Publications

Yoonsuk Lee, Yun Young Lee, Jinyoung Park, Donghyuk Seo, Rhim Ryoo, Se-Na Kim, Juwon Park, Wooram Park, Young Bin Choy, Chun Gwon Park, Ki Hyun Kim, Wonhwa Lee

Illudin S Inhibits p53-Mdm2 Interaction for Anticancer Efficacy in Colorectal Cancer 

(†Corresponding Author). 

Sanjita Paudel, Hyunchae Sim, Chai Won Park, Anyae Na, Eun Ki Min, Ki-Tae Kim, Wonhwa Lee, Sangkyu Lee

A novel toxic mechanism of formaldehyde-induced liver injury via ferroptosis through proteo-metabolomic analysis 

(†Corresponding Author). 

Hyelim Kim, Hee Ho Park, Hong Nam Kim, Donghyuk Seo, Kyung Soo Hong, Jong Geol Jang, Eun U Seo, In-Young Kim, So-Young Jeon, Boram Son, Seong-Woo Cho, Wantae Kim, June Hong Ahn, Wonhwa Lee

TOX-RAGE axis as an inflammatory mediator in severe pulmonary infectious diseases

(†Corresponding Author). 

Hyelim Kim, Han Sol Lee, Tae-Wan Kwon, Donghyuk Seo, So-Yeol Yoo, Sang Kyum Kim, Hee Ho Park, June Hong Ahn, Wonhwa Lee, Jae-Young Lee, and Hong Nam Kim 

Protection of blood vessels and promotion of anti-cancer effect in hepatocellular carcinoma via targeted delivery of doxorubicin

(†Corresponding Author). 

Seon Ah Baek, Hyelim Kim, Donghyuk Seo, Young Suk Yu, Jungbum Kim, Chai Won Park, Jaemin Kim, Dongchan Kim, Dong-Yeop Shin, Hong Nam Kim, June Hong Ahn, Sung Hee Baek, and Wonhwa Lee

Resolution of Aging-Related ARDS via Upstream Stimulatory Factor 1-Mediated Myeloid Cell Differentiation and Phagocytosis

(†Corresponding Author). 

Gyu Yong Song, Wantae Kim, Hyelim Kim, Jungbum Kim, Sang-Ah Lee, Jong Geol Jang, June Hong Ahn, Hong Nam Kim, and Wonhwa Lee

Association of Hypertension-Related Biomarkers with COVID-19 Severity and Prognosis

(†Corresponding Author). 

Hyun-Jin Kwon , Ji Eun Shin, Amir Khan, Jiyoung Kim, Jee-Young Lee, Doohyun Lee, Seungyeon Lee, Chun Young IM, Ye Ri Han, Heegyum Moon, Takesho Inukai, Koshi Akahane, Hyelim Kim, Hong Nam Kim, Wonhwa Lee , Sung-Min Ahn, Hyun Woo Park, Dong-Wook Kim

KF1601, a dual inhibitor of BCR::ABL1 and FLT3, overcomes drug resistance in FLT3+ blast phase chronic myelogenous leukemia

[2024, Total : 0, Corresponding author : 2, Co-author : 2]

1)  Kyungtae Park*, Sungwon Jung*, Hye-Jin Lee*, Hyangsu Nam, Sungeun Heo, Yoogyeong Oh, Chai Won Park, Jungbum Kim, June Hong Ahn, Jong Bum Lee, Patrick T.J. Hwang, Michiya Matsusaki, Sangmin Lee†, Wonhwa Lee†, and Jinkee Hong†. 

Nitric oxide-assisted mucus-walking zwitterionic nanocomplexes for synergistic treatment of severe respiratory infectious disease. 

Materials Today. 2024. January, 72:57-70. (†Corresponding Author) (IF: 26.943)

2) Woojin Choi, Moonhyun Choi, Taesuk Jun, Yongwoo Kim, Du Yeol Ryu, Nam Kyun Kim, Hye-Jin Lee, Seung Hyun Lee, Wonhwa Lee, Milae Lee, Keonwook Kang, Jae-Sung Kwon, Jong Geol Jang, Hojin Ha, Jae Young Choi, Sungmin Lim, Sangmin Lee, Se Yong Jung, and Jinkee Hong. 

Templated Assembly of Silk Fibroin for a Bio-feedstock-derived Heart Valve Leaflet. 

Advanced Functional Materials. 2024 April 03, 34, 2307106 (2024). (IF: 19.924)

[Featured as a front cover image] 

3) Jungbum Kim*, Hui-Ji Choi*, Donghyuk Seo, Sang-Ah Lee, Jong Beom Heo, Dong Hyuk Baek, Wonhwa Lee†, and Gyu Yong Song†

Steamed Ginseng Berry Powder ameliorates skeletal muscle atrophy via myogenic effects 

Journal of Microbiology and Biotechnology. in press.  (†Corresponding Author) (IF: 2.8)

4) Jeong Ah Park, Eunhae Park, Yein Kwon, Wonhwa Lee, June Hong Ahn, Tae-Hyung Kim, Junhong Min, Younghun Kim, Taek Lee

Synthesis of Au-decorated Boron Nitride Nanotubes and Its Application to Pretreatment-free Electrochemical Biosensor for Matrix Metalloproteinase9 in Clinical Sample 

Sensors and Actuators B: Chemical. 2024 January 15, 399:134876. (IF: 8.2)    

[2023, Total : 4, Corresponding author : 2, Co-author : 2] 

1) Eunji Sung, Hyun Chae Sim, Young-Chang Cho, Wonhwa Lee, Jong-Sup Bae, Minjia Tan, and Sangkyu Lee 

Global Profiling of Lysine Acetylation and Lactylation in Kupffer Cells

Journal of Proteome Research.  2023. October 28. 22(12): 3683–3691. (IF: 4.4) 

2) Hye-Jin Lee*, Hui-Ji Choi*, Sang-Ah Lee, Dong Hyuk Baek, Jong Beom Heo, Gyu Yong Song†, Wonhwa Lee†

Myogenesis Effects of RGX365 to Improve Skeletal Muscle Atrophy

Nutrients. 2023. October 9. 15(19): 4307. (†Corresponding Author). (IF: 5.9) 

3) Joon-Ha Park*, Chi-Pin James Wang*, Hye-Jin Lee*, Kyung Soo Hong, Jung Hong Ahn, Yeon-Woo Cho, Jeong-Hyeon Lee, Hee Seung Seo, Wooram Park, Se-Na Kim, Chun Gwon Park†, Wonhwa Lee†, and Tae-Hyung Kim† 

Uniform Gold Nanostructure Formation via Weakly Adsorbed Gold Films and Thermal Annealing for Reliable Localized Surface Plasmon Resonance-Based Detection of DNase-I.

Small. 2023. September 27. 19(39): 2302023 (†Corresponding Author). (IF: 15.153) 

4)   Jae Woon Son, Jong Mun Son, Ki Ho Hur, Wonhwa Lee, Im-Sook Song, Dong Hee Na. 

Application of isothermal chemical denaturation to early-stage formulation development of fibrinogen. 

Bulletin of the Korean Chemical Society. 2023. April. 44(4): 348-352  (IF: 1.27)

[2022, Total : 11, First author : 1, Corresponding author : 7, Co-author : 3]

1) Deokjae Heo, Sungwon Jung, Jungbum Kim, Hyungseok Yong, Sohyeon Park, Dongchang Kim, Seoungeun Cho, Kyunghwan Cha, Hanwook Ryu, Youngho Jin, Wonhwa Lee†, Sangmin Lee†, and Jinkee Hong†. 

Human activity-driven self-powered hair follicle stimulation system. 

Nano Energy. 2022. December 1. 87 Part A: 107772 (†Corresponding Author). (IF: 19.069) 

2) Woojin Choi, Hyelim Kim, Taesuk Jun, Se Yong Jung, Du Yeol Ryu, Jae-Sung Kwon, Jihee Kim†, Wonhwa Lee†, and Jinkee Hong†.

