Singh M, Singh C, Nair AV, Ahmad I, Sharma A, Bhasin M, Jain V, Singh R, Thakur KG. Structural and functional characterization of VapBC52 toxin–antitoxin system from Mycobacterium tuberculosis. Nucleic Acids Res. 2026, 54: gkag611. (Abstract)
Sharma S, Jain V. Structural and functional relevance of DUF4352 domain in antiviral immunity and physiology of mycobacteria. Nucleic Acids Res. 2025, 53: gkaf1253. (Abstract)
Mulye M, Jain V. Molecular insights into the structure, function, and stability of the DNA polymerase processivity factor from Mycobacterium tuberculosis. J. Mol. Biol. 2025, 437: 169416. (Abstract)
Pillai SS, Jain V. Elucidating the role of mycobacteriophage D29-encoded Gp36 in DNA binding and phage gene expression regulation. Nucleic Acids Res. 2025, 53: gkaf662. (Abstract)
Jain S, Patil AG, Patil S, Mukherjee R, Jain V, Mahalakshmi R. Mycobacterium tuberculosis TtfA is a highly stable membrane-anchored DNA binding protein. J. Membrane. Biol. 2025, 258: 403-413. (Abstract)
Raman SK, Roy T, Verma K, Yadav C, Verma S, Deivreddy VSR, Sofi HS, Bharti R, Sharma R, Bansode H, Kumar A, Sharma RK, Singh J, Mugale MN, Bajpai U, Jain V, Singh AK, Misra A. Dry Powder Inhalation of Lytic Mycobacteriophages for Adjunct Therapy in a Mouse Model of Infection with Mycobacterium tuberculosis. Tuberculosis 2025, 152: 102631. (Abstract)
Gangakhedkar R, Jain V. Elucidating the molecular properties and anti-mycobacterial activity of cysteine peptidase domain of D29 mycobacteriophage endolysin. J. Virol. 2024, 98(10): e01328-24. (Abstract)
Gangakhedkar R, Jain V. Construing the function of N-terminal domain of D29 mycobacteriophage LysA endolysin in phage lytic efficiency and proliferation. Mol. Microbiol. 2024, 122(2): 243-254. (Abstract)
Raman SK, Siva Reddy DV, Jain V, Bajpai U, Misra A, Singh AK. Mycobacteriophages: therapeutic approach for mycobacterial infections. Drug Discov. Today. 2024, 29(7): 104049. (Abstract)
Nair G, Jain V. An intramolecular crosstalk in D29 mycobacteriophage endolysin governs the lytic cycle and phage-host population dynamics. Sci. Adv. 2024, 10: eadh9812. (Abstract)
Wani SR, Jain V. Deciphering the molecular mechanism and regulation of formaldehyde detoxification in Mycobacterium smegmatis. Appl. Environ. Microbiol. 2024, 90: e02039-23. (Abstract)
Singh AK, Gangakhedkar R, Thakur HS, Raman SK, Patil SA, Jain V. Mycobacteriophage D29 Lysin B exhibits promising antimycobacterial activity against drug-resistant Mycobacterium tuberculosis. Microbiol. Spectr. 2023, 11: e0459722. (Abstract)
Abdelrahman F, Gangakhedkar R, Nair G, El-Didamony G, Askora A, Jain V, El-Shibiny A. Pseudomonas phage ZCPS1 endolysin as a potential therapeutic agent. Viruses. 2023, 15: 520. (Abstract)
Wani SR, Dubey AA, Jain V. Ms6244 is a novel Mycobacterium smegmatis TetR family transcriptional repressor that regulates cell growth and morphophysiology. FEBS Lett. 2023, 597: 1428-1440. (Abstract)
Mulye M, Singh MI, Jain V. From Processivity to Genome Maintenance: The Many Roles of Sliding Clamps. Genes 2022, 13: 2058. (Abstract)
Seniya SP, Jain V. Decoding phage resistance by mpr and its role in survivability of Mycobacterium smegmatis. Nucleic Acids Res. 2022, 50: 6938-6952. (Abstract)
