Publications

Main-author publications from Kim lab are highlighted by green

at UNC

A Genetic Screen for Modifiers of Cohesin Clustering Identifies Regulators of Genome Folding

Kim W#, Park DS, Nguyen SC, Yang R, Joyce EF, Jain R#

under revision. #co-coresponding authors.

Transcription and Cohesin Direct Domain Boundary Spatial Positioning and Underpin Friedreich’s Ataxia

Karnay A, Linares R, Wang Q, Gardner Z, Liang J, Santini GT, Haridhasapavalan KK, Nguyen SC, Hugelier S, Shewale B, Kanemaki M, Napierala M, Wilson R, Dubois N, Poleshko A, Kim W, Shah PP, Lakadamyali M, Joyce EF, Jain R

under revision

Before UNC

MeCP2 interacts with the super elongation complex to regulate transcription

Sonn JY, Kim W, Iwanaszko M, Aoi Y, Li Y, Qi G, Parkitny L, Brissette JL, Weiner L, Botas J, Al-Ramahi I, Shilatifard A#, Zoghbi HY#

Sci. Adv. (2025) Nov 26;11(48):eadt5937. #co-coresponding authors.

High-throughput Oligopaint screen identifies druggable 3D genome regulators

Park DS, Nguyen SC, Isenhart R, Shah PP, Kim W, Barnett RJ, Chandra A, Luppino JM, Harke J, Wai M, Walsh PJ, Abdill RJ, Yang R, Lan Y, Yoon S, Yunker R, Kanemaki MT, Vahedi G, Phillips-Cremins JE, Jain R, Joyce EF

Nature (2023) Aug;620(7972):209-217.

BRD4 orchestrates genome folding to promote neural crest progenitor differentiation

Linares R*, Kim W*, Bolar NA*, Zhang H, Koch-Bojalad BA, Yoon S, Shah PP, Karnay A, Park DS, Luppino JM, Nguyen SC, Padmanabhan A, Smith CL, Poleshko A, Wang Q, Li L, Srivastava D, Vahedi G, Eom GH, Blobel GA, Joyce EF, Jain R

Nat. Genet. (2021) 53, 1480–1492. *co-first authors. 

Commented in Nat. Genet. BET proteins loop and compartmentalize the 3D genome, (2022) 54(4):370-371.

Disruption of MeCP2-TCF20 complex underlies different neurodevelopmental disorders

Zhou J, Hamdan H, Yalamanchili HK, Pang K, Pohodich AE, Lopez J, Shao Y, Oses-Prieto JA, Li L, Kim W, Durham MA, Bajikar SS, Palmer DJ, Ng P, Thompson ML, Bebin EM, Müller AJ, Küchler A, Kampmeier A, Haack TB, Burlingame AL, Liu Z, Rasband MN, Zoghbi HY

Proc. Natl. Acad. Sci. (2022) 119(4): e2119078119.

Dual targeting of brain region-specific kinases potentiates neurological rescue in Spinocerebellar ataxia type 1

Lee WS, Lavery L, Rousseaux MWC, Rutledge EB, Jang Y, Wan YW, Wu SR, Kim W, Al-Ramahi I, Rath S, Adamski CJ, Bondar VV, Tewari A, Soleimani S, Mota S, Yalamanchili HK, Orr HT, Liu Z, Botas J, Zoghbi HY

EMBO J. (2021) 40(7), e106106.

BRD4 Interacts with GATA4 to Govern Mitochondrial Homeostasis in Adult Cardiomyocytes

Padmanabhan A, Alexanian M, Linares-Saldana R, Gonzalez-Teran B, Andreoletti G, Huang Y, Connolly AJ, Kim W, Hsu A, Duan Q, Winchester S, Haldar SM, Jain R*, Srivastava D* 

Circulation (2020) 142(24), 2338-2355. *co-corresponding authors

Picking Winners and Losers: Cell Competition in Tissue Development and Homeostasis

Kim W, Jain R

Trends Genet. (2020) 36(7):490-498.

CORO7 functions as a scaffold protein for the core kinase complex assembly of the Hippo pathway

Park J, Jun K, Choi Y, Yoon E, Kim W, Jang YG, Chung J

J. Biol. Chem. (2020) 8;296:100040.

Von Hippel-Lindau tumor suppressor (VHL) stimulates TOR signaling by interacting with phosphoinositide 3-kinase (PI3K)

Hwang SH, Bang S, Kim W, Chung J

J. Biol. Chem. (2020) 295(8), 2336-2347.

Spatial activation of TORC1 is regulated by Hedgehog and E2F1 signaling in Drosophila eye

Kim W*, Jang YG*, Yang J, Chung J

Dev. Cell (2017) 42(4), 363-375. *co-first authors

Highlighted in Dev. Cell, Patchy Growth Control, (2017) 42(4):311-313.

Drosophila Low Temperature Viability Protein 1 (LTV1) Is Required for Ribosome Biogenesis and Cell Growth Downstream of Drosophila Myc (dMyc)

Kim W, Kim HD, Jung Y, Kim J#, Chung J#

J. Biol. Chem. (2015) 290(21), 13591-604. #co-corresponding authors

Host cell autophagy activated by antibiotics is required for their effective antimycobacterial drug action

Kim JJ, Lee HM, Shin DM, Kim W, Yuk JM, Jin HS, Lee SH, Cha GH, Kim JM, Lee ZW, Shin SJ, Yoo H, Park YK, Park JB, Chung J, Yoshimori T, Jo EK

Cell Host Microbe. (2012) 11(5), 457-68.

Drosophila Salt-inducible Kinase (SIK) Regulates Starvation Resistance through cAMP-response Element-binding Protein (CREB)-regulated Transcription Coactivator (CRTC)

Choi S, Kim W, Chung J

J. Biol. Chem. (2011) 286(4), 2658-64.

Loss of LRRK2/PARK8 induces degeneration of dopaminergic neurons in Drosophila

Lee SB*, Kim W*, Lee S*, Chung J

Biochem. Biophys. Res. Commun. (2007) 358(2), 534-539. *co-first authors