Publication

2022:

1.Yuan-Chin Hsieh, Jun-min Liao, Kuo-Hsiang Chuang, Kai-Wen Ho, Shih-Ting Hong, Hui-Ju Liu, Bo-Cheng Huang, I-Ju Chen, Yen-Ling Liu, Jaw-Yuan Wang, Hsiang-Lin Tsai, Yu-Cheng Su, Yen-Tseng Wang* & Tian-Lu Cheng*, A universal in silico V(D)J recombination strategy for developing humanized monoclonal antibodies. Journal of Nanobiotechnology 2022, 20 (1), 58. (doi: 10.1186/s12951-022-01259-2) (SCI, 8/159, BIOTECHNOLOGY & APPLIED MICROBIOLOGY )

2021:

1. Shih-Ting Hong , Yu-Cheng Su, Tian-Lu Cheng* and Yeng-Tseng Wang* (2021, Feb) "Anti-TNF alpha antibody Humira with pH-dependent binding characteristics: A constant-pH molecular dynamics, gaussian accelerated molecular dynamics and in vitro study", Biomolecules, 2021, 11(2), 334　(doi: 10.3390/biom11020334), (SCI, 98/297, BIOCHEMISTRY & MOLECULAR BIOLOGY)

2.Bo-Cheng Huang, Yun-Chi Lu, Jun-Min Liao, Hui-Ju Liu,Shih-Ting Hong,Yuan-Chin Hsieh,Chih-Hung Chuang ,Huei-Jen Chen,Tzu-Yi Liao, Kai-Wen Ho,Yeng-Tseng Wang* and Tian-Lu Cheng* (2021, Jun) "Development of a structure-based computational simulation to optimize the blocking efficacy of pro-antibodies", Chemical Science 2021, 12, 9759-9769 (DOI: 10.1039/D1SC01748A ) (SCI, 21/177, CHEMISTRY MULTIDISCIPLINARY )

3. Yeng-Tseng Wang* and Tian-Lu Cheng* (2021, Jul) Computational modeling of cyclic peptide inhibitor–MDM2/MDMX binding through global docking and gaussian accelerated molecular dynamics simulations, Journal of Biomolecular Structure and Dynamics, 39(11):4005-4014 (DOI:10.1080/07391102.2020.1773317)(SCI, 23/73, BIOPHYSICS)

2020:

2. Yeng-Tseng Wang* and Po-Long Wu (2020, Jul) Gene cloning, characterization, and molecular simulations of a novel recombinant chitinase from Chitinibacter tainanensis CT01 appropriate for chitin enzymatic hydrolysis, MDPI Polymers, 12(8), 1648 (doi: 10.3390/polym12081648) (SCI, 16/89, POLYMER SCIENCE )

3. Wen-Wei Lin, Yu-Jen Wang, Cheng-Wen Ko, Tain-Lu Cheng, and Yeng-Tseng Wang* (2020, Sep) "Cyclic peptide inhibitors of the Tsg101 UEV protein interactions refined through global docking and gaussian accelerated molecular dynamics simulations" , MDPI Polymers, (doi: 10.3390/polym12102235

) (SCI, 16/89, POLYMER SCIENCE )

2019:

1. Jun-min Liao and Yeng-Tseng Wang* (2019, Jan). In Silico Studies of Conformational Dynamics of Mu Opioid Receptor Performed Using Gaussian Accelerated Molecular Dynamics. Journal of Biomolecular Structure and Dynamics, 37(1), 166-177 (doi: 10.1080/07391102.2017) (SCI, 23/73, BIOPHYSICS)

2018:

1. Chih-Hung Chuang, Shean-jaw Chiou, Tian-Lu Cheng and Yeng-Tseng Wang*(2018, Apr). A molecular dynamics simulation study decodes the Zika virus NS5 methyltransferase bound to SAH and RNA analogue. A Scientific Reports , ( doi : 10.1038/s41598-018-24775-4 ). (SCI, 10/64, multidisciplinary sciences).

2017:

1. Yeng-Tseng Wang*, Yang-Hsiang Chan (2017, Aug). Understanding the molecular basis of agonist/antagonist mechanism of human mu opioid receptor through gaussian accelerated molecular dynamics method. Scientific Reports , 7(1), 7828-7833 (doi:10.1038/s41598-017-08224-2). (SCI, 10/64, multidisciplinary sciences). MOST 105-2133-M-037-000.