Double-action Disinfection with Silk Fibroin Gauze: Reliable Therapeutics to Prevent the Infectious Complications.

ACS Materials Letters. 2022 November 7. 4(11): 2219-2232 (†Corresponding Author). (IF: 11.170) 

3)  Hyelim Kim, Boram Son, Eun U Seo, Miji Kwon, June Hong Ahn, Heungsoo Shin, Gyu Yong Song, Eun Ji Park, Dong Hee Na, Seung-Woo Cho, Hong Nam Kim†, Hee Ho Park†, and Wonhwa Lee†. 

Cleavage-responsive biofactory T cells suppress infectious diseases-associated hypercytokinemia. 

Advanced science. 2022. September 15. 9(26):2201883 (†Corresponding Author). (IF: 17.521)

[Featured as a cover image] 

4) Chun Gwon Park, Wonhwa Lee, Dong-Hyun Kim, Fanggyuan Li, Wooram Park.

Editorial: Advanced nanotechnology for reactive oxygen species-mediated therapies

Frontiers in Molecular Biosciences. 2022. August 19. 9: 1000113. (IF: 6.113)

5) Soo Hyun Kim, Han Ju Yoo, Eun Ji Park, Wonhwa Lee, Dong Hee Na.

Impact of buffer concentration on the thermal stability of immunoglobulin G.

Journal of Pharmaceutical Investigation. 2022. July 26. 52: 739-747 (IF: 5.78)

6)  Nayeon Kim, CheLynn Jeon, Chaeyeong Kim, Soo Ho Ryu, Wonhwa Lee†, and Jong‑Sup Bae†. 

Inhibition of factor Xa activity, platelet aggregation, and experimentally induced thrombosis by Sparstolonin B. 

Phytomedicine. 2022. May 01. 99: 153987 (†Corresponding Author). (IF: 6.656)

7)  Chaeyeong Kim, Soo Ho Ryu, Nayeon Kim, Wonhwa Lee†, and Jong‑Sup Bae†. 

Renal Protective Effects of Sparstolonin B in a Mouse Model of Sepsis. 

Biotechnology and Bioprocess Engineering. 2022. April 22. 27:157-162. (†Corresponding Author). (IF: 3.386)

8)  Wonbeak Yoo*, Wonhwa Lee*, Hong Nam Kim*, Jiyoung Jeong, Hee Ho Park, Dana Jung, June Hong Ahn, Juheon Lee, Ji-Su Kim, Seung Whan Lee, Wan-Seob Cho and Seokho Kim. 

Nanodiamond as a cytokine sponge in infectious diseases. 

Frontiers in Bioengineering and Biotechnology. 2022. April 04. 10:862495. (*First author). (IF: 6.064) (*These authors contributed equally to this work)

9)  Soo Ho Ryu, Chaeyeong Kim, Nayeon Kim, Wonhwa Lee†, and Jong‑Sup Bae†. 

Inhibitory functions of cornuside on TGFBIp‑mediated septic responses. 

Journal of Natural Medicines. 2022. March 01. 76(2): 451-461. (†Corresponding Author). (IF: 3.192) 

10)  Nayeon Kim, Chaeyeong Kim, Soo Ho Ryu, Wonhwa Lee†, and Jong‑Sup Bae†.

Anti-Septic Functions of Cornuside against HMGB1-Mediated Severe Inflammatory Responses. 

International Journal of Molecular Sciences. 2022. February 13. 23: 2065 (†Corresponding Author). (IF: 6.208) 

11)  Woojin Choi, Deokjae Heo, Taeho Kim, Sungwon Jung, Moonhyun Choi, Jiwoong Heo, Jae- Sung Kwon, Byeong-Su Kim, Wonhwa Lee, Won-Gun Koh, Jeong Ho Cho, Sangmin Lee, and Jinkee Hong. 

Stress Dissipation Encoded Silk Fibroin Electrode for the Athlete-beneficial Silk Bioelectronics. 

Advanced Science. 2022. March 15. 9(8): 2105420 (IF: 17.521)

[Featured as a cover image]  

[2021, Total : 10, First author : 5, Corresponding author : 4, Co-author : 1]

1)   Hyungseok Yong, Sungwon Jung, Deokjae Heo, Woojin Choi, Jihoon Chung, Seongeun Cho, Patrick Hwang, Hyeonhui Song, Won-gun Koh, Wonhwa Lee†, Sangmin Lee†, Jinkee Hong†.

Body-mediated energy loss conversion for personalized cell vitalization. 

Nano Energy. 2021. September. 87:106209 (†Corresponding Author). (IF: 19.069)

2) Wonhwa Lee*, Jae-Young Lee*, Han Sol Lee, Youngbum Yoo, Hyosoo Shin, Hyelim Kim, Do Sik Min, Jong-Sup Bae, and Young-Kyo Seo. 

Thermosensitive Hydrogel Harboring CD146/IGF-1 Nanoparticles for Skeletal-Muscle Regeneration. 

ACS Applied Bio Materials. 2021. August 23. 4(9):7070–7080  (*First author). (IF:) (*These authors contributed equally to this work)

3)  Wonhwa Lee*, Hyunchae Sim*, Yoon-Jung Choi, Ju Young Seo, Mi-Young Yun, Gyu Yong Song, and Jong-Sup Bae. 

The Decursin Analog, CYJ-27, Suppresses Inflammation Via the Downregulation of NF-κB and STAT-1. 

Journal of Medicinal Food. 2021. August 17. 24(8):852–859 (*First author). (IF: 2.542) (*These authors contributed equally to this work)

4)  Hyelim Kim, Han Sol Lee, June Hong Ahn, Kyung Soo Hong, Jong Geol Jang, Jiseon An, Yong-Hyeon Mun, So-Yeol Yoo, Yoon Jung Choi, Mi-Young Yun, Gyu Yong Song, Jinmyoung Joo, Dong Hee Na†, Hong Nam Kim†, Hee Ho Park†, Jae-Young Lee†, Wonhwa Lee†. 

Lung-selective 25-hydroxycholesterol nanotherapeutics as a suppressor of COVID-19-associated cytokine storm. 

Nano Today. 2021. June 22. 38: 101149 (†Corresponding Author). (IF: 18.962)

5)  Hyunchae Sim*, Wonhwa Lee*, Samyeol Choo, Eui Kyun Park, Moon-Chang Baek, In-kyu Lee, Dong Ho Park,  Jong-Sup Bae. 

Sulforaphane Alleviates Particulate Matter-Induced Oxidative Stress in Human Retinal Pigment Epithelial Cells. 

Frontiers in Medicine. 2021. June 17. 8:685032 (*First author). (IF: 5.058) (*These authors contributed equally to this work)

6)  Hee Ho Park, Hyelim Kim, Han Sol Lee, Eun U Seo, Ji-Eun Kim, Jee-Hyun Lee, Yong-Hyeon Mun, So-Yeol Yoo, Jiseon An, Mi-Young Yun, Nae-Won Kang, Dae-Duk Kim, Dong Hee Na, Kyung Soo Hong, Jong Geol Jang, June Hong Ahn, Jong-Sup Bae†, Gyu Yong Song†, Jae-Young Lee†, Hong Nam Kim†, Wonhwa Lee† 

PEGylated Nanoparticle Albumin-Bound Steroidal Ginsenoside Derivatives Ameliorate SARS-CoV-2-Mediated Hyper-Inflammatory Responses. 

Biomaterials. 2021. June. 273:120827 (†Corresponding Author). (IF: 15.304)

7)  Wonhwa Lee*, Samyeol Choo, Hyunchae Sim, Jong-Sup Bae. 

Inhibitory Activities of Ononin on Particulate Matter-induced Oxidative Stress. 

