You’ve read the word “needle,” and your shoulders just crept up toward your ears. Fair enough. Most people searching for a perineural injection want one answer first: Will it hurt?
Here’s the short version. Expect a quick pinch and a little sting, not a deep, scary jab. The longer version is below, minute by minute. At Learn Neural Therapy, we teach the clinicians who give these treatments, so we know what really happens in the room.
What is a Perineural Injection?
“Perineural” simply means “around the nerve.” During a perineural injection, a clinician places a small amount of fluid, dextrose (a simple sugar solution), just under the skin near an irritated nerve. The goal is to calm that nerve so it stops sending loud pain signals.
You may also see it called PIT injection therapy . It belongs to a bigger group of treatments known as neural injection therapy, which focus on how the nervous system affects pain and healing.
Your Session, Step by Step
Before the Needle: The Conversation
Your visit starts with talking. The provider asks where it hurts, when it started, and what makes it worse. Then they may press gently along your skin to find tender nerve spots. If a nerve is cranky, that pressing can feel sore for a second or two. It’s useful, because it shows where to treat.
During the Injection: The Pinch
The needle is very thin, and it only goes just under the skin. Most people describe a quick pinch, a mild sting, or a tiny burning feeling. Some feel tingling or warmth that fades fast.
You might notice small bumps, a bit like mosquito bites, where the fluid sits. They usually settle down soon. One session can include several spots, but each one takes only seconds.
Right After: The Check-In
Some people feel looser or lighter within minutes. Others feel no change yet. Both are normal. Mild soreness or a small bruise can show up, and it’s usually minor.
How Painful Is It, Really?
Pain is personal, so be wary of anyone who promises “you won’t feel a thing.” Still, many patients say it’s easier than they expected. Areas with thin skin or lots of nerve endings, like the face, hands, or feet, tend to feel sharper. A few easy ways to make it smoother:
Tell your provider if you’re nervous. They can slow down.
Breathe out slowly as the needle goes in.
Ask whether a cooling spray or numbing option fits your situation.
Eat something beforehand so you don’t feel lightheaded.
What Happens After Your First Visit?
Don’t expect a one-and-done miracle. Relief can be short at first and then last longer with each visit. Many people need a series of sessions spaced days or weeks apart. Your provider will adjust the plan based on how your body responds.
Why Your Provider Matters
Nerves run in tiny, specific paths. A treatment like this works best when the person holding the needle knows that map by heart. That’s why choosing trained neural therapy specialists matters more than choosing the fanciest clinic.
Learn Neural Therapy offers hands-on and virtual classes for physicians, NPs, PAs, chiropractors, and acupuncturists. Our programs cover everything from beginner neural therapy to advanced perineural injection techniques for the upper body, lower body, and more. Better-trained providers mean calmer, more confident sessions for you.
Ready to Find Out for Yourself?
A perineural injection is quicker and gentler than most people imagine, especially with a skilled hand behind the needle. Ready to find a trained provider, or to become one? Visit Learn Neural Therapy, use the Find a Provider page, or get in touch to ask about classes today.
Does a perineural injection hurt?
Most people feel a brief pinch and sting. Discomfort usually fades quickly.
How many sessions will I need?
It depends on your condition and how long you’ve had it. Expect a series, not a single visit.
Who can perform Perineural Injection Therapy?
Licensed healthcare providers with proper training in nerve anatomy and injection technique.
Is it the same as a steroid shot?
No. These injections typically use a different approach, so ask your provider what’s in the syringe.