Current  Research Project:

1. Pharmacokinetics and pharmacodynamics of the myotoxic/nephrotoxic venom of Daboia siamensis (Russell’s viper) in the anesthetized rat

(TRF research grant 2016)

2. Sudden cardiac collapse and cardiovascular disturbances following envenomation by Malayan krait (Bungarus candidus)

(NSTDA research grant 2015)

Publication during PhD candidature

1. Hypotensive and vascular relaxant effects of phospholipase A2 toxins from Papuan taipan (Oxyuranus scutellatus) venom. Chaisakul J, Isbister GK, Tare M, Parkington HC, Hodgson WC. Eur J Pharmacol. 2014; 723: 227-33.

2. An examination of cardiovascular collapse induced by eastern brown snake (Pseudonaja textilis) venom. Chaisakul J, Isbister GK, Kuruppu S, Konstantakopoulos N, Hodgson WC. Toxicol Lett. 2013; 221(3): 205-11.

3. Differential myotoxic and cytotoxic activities of pre-synaptic neurotoxins from Papuan taipan (Oxyuranus scutellatus) and Irian Jayan death adder (Acanthophis rugosus) venoms. Chaisakul J, Parkington HC, Isbister GK, Konstantakopoulos N, Hodgson WC. Basic Clin Pharmacol Toxicol. 2013; 112(5):325-34.

4. In vivo and in vitro cardiovascular effects of Papuan taipan (Oxyuranus scutellatus) venom: Exploring "sudden collapse". Chaisakul J, Isbister GK, Konstantakopoulos N, Tare M, Parkington HC, Hodgson WC. Toxicol Lett. 2012; 213(2):243-8.

5. Isolation and characterisation of P-EPTX-Ap1a and P-EPTX-Ar1a: pre-synaptic neurotoxins from the venom of the northern (Acanthophis praelongus) and Irian Jayan (Acanthophis rugosus) death adders. Chaisakul J, Konstantakopoulos N, Smith AI, Hodgson WC. Biochem Pharmacol. 2010 ;80(6): 895-902.

Publication after PhD candidature

1. Effect of Animal Venoms and Toxins on Hallmarks of Cancer. Chaisakul J, Hodgson WC, Kuuruppu S, Prasongsook N. J Cancer. 2016;7(11):1571-1578

2. Prothrombin activator-like toxin appears to mediate cardiovascular collapse following envenoming by Pseudonaja textilis. Chaisakul J, Isbister GK, O'Leary MA, Parkington HC, Smith AI, Hodgson WC, Kuruppu S. Toxicon. 2015; 102:48-54.

3. In vitro toxic effects of puff adder (Bitis arietans) venom, and their neutralization by antivenom. Fernandez S, Hodgson WC, Chaisakul J, Kornhauser R, Konstantakopoulos N, Smith AI, Kuruppu S. Toxins. 2014 May 19; 6(5):1586-97.

4. Inhibition of presynaptic neurotoxins in taipan venom by suramin. Kuruppu S, Chaisakul J, Smith AI, Hodgson WC. Neurotox Res. 2014; 25(3):305-10.

 5. Evaluation of the geographical utility of Eastern Russell's viper (Daboia siamensis) antivenom from Thailand and an assessment of its protective effects against venom-induced nephrotoxicity. Chaisakul J, Alsolaiss J, Charoenpitakchai M, Wiwatwarayos K, Sookprasert N, Harrison RA, Chaiyabutr N, Chanhome L, Tan CH, Casewell NR. PLoS Negl Trop Dis. 2019 Oct 23;13(10):e0007338. doi: 10.1371/journal.pntd.0007338. 

6. Non-neurotoxic activity of Malayan krait (Bungarus candidus) venom from Thailand. Charoenpitakchai M, Wiwatwarayos K, Jaisupa N, Rusmili MRA, Mangmool S, Hodgson WC, Ruangpratheep C, Chanhome L, Chaisakul J. J Venom Anim Toxins Incl Trop Dis. 2018 Mar 9;24:9. doi: 10.1186/s40409-018-0146-y. eCollection 2018. 

7. A Pharmacological Examination of the Cardiovascular Effects of Malayan Krait (Bungarus candidus) Venoms. Chaisakul J, Rusmili MR, Hodgson WC, Hatthachote P, Suwan K, Inchan A, Chanhome L, Othman I, Chootip K. Toxins (Basel). 2017 Mar 29;9(4). pii: E122. doi: 10.3390/toxins9040122.

 8. Variations in neurotoxicity and proteome profile of Malayan krait (Bungarus candidus) venoms. Rusmili MRA, Othman I, Abidin SAZ, Yusof FA, Ratanabanangkoon K, Chanhome L, Hodgson WC, Chaisakul J. PLoS One. 2019 Dec 30;14(12): e0227122. doi: 10.1371/journal.pone.0227122. eCollection 2019. PMID: 31887191

9. In Vitro Immunological Cross-Reactivity of Thai Polyvalent and Monovalent Antivenoms with Asian Viper Venoms. Chaisakul J, Rusmili MRA, Alsolaiss J, Albulescu LO, Harrison RA, Othman I, Casewell NR.Toxins (Basel). 2020 Dec 3;12(12):E766. doi: 10.3390/toxins12120766

Working experience: 

2005-2008: Lecturer in Pharmacology, Department of Pharmacology, Phramongkutklao College of Medicine, Bangkok, Thailand

2009-2013: Ph.D. candidate, Department of Pharmacology, Monash University, Clayton, Australia

2014-2016: Lecturer in Pharmacology, Department of Pharmacology, Phramongkutklao College of Medicine, Bangkok, Thailand

2017-Present: Assistant Professor, Department of Pharmacology, Phramongkutklao College of Medicine, Bangkok, Thailand 2018-2019: Visiting researcher (Newton fund researcher link award), Centre for Snakebite Research & Interventions, Liverpool School of Tropical Medicine (LSTM), Liverpool, United Kingdom.