Publications

Submitted / in revision :

•  Yangjin Kim, Donggu Lee, Junho Lee, and Sean Lawler, Role of tumor-associated neutrophils and neutrophil elastase in regulation of lung cancer growth and growth patterns, in revision, 2021.

•  Yoshihiro Otani, Yangjin Kim, Junho Lee, Ji Young Yoo, Samantha Chao, Jessica Swanner, Toshihiko Shimizu, Cole T Lewis, Jin Muk Kang, Sara A Murphy, Josue Pineda, Kimberly Rivera Caraballo, Bridgitte E Palacios, Bangxing Hong, E Antonio Chiocca, Hiroshi Nakashima, Sean E Lawler, Yeshavanth Banasavadi-Siddegowda, John Heiss, Yuanqing Yan, Abhinav K Jain, Arif O Harmanci, Scott D. Olson, Guangsheng Pei, Zhongming Zhao, Avner Friedmany, and Balveen Kaury, Activated NOTCH induced monocyte recruitment suppresses anti-tumor immunity with virotherapy, Nature Immunology (IF=20), submitted, 2021.

Published / accepted :

• Donggu Lee, Sunju Oh, Sean Lawler, Yangjin Kim, Bistable dynamics of TAN-NK cells in tumor growth and control of radiotherapy-induced neutropenia in lung cancer treatment, Math Biosc. Eng., 22(4), 744-809, Mar 04, 2025

• Donggu Lee, Aurelio A. De Los Reyes V, Yangjin Kim, Optimal strategies of oncolytic virus-bortezomib therapy via the apoptotic, necroptotic, and oncolysis signaling network, Math Biosc. Eng., 21(3), 3876-3909, Feb 2024 (link)

•  Yangjin Kim, Junho Lee, Chaeyoung Lee, and Sean Lawler, Role of senescent tumor cells in building a cytokine shield in the tumor microenvironment: mathematical modeling, J Math Biol, 86(1), 14, 2023. (pubmed)

•  Aurelio A. de los Reyes V and Yangjin Kim, Optimal regulation of tumor-associated neutrophils in lung cancer progression, R. Soc. Open Sci., 9, 210705, Feb 2022. (link)

•  Junho Lee, Jinsu Kim, and Yangjin Kim, Atorvastatin-mediated rescue of cancer-related cognitive changes in combined anticancer therapies, PLoS Comp Biol, 17(10), e1009457, Oct 2021. (link,pubmed)

•  Jonggul Lee, Donggu Lee, and Yangjin Kim, Mathematical model of STAT signaling pathways in cancer development and optimal control approaches, J Royal Society Open Science, 8(9), 210594, Sep 2021. (link,pubmed)

•  Junho Lee, Donggu Lee, Sean Lawler, and Yangjin Kim, Role of neutrophil extracellular traps in regulation of lung cancer invasion and metastasis: Structural Insights from a Computational Model, PLoS Comp Biol, 17(2), e1008257, Feb 2021. (link,pubmed)

•  Angelica P Aspirin, Aurelio A. de los Reyes V, and Yangjin Kim, Polytherapeutic strategies with oncolytic virus-bortezomib and adjuvant NK cells in cancer treatment, J Roy Soc Interface, 18(174), 20200669, Jan 06, 2021. (link, pubmed)

•  Yangjin Kim, Donggu Lee, and Sean Lawler, Collective invasion of glioma cells through OCT1 signaling and interaction with reactive astrocytes after surgery, Phil. Trans. Roy. Soc. B, 375, 20190390, July 27, 2020. (link, pubmed)

•  Eunok Jung, Aurelio A. de los Reyes V, Kurt Jan A. Pumares, and Yangjin Kim, Strategies in regulating glioblastoma signaling pathways and anti-invasion therapy, PLoS One, 14(4): e0215547, Apr 23, 2019. (link, pubmed)

•  Yangjin Kim, Junho Lee, Donggu Lee and Hans G. Othmer, Synergistic Effects of Bortezomib-OV Therapy and Anti-Invasive Strategies in Glioblastoma: A Mathematical Model, Cancers, 11(2), 215, Feb 2019. (link, pubmed)

•  Yangjin Kim, Donggu Lee, Junho Lee, Seongwon Lee, Sean Lawler, Role of tumor-associated neutrophils in regulation of tumor growth in lung cancer development: A mathematical model, PLoS One, 14(1): e0211041, Jan 28, 2019. (link, pubmed)

•  Yangjin Kim, Hyunji Kang, Gibin Powathil, Hyeongi Kim, Dumitru Trucu, Wanho Lee, Sean Lawler, and Mark Chaplain, Role of extracellular matrix and microenvironment in regulation of tumor growth and LAR-mediated invasion in glioblastoma, PLoS One, 13(10):e0204865, Oct 4, 2018 (link, Pubmed)

