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Yunxiang Huang (黄云翔)
Thayer School of Engineering, Dartmouth College, Hanover, NH 03755 USA
Email: Yunxiang.Huang@dartmouth.edu
Research Experiences:
Postdoc, Dartmouth College, USA, 2022.04-present
Postdoc, Tsinghua University, China, 2018.01-2022.03
PhD, South China University of Technology, China, 2013.09-2017.12
Research Interest: I am developing non-genetic bio-interfaces using innovative materials, devices and strategies to modulate and sense neural activities in vitro and vivo, advancing neuroscience research, healthcare, and clinical applications.
Skills and Expertise: Semiconductor processing, Bio-device microfabrication, Bio-optoelectronics, Neural modulation and sensing, Implantation-related protocols
Publications
X. Cheng, W. Li, Y. Wang, K. Weng*, Y. Xing, Y. Huang. X. Sheng, J. Yao*, H. Zhang*, J. Li*, "Highly Branched Au Superparticles as Efficient Photothermal Transducers for Optical Neuromodulation", ACS Nano (2024). Link
Y. Huang#, G. Li#, T. Bai, Y. Shin, X. Wang, A. More, P. Boucher, C. Chandrasekaran, J. Liu, H. Fang*, "Flexible electronic-photonic 3D integration from ultrathin polymer chiplets", npj Flexible Electronics 8, 61 (2024). Link
Highlight: 3D integration strategies of creating a bio-safe, low-noise and artifact-free neural optrode with high-density recording electrode and micro-LED arrays for optogenetic recording and stimulation.
Y. Shin, J. Ryu, T. Bai, Y. Qiang, Y. Qi, G. Li, Y. Huang, K. J. Seo*, H. Fang*, "Array-wide Uniform PEDOT:PSS Electroplating from Potentiostatic Deposition", Biosensors and Bioelectronics 261, 116418 (2024) (Invited). Link
Highlight: Processing of a large-area microelectrode array (MEA) with robust uniformity and impedance for precise neuronal spike detection.
X. Fu#, Z. Hu#, W. Li, L. Ma, J. Chen, M, Liu, J. Liu, S. Hu, H. Wang, Y. Huang, G. Tang, B. Zhang, X. Cai, Y. Wang, L. Li, J. Ma, S.-H. Shi, L. Yin, H. Zhang, X. Li*, X. Sheng*, "A Silicon Diode-based Optoelectronic Interface for Bidirectional Neural Modulation", Proceedings of the National Academy of Sciences 121, e2404164121 (2024). Link
Highlight: Neural excitation or inhibition with high-power & short-pulsed or low-power & long-pulsed optical modulation strategies, using monolithic thin-film Si-based optoelectronic diode.
P. Sun#, C. Li#, C. Yang#, M. Sun, H. Hou, Y. Guan, J. Chen, S. Liu, K. Chen, Y. Ma, Y. Huang, X. Li, H. Wang, L. Wang, S. Chen, H. Cheng, W. Xiong, X. Sheng, M. Zhang, J. Peng, S. Wang*, Y. Wang*, L. Yin*, "A Biodegradable and Flexible Neural Interface for Transdermal Optoelectronic Modulation and Regeneration of Peripheral Nerves", Nature Communications 15, 4721 (2024). Link
Highlight: Enhanced thin-film Si-based optoelectronic interfaces for tether-free transdermal peripheral neuromodulation.
H. Wang, J. Tian, Y. Jiang, S. Liu, J. Zheng, N. Li, G. Wang, F. Dong, J. Chen, Y. Xie, Y. Huang, X. Cai, X. Wang, W. Xiong, H. Qi, L. Yin, Y. Wang*, X. Sheng*, "A 3D Biomimetic Optoelectronic Scaffold Repairs Cranial Defects", Science Advances 9, abq7750 (2023). Link
Highlight: Non-pharmaceutical optoelectronic bio-regeneration for bone tissue defects, using a 3D biodegradable Si-based bio-scaffold.
