Ph.D.         Graduate Institute of Clinical Medical Science, China Medical University, Taichung, Taiwan.

M.Sc.         Graduate Institute of Transition and Leisure Education for Individuals with Disabilities, Taipei Physical Education College, Taiwan

B.Sc            Major in Biological Technology and Minor in Information Management, Fooyin University, Kaohsiung, Taiwan

8/2023 ~ present       Associate professor          Department of Exercise and Health Science, National Taipei University of Nursing and Health Sciences 

8/2020 ~ 7/2023 Assistant professor  Department of Exercise and Health Science, National Taipei University of Nursing and Health Sciences   

12/2018 ~ 8/2020 Postdoctoral Fellow  Department of Occupational Therapy; Department of Physical Therapy, Asia University 

2/2013 – 1/2018  Teaching Assistant            Department of Biochemistry, College of Medicine, China Medical University, Taichung, Taiwan

6/2012 – 6/2013          Research Assistant           Rehabilitation Department, National Taiwan University Hospital, Taipei, Taiwan

8/2008-7/2009        Research Assistant           Physical Therapy, National Cheng Kung University,Tainan, Taiwan

1/2007-7/2008       Research Assistant            Environment Medicine, National Cheng Kung University Hospital, Tainan, Taiwan 

Exercise Physiology

Cardiovascular Physiology

Cardiopulmonary Function

Aging and Health

•   2018 CMU-UCI-MDACC Joint Symposium of International Training Program-The visit of UC Irvine/MD Anderson Cancer Center

•   2017 Ministry of Science and Technology, Humanities and Social Sciences doctoral dissertation award. 

•   2017 Young Investigators Award: The 22th Annual Congress of the European College of Sport Science.

•   2015, 2016, 2017 and 2018 Ministry of Science and Technology Travel Award Grant. 

•   2015 International Student Award: The 62th Annual Meeting of the American College of Sports Medicine.

•   2015 Honorable Mention Poster Award: The 2nd Clinical and Translational Medicine Workshop.

•   Nurse license of general examination.

•   International Certificate of Active Aging Leadership-Balance and Fall Prevention. 

Archives of Physiology and Biochemistry (SCI),  Sports & Exercise Research, Aging (Albany NY),  Adaptive Medicine, Steroids, Chinese Journal of Physiology, Nutrients

Training Equipment Innovation for Reducing Blood Pressure 

1. Yi-Yuan Lin*, Yi-Hung Liao, Hua Ting, Kunanya Masodsai, Chi Chen. Effects of Somatosensory Games on Heart Rate Variability and Sleep-Related Biomarkers in Menopausal Women With Poor Sleep Quality. Innov Aging. 2024 Aug 22;8(9):igae072. GERONTOLOGY Rank 2/47 Q1. 

2. Lin, Y. Y*., Su, C. T., Liao, Y. H., & Liu, Y. C. (2023). Effects of rope skipping exercise on physical, cardiovascular fitness and exercise tolerance in adolescent students with moderate intellectual disability. Journal of intellectual disability research : JIDR, 67(11), 1136–1149. education, special Rank 1/43 Q1.

3. Yi-Yuan Lin, Shin-Yi Lee, Yu-Jung Cheng. Low-Level Laser Therapy Induces Melanoma Tumor Growth by Promoting Angiogenesis. Life (Basel). 2023 Jan 23;13(2):320. 

4. Sandhya Kresnajati*, Yi-Yuan Lin*, Toby Mündel, Jeffrey R Bernard, Hsin-Fu Lin, Yi-Hung Liao. Changes in Arterial Stiffness in Response to Various Types of Exercise Modalities: A Narrative Review on Physiological and Endothelial Senescence. Cells. 2022 Nov 9;11(22):3544 . (Q1).

5. Ching Huang, Liang-Yu Chen, Yi-Hung Liao, Kunanya Masodsai, Yi-Yuan Lin*. Effects of the Short-Foot Exercise on Foot Alignment and Muscle Hypertrophy in Flatfoot Individuals: A Meta-Analysis. Int J Environ Res Public Health. 2022 Sep 22;19(19):11994. (Q1).