•  Yangjin Kim, Ji Young Yoo, Tae Jin Lee, Joseph Liu, Jianhua Yu, Michael A Caligiuri, Balveen Kaur, and Avner Friedman, Complex Role of NK cells in regulation of OV-Bortezomib therapy, Proc Natl Acad Sci,, 115 (19) 4927-4932, May 8, 2018 (link, pubmed)

•  Yangjin Kim, Wanho Lee, Hyejin Jeon, Sookkyung Lim, Soyeon Roh, Donggu Lee, Junho Lee, and Sean Lawler, The role of microenvironment in regulation of cell infiltration in glioblastoma, Springer volume: Cell Movement: Modeling and Applications, Editors: Stolarska, Magdalena, Tarfulea, Nicoleta E, 27-60, 2018. ISBN 978-3-319-96842-1. (Springer book)

•  Yangjin Kim, Hyejin Jeon, and Hans Othmer, The role of the tumor microenvironment in glioblastoma: A mathematical model,, IEEE Trans Biomed Eng, 64(3):519-527, March 2017. (pubmed)

•  Wanho Lee, Sookkyung Lim, and Yangjin Kim, The role of myosin II in glioma invasion: A mathematical model, PLoS One, 12(2): e0171312. Feb 06, 2017 (pubmed)

•  Ji Sun Lim, Seongwon Lee, and Yangjin Kim, Hopf bifurcation in a model of TGF-beta in regulation of the Th 17 phenotype, Discrete and Continuous Dynamical Systems-B, 21(10), 3575-3602, Dec 2016. (link)

•  Shinji Nakaoka, Sota Kuwahara, Changhyeong Lee, Hyejin Jeon, Junho Lee, Yasuhiro Takeuchi, and Yangjin Kim, Chronic inflammation in the epidermis: A mathematical model, Appl. Sci., 6(9), 252, Sep 2016. (link)

•  Hyun Geun Lee and Yangjin Kim, The role of the microenvironment in regulation of CSPG- driven invasive and non-invasive tumor growth in glioblastoma, Japan J. Indust. Appl. Math., 32 (3) , 771-805 (Jan 2016). (link)

•  Hyun Geun Lee, Yangjin Kim, and Junseok Kim, Mathematical model and its fast numerical method for the tumor growth, Math Bios Eng, 12 (6), 1173-1187, Dec 2015. (pubmed)

•  Yangjin Kim and Hans Othmer, Hybrid models of cell and tissue dynamics in tumor growth, Math Bios Eng, 12 (6), 1141-1156, Dec 2015. (pubmed)

•  Aurelio A. de los Reyes V, Eunok Jung, and Yangjin Kim, Optimal strategies of eradicating invisible glioblastoma cells after conventional surgery, J Roy Soc Interface, 12 (106), 20141392, (May 6, 2015). [IF=3.917] (link, pubmed)

•  Yangjin Kim, Gibin Powathil, Hyunji Kang, Dumitru Trucu, Hyeongi Kim, Sean Lawler, and Mark Chaplain, Strategies of eradicating glioma cells: A multi-scale mathematical model with miR-451-AMPK-mTOR control, PLoS One, 10(1):e0114370, (Jan 28, 2015). [ DOI: 10.1371/journal.pone.0114370, 2015 ]. (pubmed)

•  Yangjin Kim, Hyunji Kang, and Sean Lawler, The Role of the miR-451-AMPK Signaling Pathway in Regulation of Cell Migration and Proliferation in Glioblastoma, in `Mathematical Models of Tumor-Immune System Dynamics', Springer Proceedings in Mathematics & Statistics, Springer, New York, 107, 125-155, (Oct 18, 2014). (link)

•  Yangjin Kim, Hyungeun Lee, Nina Dmitrieva, Balveen Kaur, Junseok Kim, and Avner Friedman, Choindroitinase ABC I-mediated enhancement of oncolytic virus spread and anti-tumor efficacy: A mathematical model, PLoS One, 9(7), e102499 (July 21, 2014). [ DOI 10.1371/journal.pone.0102499 ]. (pubmed)

•  Seongwon Lee, Hyung Ju Hwang, Yangjin Kim, Modeling the role of TGF-beta in regulation of the Th17 phenotype in the LPS-driven immune system, Bull Math Biol., 76 (5), 1045-1080 (May, 2014) [ DOI 10.1007/s11538- 014-9946-6 ]. (pubmed)

•  Heinz Schattler, Yangjin Kim, Urszula Ledzewicz, Aurelio A. de los Reyes V, and Eunok Jung, On the control of cell migration and proliferation in glioblastoma, Proceeding of the IEEE Conference on Decision and Control, 978-1-4673-5716-6/13, 1810-1815 (Dec, 2013) (link)

•  Yangjin Kim, Seongwon Lee, You-Sun Kim, Yoon-Keun Kim, Yong Song Gho, Hyung Ju Hwang, Sean Lawler, Regulation of Th1/Th2 cells in asthma development: A mathematical model, Math. Bios. Eng., 10(4), 1095-1133, (Aug, 2013). (pubmed)

