Current areas of study in our Lab
Current areas of study in our Lab
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Our laboratory examines signaling events that lead to migration of T cell acute lymphoblastic leukemic cells. C.I. Cardona et. al, IJMS, 2024
This is a small example of data generated in our studies
This is a small example of data generated in our studies
CCR7 stimiulation with either CCL19 or CCL21 leads to translocation of arrestin-3 from the cell membrane, while promoting traffing of CCL19 to a peri-nuclear compartment.
ERK5 may play a role in development of B-Cells.
ERK5 may play a role in development of B-Cells.
(Left) Image of an Lck-Cre Spleen, (Right) Image of an Erk5-Lck Cre Spleen. The ERK5-Lck Cre Spleen has multiple small B-cell zones when compared to the Lck-Cre mouse.
Our team has identified an antagonist to block migration of T-ALL into the CNS.
Our team has identified an antagonist to block migration of T-ALL into the CNS.
Our team has recently determined novel mechanisms involving CCR7 in regulating the development of the TCR repertoire
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