Ying, Y., Liu, Y., Liu, S., Li, L.,, Ma, B., Yuan, L., Dou, X., Shentu, Qin., Ai, R., Lei, J., Qi, L.*, Jiang, Y.*, and Fang, X.*, Single-molecule microscopy for precision medicine and diagnostics. Trends Anal. Chem., 2026, 197, 118723.
Tong, S.#, Fu, X.#, Qi, L., Wang, H., Tang, J., Ren, D., Wang, H., Bao, Y., Yuan, L., Wang, C., Liu, S., Liu, Y., Zhou , P., Xu , Y., Ruan, J., Li, X., Jiang, Y.*, Xiao, Y.*, Fang, X.*, Separation-free extracellular vesicle microRNA Profiling using Structurally Oriented Membrane Fusion and Spatially Confined Amplification. ACS Nano, 2026, 20, 2918–2930.
Liu, S.#, Wang, H.#, Shentu, Q., Yuan, L., Tie, J., Li, L., Ai, R., Ma, B., Qi, L.*, Jiang, Y.* and Fang, X.*, Profiling of Integrin Isoforms on Lung-tropic Exosomes by Spectrally and Kinetically Multiplexed Single-molecule Imaging. Adv. Sci., 2025,10.1002/advs.202515129 （Journal Cover)
Yu, H.; Sun. Q*; Jiang, Y.*, Recent progress in carbazole-based small-molecule single-component organic room-temperature phosphorescence. J. Mater. Chem. C, 2025, 13, 22879-22898. （Journal Cover)
Yang, H.#; Yan, Z.#; Liu, X.; Liu, W.; Lin, P.; Xue, H.; Wu, Y.; Jiang, Y.*; Fan, Q.*; Wang, J.* and Fang, X.*; Single-chain ultrasmall fluorescent polymer dots enable nanometer-resolution cellular imaging and single protein tracking. Nat. Photon. 2025. 19, 1336.
Yao, X.#; Ping, J.#; Chen, L.; Qi, L.; Tang, K.; Cai, R.; Li, L.; Xiao, Y.; Qi, L.; Hu, Q.*; Fang, X.* and Jiang, Y.* Highly-emissive BODIPY-grafted polymer dots for cellular and tissular STED imaging. Precis. Chem. 2025, 3, 11, 706–714（Journal Cover, ACS editor's choice）
Wang, X.; Che, Y.; Liu, S.; Ma, B.; Liu, Y.; Lei, J.; Yuan, L.; Zhou, Y.; Ying, J.; Zhang, Y.; Tian, C.; Zhu, T.; Qi, L.*; Jiang, Y.* and Fang, X.*, Single-Molecule Liquid Biopsy Detects Low- and High-Abundance Protein Markers Simultaneously for Pancreatic Cancer Diagnosis. Anal. Chem. 2025, 97(15), 8385.
Liu, S.; Ma, B.; Qi, L.; Ping, J.; Che, Y.; Zhang, Y.; Su, M.; Song, Y.; Qi, L.*; Jiang, Y.* and Fang, X.*, Ultrasensitive Detection of Cancer Biomarkers Using Photonic-Crystal-Enhanced Single-Molecule Imaging. Anal. Chem. 2024, 96(2), 866.
Qi, L.; Liu, S.; Ping, J.; Yao, X.; Chen, L.; Yang, D.; Liu, Y.; Wang, C.; Xiao, Y.; Qi, L.*, Jiang, Y.* and Fang, X.*, Recent Advances in Fluorescent Nanoparticles for Stimulated Emission Depletion Imaging. Biosensors, 2024, 14 (7), 314.
Qi, L., Xiao, Y., Fu, X., Yang, H., Fang, L., Xu, R., Ping, J., Han, D., Jiang, Y.* and Fang, X.*, Monodispersed and Monofunctionalized DNA‐Caged Au Nano‐Clusters with Enhanced Optical Properties for STED Imaging. Small, 2024, 20(29),12400238.
Wang, F., Zhang, C., Deng, S., Jiang, Y., Zhang, P., Yang, H., Xiang, L., Lyu, Y., Cai, R.* and Tan, W., Dual-responsive 3D DNA nanomachines cascaded hybridization chain reactions for novel self-powered flexible microRNA-detecting platform. Biosens. Bioelectron. 2024, 252, 116149.
Liu, S., Guo, Y., Jiang, Y., Gong, Y., Hu, Q.* and Yu, L.*, Single-Chain Conjugated Polymer Guests Confined inside Metal–Organic Frameworks (MOFs): Boosting the Detection and Degradation of a Sulfur Mustard Simulant. Anal. Chem. 2024, 96(6), 2333.