•  Yangjin Kim and Hans Othmer, A hybrid model of tumor-stromal interactions in breast cancer, Bull Math Biol, 75, 1304-1350 (Aug, 2013) [ DOI 10.1007/s11538-012-9787-0 ] (pubmed)

•  Yangjin Kim and Soyeon Roh, A hybrid model of cell proliferation and migration in glioblastoma, Discrete and Continuous Dynamical Systems-B, 18 (4), 969-1015 (June 2013). (link)

•  Yangjin Kim, Regulation of cell proliferation and migration in glioblastoma: New therapeutic approach, Frontiers in Molecular and Cellular Oncology, 3, 53 (Mar 2013). doi: 10.3389/fonc.2013.00053 (link)

•  Yangjin Kim and Khalid Boushaba, Regulation of Tumor Dormancy and Role of Microenvironment: A Mathematical Model, Systems Biology of Tumor Dormancy, Advances in Experimental Medicine and Biology, Heiko Enderling, Nava Almog, Lynn Hlatky (Eds.), Springer, New York, 734, 237-259 (2013). (link)

•  Yangjin Kim, Soyeon Roh, Sean Lawler, and Avner Friedman, miR451 and AMPK mutual antagonism in glioma cells migration and proliferation, PLoS One, 6(12), e28293 (Dec 20, 2011). [doi:10.1371/journal.pone.0028293] (Link)

•  Marisa Eisenberg, Yangjin Kim, Ruth Li, William E. Ackerman, Douglas A. Kniss, and Avner Friedman, Modeling the effects of myoferlin on tumor cell invasion, Proc Natl Acad Sci USA, 108(50), 20078-83 (Dec 13, 2011) [doi: 10.1073/pnas.1116327108]. (PNAS link, Pubmed link)

•  Yangjin Kim and Khalid Boushaba, An enzyme kinetics model of tumor dormancy, regulation of secondary metastases, Discrete and Continuous Dynamical Systems-S, 4(6), 1465-1498 (Dec, 2011). (link pdf)

•  Baltazar D. Aguda, Yangjin Kim, Hong Sug Kim, Avner Friedman, Howard A. Fine, Qualitative network modeling of the MYC-p53 control system of cell proliferation and differentiation, Biophysical Journal, 101(9), 2082-2091 (Nov, 2011). (link, Pubmed link) (This paper was selected as a featured article)

•  Yangjin Kim, Magdalena Stolarska, and Hans G. Othmer, The Role of The Microenvironment in Tumor Growth and Invasion, Progress in Biophysics and Molecular Biology, 106, 353-379 (Aug, 2011) [ doi:10.1016/j.pbiomolbio.2011.06.006 ]. (link, Pubmed link)

•  Avner Friedman and Yangjin Kim, Tumor cells proliferation and migration under the influence of their microenvironment, Mathematical Biosciences and Engineering, 8(2), 373-385, (Apr, 2011). (link, pdf, Pubmed link)

•  Yangjin Kim and Sookkyung Lim, The role of the microenvironment in tumor invasion, 2009 Proceedings of the Fourth SIAM Conference on Mathematics for Industry (MI09), 84-92 (2010). (link)

•  Yangjin Kim and Avner Friedman, Interaction of tumor with its microenvironment : A Mathematical Model, Bull.Math.Biol., 72(5), 1029-1068 (2010) [DOI 10.1007/s11538-009-9481-z]. (link, pubmed)

•  Yangjin Kim, Julie Wallace, Fu Li, Michael Ostrowski and Avner Friedman, Transformed epithelial cells and fibroblasts/myofibroblasts interaction in breast tumor: a mathematical model and experiments, J Math Biol, 61(3), 401-421 (2010) [DOI 10.1007/s00285-009-0307-2]. (link, pubmed)

•  Magdalena Stolarska, Yangjin Kim, and Hans G. Othmer, Multi-scale models of cell and tissue dynamics, Phil. Trans. Roy. Soc. A, 367, 3525-3553 (2009). (link, pubmed)

•  Yangjin Kim, Sean Lawler, Michal O. Nowicki, E. Antonio Chiocca, and Avner Friedman, A mathematical model of Brain tumor : pattern formation of glioma cells outside the tumor spheroid core, J Theo Biol, 260, 359-371 (2009) [doi:10.1016/j.jtbi.2009.06.025] (link, pubmed)

•  Baltazar D. Aguda, Yangjin Kim, Melissa G. Hunter, Avner Friedman, and Clay B. Marsh, MicroRNA Regulation of a Cancer Network: Consequences of the Feedback Loops Involving miR-17-92, E2F, and Myc, Proc Natl Acad Sci, 105(50), 19678-19683 (2008). (pdf, link, pubmed)

•  Yangjin Kim, Magdalena Stolarska, and Hans G. Othmer, A hybrid model for tumor spheroid growth in vitro I: Theoretical development and early results, Math. Models Methods in Appl Scis, 17, 1773-1798 (2007), (link)

•  Ph.D thesis: Yangjin Kim, 'Mathematical modeling of cell movement and tumor spheroid growth in vitro' (2006).