Publications

Our publications with plenty of undergraduate co-authors since 2006 (the year we started our lab at W&M)

See below or view MyBibliogrphy on the NCBI website:  https://www.ncbi.nlm.nih.gov/myncbi/oliver.kerscher.1/bibliography/public/

1) Hutson C, Li S, Sweeney K, Kerscher O. 2025. Identification and functional analysis of ULP2 SUMO protease mutants of the stress-tolerant yeast Kluyveromyces marxianus. microPublication Biology. 10.17912/micropub.biology.001816.

2) Rinehart L, Stewart WE, Luffman N, Wawersik M, Kerscher O. Chigno/CG11180 and SUMO are Chinmo-interacting proteins with a role in Drosophila testes somatic support cells. PeerJ. 2024 Mar 14;12:e16971. doi: 10.7717/peerj.16971. PMID: 38495765; PMCID: PMC10944633. 

3) Chemical Genetics Screen of EVP4593 Sensitivity in Budding Yeast Identifies Effects on Mitochondrial Structure and Function. (2023) Hiestand, L*; Shen, S*; Sloan, W; Nasiri, H; Lashley, D; Kerscher, O (2023).  microPublication Biology. 10.17912/micropub.biology.000806.* joint first authers

4) Protein Modification Employing Non-Canonical Amino Acids to Prepare SUMOylation Detecting Bioconjugates. (2022) - Williard AC, Switzer HJ, Howard CA, Yin R, Russell BL, Sanyal R, Yu S, Myers TM, Flood BM, Kerscher O, Young DD. Dec 16;14(12):2826. doi: 10.3390/pharmaceutics14122826. PMID: 36559319; PMCID: PMC9784311.

5) Detection of Rapidly Accumulating Stress-Induced SUMO in Prostate Cancer Cells by a Fluorescent SUMO Biosensor (2021) Rui Yin, Jiacheng Song, Aurora Esquela-Kerscher, and Oliver Kerscher - Molecular Carcinogenesis. 2021;1‐12. https://doi.org/10.1002/mc.23353

6) Pilc EM, Ganesh S, Kerscher O. A genome-wide screen in Saccharomyces cerevisiae identifies Tannic Acid-sensitive mutants. MicroPubl Biol. 2021 Jan 14;2021:10.17912/micropub.biology.000358. doi: 10.17912/micropub.biology.000358. PMID: 33474531; PMCID: PMC7812385. 10.17912/micropub.biology.000358. 

7) Rui Yin, Catherine Harvey, Diane Shakes, and Oliver Kerscher ; Localization of SUMO-Modified Proteins using fluorescent SUMO-Trapping Proteins (2019) J. Vis. Exp.(146), e59576, doi:10.3791/59576

8)  Dylan T. Simpson, Molly S. Teague, Joanna K. Weeks, Brent Z. Kaup, Oliver Kerscher, Matthias Leu (2019) Habitat amount, quality, and fragmentation associated with prevalence of the tick-borne pathogen Ehrlichia chaffeensis and occupancy dynamics of its vector, Amblyomma americanum. Landscape Ecology, Volume 34, Issue 10, pp 2435–2449

9) Ohkuni K, Pasupala N, Peek J, Holloway GL, Sclar GD, Levy-Myers R, Baker RE, Basrai MA and Kerscher O (2018) SUMO-Targeted Ubiquitin Ligases (STUbLs) Reduce the Toxicity and Abnormal Transcriptional Activity Associated With a Mutant, Aggregation-Prone Fragment of Huntingtin. Front. Genet. 9:379. doi: 10.3389/fgene.2018.00379.

