Cardiomics
Multi-variable cox-regression and ROC
(Polygenic risk score + Clinical information)
Fig 1. Receiver operator characteristic curve and AUC for conventional risk factors and combined models.
AUC, area under the curve; CAD: coronary artery disease; CI: confidence interval; PRS, polygenic risk score.
Multi-variable cox-regression and ROC
(Polygenic risk score, stratified by group)
Fig 2. Receiver operating characteristic curve and AUC for PRS stratified by age.
AUC, area under the curve; CI: confidence interval; PRS, polygenic risk score.
Survival analysis
(Polygenic risk score, prediction of subsequent clinical event)
Fig 3. Comparison of the cumulative incidence of repeat revascularization events between the upper-50% and lower-50% PRS groups.
Number at risk, the number of followed individuals; number of events, the number of individuals with repeat revascularization; PRS, polygenic risk score.