Metformin, marketed under the trade name Glucophage among others, is the first-line medication for the treatment of type 2 diabetes, particularly in overweight people. It is reported that Metformin (Glucophage) may cause weight loss as a side effect due to loss of appetite in patients. However, this is not the intended use and it is not considered as a weight loss supplement.
Yes, Metformin (Glucophage) has proven weight loss results for the patients tested over a long time. A study showed weight loss after taking it for a couple of years. However, it won't have any immediate results and shouldn't be considered as a shortcut to quickly lose weight.
Yes. The overweight people without diabetes can also use Metformin (Glucophage). However, it's a prescription drug and you can't just buy it from stores. Your doctor may suggest traditional alternatives as weight loss is not the intended use for these tablets. FDA didn't approve these pills for weight loss and they shouldn't be considered as weight loss supplements.
In May 2020, the Food and Drug Administration (FDA) recommended that some makers of metformin extended release remove some of their tablets from the U.S. market. This is because an unacceptable level of a probable carcinogen (cancer-causing agent) was found in some extended-release metformin tablets. If you currently take this drug, call your healthcare provider. They will advise whether you should continue to take your medication or if you need a new prescription.
The following are the popular videos of Metformin (Glucophage) on YouTube:
Metformin treatment for diabetes results in a lower resultant body weight compared to other options. Some studies reported weight loss – in some cases up to 2.9kg after using these pills.
Yes. Metformin reduces appetite and results in weight loss. However, it shouldn't be considered as a replacement to traditional weight loss supplements.
Some studies indicate that the regular use of metformin results in the weight loss including the reduction in belly fat. This is considered as a result of suppression of appetite.
Insulin makes people overweight by acting on the brain to cause hunger, making the liver manufacture fat and fill fat cells in the stomach. Metformin (Glucophage) helps people with diabetes to lose weight by lowering their appetites.
According to one long-term study , the weight loss from metformin tends to occur gradually over one to two years. The amount of weight lost also varies from person to person. In the study, the average amount of weight lost after two or more years was 4-7 pounds (1.5-3 kgs).
Metformin leads to significant reduction in testosterone levels, sex drive and induction of low testosterone-induced erectile dysfunction.
According to the University of Michigan, you should avoid eating high-fiber foods after taking metformin. This is because fiber can bind to drugs and lower their concentration. Metformin levels decrease when taken with large amounts of fiber (greater than 30 milligrams per day).
It is also possible that metformin may cause hair loss indirectly. Taking metformin long-term may increase the risk of vitamin B-12 deficiency, which can sometimes cause hair loss.
The function of diabetes drug Glucophage is to reduce the release levels of sugar from your liver. This stops blood glucose levels from rising too high, and means that the body does not have to produce as much insulin.
Metformin (Glucophage) side effects by likelihood and severity:
Common cold
Abdominal bloating
Diarrhea
Gas
Headache
Inadequate Vitamin B12
Nausea
Taste impairment
According to research, metformin can help some people lose weight. However, it's not clear why metformin may cause weight loss. One theory is that it may prompt you to eat less by reducing your appetite. It may also change the way your body uses and stores fat.
Metformin (Glucophage) does not cause kidney damage. The kidneys process and clear the drug out of your system via urine. If your kidneys are not functioning properly, metformin can build up in your system and cause a condition called lactic acidosis. Lactic acidosis is when there is a dangerous amount of lactic acid in the body.