Programme*
*All times are GMT+1
26th July
Opening Session - Chair: Mª Lourdes Pereira, PhD
13.45 - 14.15 h
Opening Ceremony
Mª de Lourdes Pereira - Assistant Professor - University of Aveiro
Paulo Jorge Ferreira - Rector of the University of Aveiro
Henrique Cyrne de Carvalho - Director of ICBAS-UP
Mariana P. Monteiro - Director of UMIB - ICBAS-UP
Odete Cruz e Silva - Director of the Department of Medical Sciences, UA
Sónia Ventura, on behalf of Armando Silvestre - Director of the Chemistry Department, UA
Manuel Santos - Director of IBIMED, UA
João Rocha - Director of CICECO, UA
Session I - Antioxidants Therapy and Fertility - Chair: Marco G. Alves, PhD
14.15 - 14.50 h
Ashok Agarwal, MD, PhD
Facts about the role of antioxidants in male infertility: an evidence based dialogue with researchers and clinical audience
14.50 - 15.25 h
Lúcia von Mengden Meirelles, MSc
Applications of anti-oxidants in vitro for improving oocyte maturation outcomes
15.25 - 15.40 h
Selected talk 1
Astaxanthin relieves busulfan-induced apoptosis in cultured human spermatogonial stem cells by activating Nrf-2/HO-1 pathway
Azita Afzali, Iran
15.40 - 15.55 h
Selected talk 2
Impact of hyperoside supplementation on the quality of human sperm
Mafalda Moreira, Portugal
15.55 - 16.10 h
Poster Session 1
Relationship between vitamin D and female reproductive health: a systematic review
Giovanna Safraid, BrazilDifferential expression of seminal Nrf-2 and SOD1 in relation to oxidation-reduction potential (ORP) in oligozoospermic men: A pilot study
Manesh Kumar Panner Selvam, USAExtracellular ATP levels alter the effects of congenital hypothyroidism in calcium influx and in oxidative stress parameters in immature rat testis
Vitoria Hayduck Cenci, BrazilThe all-trans retinoic acid presents antioxidant properties within human ovary and reduces progesterone production by human granulosa cells
Bruno M. Fonseca, PortugalMitochondrial dynamics markers and related signaling molecules are important regulators of spermatozoa number and functionality
Isidora M. Starovlah, Serbia
Session II - Technologies and biomimetic systems in reproduction - Chair: Mário Barbosa, PhD
16.15 - 16.50 h
Nuno Costa-Borges, PhD
Maternal spindle transfer as a novel technique to treat infertility associated to poor oocyte quality
16.50 - 17.25 h
Paolo Netti, PhD
Enabling technologies for improving precision in assisted procreation
17.25 - 17.40 h
Selected talk 3
Positive Rheotaxis Extended Drop (PRED) technique improves blastocyst rate in patients with at least one failed ICSI cycle with low blastocyst rate - a pilot study
Sayali Kandari, India
17.40 - 17.55 h
Selected talk 4
Is FMR1 allelic score a useful biomarker for preferential X-chromosome inactivation in infertile females?
Bárbara Rodrigues, Portugal
17.55 - 18.10 h
Poster Session 2
Clusterin as a potential marker to evaluate sperm quality
Jéssica Moreira, PortugalArylsulfatase A (ARSA): a potential quality biomarker for sperm cryopreservation
Pedro O. Corda, PortugalActivation of sirtuin pathway enhances human sperm capacitation status
David Martín-Hidalgo, SpainRobertsonian translocation in infertility: a case report
Catarina Pinto, PortugalMetal oxide nanoparticles affect spermatogonia: preliminary in vitro studies
Mariana Vassal, Portugal
Round Table (PT) - Mesa Redonda - Novos desafios no tratamento da fertilidade - Aberto Sociedade - Youtube, SLIDO - Moderadora: Patrícia Matos, jornalista
18.15 - 19.30 h
Novos desafios no tratamento da fertilidade
Cláudia Vieira, Associação Portuguesa de Fertilidade (APF)
Vladimiro Silva, PharmD, MSc - Ferticentro/Procriar
Vera Lúcia Raposo, Jurista
Luís Ferraz, MD, PhD - C.H.V.N.G.
Mariana P. Monteiro, MD, PhD - Endocrinologia Reprodutiva
27th July
Session III - 100 years of Insulin discovery - impact on fertility (promoted by SPD) - Chair: Paula Macedo, PhD
9.00 - 9.35 h
Pedro F. Oliveira, PhD
Male fertility and insulin
9.35 - 10.10 h
Swathi Arur, PhD
Insulin signalling and oogenesis in C. elegans
10.10 - 10.25 h
Selected talk 5
Human spermatozoa secrete insulin in a glucose-dependent manner
David F. Carrageta, Portugal
10.25 - 10.40 h
Selected talk 6
Mitochondrial Dynamics Markers are important regulators of Leydig cells and spermatozoa functionality
Silvana Andric, Serbia
10.40 - 10.55 h
Poster Session 3
Expression Profile of Mitochondrial Uncoupling Proteins (UCPs) in Human Sertoli cells
Bruno Monteiro, PortugalModulation of MCT4 trafficking by glucose levels – do Sertoli cells behave as Cancer cells?
