Provine High School-Millsaps College Partnership
funded by
funded by
The Provine High School - Millsaps College Partnership was established in June 2018 by Omega Hart (Provine) and Wolfgang Kramer (Millsaps).
Kelvin Gardner, a Provine High School rising Junior, spent the summer of 2018 in the Kramer lab at Millsaps and investigated the cleaving efficiency of bifunctional DNA-cleaving compounds based on N-substituted aromatic heterocycles.
In the Fall of 2018, Lakedra Gatlin, a Provine High School Junior, joined the lab and worked on the DNA-binding of the aforementioned compounds.
In the Spring of 2019, Cesar Escobar joined the team and worked with Kelvin on the DNA-binding of our compounds.
The summer of 2019 is seeing two Provine Students in the lab, Kelvin Gardner and Jania Hines. Both are working on the spectroscopic analysis of DNA interactions with bifunctional DNA-cleaving compounds synthesized in the lab. UV/Vis, fluorescence and CD spectroscopy are used to analyze the interactions and mathematical models are employed to determine apparent binding constants.
Poster Presentation: "Analysis of the Photoinduced DNA-Cleavage Activity of N-Methoxy Substituted Aromatic Heterocycles" (Press releases: 1, 2 )
Kelvin D. Gardner, Courtney Mullins, Lauren Hoth, Emily Stewart, Wolfgang Kramer*
Poster Presentation: "Analysis of the DNA-Interactions of N-Methoxy Substituted Aromatic Heterocycles: DNA-Binding and Cleaving"
Kelvin D. Gardner, Courtney B. Mullins, Lauren M. Hoth, Gurjit Kaur, Austin C. Baker, Emily H. Stewart, B. Woods Curry, Malika S. Shettar, Irene S. Corrao, Wolfgang H. Kramer*
Poster Presentation: "Analysis of the DNA-Interactions of N-Methoxy Substituted Aromatic Heterocycles: DNA-Binding and Cleaving"
Kelvin D. Gardner, Courtney B. Mullins, Lauren M. Hoth, Gurjit Kaur, Emily H. Stewart, B. Woods Curry, Malika S. Shettar, Irene S. Corrao, Wolfgang H. Kramer*
Poster Presentation: "Analysis of the DNA-Interactions of N-Methoxy Substituted Aromatic Heterocycles: DNA-Binding and Cleaving"
Cesar A. Escobar, Kelvin D. Gardner, Courtney B. Mullins, Lauren M. Hoth, Gurjit Kaur, Emily H. Stewart, B. Woods Curry, Malika S. Shettar, Irene S. Corrao, Wolfgang H. Kramer*
Oral Presentation: "Analysis of the DNA-Interactions of N-Methoxy Substituted Aromatic Heterocycles: DNA-Binding and Cleaving"
Kelvin D. Gardner, Courtney B. Mullins, Lauren M. Hoth, Gurjit Kaur, Emily H. Stewart, B. Woods Curry, Malika S. Shettar, Irene S. Corrao, Wolfgang H. Kramer*
Poster Presentation: "DNA-Binding Efficiency of Bifunctional Heteroaromatic Salts"
Jania E. Hines, Kelvin D. Gardner, Courtney B. Mullins, Melinda K. Solomon, Lauren M. Hoth, Wolfgang H. Kramer*
Poster Presentation: "Apparent Binding Constants for DNA Interactions of Bifunctional Heteroaromatic Salts"
Kelvin D. Gardner, Courtney B. Mullins, Melinda K. Solomon, Lauren M. Hoth, Wolfgang H. Kramer*