Ungar lab

Our group is interested in the organisation and the function of the Golgi apparatus. This beautiful organelle is responsible for most of the post-translational modification of the proteins destined for the outside of the cell. Our philosophy is to use the methods most appropriate for the biological question rather than to tailor the question to the method. We are mostly using biochemical and cell biological methods to investigate how transport within the Golgi influences its role in post-translational modifications, but have also used genetic and physiological methods in the past. Our more recent adventures are into the realm of computational modelling in order to link the organization of biosynthetic enzymes in the Golgi with the cell's glycan profile.