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Molecular mechanism of bacteriophage contraction structure of an S-layer–penetrating bacteriophage
Molecular mechanism of bacteriophage contraction structure of an S-layer–penetrating bacteriophage
Authors: Jason S Wilson, Louis-Charles Fortier, Robert P Fagan, Per A Bullough
Publication date: 26 March 2025
Key Findings: We determined the first entire phage structure of a C. difficile infecting bacteriophage (phiCD508). We find that phiCD508 has a number of critical adaptations such are compact needle and reduced contraction. These characteristics appear to be conserved amongst phages infecting S-layer producing bacteria.
Large scale capsid-mediated mobilisation of bacterial genomic DNA in the gut microbiome
Large scale capsid-mediated mobilisation of bacterial genomic DNA in the gut microbiome
Authors: Tatiana Borodovich, Jason S. Wilson, Pavol Bardy, Muireann Smith, Conor Hill , Ekaterina Khokhlova , Bianca Govi, Paul C.M. Fogg, Colin Hill & Andrey N. Shkoporov
Publication date: November 2024
Abstract: This research investigates the effectiveness of Google Sites as a platform for academic research collaboration and data sharing among universities.
Review: Gene transfer agents: structural and functional properties of domesticated viruses
Review: Gene transfer agents: structural and functional properties of domesticated viruses
Authors: Matthew W. Craske, Jason S. Wilson, and Paul C.M. Fogg
Publication date: December 2024
Highlights: GTAs are derived from ancient bacteriophages, but they have developed characteristic properties that absolve them of the typical viral lifestyle. Our understanding of GTA regulation has advanced rapidly in the past decade. Regulation is intricately controlled via quorum sensing, SOS response, stringent response, sigma factor 70, the pleiotropic regulator CtrA, two-component systems, phosphorelays, cyclic-di-GMP and GTA-specific activators/repressors.
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