Our laboratory examines signaling events that lead to migration of T cell acute lymphoblastic leukemic cells. C.I. Cardona et. al, IJMS, 2024
G Protein Coupled Receptor Kinase 3 Regulates CCR7 Signaling, Trafficking, and T Cell Responses to CCL19 and CCL21
CCR7 stimiulation with either CCL19 or CCL21 leads to translocation of arrestin-3 from the cell membrane, while promoting traffing of CCL19 to a peri-nuclear compartment.
Charlotte Vines , Jaisel Cervantes , Colin Bill
The Journal of Immunology, Volume 212, Issue 1_Supplement, May 2024, Page 0510_5904, https://doi.org/10.4049/jimmunol.212.supp.0510.5904
https://www.mdpi.com/1422-0067/26/19/9744
Our team has recently determined novel mechanisms involving CCR7 in regulating the development of the TCR repertoire
Lab protocols