Biotechnology and Bioprocess Engineering. 2021. May 06. 26: 208-215 (*First author). (IF: 3.386) (*These authors contributed equally to this work)

8)  Wonhwa Lee*, Sae-Kwang Ku*, Tae In Kim, Eun-Nam Kim, Eui Kyun Park, Gil-Saeng Jeong, Jong-Sup Bae. 

Inhibitory effects of cudratricusxanthone O on particulate matter-induced pulmonary injury. 

International Journal of Environmental Health Research. 2021. March 01. 31 (3): 271-284 (*First author). (IF: 4.477) (*These authors contributed equally to this work)

9)  Han Sol Lee, Nae-Won Kang, Hyelim Kim, Dong Hyun Kim, Jung-woo Chae, Wonhwa Lee, Gyu Yong Song, Cheong-Weon Cho, Dae-Duk Kim, Jae-Young Lee. 

Chondroitin sulfate-hybridized zein nanoparticles for tumor-targeted delivery of docetaxel. 

Carbohydrate Polymers. 2021. Februray 1. 253: 117187 (IF: 10.723)

10)  Yun Young Lee, Hee Ho Park, Wooram Park, Hyelim Kim, Jong Geol Jang, Kyung Soo Hong, Jae-Young Lee, Hee Seung Seo, Dong Hee Na, Tae-Hyung Kim, Young Bin Choy, June Hong Ahn†, Wonhwa Lee†, Chun Gwon Park†. 

Long-acting Nanoparticulate DNase-1 for Effective Suppression of SARS-CoV-2-mediated Neutrophil Activities and Cytokine Storm. 

Biomaterials. 2021. January. 267:120389 (†Corresponding Author). (IF: 15.304)

[2020, Total : 18, First author : 6, Corresponding author : 9, Co-author : 3]

1)  Hee Ho Park, Wooram Park, Yun Young Lee, Hyelim Kim, Dong Wook Choi, Ho-Keun Kwon, Dong Hee Na, Tae-Hyung Kim, Young Bin Choy, June Hong Ahn†, Wonhwa Lee†, Chun Gwon Park†. 

Bioinspired DNase-I-coated melanin-like nanospheres for modulation of infection-associated NETosis dysregulation. 

Advanced Science. 2020. December 02. 7(23):2001940 (Corresponding Author). (IF: 16.806)

[Featured as a cover image]  

2)  Eun Young Choi, Hee Ho Park, Hyelim Kim, Hong Nam Kim, Inyoung Kim, Soyoung Jeon, Wantae Kim†, Jong-Sup Bae†, Wonhwa Lee†. 

Wnt5a and Wnt11 as acute respiratory distress syndrome biomarkers for SARS-CoV-2 patients. 

European Respiratory Journal. 2020. November 26. 56(5): 2001531 (†Corresponding Author). (IF: 16.671)

3)  Hee Ho Park, Hong Nam Kim, Wonhee Lim, Kyung Soo Hong, June Hong Ahn, Jong Geol Jang†, Jong-Sup Bae†, Wonhwa Lee†. 

Ferritin Nanocage-based Methyltransferase SETD6 for severe COVID-19 therapy. 

Advanced Functional materials. 2020. November 25. 30(48): 2006110 (†Corresponding Author). (IF: 18.808)

4)  Wonhwa Lee*, Hui-Ji Choi*, Hyunchae Sim*, Samyeol Choo, Gyu Yong Song, Jong-Sup Bae. 

Barrier protective functions of hederacolchiside-E against HMGB1-mediated septic responses. 

Pharmacological Research. 2020. November 24. 163: 105318 (*First author). (IF:7.658) (*These authors contributed equally to this work)

5)  June Hong Ahn, Jong Geol Jang, Kyung Soo Hong, Jong Ho Lee, Hong Nam Kim†, Dongha Kim†, Wonhwa Lee†. 

GSK-LSD1, a LSD1 Inhibitor, Quashes SARS-CoV-2-triggered Cytokine Release Syndrome in vitro. 

Signal Transduction and Targeted Therapy 2020. November 17. 5(1):267. (†Corresponding Author). (IF: 18.187)

6)  Wonhwa Lee*, Dongyup Hahn*, Hyunchae Sim, Samyeol Choo, Sangkyu Lee, Taeho Lee, and Jong-Sup Bae. 

Inhibitory functions of cardamonin against particulate matter-induced lung injury through TLR4-mTOR-autophagy pathways. 

Fitoterapia. 2020. September 15. 146: 104724 (*First author). (IF: 2.882) (*These authors contributed equally to this work)

7)  Wonhwa Lee*, June Hong Ahn*, Hee Ho Park*, Hong Nam Kim*, Hyelim Kim, Youngbum Yoo, Hyosoo Shin, Kyung Soo Hong, Jong Geol Jang, Chun Gwon Park, Eun Young Choi, Jong-Sup Bae, Young-Kyo Seo. 

COVID-19-activated SREBP2 disturbs cholesterol biosynthesis and leads to cytokine storm. 

Signal Transduction and Targeted Therapy. 2020. September 3. 5(1): 186 (*First author). (IF: 18.187) (*These authors contributed equally to this work)

8)  Hee Ho Park, Hong Nam Kim, Hyelim Kim, Youngbum Yoo, Hyosoo Shin, Eun Young Choi†, Jong-Sup Bae†, Wonhwa Lee†. 

Acetylated K676 TGFBIp as a severity diagnostic blood biomarker for SARS-CoV-2 pneumonia. 

Science Advances 2020. July. 31. 6(31), eabc1564. (†Corresponding Author). (IF: 14.136)

9)  Min-Hwan Kim, Dong Hyun Kim, Duy-Thuc Nguyen, Han Sol Lee, Nae-Won Kang, Min-Jun Baek, Jiseon An, So-Yeol Yoo, Yong-Hyeon Mun, Wonhwa Lee, Ki-Taek Kim, Cheong-Weon Cho, Jae-Young Lee, Dae-Duk Kim. 

Preparation and Evaluation of Eudragit L100-PEG Proliponiosomes for Enhanced Oral Delivery of Celecoxib. 

Pharmaceutics. 2020. July. 30. 12(8), 718. (IF: 6.321)

10)  Wonhwa Lee†, Eun Ji Park†, Oh Kwang Kwon, Hyelim Kim, Youngbum Yoo, Shin-Woo Kim, Young-Kyo Seo, In-San Kim, Dong Hee Na†, Jong-Sup Bae†. 

Dual peptide-dendrimer conjugate inhibits acetylation of transforming growth factor β-induced protein and improves survival in sepsis. 

Biomaterials. 2020 March 28. 246:120000 (First and Corresponding Author). (IF: 12.479)

11)  Jong Geol Jang, Jian Hur, Kwan Ho Lee, Jin Hong Chung, Kyeong-Cheol Shin, Eun Young Choi, Hyun Jung Jin, Kyung Soo Hong, Wonhwa Lee†, June Hong Ahn†. 

Prognostic accuracy of the SIRS, qSOFA, and NEWS for early detection of clinical deterioration in SARS-CoV-2 infected patients. 

Journal of Korean Medical Science. 2020. June 29. 35(25): e234 (†Corresponding Author). (IF:2.153)

12)  Seyoung Hong, Dong Wook Choi, Hong Nam Kim, Chun Gwon Park†, Wonhwa Lee†, Hee Ho Park† 

Protein-based nanoparticles as drug delivery systems. 

Pharmaceutics. 2020. June 29. 12(7): 604 (†Corresponding Author). (IF: 6.321)

13)  Jong Geol Jang, Jian Hur, Eun Young Choi, Wonhwa Lee†, June Hong Ahn†. 

Prognostic factors for severe coronavirus disease 2019 in Daegu, Korea. 

Journal of Korean Medical Science. 2020. June. 15. 35(23):e209 (†Corresponding Author). (IF:2.153)

14)  InWha Park*, Wonhwa Lee*, Youngbum Yoo, Hyosoo Shin, Joonseok Oh, Hyelim Kim, Mi-Ae Kim, Jae Sam Hwang, Jong-Sup Bae, MinKyun Na. 

