Representative Publications (*Corresponding author, #Co-first author):
Chung K.K.#, Law K.C. #, Zhao Z. #, Zhan X., Ma J., Chiang C.H., Leung KH, Shrestha R., Wu Y, Li C, Lee K.M., Feng L, Li X, Wong K.B., Gao C, Xu S and Zhuang, X. * (2025). Biomolecular condensation organizes the site of autophagosome formation in plant cells. BioRxiv. https://doi.org/10.1101/2024.09.09.611939
Ma J. #, Li C.#, Ren K., Zhang K., Feng L., Law K.C., Chung K.K., Bing Y., Gao C, Kang B-H and Zhuang, X. * (2025). Plant-specific mitochondrial fission machinery connects mitochondrial dynamics and mitophagosome formation for piecemeal mitophagy. Proc Natl Acad Sci U S A. e2504921122 https://doi.org/10.1073/pnas.2504921122
Wu, Y., Xu, R., and Zhuang, X. * (2025). Multifaceted Roles of the ATG8 Protein Family in Plant Autophagy: From Autophagosome Biogenesis to Cargo Recognition. Journal of Molecular Biology 437, 168981.
Li X#, Liao J#, Chung K.K.#, Feng L, Liao Y, Yang Z, Liu C, Zhou J, Shen S, Li H, Yang C, Zhuang X, Gao C. (2024) Stress Granules Sequester Autophagy Proteins to Facilitate Plant Recovery from Heat Stress. Nature Communication. 15, 10910.
Isono, E., Li, J., Pulido, P., Siao, W., Spoel, S.H., Wang, Z., Zhuang, X., and Trujillo, M. (2024). Protein degrons and degradation: Exploring substrate recognition and pathway selection in plants. Plant Cell 36, 3074-3098.
D. Liu, C. Lopez-Paz, Y. Li, X. Zhuang, J. Umen*. (2024). Subscaling of a cytosolic RNA binding protein governs cell size homeostasis in the multiple fission alga Chlamydomonas. PLOS Genetics 20, e1010503.
Zhuang X. #*, Li B. #*, and Jiang L. #* (2024). Autophagosome biogenesis and organelle homeostasis in plant cells. Plant Cell. 36, 1312-1333.
Zhuang X. #*, Li R. #*, and Jiang L. #* (2024). A Century Journey of Organelles Research in the Plant Endomembrane System. Plant Cell. 36, 3009-3024.
Luo M#, Law KC#, He Y#, Chung KK, Po MK, Feng L, Chung KP, Gao C, Zhuang, X. * and Jiang L.* (2023) Arabidopsis AUTOPHAGY-RELATED (ATG) 2 is essential for ATG18a and ATG9 trafficking during autophagosome closure. Plant Physiology. 193(1), 304-321.
Zhou, J., Ma, J., Yang, C., Zhu, X., Li, J., Zheng, X., Li, X., Chen, S., Feng, L., Wang, P., Ho, M. I., Ma, W., Liao, J., Li, F., Wang, C., Zhuang, X., Jiang, L., Kang, B. H., & Gao, C. (2023). A non-canonical role of ATG8 in Golgi recovery from heat stress in plants. Nature Plants, 9(5), 749-765.
Sun S, Feng L, Chung KP, Lee KM, Cheung HHY, Luo M, Ren K, Law KC, Jiang L, Wong KB, Zhuang X. * (2021) Mechanistic insights into an atypical interaction between ATG8 and SH3P2 in Arabidopsis thaliana. Autophagy 18, 1350-1366.
Zhuang, X. *, Chung, K.P. #, Luo Mengqian and Jiang, L*. (2018) Autophagosome Biogenesis and the Endoplasmic Reticulum: A plant perspective. Trends in Plant Science 23:677-692
Zhuang, X., Chung, K.P. and Jiang, L. (2017) Targeting tail-anchored proteins into plant organelles. Proc Natl Acad Sci U S A 114:1762-1764.
Zhuang, X. #, Chung, K.P. #, Cui, Y. #, Lin, W., Gao, C., Kang, Y.B., and Jiang, L. (2017) ATG9 Regulates Autophagosome Progression from the Endoplasmic Reticulum in Arabidopsis. Proc Natl Acad Sci U S A 114: E426-E43
Zhuang X. #, Cui, Y. #, Gao, C., and Jiang, L. (2015). Endocytic and autophagic pathways crosstalk in plants. Current Opinion in Plant Biology 28, 39-47.
Zhuang X. #, Wang, H. #, Lam, S.K., Gao, C., Wang, X., Cai, Y., and Jiang, L. (2013). A BAR-domain protein SH3P2, which binds to phosphatidylinositol 3-phosphate and ATG8, regulates autophagosome formation in Arabidopsis. Plant Cell 25, 4596-4615.