6. Pei-Ying Pai#, Yi-Yuan Lin#, Shao-Hong Yu, Ching-Yuang Lin, Yi-Fan Liou, Xu-Bo Wu, James K. S. Wong, Chih-Yang Huang & Shin-Da Lee. Angiotensin II receptor blocker irbesartan attenuates sleep apnea-induced cardiac apoptosis and enhances cardiac survival and Sirtuin 1 upregulation.  Sleep Breath  . 2022 Sep;26(3):1161-1172. SCI, IF:2.816, Otorhinolaryngology (Q1).

7. Thanisorn Sinpichetkorn, Rungchai Chaunchaiyakul, Ai-Lun Yang, Yi-Yuan Lin, Kunanya Masodsai. Effects of Vinyasa Yoga on Stress and Health Benefits in Office Workers. Journal of Exercise Physiologyonline. 2022 Aug; 25(4):53-63.

8. James K. S. Wong, Cheng-Ju Wu, Yi-Yuan Lin*, Shin-Da Lee*. Acute Effects of 160-Degree V-Shape Whole-Body Periodic Acceleration (WBPA) on Blood Pressure and Cardiovascular Hemodynamics. Appl. Sci. 2022, 12(18), 9116. (Q3).

9. Pei-Ying Pai, James K S Wong, Zhen-Yang Cui, Yi-Yuan Lin*, Shin-Da Lee*. Angiotensin II Receptor Blocker Irbesartan Enhanced SIRT1 longevity Signaling Replaces the Mitochondrial Biogenetic Survival Pathway to Attenuate Hypertension-Induced Heart Apoptosis. J Cardiovasc Dev Dis. 2022 Aug 14;9(8):266. (Q2).

10. Yi Hong, Ai-Lun Yang, James K S Wong, Kunanya Masodsai, Shin-Da Lee*, Yi-Yuan Lin*. Exercise intervention prevents early aged hypertension-caused cardiac dysfunction through inhibition of cardiac fibrosis. Aging-US. 2022 May 23;14(10):4390-4401.(Q1).  

11. Wei-Long Liu#, Yi-Yuan Lin#, Toby Mündel, Chun-Chung Chou, Yi-Hung Liao. Effects of Acute Interval Exercise on Arterial Stiffness and Cardiovascular Autonomic Regulatory Responses: A Narrative Review of Potential Impacts of Aging. Front Cardiovasc Med. 2022 May 10;9:864173. (Q1).

12. Yi-Yuan Lin, Kunanya Masodsai, Ai-Lun Yang. Age-related Endothelial Cell Senescence-Implications in Hypertension. Adaptive Medicine. 2021. Sep; 13:4-7.

13. Lin-Fu Lin, Ching-Ying Tseng, Toby Mündel, Yi-Yuan Lin , Chung-Chi Lin, Chiao-Nan Chen, Yi-Hung Liao. Perturbations of Adjuvant Chemotherapy on Cardiovascular Responses and Exercise Tolerance in Patients with Early-Stage Breast Cance.  Biology (Basel). 2021 Sep 13;10(9). SCI, IF:5.079, Biology (Q1).

14. Min-Huang Hsieh, Zhen-Yang Cui, Ai-Lun Yang, Nguyen Thanh Nhu, Shih-Ying Ting, Shao-Hong Yu, Yu-Jung Cheng, Yi-Yuan Lin, Xu-Bo Wu and Shin-Da Lee*Cerebral Cortex Apoptosis in Early Aged Hypertension: Effects of Epigallocatechin-3-Gallate. Front Aging Neurosci. 2021 Aug 12;13:705304. SCI, IF:5.7, Aging (Q1); Cognitive Neuroscience (Q1).

15. Kunanya Masodsai, Yi-Yuan Lin,  Sih-Yin Lin, Chia-TingSu, Shin-Da Lee, Ai-Lun Yang *. Aging Additively Influences Insulin- and Insulin-Like Growth Factor-1-Mediated Endothelial Dysfunction and Antioxidant Deficiency in Spontaneously Hypertensive Rats. Biomedicines. 2021 Jun 15;9(6):676. SCI, IF:6.081, Biochemistry & Molecular Biology Q1.

