Cell Manufacturing Laboratory
Welcome to the Laboratory for Stem Cells, Biomaterials and Regenerative Medicine! hPSCs, including human embryonic stem cells (hESCs) and induced pluripotent stem cells (iPSCs), can be expanded indefinitely in vitro and differentiated into all the cell types of the human body. Thus, hPSC-derived cells have enormous potential in cell therapies, making artificial tissues and drug discovery.
However, many challenges should to be resolved before reaching their potential. We don’t have bioprocesses that can manufacture large # of GMP compatible cells with high purity & quality required for these applications. These cells survive, integrate and function poorly in vivo after transplantation
The Stem Cells, Biomaterials and Regenerative Medicine Laboratory aims to: (1) develop novel technology for the advanced manufacture (cost-effective, scalable, GMP compliant, high purity) of hPSCs, cells derived from hPSCs and synthetic tissues; (2) develop novel technology to significantly improve the cell survival and performance in vivo; (3) develop novel and efficient cell therapies for disease, such as parkinson's, huntington's, alzheimer's, amyotrophic lateral sclerosis, spinal cord injury, stroke, myocardial infarction and diabetes; (4) develop novel biomaterials for stem cell therapies
1-23-2018 Dr. Haishuang Lin and Mr Qiang Li's paper was selected as the top 10 paper in Biofabrication, the only one and best journal in international society of biofabrication.
Three-dimensional tissues using human pluripotent stem cell spheroids as biofabrication building blocks
Visit http://iopscience.iop.org/journal/1758-5090/page/Highlights-of-2017 to read the Highlights collection.
11-9-2017 Dr. Yuguo Lei win Nutech Emerging Innovator Award 2017