Tetrahydroquinolines from the edible insect Allomyrina dichotoma modulate vascular inflammatory responses in LPS-mediated human endothelial cells. 

International Journal of Molecular Sciences. 2020. May. 12. 21(10): 3406 (*First author). (IF: 5.923) (*These authors contributed equally to this work)

15)  Kyung Soo Hong, Kwan Ho Lee, Jin Hong Chung, Kyeong-Cheol Shin, Eun Young Choi, Hyun Jung Jin, Jong Geol Jang, Wonhwa Lee, and June Hong Ahn. 

Clinical Features and Outcomes of 98 Patients Hospitalized with SARS-CoV-2 Infection in Daegu, South Korea: A Brief Descriptive Study. 

Yonsei Medical Journal. 2020 May. 61(5):431-437 (IF:2.759)

16)  Wonhwa Lee*, Hayeong Lee, Eui Kyun Park, and Jong-Sup Bae. 

Inhibitory functions of maslinic acid, a natural triterpene, on HMGB1-mediated septic responses. 

Phytomedicine. 2020. Apri 01. 69: 153200. (*First author). (IF: 5.340)

17)  Wonhwa Lee*, Moon-Chang Baek, Kyung-Min Kim and Jong-Sup Bae. 

Biapenem as a Novel Insight into Drug Repositioning against Particulate Matter-Induced Lung Injury. 

International Journal of Molecular Sciences. 2020. Feburary 21. 21(4):1462 (*First author). (IF: 5.923)

18)  Wonhwa Lee*, Jaehong Kim, Eui Kyun Park, and Jong-Sup Bae. 

Maslinic acid ameliorates inflammation via the downregulation of NF- kB and STAT-1. 

Antioxidants (Basel). 2020. January 25. 9 (2): 106. (*First author). (IF: 6.312)

[2019, Total : 14, First author : 14]

1)  Wonhwa Lee*, Gil-Saeng Jeong, Moon-Chang Baek, Sea-Kwang Ku, and Jong-Sup Bae. 

Renal protective effects of aloin in a mouse model of sepsis. 

Food and Chemical Toxicology. 2019. October. 01. 132:110651. (*First author). (IF: 6.023)

2)  Hyukjae Choi*, Wonhwa Lee*, Eonmi Kim, Sae-Kwang Ku, and Jong-Sup Bae. 

Inhibitory effects of collismycin C and pyrisulfoxin A on particulate matter-induced pulmonary injury. 

Phytomedicine. 2019. September 01. 62. 152939. (*First author). (IF: 5.340) (*These authors contributed equally to this work)

3)  Wonhwa Lee*, Sae-Kwang Ku, Ji-Eun Kim, Soo-Hyun Cho, Gyu-Yong Song, Jong-Sup Bae.

Inhibitory effects of black ginseng extract on particulate matter-induced pulmonary injury. 

American Journal of Chinese Medicine. 2019. September. 1. 47(6):1237-1251. (*First author). (IF: 4.667)

4)  Wonhwa Lee*, So Yeon Jeong, Myeong Ju Gu, Ji Sun Lim, Eui Kyun Park, MoonChang Baek, Jong-Sang Kim, Dongyup Hahn, Jong-Sup Bae. 

Inhibitory effects of compounds isolated from Dioscorea batatas Decne peel on particulate matter-induced pulmonary injury in mice. 

Journal of Toxicology and Environmental Health, Part A. 2019. July 25. 82(12):727-740. (*First author). (IF: 2.882)

5)  InWha Park*, Wonhwa Lee*, Hyelim Kim, Khong Trong Quan, DaYoung Kim, Jong-Sup Bae, MinKyun Na. 

Antithrombotic and Antiplatelet Activities of New Isohopane Triterpene From the Roots of Rubia akane. 

Natural Product Communications. 2019. July 15. 14 (7): 1-6. (*First author). (IF: 0.986) (*These authors contributed equally to this work)

6)  Wonhwa Lee*, Sae-Kwang Ku*, Ji-Eun Kim*, Ga-Eun Choi, Gyu-Yong Song, Jong-Sup Bae. 

Pulmonary Protective Functions of Rare Ginsenoside Rg4 on Particulate Matter-induced Inflammatory Responses. 

Biotechnology and Bioprocess Engineering. 2019. June 01. 24: 445-453. (*First author). (IF: 2.836) (*These authors contributed equally to this work)

7)  Wonhwa Lee, and Jong‐Sup Bae. 

Inhibitory effects of Kyung-Ok-Ko, traditional herbal prescription, on particulate matter-induced vascular barrier disruptive responses. 

International Journal of Environmental Health Research. 2019 June 01. 29(3):301-311. (*First author). (IF: 3.411)

8)  Wonhwa Lee*, Sae-Kwang Ku*, Ji-Eun Kim, Soo-Hyun Cho, Gyu-Yong Song, and Jong-Sup Bae. 

Inhibitory effects of protopanaxatriol type ginsenoside fraction (Rgx365) on particulate matter-induced pulmonary injury. 

Journal of Toxicology and Environmental Health, Part A. 2019. May 01. 82 (5): 338-350. (*First author). (IF: 2.882) (*These authors contributed equally to this work)

9)  Sumin Yang*, Wonhwa Lee*, Bong-Seon Lee, Changhun Lee, Eui Kyun Park, Sae-Kwang Ku, and Jong-Sup Bae. 

Aloin Reduces HMGB1 Mediated Septic Responses and Improves Survival in Septic Mice by Activation of the SIRT1 and PI3K/Nrf2/HO1 Signaling Axis. 

American Journal of Chinese Medicine. 2019. May 01. 47(3): 613-633. . (*First author). (IF: 4.667) (*These authors contributed equally to this work)

10)  Wonhwa Lee*, Yuseok O*, Changhun Lee, So Yeon Jeong, Jee-Hyun Lee, Moon-Chang Baek, Gyu-Yong Song,  Jong-Sup Bae. 

Suppressive activities of KC1-3 on HMGB1-mediated septic responses. 

Biochemical Pharmacology. 2019. May 01. 163:260-268. (*First author). (IF: 5.858) (*These authors contributed equally to this work)

11)  Wonhwa Lee*, O Yuseok*, Sumin Yang, Bong‐Seon Lee, Jee‐Hyun Lee, Eui Kyun Park, Moon‐Chang Baek, Gyu‐Yong Song, and Jong‐Sup Bae. 

JH-4 reduces HMGB1-mediated septic responses and improves survival rate in septic mice. 

Journal of Cellular Biochemistry. 2019. April 01. 120:6277-6289. (*First author). (IF: 4.429) (*These authors contributed equally to this work)

12)  Wonhwa Lee*, Sumin Yang*, Changhun Lee, Eui Kyun Park, Kyung-Min Kim, Sae-Kwang Ku, and Jong-Sup Bae. 

Aloin reduces inflammatory gene iNOS via inhibition activity and p-STAT-1 and NF-κB. 

Food and Chemical Toxicology. 2019 April 01. 126: 67-71. (*First author). (IF: 6.023) (*These authors contributed equally to this work)

13)  Ji-Eun Kim*, Wonhwa Lee*, Sumin Yang, Soo-Hyun Cho, Moon-Chang Baek, Gyu-Yong Song, and Jong-Sup Bae. 

Suppressive effects of rare ginsenosides, Rk1 and Rg5, on HMGB1-mediated septic responses. 

Food and Chemical Toxicology. 2019. February 01. 124: 45-53. (*First author). (IF: 6.023) (*These authors contributed equally to this work)

14)  Wonhwa Lee*, Soo-Hyun Cho*, Ji-Eun Kim, Changhun Lee, Jee-Hyun Lee, Moon-Chang Baek, Gyu-Yong Song and Jong-Sup Bae. 

Suppressive effects of ginsenoside Rh1 on HMGB1-mediated septic responses. 