George A, Ravi R, Tiwari PB, Srivastava SR, Jain V, Mahalakshmi R. Engineering a Hyperstable Yersinia pestis Outer Membrane Protein Ail Using Thermodynamic Design. J. Am. Chem. Soc. 2022, 144: 1545-1555 (Abstract)
James S, Jain V. A positive selection Escherichia coli recombinant protein expression vector for one-step cloning. Front. Bioeng. Biotechnol. 2022, 9: 776828. (Abstract)
Wani SR, Jain V. Molecular dissection of a dedicated formaldehyde dehydrogenase from Mycobacterium smegmatis. Protein Sci. 2022, 31: 628-638. (Abstract)
Patil V, Jain V. Understanding metabolic remodelling in Mycobacterium smegmatis to overcome energy exigency and reductive stress under energy-compromised state. Front. Microbiol. 2021, 12: 722229. (Abstract)
Bavda VR, Yadav A, Jain V. Decoding the molecular properties of mycobacteriophage D29 Holin provides insights into Holin engineering. J. Virol. 2021, 95: e02173-20. (Abstract)
Nair G, Jain V. Separation of Mycobacterium smegmatis from a mixed culture using the cell wall binding domain of D29 mycobacteriophage endolysin. Front. Microbiol. 2020, 11: 1119. (Abstract)
Bavda VR, Jain V. Deciphering the role of holin in mycobacteriophage D29 physiology. Front. Microbiol. 2020, 11: 883. (Abstract)
Seniya SP, Yadav P, Jain V. Construction of E. coli—Mycobacterium shuttle vectors with a variety of expression systems and polypeptide tags for gene expression in mycobacteria. PLoS One. 2020, 15(3): e0230282. (Abstract)
Patil V, Jain V. Insights into the physiology and metabolism of a mycobacterial cell in an energy-compromised state. J. Bacteriol. 2019, 201: e00210-19. (Abstract)
Dubey AA, Jain V. Mycofactocin is essential for the establishment of methylotrophy in Mycobacterium smegmatis. Biochem. Biophys. Res. Commun. 2019, 516: 1073-1077. (Abstract)
Joshi H, Nair G, Gangakhedkar R, Jain V. Understanding the role of lysozyme-like domain of the D29 mycobacteriophage-encoded endolysin in the host cell lysis and phage propagation. Microbiology 2019, 165: 1013-1023. (Abstract)
Dubey AA, Jain V. MnoSR is a bona fide two-component system involved in methylotrophic metabolism in Mycobacterium smegmatis. Appl. Environ. Microbiol. 2019, 85: e00535-19. (Abstract)
Dubey AA, Wani SR, Jain V. Methylotrophy in mycobacteria: Dissection of the methanol metabolism pathway in Mycobacterium smegmatis. J. Bacteriol. 2018, 200: e00288-18. (Abstract)
Joshi H, Seniya SP, Suryanarayanan V, Patidar ND, Singh SK, Jain V. Dissecting the Structure-function Relationship in Lysozyme Domain of Mycobacteriophage D29-encoded Peptidoglycan Hydrolase. FEBS Lett. 2017, 591: 3276-3287. (Abstract)
Singh MI, Jain V. Identification and characterization of an inside-out intermediate in the folding pathway of bacteriophage sliding clamp. Biophys. J. 2017, 113: 1738-1749. (Abstract)
Mahalakshmi R, Maurya SR, Burdak B, Surti P, Patel MS, Jain V. Structural plasticity of T4 transcription co-activator gp33 revealed by a protease-resistant unfolded state. Biochem. Biophys. Res. Commun. 2017, 492: 61-66. (Abstract)
Joshi H, Jain V. Novel method to rapidly and efficiently lyse Escherichia coli for the isolation of recombinant protein. Anal. Biochem. 2017, 528: 1-6. (Abstract)
Kamilla S, Jain V. Robust high throughput real-time monitoring assay for the specific screening of bacterial cell envelope inhibitors. Proc. Indian Natn. Sci. Acad. 2017, 83: 211-215. (Abstract)