2. Lan CE, Wang YT, Lu CY, Fang AH, Wu CS* (2017, Jul). The effect of interaction of heat and UVB on human keratinocyte: Novel insights on UVB-induced carcinogenesis of the skin.. Journal of Dermatological Science, 88(2), 207-215. . (SCI, 7/63,Dermatology). (Lan CE and Wang YT: equal first authors)

3. Jun-min Liao*, Yeng-Tseng Wang, Chen-lung Steve Lin* (2017, Mar). A fragment-based docking simulation for investigating peptide–protein binding. Physical Chemistry Chemical Physics , 19(24),10436- 10442. (SCI, 6/35,physics, atom, molecular & chemical).

4. 1. I-Ju Chen, Chih-Hung Chuang, Yuan-Chin Hsieh, Yun-Chi Lu, Wen-Wei Lin, Chien-Chiao Huang, Ta-Chun Cheng, Yi-An Cheng, Kai-Wen Cheng, Yeng-Tseng Wang, Fang-Ming Chen, Tian-Lu Cheng and Shey-Cherng Tzou. (2017, Sep). Selective antibody activation through protease-activated proantibodies that mask binding sites with inhibitory domains. Scientific Reports, 7, 11587. (SCI, 10/64, Multidisciplinary sciences).

2016:

1. Yuan-Chin Hsieh, Ta-Chun Cheng, Hsin-Ell Wang, Jia-Je Li, Wen-Wei Lin, Chien-Chiao Huang, Chih-Hung Chuang, Yeng-Tseng Wang, Jaw-Yuan Wang, Steve R. Roffler, Kuo-Hsiang Chuang*, and Tian-Lu Cheng* (2016, Dec). Using anti-poly(ethylene glycol) bioparticles for the quantitation of PEGylated nanoparticles. Scientific Reports , DOI: 10.1038/srep39119. (SCI, 7/ 63, MULTIDISCIPLINARY SCIENCES).

2. Haur Lee, Yu-Lin Su, Bo-Shih Huang, Feng-Tse Hsieh, Ya-Hui Chang, Shiou-Ru Tzeng, Chun-Hua Hsu, Po-Tsang Huang, Kuo-Long Lou, Yeng-Tseng Wang and Lu-Ping Chow (2016, Nov). Importance of the C-terminal histidine residues of Helicobacter pylori GroES for Toll-like receptor 4 binding and interleukin-8 cytokine production. scientific reports , 6:37367. (SCI, 7/63, MULTIDISCIPLINARY SCIENCES). doi:10.1038/srep37367.

3. Wen-Wei Lin, Yuan-Chin Hsieh, Yi-An Cheng, Kuo-Hsiang Chuang, Chien-Chiao Huang⊥, Chih-Hung Chuang, I-Ju Chen, Kai-Wen Cheng, Yun-Chi Lu, Ta- Chun Cheng, Yeng-Tseng Wang, Steve R. Roffler*, and Tian-Lu Cheng* (2016, Nov). Optimization of an Anti-poly(ethylene glycol) (anti-PEG) Cell-Based Capture System To Quantify PEG and PEGylated Molecules. ANALYTICAL CHEMISTRY , DOI: 10.1021/acs.analchem.6b03614. (SCI, 4/75,CHEMISTRY, ANALYTICAL). DOI: 10.1021/acs.analchem.6b03614.

4. You-Hong Chen, Shih-Yu Kuo, Wei-Kai Tsai, Chi-Shiang Ke, Chia-Hsien Liao, Chuan-Pin Chen, Yeng-Tseng Wang, Hsiu-Wei Chen and Yang-Hsiang Chan* (2016, Nov). Dual Colorimetric and Fluorescent Imaging of Latent Fingerprints on Both Porous and Nonporous Surfaces with Near-Infrared Fluorescent Semiconducting Polymer Dot. Analytical Chemistry , 88 (23), 11616–11623. (SCI, 4/75,CHEMISTRY, ANALYTICAL). DOI: 10.1021/acs.analchem.6b03178.

5. Harika Meduru; Yeng-Tseng Wang; Jeffrey JP Tsai and Yu-Ching Chen* (2016, Jul). Finding a Potential Dipeptidyl Peptidase-4 (DPP-4) Inhibitor for Type-2 Diabetes Treatment Based on Molecular Docking, Pharmacophore Generation, and Molecular Dynamics Simulation. International Journal of Molecular Sciences , 17(6), 920.