American Journal of Chinese Medicine. 2019. January 9. 47(1): 119-133. (*First author). (IF: 4.667) (*These authors contributed equally to this work)

[2018, Total : 8, First author : 6, Corresponding author : 1]

1)  Wonhwa Lee*, Seung-Yoon Park, Youngbum Yoo, Soon-Young Kim, Jung-Eun Kim, Shin-Woo Kim, Young-Kyo Seo, Eui Kyun Park, In-San Kim, and Jong-Sup Bae. 

Macrophagic stabilin-1 restored disruption of vascular integrity caused by sepsis. 

Thrombosis and Haemostasis. 2018. October 01. 118 (10): 1776-1789 (*First author). (IF: 5.249)

2) Yuri Lee, Gil-Saeng Jeong, Kyung-Min Kim, Wonhwa Lee†, and Jong-Sup Bae†. 

Cudratricusxanthone A attenuates sepsis-induced liver injury via SIRT1 signaling. 

Journal of Cellular Physiology. 2018. July 01. 233 (7): 5441-5446. (†Corresponding Author). (IF:6.384)

3)  Yuri Lee*, Wonhwa Lee*, Hyun-Ha Chang, Shin-Woo Kim, Jaehong Kim, and Jong-Sup Bae. 

Testican-1, as a novel early diagnosis of sepsis. 

Journal of Cellular Biochemistry. 2018. May 01. 119(5): 4216-4223. (*First author). (IF: 6.384) (*These authors contributed equally to this work)

4)  Wonhwa Lee*, Doohyun Lee*, Yuri Lee, Taeho Lee, Kyung-Sik Song, Eun-Ju Yang, and Jong-Sup Bae. 

Isolation, Synthesis, and Antisepsis Effects of a C-Methylcoumarinochromone Isolated from Abronia nana Cell Culture. 

Journal of Natural Products. 2018. May 25. 81 (5): 1173-1182. (*First author). (IF: 4.050) (*These authors contributed equally to this work)

5)  Dongha Kim, Hye Jin Nam, Wonhwa Lee, Hwa Young Yim, Jun-Yeong Ahn, Se Won Park, Hi-Jai R. Shin, Reynold Yu, Kyoung-Jae Won, Jong-Sup Bae, Keun Il Kim, and Sung Hee Baek.

PKCα-LSD1-NF-κB Signaling Cascade Is Crucial for Epigenetic Control of the Inflammatory Response. 

Molecular cell. 2018. February 01. 69: 398-411. (IF: 17.970)

6)  Yuri Lee*, Wonhwa Lee*, Jaehong Kim, and Jong-Sup Bae. 

Inhibitory effect of sulforaphane on secretory group IIA phospholipase A2. 

International Journal of Pharmacology. 2018. February 01. 14 (2): 187-193. (*First author). (IF: 0.751) (*These authors contributed equally to this work)

7)  Wonhwa Lee*, Mi-Hye Hwang*, Yuri Lee and Jong-Sup Bae. 

Protective effects of zingerone on lipopolysaccharide-induced hepatic failure through the modulation of inflammatory pathways. 

Chemico-Biological Interactions. 2018. February 01. 281: 106-110. (*First author). (IF: 5.192) (*These authors contributed equally to this work)

8)  Wonhwa Lee*, Yuri Lee*, Jaehong Kim and Jong-Sup Bae. 

Protective Effects of Pelargonidin on Lipopolysaccharide-induced Hepatic Failure. 

Natural Product Communications. 2018. January 01. 13 (1): 45-48. (*First author). (IF: 0.986) (*These authors contributed equally to this work)

[2017, Total : 9, First author : 9]

1)  Wonhwa Lee*, Suyeon Lee, Joonhyeok Choi, Jun-Hyeong Park, Kyung-Min Kim, Jun-Goo Jee, and Jong-Sup Bae. 

Antithrombotic properties of JJ1, a potent and novel thrombin inhibitor. 

Scientific Reports. 2017. November 01. 7:14862. (*First author). (IF: 4.379)

2)  Wonhwa Lee*, Mi-Ae Kim*, In Wha Park*, Jae Sam Hwang, Min Kyun Na, and Jong-Sup Bae. 

Novel direct factor Xa inhibitory compounds from Tenebrio molitor with anti-platelet aggregation activity. 

Food Chemistry and Toxicology. 2017. November 01. 109: 19-27. (*First author). (IF: 6.023) (*These authors contributed equally to this work)

3)  Wonhwa Lee*, Eun Ji Park*, Gahee Min, Joonhyeok Choi, Dong Hee Na, and Jong-Sup Bae. 

Dual functioned PEGylated phospholipid micelles containing cationic antimicrobial decapeptide for treating sepsis. 

Theranostics. 2017. August 23. 7(15): 3759-3767. (*First author). (IF: 11.556) (*These authors contributed equally to this work)

4)  Wonhwa Lee*, HeeSeung Lee*, Mi-Ae Kim, Joonhyeok Choi, Kyung-Min Kim, Jae Sam Hwang, Min-Kyun Na, and Jong-Sup Bae. 

Evaluation of novel factor Xa inhibitors from Oxya chinensis sinuosa with anti-platelet aggregation activity. 

Scientific Reports. 2017. August 11. 7:7934. (*First author). (IF: 4.379) (*These authors contributed equally to this work)

5)  Wonhwa Lee*, Sae-Kwang Ku*, and Jong-Sup Bae. 

Zingerone reduces HMGB1-mediated septic responses and improves survival in septic mice. 

Toxicology and Applied Pharmacology. 2017. August 15. 329: 202-211. (*First author). (IF: 4.219) (*These authors contributed equally to this work)

6)  Wonhwa Lee*, Yuri Lee, Gil-Saeng Jeong, Sae-Kwang Ku, and Jong-Sup Bae. 

Cudratricusxanthone A attenuates renal injury in septic mice. 

Food and Chemical Toxicology. 2017. August 01. 106: 404-410. (*First author). (IF: 6.023)

7)  Wonhwa Lee*, Sae-Kwang Ku*, Mi-Ae Kim, Jong-Sup Bae. 

Anti-factor Xa activities of zingerone with anti-platelet aggregation activity. 

Food and Chemical Toxicology. 2017. July 1. 105: 186-193. (*First author). (IF: 6.023) (*These authors contributed equally to this work)

8)  Soo Hyun Lee*, Wonhwa Lee*, Nguyen Thi Ha, Il Soo Um, Jong-Sup Bae, and Eunsook Ma. 

Synthesis and Thrombin, Factor Xa and U46619 Inhibitory Effects of Non-amidino and Amidino N2-Thiophenecarbonyl- and N2-Tosylanthranilamides. 

International Journal of Molecular Sciences. 2017. June 1. 18 (6): 1144. (*First author). (IF: 5.923) (*These authors contributed equally to this work)

9)  Jung In Lee*, Wonhwa Lee*, Mi-Ae Kim, Jae Sam Hwang, MinKyun Na, and Jong-Sup Bae. 

Inhibition of platelet aggregation and thrombosis by indole alkaloids isolated from the edible Protaetia brevitarsis seulensis (Kolbe). 

Journal of Cellular and Molecular Medicine. 2017. June 1. 21 (6): 1217-1227. (*First author). (IF: 5.310) (*These authors contributed equally to this work)

[2016, Total : 9, First author : 7]

1)  Wonhwa Lee*, Sae-Kwang Ku*, Songhee Park, Kyung-Min Kim, Hyukjae Choi, and Jong-Sup Bae. 

Inhibitory effect of three diketopiperazines from marine-derived bacteria on HMGB1-induced septic responses in vitro and in vivo. 

American Journal of Chinese Medicine. 2016. October 01. 44(6). 1145-1166. (*First author). (IF: 4.667) (*These authors contributed equally to this work)

2)  Eun-Ju Yang*, Wonhwa Lee*, Kyung-Sik Song, and Jong-Sup Bae. 

