The Core Concept: Hypoxia as a Root Cause
In this framework, chronic hypoxia (low oxygen levels in tissues) is viewed as the "silent killer" that precedes formal medical diagnoses. The theory suggests that when cells don't receive enough oxygen, they cannot produce energy efficiently through aerobic respiration.
How Hypoxia Leads to Disease
According to this theory, the body undergoes several stages of adaptation when oxygen is low:
Metabolic Shift: Cells switch to anaerobic metabolism (fermentation), which produces less energy and more acidic waste (lactic acid).
Inflammation & Survival: To survive in a low-oxygen environment, cells may trigger inflammatory responses or, in the case of cancer, undergo mutations to survive without oxygen.
Vascular Stress: The body may tighten blood vessels to increase pressure (leading to Hypertension) or grow new, weak blood vessels to find oxygen.
Organ Decline: Over time, the lack of energy causes organs to malfunction, leading to the "Hypoxia-type" versions of the diseases listed in the table (e.g., Renal Failure or Dementia).
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