PhD Students
Lizzie, whose main supervisor is Nia Bryant, studies the GLUT4 glucose transporter that is central to blood glucose homeostasis. Her focus is on analyzing the structure and function of GLUT4's N-glycan, particularly investigating how this influences the transporter's trafficking to the cell surface.
Ben joined us in 2019 from Exeter. In his PhD (co-supervised by Jamie Wood and Jane Thomas-Oates) he is continuing Peter Fisher's exciting computational modelling work, and takes it into the world of biologics in collaboration with GSK.
Harold is computational structural biology PhD student working on developing software tools for building and verifying glycan models being built into electron density maps for glycoproteins. His primary supervisor is Jon Agirre in YSBL, a part of Department of Chemistry.
Simeon, whose main supervisor is Jane Thomas-Oates, is developing O-glycan analysis methods for studying biologics. His PhD is co-sponsored by Labcorp Drug Development.
Rory is a PhD student studying bacterial oligosaccharide transporters for improved production of prebiotics. He is co-supervised by Gavin Thomas with the project working in collaboration with the industrial partner Glycom.
Josie is continuing the adaption of the N-glycosylation computational modelling to biologics in collaboration with Fujifilm diosynth Biotechnologies. Her PhD is co-supervised by Nia Bryant.
Sanjana is working on synthesis of thermally responsive polymer coated superparamagnetic iron oxide nanoparticles. The polymer undergoes phase transition above body temperature which allows it to encapsulate and release bioactive proteins which induces stem cell differentiation. Her PhD is co-supervised by Paul Genever.
PostDocs
Dave, supported by a Prosperity Partnership grant run collaboratively with Nia Bryant and Bob White, is interested in improving the production of mAbs in CHO cells by investigating aspects of cell viability.
Group Leader
Dani is a biochemist by training and has contributed to our understanding of the Golgi by purifying the COG complex while he was a postdoc with Gerry Waters in Princeton. A second postdoctoral stint with Fred Hughson in Princeton allowed Dani insight into the structural biology and biochemistry of membrane tethering and fusion. He also has extensive experience with membrane proteins through his PhD training with Hartmut Michel at the MPI of Biophysics.
Alumni
2012 - Now analytical scientist at Malaysian Healthcare Agency
2012 - Now science writer at Roche
2015 - Now postdoc at UCL
2018 - Now postdoc in Glasgow
2018 - Now grants administrator at Worldwide Cancer Research in Edinburgh
2022 - Now Assay Development Scientist at Labcorp
2009-2011
2007 - 2009
2017 - 2020 - Now scientist at Abzena
2020 - 2022 - Now a senior assay development scientist at Aptamer Group
2018-2021 - Now a science writer
2013 - 2014
2009 - 2012
2009-2010
2008 - 2009
We always welcome the interest of young researchers who would like to apply for fellowships or scholarships to pursue research questions in the areas of Golgi biology and glycan biosynthesis. Email me with your ideas and some information on your background.