10) Simpson, D. T.*, M. S. Teague, J. K. Weeks, A. D. Lewis, P. M. D’Addio, J. D. Moore, J. A. Thompson, A. C. Harris, R. T. Cannellaa, B. Z. Kaup, O. Kerscher, M. Leu. (2018) Broad, Multi-Year Sampling Effort Highlights Complex Dynamics of the Tick-Borne Pathogen Ehrlichia chaffeensis (Rickettsiales: Anaplasmatacae). Journal of Medical Entomology, Volume 56, Issue 1, 8 January 2019, Pages 162–168 tjy171, https://doi.org/10.1093/jme/tjy171 

11) SUMO targeting of a stress-tolerant Ulp1 SUMO protease. (2018) Peek J, Harvey C, Gray D, Rosenberg D, Kolla L, Levy-Myers R, Yin R, McMurry JL, Kerscher O. PLoS One. 2018 Jan 19;13(1):e0191391. doi: 10.1371/journal.pone.0191391. eCollection 2018.

12) Ohkuni K, Takahashi Y, Fulp A, Lawrimore J, Au WC, Pasupala N, Levy-Myers R, Warren J, Strunnikov A, Baker RE, Kerscher O.,Bloom K, Basrai MA.(2016) SUMO-Targeted Ubiquitin Ligase (STUbL) Slx5 regulates proteolysis of centromeric histone H3 variant Cse4 and prevents its mislocalization to euchromatin. Mol Biol Cell. 2016 Mar 9. pii: mbc.E15-12-0827.[Epub ahead of print]

13) SUMOylation (2016) Oliver Kerscher eLS review (in press) In: eLS. JohnWiley & Sons, Ltd: Chichester. DOI: 10.1002/9780470015902.a0021849.pub2 

14) A SUMO-targeted ubiquitin ligase is involved in the degradation of the nuclear pool of the SUMO E3 ligase Siz1 (2013) Jason W Westerbeck*, Nagesh Pasupala*, Mark Guillotte, Eva Szymanski, Brooke CMatson, Cecilia Esteban, and Oliver Kerscher -- Mol. Biol. Cell January 1, 2014 vol. 25 no. 1 1-16         * denotes joint first authors

15)  Szymanski, E. P., Kerscher, O. Budding Yeast Protein Extraction and Purification for the Study of Function, Interactions, and Post-translational Modifications. J. Vis. Exp. (80), e50921, doi:10.3791/50921 (2013) 

16) Cytoplasmic localization of Hug1p, a negative regulator of the MEC1 pathway, coincides with the compartmentalization of Rnr2p-Rnr4p (2013) William B. Ainsworth; Bridget Todd Hughes, Wei Chun Au,  Sally Sakelaris, Oliver Kerscher, Michael G Benton, and Munira A. Basrai -- Biochem Biophys Res Commun. 2013 Sep 5. pii: S0006-291X(13)01447-2. doi: 10.1016/j.bbrc.2013.08.089. [Epub ahead of print]

17) The SUMO-targeted ubiquitin ligase RNF4 regulates localization and function of the HTLV-1 oncoprotein Tax (2011).  Kimberly A Fryrear, Xin Guo, Oliver Kerscher and Oliver J Semmes (Published online before print November 21, 2011, doi:10.1182/blood-2011-06-358564)

18) Sumo-dependent Substrate targeting of the SUMO Protease Ulp1 (2011) Zachary Elmore, Megan Donaher, Brooke Matson, Helen Murphy, Jason Westerbeck, and Oliver Kerscher. BMC Biology 2011, 9:74 (28 October 2011)

19) Cook, E. C, Hochstrasser, M., Kerscher, O. (2009) The SUMO-targeted ubiquitin ligase subunit Slx5 resides in nuclear foci and at sites of DNA breaks Cell Cycle. 8(7): 1080–1089. 

20) Yang Xie* , Oliver Kerscher* , Mary B. Kroetz , Heather F. McConchie , Patrick Sung , Mark Hochstrasser. (2007) The yeast HEX3-SLX8 heterodimer is a ubiquitin ligase stimulated by substrate sumoylation. J. Biol Chem. 23(47)34176-34184* denotes joint first authors

21) Kerscher O. (2007) SUMO junction-what's your function? New insights through SUMO-interacting motifs. EMBO Reports 8(6): 550-555

22) Kerscher, O., Felberbaum, R. and Hochstrasser, M. (2006) Modification of proteins by ubiquitin and ubiquitin-like proteins. Annu Rev Cell Dev Biol, 22, 159-180.