Ameliorative effect of a rarely occurring C-methylrotenoid on HMGB1-induced septic responses in vitro and in vivo. 

Biochemical Pharmacology. 2016. June 15. 110-111: 58-70. (*First author). (IF: 5.858) (*These authors contributed equally to this work)

3)  Soo Hyun Lee*, Wonhwa Lee*, Jong-Sup Bae, and Eunsook Ma. 

Synthesis and in vitro and in vivo Anticoagulant and Antiplatelet Activities of Amidino- and Non-amidinobenzamides. 

Molecules. 2016. May 21. 21(5) 676. (*First author). (IF: 4.411) (*These authors contributed equally to this work)

4)  Byeongjin Jung, Hyejin Kang, Wonhwa Lee, Hyun Jin Noh, You-Sun Kim, Min-Su Han, Moon-Chang Baek, Jaehong Kim, and Jong-Sup Bae. 

Anti-septic effects of dabrafenib on HMGB1-mediated inflammatory responses. 

BMB reports. 2016.April 30. 49(4): 214-219. (IF: 4.778)

5)  Wonhwa Lee*, Sae-Kwang Ku*, Hyukjae Choi, and Jong-Sup Bae. 

Inhibitory effects of three diketopiperazines from marine-derived bacteria on endothelial protein C receptor shedding in human endothelial cells and mice. 

Fitoterapia.2016 April, 110: 181–188. (*First author). (IF: 2.882) (*These authors contributed equally to this work)

6)  Sae-Kwang Ku, Eun-Kyung Yoon, Wonhwa Lee, Sinae Kwon, Taeho Lee, and Jong-Sup Bae. 

Antithrombotic and antiplatelet activities of pelargonidin in vivo and in vitro. 

Archives of Pharmacal Research. 2016. March 31. 39 (3): 398-408. (IF: 4.946)

7)  Wonhwa Lee*, Eun Ji Park*, Soyoung Kwak, Kang Choon Lee, Dong Hee Na and Jong-Sup Bae. 

Trimeric PEG-conjugated Exendin-4 for the treatment of sepsis. 

Biomacromolecules. 2016. March 1. 17 (3): 1160-1169. (*First author). (IF: 6.092) (*These authors contributed equally to this work)

8)  Wonhwa Lee*, Jung In Lee*, Roshan Kulkarni, Hyejin Kang, Mi-Ae Kim, Jae Sam Hwang, MinKyun Na, and Jong-Sup Bae. 

Antithrombotic and antiplatelet activities of small-molecule alkaloids from Scolopendra subspinipes mutilans. 

Scientific Reports. 2016. Feb 24. 6:21956. (*First author). (IF: 4.379) (*These authors contributed equally to this work)

9)  Wonhwa Lee*, Eun-Ju Yang, Dong Ho Park, Jong-Sup Bae. 

Suppressive effects of polyozellin on endothelial protein C receptor shedding via inhibiting TACE activity and MAP kinases. 

Fitoterapia. 2016. January 1. 108: 26-32. (*First author). (IF: 2.882)

[2015, Total : 23, First author : 19]

1)  Wonhwa Lee*, Sae-Kwang Ku*, Jong-Sup Bae. 

Ameliorative effect of vicenin-2 and scolymoside on TGFBIp-induced septic responses. 

Inflammation. 2015. December. 38 (6): 2166-2177. (*First author). (IF: 4.092) (*These authors contributed equally to this work)

2)  Oh Kwang Kwon*, Wonhwa Lee*, Sun Ju Kim, Ju Yeon Lee, Jin Young Kim, Jong-Sup Bae, Sangkyu Lee. 

In-depth proteomics approach of secretome to identify novel biomarker for sepsis in LPS-stimulated endothelial cells. 

Electrophoresis. 2015. December 1. 36 (23): 2851-2858. (*First author). (IF: 3.535) (*These authors contributed equally to this work)

3)  Wonhwa Lee*, Junyoung Seo, Soyoung Kwak, EunJi Park, Dong Hee Na, Soyoun Kim, You Mie Lee, In-San Kim, Jong-Sup Bae. 

A double-chambered protein nanocage loaded with thrombin receptor agonist peptide (TRAP) and γ-carboxyglutamic acid of protein C (PC-Gla) for sepsis treatment. 

Advanced Materials. 2015. November 11. 27 (42): 6567-6643. (*First author). (IF: 30.849)

4)  Nguyen Quoc Tuan*, Wonhwa Lee*, Joonseok Oh, Roshan Rajan Kulkarni, Charlotte Gény, Byeongjin Jung, Hyejin Kang, Jong-Sup Bae, Min Kyun Na. 

Flavanones and Chromones from Salicornia herbacea Mitigate Septic Lethality via Restoring Vascular Barrier Integrity. 

Journal of Agricultural and Food Chemistry. 2015. November 25. 63 (46): 10121-10130. (*First author). (IF: 5.279) (*These authors contributed equally to this work)

5)  Roshan R Kulkarni*, Wonhwa Lee*, Tae Su Jang, Jung In Lee, Soyoung Kwak, MiSeon Park, Hyun-Shik  Lee,  Jong-Sup Bae, MinKyun Na. 

Caffeoyl Glucosides from Nandina domestica Inhibit LPS-induced Endothelial Inflammatory Responses. 

Bioorganic & Medicinal Chemistry Letters. 2015. November 15. 25: 5367-5371. (*First author). (IF: 2.823) (*These authors contributed equally to this work)

6)  Eun-Kyung Yoon, Sae-Kwang Ku, Wonhwa Lee, Soyoung Kwak, Hyejin Kang, Byeongjin Jung, Jong-Sup Bae. 

Antitcoagulant and antiplatelet activities of scolymoside. 

BMB Reports. 2015. October 31. 48 (10): 578-583. (IF: 4.778)

7)  Wonhwa Lee*, Sae-Kwang Ku*, Dong Hee Na, Jong-Sup Bae. 

Anti-inflammatory effects of lysozyme against HMGB1 in human endothelial cells and in mice. 

Inflammation. 2015. October 1. 38(5):1911-1924. (*First author). (IF: 4.092) (*These authors contributed equally to this work)

8)  Sae-Kwang Ku, Jee Hyun Lee, Yuseok O, Wonhwa Lee, Gyu-Yong Song, Jong-Sup Bae. 

Vascular barrier protective effects of 3-N- or 3-O-cinnamoyl carbazole derivatives. 

Bioorganic & Medicinal Chemistry Letters. 2015. October 1. 25 (19): 4304-4307. (IF: 2.823)

9)  Wonhwa Lee*, Kyung-Min Kim, Jong-Sup Bae. 

Ameliorative effect of aspalathin and nothofagin from rooibos (Aspalathuslinearis) on HMGB1-induced septic responses in vitro and in vivo. 

American Journal of Chinese Medicine. 2015. September 1. 43 (5): 991-1012. (*First author). (IF: 4.667) (*These authors contributed equally to this work)

10)  Eun-Ju Yang, Sae-Kwang Ku, Wonhwa Lee, Kyung-Sik Song, Jong-Sup Bae. 

Inhibitory effects of polyozellin from Polyozellus multiplex on HMGB1-mediated septic responses. 

Inflammation Research. 2015. September 1. 64 (9): 733-746. (IF: 4.575)

11)  Wonhwa Lee*, Jong-SupBae. 

Antithrombotic and antiplatelet activities of vicenin-2. 

Blood Coagulation & Fibrinolysis. 2015. September 1. 26 (6): 628-634. (*First author). (IF: 1.276)

12)  Wonhwa Lee*, Eun Kyung Yoon, Kyung-Min Kim, Dong Ho Park, Jong-Sup Bae. 

Anti-septic effect of vicenin-2 and scolymoside from Cyclopiasubternata (Honeybush) in response to HMGB1 as a late sepsis mediator in vitro and in vivo. 