6. Yeng-Tseng Wang*, Tian-Lu Cheng (2016, Jan). Refined Models of New Delhi metallo-beta-lactamase-1 with Inhibitors: An QM/MM Modeling Study . Journal of Biomolecular Structure and Dynamics . (SCI, 31/73, BIOPHYSICS). MOST 104-2113-M-037-014.

2015:

1. Pi-Jung Hsiao, Mei-Yueh Lee, Yeng-Tseng Wang, He-Jiun Jiang, Pi-Chen Lin, Yi-Hsin Connie Yang and Kung-Kai Kuo (2015, Oct). MTTP-297H polymorphism reduced serum cholesterol but increased risk of non-alcoholic fatty liver disease-a cross-sectional study.. BMC Medical Genetics , 16(1),93-103. (SCI, 110/167,GENETICS & HEREDITY).

2. Yeng-Tseng Wang*,Lea-Yea Chuang, Chi-Yu Lu (2015, Jun). Molecular basis of R294K mutation effects of H7N9 neuraminidases with drugs and cyclic peptides: an in silico and experimental study. RSC Advances , 5, 57568-57575. (SCI, 33/157, CHEMISTRY, MULTIDISCIPLINARY). MOST 103-2113-M-037-007.

3. Yeng-Tseng Wang*,Lea-Yea Chuang (2015, Jan). Insight into the modified Ibalizumab-human CD4 receptor interactions: using a computational binding free energy approach. Journal of Computer-Aided Molecular Design , 29(1), 69-78. (SCI, 13/102,COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS). MOST 101-2113-M-492-001-MY2. .

2014:

1. Kuo-Hsiang Chuang, Chien-Han Kao, Steve R. Roffler, Ssu-Jung Lu, Ta-Chun Cheng, Yun-Ming Wang, Chih-Hung Chuang, Yuan-Chin Hsieh, Yeng-Tseng Wang, Jaw-Yuan Wang, Kuo-Yi Weng and Tian-Lu Chen (2014, Nov). Development of an Anti-Methoxy Poly(ethylene glycol) (α-mPEG) Cell-Based Capture System to Measure mPEG and mPEGylated Molecules. . Macromolecules , 47( 19), 6880-6888. (SCI, 3/82, POLYMER SCIENCE).

2. Yeng-Tseng Wang*, Chi-Yu Lu, Tzyh-Chyuan Hour and Tian-Lu Cheng (2014, Nov). Inhibitor and Substrate Binding by New Delhi metallo-beta-lactamase-1: Molecular Mechanical Molecular Dynamics Studies. Current Computer-Aided Drug Design , 10,197-204. (SCI, 25/102, Computer Science, Interdisciplinary Applications). MOST 101-2113-M-037-011-MY2.

3. Nai-Wan Hsiao, Tien-Sheng Tseng, Yu-Ching Lee, Wang-Chuan Chen, Hui-Hsiung Lin, Yun-Ru Chen ,Yeng-Tseng Wang, Hung-Ju Hsu and Keng-Chang Tsai* (2014, Oct). Serendipitous Discovery of Short Peptides from Natural Products as Tyrosinase Inhibitors. Journal of Chemical Information and Modeling , 54(11), 3099-3111. (SCI, 6/135, COMPUTER SCIENCE, INFORMATION SYSTEMS)).

4. Kuo-Hsiang Chuang, Yuan-Chin Hsieh, I-Shiuan Chiang, Chih-Hung Chuang, Chien-Han Kao, Ta-Chun Cheng, Yeng-Tseng Wang, Wen-Wei Lin, Bing-Mae Chen, Steve R. Roffler, Ming-Yii Huang, Tian-Lu Cheng* (2014, Jul). High-Throughput Sorting of the Highest Producing Cell via a Transiently Protein-Anchored System. PLoS One , DOI: 10.1371/journal.pone.0102569. (SCI , 8/55, MULTIDISCIPLINARY SCIENCES).

5. Yeng-Tseng Wang*, Yu-Ching Chen (2014, Mar). Insights from QM/MM Modeling the 3D Structure of the 2009 H1N1 influenza A virus Neuraminidase and Its Binding Interactions with Antiviral Drugs. Molecular informatics , 33(3) ,240-249. (SCI, 15/47, Mathematical & Computational Biology). NSC 101-2113-M-492-001-MY2.

6. Wan-Sheng Su, Hsin-Tsung Chen, Jee-Gong Chang, Yeng-Tseng Wang, Wen-Jay Lee (2014, Feb). Investigation into the formation of 13-6 helical multi-shell gold nanowires. COMPUTATIONAL MATERIALS SCIENCE , 82(1), 226-230.. (SCIE, 72/241, MATERIALS SCIENCE, MULTIDISCIPLINARY). NSC 102-2218-E-492-002.

