Recent Publications

"Type I Interferon Response Is Mediated by NLRX1-cGAS-STING Signaling in Brain Injury."

Fritsch LE, Ju J, Gudenschwager Basso EK, Soliman E, Paul S, Chen J, Kaloss AM, Kowalski EA, Tuhy TC, Somaiya RD, Wang X, Allen

IC, Theus MH, Pickrell AM*

Front Mol Neurosci. 2022 Feb 25;15:852243.

“Hidden Phenotypes of PINK1/Parkin KO mice”

Paul, S., Pickrell, A.M.*

Biochimica et Biophysica Acta 2021 Jun;1865(6):129871. doi: 10.1016/j.bbagen.2021.129871.

“Selective autophagic clearance of protein aggregates is mediated by the autophagy receptor, TAX1BP1”

Sarraf, S.A., Shah, H.V., Kanfer, G., Pickrell, A.M., Ward, M.E., and Youle, R.J.

Molecular Cell 2020. Dec 3;80(5):779-795.e10. doi: 10.1016/j.molcel.2020.10.041.

“Peripheral loss of EphA4 ameliorates TBI-induced neuroinflammation and tissue damage.”

Kowalski, E.A.*, Chen, J*, Hazy, A., Fritsch, L.E. Basso, E.K.G., Chen, M., Wang, X., Qian, Y., Zhou, M., Byerly, M., Pickrell, A.M., Matson, J.B., Allen, I.C., and Theus, M.H.

J Neuroinflammation. 2019. Nov 11;16(1):210. doi: 10.1186/s12974-019-1605-2.

“PINK1/Parkin Influences Cell Cycle by Sequestering TBK1 at Damaged Mitochondria, Inhibiting Mitosis.”

Sarraf, S.A.^#, Sideris, D.P.^#, Giagtzoglou, N., Ni, L., Kankel, M.W., Sen, A., Bochicchio, L.E., Huang, CH., Nussenzweig, S.C., Worley, S.H., Morton, P.D., Artavanis-Tsakonas, S., Youle, R.J., and Pickrell, A.M.*

Cell Reports. 2019. Oct 1;29(1):225-235.e5. doi: 10.1016/j.celrep.2019.08.085.

“EGR1 Recruits TET1 to Shape the Brain Methylome during Development and upon Neuronal Activity.”

Sun, Z., Xu, X., He, J., Murray, A., Sun, M., Wei, X., Wang, X., McCoig, E., Xie, E., Xi, J., Li, L., Zhu, J., Chen, J., Morozov, A., Pickrell, A.M., Theus, M.H. and Xie, H.

Nature Communications. 2019. Aug 29;10(1):3892. doi: 10.1038/s41467-019-11905-3.

“Oxidative metabolism alterations in the emotional brain of anxiety-prone rats.”

McCoy, C.R., Sabbagh, M.N., Huaman, J.P., Pickrell, A.M., and Clinton, S.M.

Prog Neuropsychopharmacol Biol Psychiatry. 2019. Dec 20;95:109706. doi: 10.1016/j.pnpbp.2019.109706.

“Ubiquitin and Receptor Dependent Mitophagy Pathways and Their Implication in Neurodegeneration”

Fritsch, L.E., Sarraf, S.A., Moore, M.E., and Pickrell, A.M.^*

J Molecular Biology 2019 Nov 2. pii: S0022-2836(19)30611-4. doi: 10.1016/j.jmb.2019.10.015.

“Methods to Detect Mitophagy in Neurons During Disease.”

Carter, F.E., Moore, M.E., and Pickrell, A.M. ^*

J. Neurosci. Methods. 2019 1;325:108351.