Canadian Journal of Physiology and Pharmacology. 2015. August 1. 93 (8): 709-720. (*First author). (IF: 1.946)

13)  Wonhwa Lee*, Soyoung Kwak, Eunju Yun, Jee Hyun Lee, MinKyun Na, Gyu-Yong Song, Jong-Sup Bae. 

Anti-septic effects of new 3’-N-substituted carbazole derivatives in vitro and in vivo. 

Inflammation. 2015. August 1. 38(4):1649-1661. (*First author). (IF: 4.092)

14)  Wonhwa Lee*, Jong-Sup Bae. 

Anti-inflammatory effects of aspalathin and nothofagin from rooibos (Aspalathuslinearis) in vitro and in vivo. 

Inflammation. 2015. August 1. 38 (4): 1502-1516. (*First author). (IF: 4.092)

15)  Wonhwa Lee*, Oh Kwang Kwon*, Min-Su Han, You Mie Lee, Shin-Woo Kim, Kyung-Min Kim, Taeho Lee, Sangkyu Lee, Jong-Sup Bae. 

Role of moesin in HMGB1-stimulated severe inflammatory responses. 

Thrombosis and Haemostasis. 2015. July 28.114(2):350-363. (*First author). (IF: 5.249) (*These authors contributed equally to this work)

16)  Wonhwa Lee*, Jong-Sup Bae. 

Antithrombotic and antiplatelet activities of orientin in vitro and in vivo. 

Journal of Functional Foods. 2015. June 17. 17: 388-398. (*First author). (IF: 4.451)

17)  Sae-Kwang Ku, Wonhwa Lee, Min Kang, Jong-Sup Bae. 

Antithrombotic activities of aspalathin and nothofagin via inhibiting platelet aggregation and FIIa/FXa. 

Archives of Pharmacal Research. 2015. June 1. 38 (6): 1080-1089. (IF: 4.946)

18)  Wonhwa Lee*, Sae-Kwang Ku*, Jong-Sup Bae. 

Antiplatelet, anticoagulant, and profibrinolytic activities of baicalin. 

Archives of Pharmacal Research. 2015. May 1. 38 (5): 893-903. (*First author). (IF: 4.946) (*These authors contributed equally to this work)

19)  Nguyen Q. Tuan*, Wonhwa Lee*, Joonseok Oh, Soyoung Kwak, Hyun Gyu Lee, Daneel Ferreira, Jong-Sup Bae, MinKyun Na. 

Quinic acid derivatives from Salicornia herbacea alleviate HMGB1-mediated endothelial dysfunction. 

Journal of Functional Foods. 2015. May 1. 15: 326-338. (*First author). (IF: 4.451) (*These authors contributed equally to this work)

20)  Wonhwa Lee*, Eun Ji Park*, Soyoung Kwak*, Yejin Kim, Dong Hee Na, Jong-Sup Bae. 

PEGylated lysozymes with anti-septic effects in human endothelial cells and in mice. 

Biochemical and Biophysical Research Communications. 2015. April 17. 459 (4): 662-667. (*First author). (IF: 3.575) (*These authors contributed equally to this work)

21)  Wonhwa Lee*, Soyoung Kwak*, Hyun-Shik Lee, Dong Hee Na, You Mie Lee, Jong-Sup Bae. 

Inhibitory effect of exendin-4 on secretory group IIA phospholipase A2. 

Biochemical and Biophysical Research Communications. 2015. April 17. 459 (4): 650-654. (*First author). (IF: 3.575) (*These authors contributed equally to this work)

22)  Sae-Kwang Ku*, Wei Zhou*, Wonhwa Lee*, Min-Su Han, MinKyun Na, Jong-Sup Bae. 

Anti-inflammatory effects of hyperoside in human endothelial cells and in mice. 

Inflammation. 2015. April 1. 38 (2): 784-799. (*First author). (IF: 4.092) (*These authors contributed equally to this work)

23)  Wonhwa Lee*, Sae-Kwang Ku*, Jong-Sup Bae. 

Anti-inflammatory effects of baicalin, baicalein and wogonin in vitro and in vivo. 

Inflammation. 2015. February 1. 38 (1): 110-125. (*First author). (IF: 4.092) (*These authors contributed equally to this work)

[2014, Total : 14, First author : 12]

1)  Jong-Sup Bae*, Wonhwa Lee*, Hye-Nam Son, You-Mie Lee, In-San Kim Anti-TGFBIp antibody ameliorates vascular barrier dysfunction and improves survival in sepsis. Acta Physiologica. 2014. December 1. 212 (4): 306-315. (*First author). (IF: 6.311) (*These authors contributed equally to this work)

2)  Wonhwa Lee*, Sae-Kwang Ku*, Jong-Sup Bae. Factor Xa inhibits HMGB1-induced septic responses in human umbilical vein endothelial cells and in mice. Thrombosis and Haemostasis. 2014. October 1. 112 (4): 757-769. (*First author). (IF: 5.249) (*These authors contributed equally to this work)

3)  Wonhwa Lee*, Sae-Kwang Ku*, Tae Cheon Jeong, Sangkyu Lee, Jong-Sup Bae. Ginsenosides inhibit HMGB1-induced inflammatory responses in HUVECs and in murine polymicrobial sepsis. Bulletin of the Korean Chemical Society. 2014. October 1. 35 (10): 2955-2962. (*First author). (IF: 0.969) (*These authors contributed equally to this work)

4)  Wonhwa Lee*, Sae-Kwang Ku*, EunJi Park, Dong Hee Na, Kyung-Min Kim, Jong-Sup Bae. Exendin-4 inhibits HMGB1-induced inflammatory responses in HUVECs and in murine polymicrobial sepsis. Inflammation.  2014. October 1. 37 (5): 1876-1888. (*First author). (IF: 4.092) (*These authors contributed equally to this work)

5)  HayoungYoo, Sae-Kwang Ku, Wonhwa Lee, SoyoungKwak, Young-Doo Baek, Byung-Woon Min, Gil-Saeng Jeong, Jong-Sup Bae. Antiplatelet, anticoagulant, and profibrinolytic activities of cudratricusxanthone A. Archives of Pharmacal Research. 2014. August 1. 37 (8): 1069-1078. (IF: 4.946)

6)  Wonhwa Lee*, Sae-Kwang Ku*, Jong-Sup Bae. Vascular barrier protective effects of orientin and isoorientin in LPS-induced inflammation in vitro and in vivo. Vascular Pharmacology. 2014. July 1. 62 (1): 3-14. (*First author). (IF: 5.773) (*These authors contributed equally to this work)

7)  Wonhwa Lee*, HayoungYoo*, Sea-Kwang Ku*, Shin-Woo Kim and Jong-Sup Bae. Raftlin: a New Biomarker in Human Sepsis. Inflammation. 2014. June 1. 37(3): 706-711. (*First author). (IF: 4.092) (*These authors contributed equally to this work)

8)  Wei Zhou, Joonseok Oh, Wonhwa Lee, Soyoung Kwak, Wei Li, Amar G. Chittiboyina, Daneel Ferreira, Mark T. Hamann, Seung Ho Lee, Jong-Sup Bae, MinKyun Na. The First Cyclomegastigmane Rhododendroside A from Rhododendron brachycarpum Alleviates HMGB1-induced Sepsis. Biochimica et Biophysica Acta - General Subjects. 2014. June 1. 1840 (6): 2042-2049. (IF: 3.770)

9)  Wonhwa Lee*, Sae-Kwang Ku*, HayoungYoo, Kyung-Sik Song, Jong-Sup Bae. Andrographolide inhibits HMGB1-induced inflammatory responses in HUVECs and in murine polymicrobial sepsis. Acta Physiologica.  2014. May 1. 211 (1): 176-187. (*First author). (IF: 6.311) (*These authors contributed equally to this work)

10)  Wonhwa Lee*, Sae-Kwang Ku*, Shin-Woo Kim, Jong-Sup Bae. Endocan elicits severe vascular inflammatory responses in vitro and in vivo. Journal of Cellular Physiology. 2014. May 22 9(5):620-630. (*First author). (IF: 6.384) (*These authors contributed equally to this work)