16. Yi-Yuan Lin, Yi Hong, Ming-Cheng Zhou, Hai-Liang Huang, Woei-Cherng Shyu, Jwo-Sheng Chen, Hua Ting, Yu-Jung Cheng, Ai-Lun Yang*, Shin-Da Lee*. Exercise Training Attenuates Cardiac Inflammation and Fibrosis in Hypertensive Ovariectomized Rats. Journal of Applied Physiology, Apr 1;128(4):1033-1043. 2020. SCI, IF:3.256, Sport sci Q1.

17. Shiu-Min Cheng, Ying-Jui Ho, Shao-Hong Yu, Yi-Fan Liu, Yi-Yuan Lin, Chih-Yang Huang, Hsiu-Chung Ou, Hai-liang Huang and Shin-Da Lee*. Anti-Apoptotic Effects of Diosgenin in D-Galactose-Induced Aging Brain. The American Journal of Chinese Medicine, Mar 5:1-16. 2020. SCI, IF:3.510, Complementary and Alternative Medicine Q1.

18. Yi-Yuan Lin, Yi Hong, Shao-Hong Yu, Xu-Bo Wu, Woei-Cherng Shyu, Jwo-Sheng chen, Hua Ting, Ai-Lun Yang*, Shin-Da Lee*. Anti-apoptotic and mitochondrial biogenetic Effects of Exercise Training on Ovariectomized Hypertensive Rats heart. Journal of Applied Physiology, 126: 1661–1672. SCI, IF:3.256, Sport sci Q1.

19. Kunanya Masodsai, Yi-Yuan Lin, Rungchai Chaunchaiyakul, Chia-TingSu, Shin-Da Lee, Ai-Lun Yang *. Twelve-weeks protocatechuic acid administration improvesinsulin-induced and insulin-like growth factor 1-induced vasorelaxation andantioxidant activities in aging spontaneously hypertensive rats. Nutrients. 2019. SCI, IF:4.196, Food Science Q1.

20. Yi-Yuan Lin, Jwo-Sheng Chen, Xu-Bo Wu, Woei-Cherng Shyu, Rungchai Chaunchaiyakul, Xian-Li Zhao, Chia-Hua Kuo, Ai-Lun Yang*, and Shin-Da Lee*. Combined Effects of 17β-estradiol and Exercise Training on Cardiac Apoptosis in Ovariectomized Rats. PLOS ONE. 2018 Dec 20;13(12):e0208633. SCI, IF:2.776, Agricultural and Biological Sciences (miscellaneous) Q1.

21. Yi-Yuan Lin and Shin-Da Lee* “Cardiovascular Benefits of Exercise Training in Post-menopausal Hypertension” International Journal of Molecular Sciences. 2018, 19(9), 2523. (Review article) SCI, IF:4.183. Medicine (miscellaneous) Q1.

22. Chiu-Ching Huang, Yi-Yuan Lin, Tang-Wei Kuo, Chia-Hua Kuo, Ai-Lun Yang*, Shin-Da Lee*. “Anti-Renal Fibrotic Effect of Exercise Training in Hypertension.” International Journal of Molecular Sciences. 2018 Feb 20;19(2). pii: E613. SCI, IF:4.183. Medicine (miscellaneous) Q1.

23. Yi-Yuan Lin, Po-Shiuan Hsieh, Yu-Jung Cheng, Shiu-Min Cheng, Chiao-Nan Chen, Chih-Yang Huang, Chia-Hua Kuo, Chung-Lan Kao, Woei-Cherng Shyu*, and Shin-Da Lee*. Anti-apoptotic and Pro-survival Effects of Food Restrictionon High-Fat Diet-induced Obese Hearts. Cardiovascular Toxicology. 2017 Apr;17(2):163-174. SCI, IF:2.630, Q2.

