Representative Publications

• AMPK Alchemy: Therapeutic Potentials in Allergy, Aging, and Cancer. Biomol Ther, 32(2):171, 2024 

• Glutathione dynamics in the tumor microenvironment: a potential target of cancer stem cells and T cells. Int J Stem Cells, 17(3):270, 2024 

• IL-27-induced PD-L1highSca-1+ innate lymphoid cells suppress contact hypersensitivity in an IL-10-dependent manner. Exp Mol Med, 56(3):616, 2024

• Toll-like receptor 13-mediated signaling protects against the development of colon cancer. Int J Cancer, 155(10):1858, 2024 

• Prospect of ULK1 modulators in targeting regulatory T cells. Bioorg Chem, 129:106141, 2022 

• Serum and glucocorticoid-regulated kinase 1: Structure, biological functions, and its inhibitors. Front Pharmacol, 13:1036844, 2022 

• Maternal gut bacteria drive intestinal inflammation in offspring with neurodevelopmental disorders by altering the chromatin landscape of CD4+ T cells. Immunity, 55(1):145-158, 2022 

• A critical role for Th17 cell-derived TGF-β1 in regulating the stability and pathogenicity of autoimmune Th17 cells. Exp Mol Med, 53(5):993-1004, 2021 

• Type 17 immunity promotes the exhaustion of CD8+ T cells in cancer. J Immunother Cancer, 9(6):e002603, 2021 

• IL-27 confers a pro-tumorigenic activity of regulatory T cells via CD39. Proc Natl Acad Sci U S A, 116(8):3106-3111, 2019 

• Fibrinogen cleavage products and Toll-like receptor 4 promote the generation of programmed cell death 1 ligand 2-positive dendritic cells in allergic asthma. J Allergy Clin Immunol, 142(2):530-541, 2018 

• Atherogenic dyslipidemia promotes autoimmune follicular helper T cell responses via IL-27. Nat Immunol, 19(6):583-593, 2018 

• Future prospects of immune checkpoint blockade in cancer: from response prediction to overcoming resistance. Exp Mol Med, 50(8):109, 2018 

• Targeting IL-17 in autoimmunity and inflammation. Arch Pharm Res, 39(11):1537-1547, 2016 

• Tumor microenvironmental conversion of natural killer cells into myeloid-derived suppressor cells. Cancer Res 73(18):5669-5681, 2013 (selected as a ‘cover article’)