Experts in HLH

Unfortunately, few physicians are knowledgeable about HLH, and it is often misdiagnosed or diagnosed too late. Without access to effective treatment, primarily bone marrow transplantation (BMT), most patients with HLH die.

As the most experienced facility in the nation in treating HLH, Cincinnati Children’s has assembled a team of researchers, physicians, families who have faced an HLH diagnosis and philanthropists to create the HLH Center of Excellence.

The center focuses on four core priorities:

• Diagnosis and clinical care

• Research

• Education and awareness

• Family support

​While HLH is rare, Cincinnati Children’s treats a large population of children with HLH. The clinical and research pioneers at Cincinnati Children’s are committed to changing the outcome for children with HLH.

Recent Research News

Discovery through innovative research is essential to developing the medical breakthroughs that improve outcomes for children with HLH.

​Currently, Cincinnati Children's is conducting many research studies that could change the face of diagnosis and care for HLH. We are conducting two HLH research studies, one focusing on a new drug to control the disease and another on a treatment regimen combining two previous approaches to treat patients with HLH. Also, read about a presentation by Michael B. Jordan, MD, about the NI-0501 trial at the ASH Annual Meeting and Exposition in December 2015.