24. Kunanya Masodsai, Yi-Yuan Lin, Shin-Da Lee, and Ai-Lun Yang*. Exercise and Endothelial Dysfunction in Hypertension. Adaptive Medicine. 2017 Mar;9(1):1-14. (Review article)

25. Yi-Yuan Lin, Yu-Jung Cheng, Jun Hu, Li-Xi Chu, Woei-Cherng Shyu, Chung-Lan Kao, Tzer-Bin Lin, Chia-Hua Kuo, Ai-Lun Yang*, and Shin-Da Lee*. The Coexistence of Hypertension and Ovariectomy Additively Increases Cardiac Apoptosis. International Journal of Molecular Sciences. 2016 Dec 6;17(12). pii: E2036. SCI, IF:4.183. Medicine (miscellaneous) Q1.

26. Chih-Yang Huang*, Yi-Yuan Lin, Chih-Chao Hsu, Shiu-Min Cheng, Woei-Cherng Shyu, Hua Ting#, Ai-Lun Yang11*, Tsung-Jung Ho1*, and Shin-Da Lee#. Antiapoptotic effect of exercise training on ovariectomized rat hearts. Journal of applied physiology. 2016, Aug 30;59(3):165-72. SCI, IF:3.256, Sport sci Q1.

27. Tsung-Lin Cheng, Yi-Yuan Lin, Chia-Ting Su, Chun-Che Hu, and Ai-Lun Yang*. Improvement of Acetylcholine-Induced Vasodilation by Acute Exercise in Ovariectomized Hypertensive Rats. The Chinese Journal of Physiology. 2016 Jun 30;59(3):165-72. SCI, IF:1.108.

28. Yi-Yuan Lin, Shin-Da Lee, Chia-Ting Su, Tsung-Lin Cheng, and Ai-Lun Yang*. Long-term treadmill training ameliorates endothelium-dependent vasorelaxation mediated by insulin and insulin-like growth factor-1 in hypertension. Journal of applied physiology. 2015 Sep 15;119(6):663-9. SCI, IF:3.256, Sport sci Q1.

29. Yi-Yuan Lin, Chia-Ting Su, Hsin-Yu Chiang, Chun-Hsin Lin, Ai-Lun Yang*. Blood Pressure, Pulmonary Function, and Exhaustive Exercise Performance in Triathletes. Sports & Exercise Research, 21(3):283-294.

1. Yi-Yuan Lin, Kunanya Masodsai, Ai-Lun Yang, Shin-Da Lee, Aerobic exercise training suppresses LOXL2 / TGF-β driven cardiac fibrotic pathway on aging hypertensive rat hearts. 2021 International exercise physiology and fitness annual conference. (Honorable Mention Poster Award)

2. Pin-Hsiu Lin, Mei-Yi Liu, Chen-Chen Chi, Yi-Yuan Lin*, Effects of exercises in switch exergames on enjoyment and fitness in middle-aged and older adults. 2021 International exercise physiology and fitness annual conference.

3. Yen-Ching Liu, Ching Huang, Yi-Yuan Lin*, The effects of rope skipping intervention on the Influence of Healthy Physical Fitness for students with mild to moderate intellectual disabilities: A integrative literature review. 2021 International exercise physiology and fitness annual conference.

4. Wen-Yu Chang, Yi-Yuan Lin*, The effects of meridian massage on heart rate variability and anxiety: A integrative literature review. 2021 International exercise physiology and fitness annual conference.

5. Yi-Yuan Lin, Ai-Lun Yang, Shin-Da Lee. Aerobic Exercise Training Suppresses TNF-a/NFkB-Driven Cardiac Inflammation and TGF-b/CTGF-Mediated Fibrosis in a Rat Model of Postmenopausal Hypertension. CMU-UCI-MDACC Joint Symposium of International Training Program, Oct, 2018, Taichung Taiwan.

6. Yi-Yuan Lin, Ai-Lun Yang, Shin-Da Lee. Anti-Fibrotic Effects of Exercise Training Combined with 17β-estradiol on Ovariectomized Rat Hearts. The 23th Annual Congress of the European College of Sport Science, July, 2018, Dublin Ireland.