2013:

1. Yeng-Tseng Wang* (2013, Oct). Insights from modelling the 3D structure of the 2013 H7N9 influenza A virus neuraminidase and its binding interactions with drugs. MedChemComm, 4, 1370-1375. (SCI, 25/59, CHEMISTRY, MEDICINAL). NSC 101-2113-M-492-001-MY2.

2. Rui Li, Yeng-Tseng Wang, Cheng-Lung Chen* (2013, Jul). Why tazobactam and sulbactam have different intermediates population with SHV-1 β-lactamase: a molecular dynamics study.. Journal of Molecular Modeling, 19,2519–2524. (SCI, 28/102,COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS).

3. Rui Li, Yeng-Tseng Wang, Cheng-Lung Chen* (2013, Mar). Computer modeling on the tautomerization of sulbactam intermediate in SHV-1 β-lactamases: E166A mutant vs. wild type. Journal of Molecular Graphics and Modelling, 40, 131–139.. (SCI, 23/102, COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS).

2012:

1. Yeng-Tseng Wang*, Wen-Jay Lee (2012, Oct). Binding hot-spots in an antibody–ssDNA interface: a molecular dynamics study. Molecular BioSystems, 8, 3274-3280. (SCI, 106/290, BIOCHEMISTRY & MOLECULAR BIOLOGY). NSC 100-2113-M-492-001.

2. Zhi-Yuan Su, Wen-Jay Lee, Wan-Sheng Su and Yeng-Tseng Wang* (2012, Jun). Target Molecular Simulations of RecA Family Protein Filaments. International Journal of Molecular Sciences, 13, 7138-7148. (SCI, 48/152, CHEMISTRY, MULTIDISCIPLINARY). NSC 100-2113-M-492-001.

3. Yeng-Tseng Wang and Zhi-Yuan Su (2011, Sep). Free energies and folding mechanics between human prion fragment α-2 domain and β-2 domain under steered molecular dynamics simulations. Journal of the Taiwan Institute of Chemical Engineers, 42, 719–723. (SCI, 33/133, ENGINEERING, CHEMICAL).

2011:

1. Yeng-Tseng Wang,* Wen-Jay Lee, Zhi-Yuan Su* and Cheng-Lung Chen* (2011, Sep). Carbon-nanotube-based artificial peptide channel: Transportation of small peptide under external electric field force.. Journal of the Taiwan Institute of Chemical Engineers, 42, 724–726. (SCI, 33/133, ENGINEERING, CHEMICAL ).

2. Rui Li, Jun-Min Liao, Chi-Ruei Gu, Yeng-Tseng Wang and Cheng-Lung Chen (2011, Jul). Theoretical Investigation on Reaction of Sulbactam with Wild-type SHV-1 β-lactamase: Acylation, Tautomerization and Deacylation. Journal of Physical Chemistry B, 115, 10298-10310. (SCI, 34/134, CHEMISTRY, PHYSICAL).

3. Jun-Min Liao, Yeng-Tseng Wang and Cheng-Lung Chen (2011, May). Computer simulation to investigate the FRET application in DNA hybridization systems. Physical Chemistry Chemical Physics, 13, 10364-10371. (SCI, 31/134, CHEMISTRY, PHYSICAL).

4. Yeng-Tseng Wang,* Zhi-Yuan Su (2011, Feb). Modeling and predicting the binding mechanics of HIV P1053-0.5β antibody complex. Molecular Simulation, 37, 164-171. (SCI, 110/134, CHEMISTRY, PHYSICAL).

5. Zhi-Yuan Su, Yeng-Tseng Wang* (2011, Feb). Coarse-grained Molecular Dynamics Simulations of Cobra Cytotoxin A3 Interactions with a Lipid Bilayer: Penetration of Loops into Membranes. Journal of Physical Chemistry B, 115, 796-802. (SCI, 34/134, CHEMISTRY, PHYSICAL).

2010:

1. Yeng-Tseng Wang, Chen-hsiung Chan, Zhi-Yuan Su, Cheng-Lung Chen (2010, Mar). Homology modeling, docking, and molecular dynamics reveal HR1039 as a potent inhibitor of 2009 A(H1N1) influenza neuraminidase. BIOPHYSICAL CHEMISTRY, 147, 74-80. (SCI, 60/134, CHEMISTRY, PHYSICAL).

