Our lab focuses on quantitative and physical biology in bacterial model organisms. The long-term goal of the lab is to discover emergent properties and principles that describe the function of living systems. Our recent work includes work on protein overabundance, central dogma optimization, metabolic homeostasis, and measurements of in vivo replication fork velocity. We exploit a range of experimental and theoretical approaches from single-molecule imaging to high-throughput genetic and modeling approaches. The lab also works on developing novel tools for quantitative biology, including tools for cell segmentation using  machine learning algorithms. We are based in the departments of Physics, Bioengineering, and Microbiology at the University of Washington in Seattle.