Jen-Hau Yang (楊仁豪)
Assistant Professor,
Doctoral Program of Clinical and Experimental Medicine,
National Sun Yat-sen University
專任助理教授,
臨床醫學科學博士學位學程
國立中山大學
Jen-Hau Yang (楊仁豪)
Assistant Professor,
Doctoral Program of Clinical and Experimental Medicine,
National Sun Yat-sen University
專任助理教授,
臨床醫學科學博士學位學程
國立中山大學
Education/學經歷
Postdoctoral Associate, Department of Psychiatry, Yale University School of Medicine
博士後研究員, 耶魯大學醫學院/精神病理學系 2019 – 2023
Ph.D., Behavioral Neuroscience in Department of Psychological Sciences, University of Connecticut
博士學位, 康乃狄克大學心理學系/行為神經科學 2015 – 2019
M.S., Experimental Psychology, National Chengchi University
碩士學位, 國立政治大學/實驗心理學 2008 – 2011
B.S., Psychology, National Chengchi University
學士學位, 國立政治大學/心理學系 2004 – 2008
Selected Publications (Google scholar page)
Wong LS, Yang JL, Yen YT, Lee CH, Yang JH. (2025). Endothelin-1 participates pathogenesis of prurigo nodularis by promoting NGF expression via endothelial receptor B in epidermal keratinocytes and dorsal root ganglion cells. Allergy, 80(5):1530-1533.
Yang JH, Basu A, Liu RJ, Staszko S, Yu AL, Rondeau J, Glaeser-Khan S, Zhuo Y, Feng J, Li Y, Che A, Kaye A. Frontal cortex norepinephrine, serotonin, and dopamine dynamics in an innate fear-reward behavioral model. BioRxiv, doi: https://doi.org/10.1101/2023.11.27.568929 (Under Revision)
Yu A, Rosado A, Yang JH, Rondeau J, Basu A, Dibbs M, Feng J, Li YL, Warner-Schmidt J, Kelmendi B, Krystal J, Pittenger C, Kwan A. Norepinephrine blocks psychedelic-like effects of entactogens and psilocybin in mice. (Under Revision)
Kelberman MA, Rodberg E, Arabzadeh E, Bair-Marshall CJ, Berridge CW, Berrocoso E, Breton-Provencher V, Chandler DJ, Che A, Davy O, Devilbiss DM, Downs AM, Drummond G, Dvorkin R, Fazlali Z, Froemke RC, Glennon E, Gold JI, Ito H, Jiang X, Johansen JP, Kaye AP, Kim JR, Kuo CC, Liu RJ, Liu Y, Llorca-Torralba M, McCall JG, McElligott ZA, McKinney AM, Miguelez C, Min MY, Nowlan AC, Omrani M, Poe GR, Pickering AE, Ranjbar-Slamloo Y, Razquin J, Rodenkirch C, Sales AC, Satyasambit R, Shea SD, Sur M, Tkaczynski JA, Torres-Sanchez S, Uematsu A, Vazquez CR, Vreven A, Wang Q, Waterhouse BD, Yang HW, Yang JH, Zhao L, Zouridis IS, Weinshenker D, Vazey E, Totah NK. Diversity of ancestral brainstem noradrenergic neurons across species and multiple biological factors. BioRxiv, doi: https://doi.org/10.1101/2024.10.14.618224 (Manuscript submitted)
Basu A, Yang JH, Yu A, Glaeser-Khan S, Rondeau JA, Feng J, Krystal JH, Li Y, Kaye AP (2024). Frontal norepinephrine represents a threat prediction error under uncertainty. Biological Psychiatry, 15;96(4):256-267. doi: 10.1016/j.biopsych.2024.01.025.
Ecevitoglu A, Edelstein GA, Presby RE, Rotolo RA, Yang JH, Quiles T, Okifo K, Conrad R, Kovach A, Correa M, Salamone JD (2023). Effects of the Atypical Antipsychotic and D3/D2 Dopamine Partial Agonist Cariprazine on Effort-based Choice Behavior: Implications for Modeling Avolition. Psychopharmacology 240,1747–1757.
Jefferson SJ, Wehrle PH, Yang JH, Rivera MN, Kaye AP. Deep phenotyping analysis of acute psychedelic effects. (Manuscript in preparation)
Yang JH, Kwan AC (2021). Secondary motor cortex: Broadcasting and biasing animal's decisions through long-range circuits. International Review of Neurobiology, 158: 443 – 470. doi: 10.1016/bs.irn.2020.11.008.
