SELECTED Publications since 2022

5. Afandizada Y, Abeywansha T, Guerineau V, Sargueil B, Zhang Y, Ponchon L#, Iannazzo L#, Quelquejeu M#. Copper catalyzed cycloaddition for the synthesis of non isomerisable 2’ and 3’-regioisomers of arg-tRNAarg. Methods (2024).

4. Becht DC*, Mohid SA*, Lee JE*, Zandian M*, Benz C, Sinha VK, Ivarsson Y, Ge K, Zhang Y#, Kutateladze TG#. MLL4 binds TET3. Structure (2024) 32, 706–714.e1–e3

3. Abeywansha T*, Huang W*, Ye X, Nawrocki A, Lan X, Jankowsky E, Taylor DJ#, Zhang Y#. The structural basis of tRNA recognition by arginyl-tRNA-protein transferase. Nat Commun 14, 2232 (2023).

2. Penumutchu S*, Liu J*, Singh UK*, Kutateladze TG, Zhang Y. Protocol to identify drug-binding sites in proteins using solution NMR spectroscopy. STAR protocols. 2022; 3 (4), 101842

1. Zhang Y#, Towers CG, Singh UK, Liu J, Hakansson M, Logan DT, Donini O#, Kutateladze TG#. Dusquetide modulates innate immune response through binding to p62. Structure. 2022; 30 (8), 1055-1061. e7

Selected Publications before 2021

1. Zhang Y, Brown K, Yu Y, Ibrahim Z, Zandian M, Xuan H, Ingersoll S, Lee T, Ebmeier CC, Liu J, Panne D, Shi X, Ren X, Kutateladze TG. Nuclear Condensates of p300 formed though the structured catalytic core can act as a storage pool of p300 with reduced HAT activity. Nat Commun. 2021 07 29; 12(1):4618.

2. Zhang Y#, Narlikar GJ#, Kutateladze TG#. Enzymatic reactions inside biological condensates. J Mol Biol. 2020 Aug 14. PMID: 32805219. (invited review)

3. Zhang Y, Guo Y, Gough SM, Zhang J, Vann KR, Li K, Cai L, Shi X, Aplan PD, Wang GG, Kutateladze TG. Mechanistic insights into chromatin targeting by leukemic NUP98-PHF23 fusion. Nat Commun. 2020 Jul 03; 11(1):3339. PMID: 32620764.

4. Zhang Y, Bertulat B, Tencer AH, Ren X, Wright GM, Black J, Cardoso MC, Kutateladze TG. MORC3 Forms Nuclear Condensates through Phase Separation. iScience.  2019 Jul 26; 17:182-189. PMID: 31284181.

5. Zhang Y*, Jang Y*, Lee JE, Ahn JW, Xu L, Holden MR, Cornett EM, Krajewski K, Klein BJ, Wang SP, Dou Y, Roeder RG, Strahl BD, Rothbart SB, Shi X, Ge K, Kutateladze TG. Selective binding of the PHD6 finger of MLL4 to histone H4K16ac links MLL4 and MOF. Nat Commun. 2019 05 24; 10(1):2314. PMID: 31127101.

6. Zhang Y, Klein BJ, Cox KL, Bertulat B, Tencer AH, Holden MR, Wright GM, Black J, Cardoso MC, Poirier MG, Kutateladze TG. Mechanism for autoinhibition and activation of the MORC3 ATPase. Proc Natl Acad Sci U S A. 2019 03 26; 116(13):6111-6119. PMID: 30850548.

7. Zhang Y*, Mi W*, Xue Y*, Shi X, Kutateladze TG. The ZZ domain as a new epigenetic reader and a degradation signal sensor. Crit Rev Biochem Mol Biol. 2019 Feb; 54(1):1-10. PMID: 30691308. (Review)

8. Zhang Y, Mun SR, Linares JF, Ahn J, Towers CG, Ji CH, Fitzwalter BE, Holden MR, Mi W, Shi X, Moscat J, Thorburn A, Diaz-Meco MT, Kwon YT, Kutateladze TG. ZZ-dependent regulation of p62/SQSTM1 in autophagy. Nat Commun. 2018 10 22; 9(1):4373. PMID: 30349045.

9. Mi W*, Zhang Y*, Lyu J*, Wang X, Tong Q, Peng D, Xue Y, Tencer AH, Wen H, Li W, Kutateladze TG, Shi X. The ZZ-type zinc finger of ZZZ3 modulates the ATAC complex-mediated histone acetylation and gene activation. Nat Commun. 2018 09 14; 9(1):3759. PMID: 30217978.

10. Zhang Y*, Xue Y*, Shi J, Ahn J, Mi W, Ali M, Wang X, Klein BJ, Wen H, Li W, Shi X, Kutateladze TG. The ZZ domain of p300 mediates specificity of the adjacent HAT domain for histone H3. Nat Struct Mol Biol. 2018 09; 25(9):841-849. PMID: 30150647.

Selected Publications (Commentary)

1. Zhang Y, Kutateladze TG. Molecular structure analyses suggest strategies to therapeutically target SARS-CoV-2. Nat Commun. 2020 06 10; 11(1):2920. PMID: 32523109.  

2. Zhang Y, Kutateladze TG. Exploring epigenetics with chemical tools. Nat Chem. 2020 May 29. PMID: 32472102.

3. Zhang Y, Kutateladze TG. Liquid-liquid phase separation is an intrinsic physicochemical property of chromatin. Nat Struct Mol Biol. 2019 Dec; 26(12):1085-1086. PMID: 31695191. 

4. Zhang Y, Mun SR, Linares JF, Towers CG, Thorburn A, Diaz-Meco MT, Kwon YT, Kutateladze TG. Mechanistic insight into the regulation of SQSTM1/p62. Autophagy. 2019 Apr; 15(4):735-737. PMID: 30653391.

5. Zhang Y, Kutateladze TG. Diet and the epigenome. Nat Commun. 2018 08 28; 9(1):3375. PMID: 30154441.