Rafaela A. Oliveira, PortugalIdentification of the mRNA expression of Mitochondrial Uncoupling Proteins (UCPs) in Human Spermatozoa
Laís Freire-Brito, PortugalDeficiency of the insulin-like growth factors signaling disturbs the androgen phenotype but increases aromatase activity in male mouse Leydig cells
Sava Radovic Pletikosic, Serbia
Session IV - Aging and fertility - Chair: Margarida Fardilha, PhD
11.00 - 11.35 h
Artur Mayerhofer, MD, PhD
Peritubular cells – a window into the (aging) human testis
11.35 - 12.10 h
Emídio Vale-Fernandes, MD, PhD
The decline of ovarian function from the reproduction perspective
12.10 - 12.25 h
Selected talk 7
Cellular senescence and oxidative stress: relevance in age-related fertility loss
Adriana Guerreiro, Portugal
12.25 - 12.40 h
Selected talk 8
PCNA positive cells in the transitional distal segment of seminiferous tubule, tubuli recti and rete testis in Syrian hamster testes
Vicente Seco Rovira, Spain
12.40 - 13.00 h
Poster Session 4
COVID-19 and Fertility
Samiya Khan, IndiaDysregulation of FSH and testosterone in mouse Sertoli cells: impact in glycerol permeability
Bruno Lopes, PortugalTesticular "Inherited metabolic memory" of high-fat diet causes sperm defects up to grandsons
Luís Crisóstomo, PortugalTranscriptional profiles of mitochondrial dynamics markers in human spermatozoa are associated with different types of spermiograms
Tamara Tomanic, SerbiaTransgenerational reproductive effects (F2) in male offspring mediated by F0 generation exposure to Benzo(A)pyrene from juvenile period to peripuberty in rats
Julia Stein, Brazil
Session V - Lifestyle, Environment and reproduction - Chair: Mª. Lourdes Pereira, PhD
14.00 - 14.35 h
Prof. Ariane Zamoner
Environment and male fertility
14.35 - 15.10 h
Susana Loureiro, PhD
Integrating environmental and human monitoring: a case study of parental and pre-natal exposure to harmful substances in Aveiro region
15.10 - 15.25 h
Selected talk 9
Sperm quality assessment in Ficopomatus enigmaticus (Fauvel, 1923): effects of selected organic and inorganic chemicals under salinity variations
Alessia Cuccaro, Italy
15.25 - 15.40 h
Selected talk 10
Benzo(a)pyrene exposure in peripubertal males: reproductive consequences in F1 and F2 generation female rats.
Bárbara Jorge, Brazil
15.40 - 15.55 h
Poster Session 5
Losartan does not prevent acute tubular damage in irradiated testes
Maria Angélica Spadella, BrazilThe phytocannabinoid Δ9-tetrahydrocannabinol disturbs extravillous trophoblasts angiogenesis
João Maia, PortugalCannabidiol impact in human trophoblast cells migration/invasion
Patrícia Alves, PortugalTechnical-grade chlordane negatively impacts rat Sertoli cells physiology
Bruno P. Moreira, PortugalInfluence of in utero exposure to ondansetron: teratogenic effects and late repercussions on reproductive and behavioral parameters in male rats
Ana Reis, BrazilNegative effects of the herbicide Round up® Ultra Plus in human spermatozoa are not mediated by its active ingredient glyphosate
Mercedes Torres Badia, Spain
Session VI - Contraception - Chair: Pedro F. Oliveira, PhD
16.00 - 16.35 h
Prof. Erick Silva
Moving towards the “male pill”: protein-protein interactions in spermatozoa as targets for male contraception.
16.35 - 17.10 h
Margarida Fardilha, PhD
Targeting sperm motility as a male contraceptive strategy: disruption of protein phosphatase 1 complexes with bioportides
17.10 - 17.25 h
Selected talk 11
Concanavalin A binding proteins of human seminal plasma: Understanding their role in male fertility/infertility
Savita Yadav, India
17.25 - 17.40 h
Selected talk 12
Factors influencing the use of IMPLANON as contraceptive.
Manurachna Pathmanathan, Malaysia
17.40 - 18.00 h
Poster Session 6
Sperm aquaglyceroporins as an important marker for human sperm motility
João Ribeiro, PortugalCFTR and Estrogen modulates aquaglyceroporins in mouse Sertoli cells: implications to male fertility
Raquel Bernardino, PortugalIdentification of the seminal plasma protein SVS2 sequence required to interact with its binding partner EPPIN in mouse spermatozoa: an in vitro study
Noemia Mariani, BrazilEPPIN antibodies mapping N-terminal and C-terminal sequences impair mouse sperm motility and fertilizing ability
Alan Silva, Brazil
Special Session - Chair: Vladimiro Silva, PharmD, MSc, Center for Fertility Studies, Coimbra, Portugal
18.00 - 18.30 h
Mauro Gacci, MD, PhD
Semen impairment after COVID-19: potential impact on male fertility
Closing Session - Chairs: Margarida Fardilha, PhD and Marco G. Alves, PhD
18.30 - 19.00 h
Award Ceremony
Erwin Goldberg Tribute