Qi, L., Liu, J., Liu, S., Liu, Y., Xiao, Y., Zhang, Z.*, Zhou, W., Jiang, Y.*, Fang, X.* Ultra-sensitive point-of-care detection of protein markers using an aptamer-CRISPR/Cas12a-regulated liquid crystal sensor (ALICS). Anal. Chem. 2024, 96(2), 866.
Ma, B., Li, L., Bao, Y., Yuan, L., Liu, S., Qi, L., Tong, S., Xiao, Y., Qi, L., Fang, X.*, and Jiang, Y.*, Optical Imaging of Single Extracellular Vesicles: Recent Progress and Prospects. Chem. Biomed. Imaging 2024, 2(1), 27.
Xiang, S., Li, J., Wang, F., Yang, H., Jiang, Y., Zhang, P., Cai, R.* and Tan, W., Novel ultralow-potential electrochemiluminescence aptasensor for the highly sensitive detection of zearalenone using a resonance energy transfer system. Anal. Chem., 2023, 95(40), 15125.
Fang, L., Ai, R., Wang, W., Tan, L., Li, C., Wang, D., Jiang, R., Qiu, F., Qi, L., Yang, J., Zhou, W., Zhu, T., Tan, W., Jiang, Y.,* and Fang, X.* Hyperbranched Polymer Dots with Strong Absorption and High Fluorescence Quantum Yield for In Vivo NIR-II Imaging. Nano Lett. 2023, 23(18), 8734.
Jiang, Y.#*; Zhang, J.#; Jung, S.-R.; Chen, H.; Xu, S.; Chiu, D. T.*, High-Precision Mapping of Membrane Proteins on Synaptic Vesicles using Spectrally Encoded Super-Resolution Imaging. Angew. Chem. Int. Ed. 2023, 62 (8), e202217889.
Guo, Y., Wu, A., Qiu, C., Ge, F., Jiang, Y., Gong, Y.*, Hu, Q.*, Force‐Induced Molecular Isomerization for the Construction of Multicolor Luminescent Segmented Molecular Crystals. Adv. Opt. Mater. 2022, 10(2), 2101794.
Liu, X., Jiang, Y., Cui, Y., Yuan, J., Fang, X.*, Deep learning in single-molecule imaging and analysis recent advances and prospects. Chem. Sci. 2022, 13, 11964-11980.
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Zhang, J., Yu, J., Jiang, Y., Chiu, D. T.*, Ultrabright pdots with a large absorbance cross section and high quantum yield. ACS Appl. Mater. Interfaces. 2022 14(11):13631-7.
Jiang, Y.; Andronico, L.; Jung, S.-R.; Chen, H.; Fujimoto, B,; Vojtech, L.; Chiu, D. T.*, High-Throughput Flow Counting and Superresolution Mapping of Tetraspanins on Semen Exosomes using a Single-Molecule Sensitive Flow Technique and Transistor-like Semiconducting Polymer Dots. Angew. Chem. Int. Ed. 2021, 60 (24), 13470-13475. (VIP article)
Andronico, L.; Jiang, Y.; Jung, S.-R.; Fujimoto, B. S.; Vojtech, L.; Chiu, D. T.*, Sizing Extracellular Vesicles using Membrane Dyes and a Single Molecule-sensitive Flow Analyzer. Anal. Chem. 2021, 93 (14), 5897-5905.
Jiang, Y.#*; Chen. H. #, Men, X.; Sun, Z.; Yuan, Z.; Zhang, X.; Chiu, D. T.; Wu, C.*; McNeill, J.*, Multi-mode Time-resolved Superresolution Microscopy Revealing Chain Packing and Anisotropic Single Carrier Transport in Conjugated Polymer Nanowires. Nano. Lett. 2021, 21 (10), 4255-4261. （Featured as Journal Cover）
Jung, S.-R.*; Jiang, Y.; Chiu, D. T.; Hille, B.; Koh, D.-S., β-arrestin-dependent PI(4,5)P2 synthesis boosts GPCR endocytosis. Proc. Natl. Acad. Sci. U. S. A. 2021, 118 (17).
Sun, K.; Liu, S.; Liu, J.; Ding, Z.; Jiang, Y.; Zhang, J.; Chen, H.; Yu, J.; Wu, C.*; Chiu, D. T.*, Improving the Accuracy of Pdot-Based Continuous Glucose Monitoring by Using External Ratiometric Calibration. Anal. Chem. 2021, 93(4), 2359-2366.
Xu, S.; Wu, L.; Qin, Y.; Jiang, Y.; Sun, K.; Holcomb, C.; Gravett, M.; Vojtech, L.; Schiro, P.; Chiu, D. T.*, Sequential eDAR Isolation and FISH Identification of Rare Cells from Blood by Using Concentrated Peripheral Blood Mononuclear Cells. Anal. Chem. 2021, 93(6), 3196-3201.