P. Sun, Y. Guan, C. Yang, H. Hou, S. Liu, B. Yang, X. Li, S. Chen, L. Wang, H. Wang, Y. Huang, X. Sheng, J. Peng, W. Xiong, Y. Wang*, L. Yin*, “A Bioresorbable and Conductive Scaffold Integrating Silicon Membranes for Peripheral Nerve Regeneration”, Advanced Healthcare Materials 12, 2301859 (2023) Link
Highlight: Fully bioresorbable stimulators with endogenous electrical cues for enhancing the activities of Schwann cells and DRG neurons, and the nerve regeneration.
Y. Huang#, Y. Cui#, H. Deng#, J. Wang, R. Hong, S. Hu, H. Hou, Y. Dong, H. Wang, J. Chen, L. Li, Y. Xie, P. Sun, X. Fu, L. Yin, W. Xiong, S.-H. Shi, M. Luo, S. Wang*, X. Li*, X. Sheng*, "Bioresorbable Thin-Film Silicon Diodes for the Optoelectronic Excitation and Inhibition of Neural Activities", Nature Biomedical Engineering 7, 486-498 (2023) (Front Cover). Link
Highlight: Non-genetic wirelessly optical modulation on bio-electric and -calcium activities for the cultured DRG neurons, peripheral nerve, and brain cortex, using thin-film Si-based diodes.
X. Sheng*, W. Zhao, L. Li, Y. Huang, H. Ding, "Foundation of Brain-Machine Interfaces: Neurons and Diodes", Chinese Journal of Lasers 50, 0907301 (2023) (Invited) (Front Cover). 盛兴*，赵汶鑫，李丽珠，黄云翔，丁贺，脑机接口技术的基础研究：神经元与二极管，中国激光，50, 0907301 (2023). Link
H. Ding, G. Lv, Z. Shi, D. Cheng, Y. Xie, Y. Huang, L. Yin, J. Yang, Y. Wang, X. Sheng*, "Optoelectronic Sensing of Biophysical and Biochemical Signals based on Photon Recycling of a micro-LED", Nano Research 14, 3208-3213 (2021) (Invited) (Front Cover). Link
Y. Huang, Y. Tang, W. Yuan*, X. Zhang, Q. Wang, "Coupled Effect of Pre-alloying Treatment and Plasma-assisted Se Vapor Selenization Process in Cu (In, Ga) Se-2 Thin Film", Solar Energy 150, 375-382 (2017). Link
Y. Huang, Y. Tang, W. Yuan*, X. Zhang, W. Wen, Q. Wang, "Growth and Characterization of CIGS Thin Films by Plasma-assisted and Thermal-assisted Se Vapor Selenization Process", Journal of Alloys and Compounds 701, 732-739 (2017). Link
X. Zhang#, Y. Huang#, W. Yuan*, Y. Tang, "Characterization and Performance of Cu(In, Ga)Se2 Thin Films Incorporating Low Temperature Pre-annealing Process”, Journal of Alloys and Compounds 728, 29-36 (2017). Link
X. Zhang#, Y. Huang#, W. Yuan*, Y. Tang, L. Li, "Fabrication of Homogeneous CIGS Thin Film by Plasma Enhanced Se Vapor Selenization Coupled with Etching Process", Materials Letters 190, 276-279 (2017). Link
Y. Huang, Y. Tang, W. Yuan*, Q. Wang, S. Zhang, "Influence of Surface-modified Mo Back Contact on Post-selenized Cu(In, Ga) Se-2 Thin Films", Materials Science in Semiconductor Processing 57, 227-232 (2016). Link
Y. Huang#, S. Gao#, Y. Tang*, J. Ao*, W. Yuan, L. Lu, "The Multi-functional Stack Design of a Molybdenum Back Contact Prepared by Pulsed DC Magnetron Sputtering", Thin Solid Films 616, 820-827 (2016). Link
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