2009:

1. Yeng-Tseng Wang,* Zhi-Yuan Su, Cheng-Lung Chen (2009, Dec). Potential of Mean Force of the Hepatitis C Virus Core Protein-Monoclonal 19D9D6 Antibody Interaction. Biophysical Chemistry, 145, 86-90. (SCI, 60/134, CHEMISTRY, PHYSICAL).

2. Yeng-Tseng Wang,* Zhi-Yuan Su, Chang-Huain Hsieh, Cheng-Lung Chen (2009, Sep). Predictions of binding for dopamine D2 receptor antagonists derived from an SIE method. Journal of Chemical Information and Modeling , 49, 2369-2375. (SCI, 3/99, COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS).

3. Yeng-Tseng Wang,* Zhi-Yuan Su, Jun-Min Liao, Cheng-Lung Chen (2009, Sep). Potential of mean force for syrian hamster prion epitope protein – monoclonal fab 3f4 antibody interaction studies. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 44, 3504-3508. (SCI, 13/59, CHEMISTRY, MEDICINA). .

4. Tzuyin Wu, Lieh-Jung Chang, Shu-Yin Wang, Zhi-Yuan Su*, Yeng-Tseng Wang (2009, Jul). Nonlinear Analysis of the Estrous-cycle Time Series in Mice. Journal of the Korean Physical Society, 55, 1357-1362. (SCI, 69/84, PHYSICS, MULTIDISCIPLINARY).

5. Zhi-Yuan Su*, Yeng-Tseng Wang (2009, Apr). A Molecular Dynamics Simulation of the Human Lysozyme–Camelid VHH HL6 Antibody System. International Journal of Molecular Sciences, 10, 1719-1728. (SCI, 48/152, CHEMISTRY, MULTIDISCIPLINARY).

6. Zhi-Yuan Su*, Yeng-Tseng Wang (2009, Apr). An Investigation into the Multifractal Characteristics of the TAIEX Stock Exchange Index in Taiwan. Journal of the Korean Physical Society, 54, 1385-1394. (SCI, 64/84, PHYSICS, MULTIDISCIPLINARY).

7. Zhi-Yuan Su*, Yeng-Tseng Wang, Hsin-Yi Huang (2009, Apr). A Multifractal Detrended Fluctuation Analysis of Taiwan's Stock Exchange. Journal of the Korean Physical Society, 54, 1395-1402. (SCI, 69/83, PHYSICS, MULTIDISCIPLINARY).

2008:

1. Zhi-Yuan Su*, Tzuyin Wu, Yeng-Tseng Wang, Hsin-Yi Huang (2008, Aug). An investigation into the linear and nonlinear correlation of two music walk sequences. Physica D, 237, 1815-1824. (SCI, 20/245, MATHEMATICS, APPLIED).

2. Yeng-Tseng Wang,* Jun-Min Liao, Cheng-Lung Chen, Zhi-Yuan Su, Chang-Hung Cheng, Jeu-Jiun Hu (2008, Apr). Potential of mean force for human lysozyme-camelid vhh hl6 antibody interaction studies. Chemical Physics Letters, 455, 284-288. (SCI, 56/134, CHEMISTRY, PHYSICAL).

3. Zhi-Yuan Su*, Tzuyin Wu, Po-Hua Yang, Yeng-Tseng Wang (2008, Apr). Dynamic analysis of heartbeat rate signals of epileptics using multi-dimensional phase space reconstruction approach. Physica A, 387, 2293-2305. (SCI, 30/84, PHYSICS, MULTIDISCIPLINARY).

4. Zhi-Yuan Su*, Chuan-Chen Wang, Tzuyin Wu, Yeng-Tseng Wang, Feng-Cheng Tang (2008, Jan). Instantaneous frequency-time analysis of physiology signals: The application of pregnant women's pulse signals. Physica A, 387, 458-494. (SCI, 30/84, PHYSICS, MULTIDISCIPLINARY).

2007:

1. Wang, Yeng-Tseng*, Cheng, Cheng-Lung, Shih, Yu-Ching, Kan, Heng-Chuan, Chen,Chang-Hung, Hu, Jeu-Jiun, Su, Zhi-Yuan (2007, Aug). Molecular dynamics simulation of the binding interaction between hormone glucagon protein and self-assembled monolayer molecules. Chinese Journal of Chemistry , 25, 1090-1093. (SCI, 99/152, CHEMISTRY, MULTIDISCIPLINARY).