11)  Jong-Sup Bae*, Wonhwa Lee*, Ju-Ock Nam, Jung-Eun Kim, Shin-Woo Kim, In-San Kim. Transforming Growth Factor β-induced Protein Promotes Severe Vascular Inflammatory Responses. American Journal of Respiratory and Critical Care Medicine. 2014. April 1. 189(7):779-786. (*First author). (IF: 21.405) (*These authors contributed equally to this work)

12)  Wonhwa Lee*, Sae-Kwang Ku*, Doohyun Lee, Taeho Lee, Jong-Sup Bae. Emodin-6-O-β-D-glucoside inhibits high glucose-induced vascular inflammation. Inflammation. 2014. April 37(2):306-313. (*First author). (IF: 4.092) (*These authors contributed equally to this work)

13)  Wonhwa Lee*, Sae-Kwang Ku*, Byung-Woon Min, Sangkyu Lee, Jun-Goo Jee, Jeong Ah Kim, Jong-Sup Bae. Vascular barrier protective effects of pellitorine in LPS-induced inflammation in vitro and in vivo. Fitoterapia. 2014 January. 92:177-187. (*First author). (IF: 2.882) (*These authors contributed equally to this work)

14)  Wonhwa Lee*, Sae-Kwang Ku*, You-Mie Lee, Jong-Sup Bae. Anti-septic effects of glyceollins in HMGB1-induced inflammatory responses in vitro and in vivo. Food and Chemical Toxicology. 2014 Jan. 63:1-8. (*First author). (IF: 6.023) (*These authors contributed equally to this work)

[2013, Total : 8, First author : 7]

1)  Wonhwa Lee*, Hayoung Yoo*, Sae-Kwang Ku*, Jung Ah Kim and Jong-Sup Bae. 

Anticoagulant activities of piperlonguminine in vitro and in vivo. 

BMB reports. 2013 Oct. 46(10):484-489. (*First author). (IF: 4.667) (*These authors contributed equally to this work)

2)  Sae-Kwang Ku, Wonhwa Lee, Hayoung Yoo, Chang-Kyun Han, Jong-Sup Bae. 

Inhibitory effects of epi-sesamin on endothelial protein C receptor shedding in vitro and in vivo. 

Inflammation research. 2013. October 1. 62: 895-902. (*First author). (IF: 4.575) (*These authors contributed equally to this work)

3)  Wonhwa Lee*, Sae-Kwang Ku*, Jong-Sup Bae. 

Emodin-6-O-β-D-glucoside down-regulates endothelial protein C receptor shedding.

Archives of Pharmacal Research. 2013. September 30. 36:1160–1165. (*First author). (IF: 4.946) (*These authors contributed equally to this work)

4)  Wonhwa Lee*, Hayoung Yoo, Jung Ah Kim, Sangkyu Lee, Jun-GooJee, Min Young Lee, You-Mie Lee, Jong-Sup Bae. 

Barrier protective effects of piperlonguminine in LPS-induced inflammation in vitro and in vivo. 

Food and Chemical Toxicology. 2013. April 22. 58C:149-157. (*First author). (IF: 6.023) (*These authors contributed equally to this work)

5)  Eun-Ju Yang*, Sae-Kwang Ku*, Wonhwa Lee*, Sangkyu Lee, Taeho Lee, Kyung-Sik Song, Jong-Sup Bae. 

Barrier protective effects of rosmarinic acid on HMGB1-induced inflammatoryresponsesin vitro and in vivo. 

Journal of Cellular Physiology. 2013. May, 228(5):975-982. (*First author). (IF: 6.384) (*These authors contributed equally to this work)

6)  Wonhwa Lee*, Sae-Kwang Ku*, Jeong Ah Kim, Taeho Lee, Jong-Sup Bae. 

Inhibitory effects of epi-sesamin on HMGB1-induced vascular barrier disruptive responses in vitro and in vivo. 

Toxicology and Applied Pharmacology. 2013. March 15, 267(3):201-208. (*First author). (IF: 4.219) (*These authors contributed equally to this work)

7)  Wonhwa Lee*, Eun-Ju Yang*, Sae-Kwang Ku*, Kyung-Sik Song, Jong-Sup Bae. 

Anti-inflammatory effects of oleanolic acid on LPS-induced inflammation in vitro and in vivo. 

Inflammation. 2013. Febrary 1.36(1):94-102. (*First author). (IF: 4.092) (*These authors contributed equally to this work)

8)  Wonhwa Lee*, Sae-Kwang Ku*, Tae Hoon Kim, Jong-Sup Bae. 

Emodin-6-O-β-D-glucoside inhibits HMGB1-induced inflammatory responses in vitro and in vivo. 

Food and Chemical Toxicology. 2013. Febrary 1. 52:97-104. (*First author). (IF: 6.023) (*These authors contributed equally to this work)

[2012, Total : 7, First author : 5, Co-author : 2]

1)  Wonhwa Lee*, Sae-Kwang Ku*, and Jong-Sup Bae. 

Barrier protective effects of rutin in LPS-induced inflammation in vitro and in vivo. 

Food and Chemical Toxicology. 2012. Sep 1, 50 (9): 3025 – 3031. (*First author). (IF:6.023) (*These authors contributed equally to this work)

2)  Wonhwa Lee*, Eun-Ju Yang*, Sae-Kwang Ku*, Kyung-Sik Song, Jong-Sup Bae. 

Anticoagulant activities of oleanolic acid via inhibition of tissue factor expressions. 

BMB Reports. 2012. July 31, 45 (7): 390-395 (*First author). (IF:4.778) (*These authors contributed equally to this work)

3)  Wonhwa Lee*, Tae Hoon Kim*, Sae-Kwang Ku*, Kyoung-jin Min, Hyun-Shik Lee, Taeg Kyu Kwon, Jong-Sup Bae. 

Barrier protective effects of withaferin A in HMGB1-induced inflammatory responses in both cellular and animal models. 

Toxicology and Applied Pharmacology. 262 (2012) Jul, 45(7): 91–98. (*First author). (IF:4.219) (*These authors contributed equally to this work)

4)  Jong-Sup Bae, Wonhwa Lee, and Alireza R. Rezaie. 

Polyphosphate elicits proinflammatory responses that are counteracted by activated protein C in both cellular and animal models. 

Journal of Thrombosis and Haemostasis. 2012. Jun : 10 (6): 1145 - 1151. (IF:5.824)

5)  Wonhwa Lee*, Sae-Kwang Ku*, Jae WoanBae, Jong-Sup Bae. 

Inhibitory effects of lycopene on HMGB1-mediated pro-inflammatory responses in both cellular and animal models. 

Food and Chemical Toxicology. 2012 Jun, 50(6):1826- 1833. (*First author). (IF:6.023) (*These authors contributed equally to this work)

6)  Dong-Chan Kim, Sae-Kwang Ku, Wonhwa Lee and Jong-Sup Bae. 

Barrier protective activities of curcumin and its derivative. 

Inflammation Research. 2012 May;61(5):437-444. (IF:4.575)

7)  Eun-Ju Yang*, Wonhwa Lee*, Sae-Kwang Ku*, Kyung-Sik Song, Jong-Sup Bae. 

Anti-inflammatory activities of oleanolic acid on HMGB1 activated HUVECs. 

Food and Chemical Toxicology. 2012 May ; 50 (5) : 1288 - 1294. (*First author). (IF:6.023) (*These authors contributed equally to this work)

 [2011, Total : 1, Co-author : 1]

1)  Dong-Chan Kim, Wonhwa Lee and Jong-Sup Bae. 

Vascular anti-inflammatory effects of curcumin on HMGB1-mediated responses in vitro. 

Inflammation Research. 2011. December 1: 60 (12): 1161 – 1168. (IF:4.575)