Ping, J.; Qi, L.; Wang, Q.; Liu, S.; Jiang, Y.; Yu, L.; Lin, J.-M.*; Hu, Q.*, An integrated liquid crystal sensing device assisted by the surfactant-embedded smart hydrogel. Biosens. Bioelectron. 2021, 187, 113313.
Dou, X.; Sun, K.; Chen, H.; Jiang, Y.; Wu, L.; Mei, J.; Ding, Z.*; Xie, J.*, Nanoscale Metal-Organic Frameworks as Fluorescence Sensors for Food Safety. Antibiotics, 2021, 10 (4), 358.
Chen, H.; Yu, J.; Men, X.; Zhang, J.; Ding, Z.; Jiang, Y.; Wu, C.; Chiu, D. T.*, Reversible Ratiometric NADH Sensing Using Semiconducting Polymer Dots. Angew. Chem. Int. Ed. 2021, 133 (21), 12114-12119.
Chen, H.; Yu, J.; Zhang, J.; Sun, K.; Ding, Z.; Jiang, Y.; Hu, Q.; Wu, C.; Chiu, D. T.*, Monitoring Metabolites Using an NAD (P) H‐sensitive Polymer Dot and a Metabolite‐specific Enzyme. Angew. Chem. Int. Ed. 2021, 133 (35), 19480-19485.
Li, B.; Guo, Y.; Jiang, Y.; Lin, J.-M.; Hu, Q.*; Yu, L.*, A pendant droplet-based sensor for the detection of acetylcholinesterase and its inhibitors. Chem. Commun. 2021, 57 (71), 8909-8912.
Jiang, Y.#; Hu, Q.#; Chen, H.#; Zhang, J.; Chiu, D. T.*, McNeill, J.*, Dual-Mode Superresolution Imaging using Charge Transfer Dynamics in Semiconducting Polymer Dots Angew. Chem. Int. Ed. 2020, 59, 2–10.
Qi, L.; Liu, S.; Jiang, Y.; Lin, J.-M.; Yu, L.*; Hu, Q.*, Simultaneous Detection of Multiple Tumor Markers in Blood by Functional Liquid Crystal Sensors Assisted with Target-Induced Dissociation of Aptamer. Anal. Chem. 2020, 92 (5), 3867-3873.
Qi, L.; Hu, Q.*; Kang, Q.; Bi, Y.; Jiang, Y.; Yu, L.*, Detection of Biomarkers in Blood Using Liquid Crystals Assisted with Aptamer-Target Recognition Triggered in Situ Rolling Circle Amplification on Magnetic Beads. Anal. Chem. 2019, 91 (18), 11653-11660.
Chen, L. #; Chen, D. #; Jiang, Y.; Zhang, J.; Yu, J.; DuFort, C. C.; Hingorani, S. R.; Zhang, X.; Wu, C.*; Chiu, D. T.*, Bodipy Based Donor/Donor Acceptor System: Towards Highly Efficient Long Wavelength Excitable near-IR Polymer Dots with Narrow and Strong Absorption Features. Angew. Chem. Int. Ed. 2019, 58 (21), 7008-7012.
Jiang, Y.; McNeill, J.*, Superresolution Mapping of Energy Landscape for Single Charge Carriers in Plastic Semiconductors. Nat. Commun. 2018, 9 (1), 4314.
Jung, S.-R.#; Han, R.#; Sun, W.; Jiang, Y.; Fujimoto, B. S.; Yu, J.; Kuo, C.-T.; Rong, Y.; Zhou, X.-H.; Chiu, D. T.*, Single-Molecule Flow Platform for the Quantification of Biomolecules Attached to Single Nanoparticles. Anal. Chem. 2018, 90 (10), 6089-6095.
Jiang, Y.; Nongnual, T.; Groff, L.; McNeill, J.*, Nanoscopy of Single Charge Carrier Jumps in a Conjugated Polymer Nanoparticle. J. Phys. Chem. C, 2018, 122 (2), 1376-1383. （Featured in ACS Virtual Issue on Super-Resolution Far-Field Optical Microscopy）
Jiang, Y.; McNeill, J.*, Light-Harvesting and Amplified Energy Transfer in Conjugated Polymer Nanoparticles. Chem. Rev. 2017, 117 (2), 838–859.
Jiang, Y.; Novoa, M.; Nongnual, T.; Powell, R.; Bruce, T. F.; McNeill, J.*, Improved Superresolution Imaging Using Telegraph Noise in Organic Semiconductor Nanoparticles. Nano Lett. 2017, 17 (6), 3896–3901.
Groff, L. C.; Jiang, Y.; Wang, X.; McNeill, J.*, Effect of Swelling on Multiple Energy Transfer in Conjugated Polymer Nanoparticles. J. Phys. Chem. C, 2017, 121 (13), 7549-7557.