Rotolo RA, Presby RE, Tracy O, Asar S, Yang JH, Correa M, Murray F, Salamone JD (2021). The novel atypical dopamine transport inhibitor CT-005404 has pro-motivational effects in neurochemical and inflammatory models of effort-based dysfunctions related to psychopathology. Neuropharmacology, 1;183:108325. doi: 10.1016/j.neuropharm.2020.108325.
Yang JH, Presby RE, Rotolo RA, Quiles T, Okifo K, Zorda E, Fitch RH, Correa M, Salamone JD (2020). The dopamine depleting agent tetrabenazine alters effort-related decision making as assessed by mouse touchscreen procedures. Psychopharmacology (Berl), 237(9): 2845 – 2854. doi: 10.1007/s00213-020-05578-w.
Yang JH, Presby RE, Cayer S, Rotolo RA, Perrino PA, Fitch RH, Correa M, Chesler EJ, Salamone JD (2020). Effort-related decision making in humanized COMT mice: Effects of Val158Met polymorphisms and possible implications for negative symptoms in humans. Pharmacology, Biochemistry, and Behavior, 196:172975. doi: 10.1016/j.pbb.2020.172975.
Yang JH, Presby RE, Jarvie AA, Rotolo RA, Fitch RH, Correa M, Salamone JD (2020). Pharmacological studies of effort-related decision making using mouse touchscreen procedures: Effects of dopamine antagonism do not resemble reinforcer devaluation by removal of food restriction. Psychopharmacology (Berl), https://doi.org/10.1007/s00213-019-05343-8.
Presby RE, Rotolo RA, Yang JH, Correa M, Salamone JD (2020). Lisdexamfetamine suppresses instrumental and consummatory behaviors supported by foods with varying degrees of palatability: Exploration of a binge-like eating model. Pharmacology, Biochemistry, and Behavior, 189:172851. doi: 10.1016/j.pbb.2020.172851.
Rotolo RA, Kalaba P, Dragacevic V, Presby RE, Neri J, Robertson E, Yang JH, Correa M, Bakulev V, Volkova NN, Pifl C, Lubec G, Salamone JD (2020). Behavioral and dopamine transporter binding properties of the modafinil analog (S, S)-CE-158: reversal of the motivational effects of tetrabenazine and enhancement of progressive ratio responding. Psychopharmacology (Berl), 237(11):3459 – 3470. doi: 10.1007/s00213-020-05625-6.
Rotolo RA, Dragacevic V, Kalaba P, Urban E, Zehl M, Roller A, Wackerlig J, Langer T, Pistis M, De Luca MA, Caria F, Schwartz R, Presby RE, Yang JH, Samels S, Correa M, Lubec G, Salamone JD (2019). The Novel Atypical Dopamine Uptake Inhibitor (S)-CE-123 Partially Reverses the Effort-Related Effects of the Dopamine Depleting Agent Tetrabenazine and Increases Progressive Ratio Responding. Frontiers in Pharmacology, 28;10:682. doi: 10.3389/fphar.2019.00682.
Yang JH, Cheng CC, Liao RM (2018). Effects of d-amphetamine on risk choice behavior in rats depend on the manner in which the expected reward value is varied. Pharmacology, Biochemistry and Behavior, 171: 20 – 29.
Salamone JD, Correa M, Ferrigno S, Yang JH, Rotolo R, Presby R (2018). The Psychopharmacology of Effort-related Decision Making: Dopamine, Adenosine, and Insights into the Neurochemistry of Motivation. Pharmacological reviews, 70:747 – 762.
Salamone JD, Correa M, Yang JH, Rotolo R, Presby R (2018). Dopamine, Effort-based Choice, and Behavioral Economics: Basic and Translational Research. Frontiers in Behavioral Neuroscience, doi: 10.3389/fnbeh.2018.00052.
Salamone JD, Correa M, Yohn SE, Yang JH, Sommerville M, Rotolo R, Presby R (2017). Behavioral activation, effort-based choice, and elasticity of demand for motivational stimuli: basic and translational neuroscience approaches. Motivation Science, 3(3): 208-229.
Yang JH, Liao RM (2015). Dissociable contribution of nucleus accumbens and dorsolateral striatum to the acquisition of risk choice behavior in the rat. Neurobiology of Learning and Memory, 126, 67-77.
Updated: May, 2025