnatural Peptide Assemblies Rapidly Deplete Cholesterol and Potently Inhibit Cancer Cells Journal of the American Chemical Society, 2024, 146, 12901-12906. 

271. Jiaqi Guo, Annabelle Chang, and Bing Xu* "Auto-Cleaving Bond for Better Drugs" ChemMedChem, 2024, in press. 

270. Meihui Yi, Gabriel Ashton-Rickardt, Weiyi Tan, Zhiyu Liu, Hongjian He, Jer-Tsong Hsieh, Bing Xu* "Accelerating Cellular Uptake with Unnatural Amino Acid for Inhibiting Immunosuppressive Cancer Cells" Chemistry A European. J., 2024, in press. 

269. Yuchen Qiao, Grace Wu, Zhiyu Liu, Hongjian He, Weiyi Tan, Bing Xu* "Assessment of the Enzymatic Dephosphorylation Kinetics in the Assemblies of a Phosphopentapeptide that Forms Intranuclear Nanoribbons" Biomacromolecules, 2024, 25, 1310-1318. 

268. Zhiyu Liu, Jiaqi Guo, Yuchen Qiao, and Bing Xu* “Enzyme-Instructed Intracellular Peptide Assemblies" Accounts of Chemical Research, 2023, 56, 3076-3088. 

267. Jiaqi Guo, Weiyi Tan, Hongjian He, and Bing Xu* “Autohydrolysis of Diglycine Activated Succinic Esters Boosts Cellular Uptake” Angewante Chemie International Edition, 2023, 62, e202308022. 

266. Meihui Yi, Zhaoqianqi Feng, Hongjian He, Daniela M. Dinulescu, and Bing Xu* “Evaluating Alkaline Phosphatase-Instructed Self-Assembly of D-Peptides for Selectively Inhibiting Ovarian Cancer Cells” Journal of Medicinal Chem 2023, 66, 10027-10035 

265. Yuchen Qiao, and Bing Xu* “Peptide Assemblies for Cancer Therapy” ChemMedChem 2023, 18,  e20230258.

264. Jiaqi Guo, Fengbin Wang*, Yimeng Huang, Hongjian He, Weiyi Tan, Meihui Yi, Edward H. Egelman*, and Bing Xu* “Cell Spheroid Creation by Transcytotic Intercellular Gelation” Nature Nanotechnology, 2023, 18, 1094-1104.

263. Jiaqi Guo, Shane T. Rich-New, Chen Liu, Yimeng Huang, Weiyi Tan, Hongjian He, Meihui Yi, Xixiang Zhang, Edward H. Egelman*, Fengbin Wang*, and Bing Xu* Hierarchical Assembly of Intrinsically Disordered Short Peptides” Chem 2023, 9, 2530-2546. 

262. Adrianna N. Shy, Jiashu Xu, Beom Jin Kim, and Bing Xu* “An Exploration of Multiple Component Peptide Assemblies by Enzyme-Instructed Self-Assembly” ChemSystemChem, 2023, 1, e202200041 

261. Shuang Liu, Qiuxin Zhang, Hongjian He, Meihui Yi, Weiyi Tan, Jiaqi Guo, and Bing Xu* “Intranuclear Nanoribbons for Selective Killing of Osteosarcoma Cells” Angewandte Chemie International Edition, 2022, 61, e202210568.

260. Meihui Yi, Fengbin Wang, Weiyi Tan, Jer-Tsong Hsieh*, Edward H. Egelman*, and Bing Xu* “Enzyme Responsive Rigid-Rod Aromatics Target “Undruggable” Phosphatases to Kill Cancer Cells in Mimetic Bone Microenvironment” Journal of the American Chemical Society 2022, 144, 13055-13059.

259. Weiyi Tan, Qiuxin Zhang, Monica C Quiñones-Frías, Alan Hsu, Yichi Zhang, Avital Rodal, Pengyu Hong, Hongbo Luo, Bing Xu* “Enzyme Responsive Peptide Thioesters for Targeting Golgi Apparatus “, Journal of the American Chemical Society 2022, 144, 6709-6713. 

258. Qiuxin Zhang, Weiyi Tan, and Bing Xu* “Enzymatic Noncovalent Synthesis for Targeting Subcellular Organelles” ChemPlusChem, 2022, 87, e202200060.

257. Weiyi Tan, Qiuxin Zhang, Pengyu Hong*, Bing Xu* “A Self-Assembling Probe for Imaging the States of Golgi Apparatus in Live Single Cells”, Bioconjugate Chemistry, 2022, 33, 1983-1988.. 

256. Qiuxin Zhang, Weiyi Tan, Bing Xu*Synthesis and Bioactivity of Pyrrole-Conjugated PhosphopeptidesBeilstein Journal of Organic Chemistry, 2022, 18, 159-166.

255. Meihui Yi, Weiyi Tan, Jiaqi Guo, Bing Xu* “Enzymatic noncovalent synthesis of peptide assemblies generates multimolecular crowding in cells for biomedical applications” Chemical Communications, 2021, 57, 12870-12879.

254. Shuang Liu, Qiuxin Zhang, Adrianna N. Shy, Meihui Yi, Hongjian He, Shijiang Lu, Bing Xu*Enzymatically Forming Intranuclear Peptide Assemblies for Selectively Killing Human Induced Pluripotent Stem Cells (iPSCs)” Journal of the American Chemical Society 2021, 143, 15852-15862. 

253. Meihui Yi, Jiaqi Guo, Hongjian He, Weiyi Tan, Nya Harmon, Kesete Ghebreyessus, Bing Xu* “Phosphobisaromatic motifs enable rapid enzymatic self-assembly and hydrogelation of short peptidesSoft Matter 2021, 17, 8590 - 8594.

252. Hongjian He; Jiaqi Guo; Bing Xu* “Enzymatic Delivery of Magnetic Nanoparticles into Mitochondria of Live Cells” ChemNanoMat, 2021, 7, 1104-1107.

251. Weiyi Tan, Qiuxin Zhang, Jiaqing Wang, Meihui Yi, Hongjian He, and Bing Xu* “Enzymatic Assemblies of Thiophosphopeptides Instantly Target Golgi Apparatus and Selectively Kill Cancer Cells” Angewandte Chemie International Edition, 2021, 60, 12796-12801.

250. Hongjian He; Jiaqi Guo; Jiashu Xu; JIaqing Wang; Shuang Liu; Bing Xu* “The Dynamic Continuum of Nanoscale Peptide Assemblies Facilitates Endocytosis and Endosomal Escape” Nano Letters, 2021, 9, 4878-4085.

249. Dongsik Yang, Hongjian He, Beom Jin Kim, Bing Xu*Peptide Assemblies Mimicking Chaperones for Protein TraffickingBioconjugate Chemistry, 2021, 32, 502-506.

248. Jingyu Wang,* Hui Li, and Bing Xu* “Biological functions of supramolecular assemblies of small molecules in cellular environment” RSC Chemical Biology, 2021, 2, 289-305.

247.Adrianna N. Shy, Huaimin Wang, Zhaoqianqi Feng and Bing Xu* “Heterotypic Supramolecular Hydrogels Formed by Noncovalent Interactions in Inflammasomes” Molecules, 2021, 26, 77.

246. Dongsik Yang, Beom Jin Kim, Hongjian He, and Bing Xu* "Enzymatically Forming Cell Compatible Supramolecular Assemblies of Tryptophan-Rich Short Peptides" Peptide Science. 2021, 113, e24173.