Infection Immunology Lab (2i-lab)

Infection Immunology Lab (2i-lab) is located at the Department of Biological Sciences, Indian Institute of Science Education and Research (IISER) Mohali, Punjab. In January 2022, the 2i-lab moved to IISER Mohali from NIT Rourkela Odisha. The lab's primary focus is on host-pathogen interaction and looking forward to understanding the bacterial evolution, the impact of infection on a host, and their response. We majorly use C. elegans, and also the murine model as a model system.

Current Members

Vidya Devi Negi (Principal Investigator)

I did my Master in Zoology from Himachal Pradesh University, Shimla and then moved to IISc Bangalore to pursue PhD in the field of Microbiology. I had a chance to work on a very challenging field of infection biology and my mentor had a significant impact on shaping my career and the personality that I have today. My lab mostly focus on the impact of Salmonella infection on host development and regulation of Salmonella pathogenesis and microbial evolution.

Graduate students

Ayushi Raturi (2022)

Ayushi did her Bachelor's and Master's in Zoology from DU, and is currently working on decoding the molecular mechanism of CRISPR-Cas system mediated regulation of Salmonella Typhi pathogenesis. Ayushi wishes to learn more about the moonlighting functions of the CRISPR-Cas system in S.Typhi.

Chamjai Daimai (2022)

Chamjai did her masters in Zoology from Dolphin P.G Institute of Biomedical and Natural Sciences, Dehradun. She is interested in understanding and exploring the Salmonella effector proteins mediating the developmental defects in C. elegans and identifying various host immuno-stimulatory compounds that are differentially regulated in response to Salmonella infection.

Ayushi M Singh ( 2023)

Ayushi did her masters in Biochemistry from Sardar Patel University Dept Of Biosciences, Gujarat.

Ayushi is interested in looking into mechanism of host-pathogen interaction using C. elegans, cell lines and Salmonella model desifering the role of iron in Salmonella pathogenesis and biofilm formation

Nikita Varma (2023)

Nikita did her masters in molecular biology and biochemistry from Guru Nanak Dev University, Amritsar.

Nikita is interested in understanding the molecular mechanisms of non-SPI genes in Salmonella, which might indirectly modulates pathogenesis and promotes survival within the host, using cell line and mice models

Subodh D Telgote (2025)

Subodh did his Bachelor’s in Microbiology from DSM college, Parbhani, Maharashtra. Joined IISER Mohali as an Integrated PhD student in August’23. He is currently investigating the role of Salmonella Typhi in Gallbladder cancer and impact of S. Typhi Infection on Immune Checkpoint molecules.