7. P.H. Lee, Yi-Yuan Lin, Chia-Ting Su, Chun Hsin Lin, Ai-Lun Yang. Exploration of Blood Pressure, Arterial Stiffness, and Heart Rate Variability in Triathletes. The 23th Annual Congress of the European College of Sport Science, July, 2018, Dublin Ireland.

8. Shin-Da Lee, Yi-Yuan Lin, Shiu-Min Cheng, Chih-Yang Huang. Anti-apoptosis effects of Diosgenin in D-galactose-induced aging brains. The 65th Annual Meeting of the American College of Sports Medicine, May, 2018, Minneapolis, USA.

9. Yi-Yuan Lin, Ai-Lun Yang, Shin-Da Lee. Effect of Exercise Training on Cardiac Inflammation and Fibrosis in Hypertensive Ovariectomized Rats. The 22th Annual Congress of the European College of Sport Science, July, 2017, Essen, Germany. (2nd Young Investigators Award)

10. Yi-Yuan Lin, Ai-Lun Yang, Shin-Da Lee. Combined Effects of 17-beta-Estradiol and Exercise Training Protects Against Cardiac Apoptosis in Ovariectomized Rats. The 21th Annual Congress of the European College of Sport Science, July, 2016, Vienna, Austria.

11. Tang-Wei Kuo, Yi-Yuan Lin, Ai-Lun Yang, Shin-Da Lee. Effect of Exercise Training Prevents Renal Fibrosis in Rats with Hypertension. The 10th International Society of Physical and Rehabilitation Medicine World Congress, May, 2016, Kuala Lumpur, Malaysia.

12. Yi-Yuan Lin, Ai-Lun Yang, Shin-Da Lee. Anti-apoptotic Effects of Exercise Training on Ovariectomized Spontaneously Hypertensive Hearts. The 62th Annual Meeting of the American College of Sports Medicine, May, 2015, San Diego, USA. (International Student Award)

13. Yi-Yuan Lin, Ai-Lun Yang, Shin-Da Lee. Effect of Aerobic Exercise Training Prevents Cardiac Mitochondrial-dependent Apoptotic Pathway in Hypertensive Rats after Ovariectomy. The 2nd Clinical and Translational Medicine Workshop, Apr, 2015, Taichung, Taiwan. (Honorable Mention Poster Award)

14. Shin-Da Lee, Yi-Yuan Lin, Po-Shiuan Hsieh. Anti-apoptotic and Pro-survival Effects of Food Restriction on High-fat Diet-induced Obese Hearts. The 62th Annual Meeting of the American College of Sports Medicine, May 2015.  San Diego, USA.

15. Wen-Chia Chao, Ai-Lun Yang, Chia-Ting Su, Yi-Yuan Lin. Effects of Long-term Aerobic Exercise on Vascular Function Mediated by Insulin and Insulin-like Growth Factor-1 in Hypertension. Experimental Biology, Apr, 2012, San Diego, USA.

16. Yi-Yuan Lin, Ying-Jui Ho, Chih-Yang Huang, Shin-Da Lee. Effects of Diosgenin on Cardiac Fas Receptor-dependent Apoptosis in D-galactose-Induced Aging Rats. Traditional Chinese Medicine and Alternative (Herbal) Medicine. Sep, 2011, Taichung, Taiwan.

17. Yi-Yuan Lin, Ai-Lun Yang.  Effects of Aerobic Exercise on Vascular Endothelial Function in Postmenopausal Hypertensive Animal Model. The First Cross-Strait Symposium on Adaptive Medicine and Fitness. Sep, 2010, Taipei, Taiwan.

18. Yi-Yuan Lin, Ai-Lun Yang, Chien-Kuei Yeh, Chia-Ting Su. Vasorelaxant Responses in Aortas of Hypertensive Rats following Moderate-intensity Treadmill Exercise. The 57th Annual Meeting of the American College of Sports Medicine, June, 2010, Baltimore, USA.

1. Investigation of effects and mechanisms of exercises in switch exergames on aging cerebral circulation and cardiovascular function 2021.01~2021.12