Singh MI, Ganesh B, Jain V. On the domains of T4 phage sliding clamp gp45: an intermolecular crosstalk governs structural stability and biological activity. Biochim. Biophys. Acta 2017, 1861: 3300-3310. (Abstract)
Dubey AA, Singh MI, Jain V. Rapid and robust PCR-based all-recombinant cloning methodology. PLoS One 2016, 11(3): e0152106. (Abstract)
Singh MI, Jain V. Molecular dissection of the homotrimeric sliding clamp of T4 phage: Two domains of a subunit display asymmetric characteristics. Biochemistry 2016, 55(3): 588-596. (Abstract)
Lella M, Kamilla S, Jain V, Mahalakshmi R. Molecular mechanism of holin transmembrane domain I in pore formation and bacterial cell death. ACS Chem. Biol. 2016, 11: 910-920. (Abstract)
Kamilla S, Jain V. Mycobacteriophage D29 holin C-terminal region functionally assists in holin aggregation and bacterial cell death. FEBS J. 2016, 283(1): 173-190. (Abstract)
Pohane AA, Jain V. Insights into the regulation of bacteriophage endolysin: Multiple means to the same end. Microbiology 2015, 161: 2269-2276. (Abstract)
Syal K, Joshi H, Chatterji D, Jain V. Novel pppGpp binding site at the C-terminal region of Rel enzyme from Mycobacterium smegmatis. FEBS J. 2015, 282(19): 3773-3785. (Abstract)
Pohane AA, Patidar ND, Jain V. Modulation of domain-domain interaction and protein’s function by a charged linker: A case study of mycobacteriophage D29 endolysin. FEBS Lett. 2015, 589(6): 695-701. (Abstract)
Sharma A, Pohane AA, Bansal S, Bajaj A, Jain V, Srivastava A. Cell Penetrating Synthetic Antimicrobial Peptides (SAMPs) Exhibiting Potent and Selective Killing of Mycobacterium by Targeting its DNA. Chem. Eur. J. 2015, 21(9): 3540-3545. (Abstract)
Ekal L, Ganesh B, Joshi H, Lama L, Jain V. Evidence of a conserved intrinsically disordered region in the C-terminus of the stringent response protein Rel from mycobacteria. FEBS Lett. 2014, 588: 1839-1849. (Abstract)
Pohane AA, Joshi H, Jain V. Molecular dissection of phage endolysin: An interdomain interaction confers host specificity in Lysin A of Mycobacterium phage D29. J. Biol. Chem. 2014, 289: 12085-12095. (Abstract)
Singh MI, Jain V. Tagging the Expressed Protein with 6 Histidines: Rapid Cloning of an Amplicon with Three Options. PLoS ONE 2013, 8(5): e63922. (Abstract)
Twist K, Campbell EA, Deighan P, Nechaev S, Jain V, Geiduschek EP, Hochschild A, Darst SA. Crystal structure of the bacteriophage T4 late-transcription co-activator gp33 with the β-subunit flap domain of E. coli RNA polymerase. Proc. Natl. Acad. Sci. USA 2011, 108(50): 19961-19966. (Abstract)
Jain V, Saleem-Batcha R, Chatterji D. Synthesis and hydrolysis of pppGpp in mycobacteria: a ligand mediated conformational switch in Rel. Biophys. Chem. 2007, 127(1-2): 41-50. (Abstract)
Jain V, Saleem-Batcha R, China A, Chatterji D. Molecular dissection of the mycobacterial stringent response protein Rel. Protein Sci. 2006, 15(6): 1449-1464. (Abstract)
Jain V, Kumar M, Chatterji D. ppGpp: Stringent response and survival. J. Microbiol. 2006 44(1): 1-10. (Abstract)
Jain V, Sujatha S, Ojha AK, Chatterji D. Identification and characterization of rel promoter element of Mycobacterium tuberculosis. Gene 2005, 351: 149-157. (Abstract)
Sivakumar P, Sharmila P, Jain V, Saradhi PP. Sugars have potential to curtail oxygenase activity of Rubisco. Biochem. Biophys. Res. Commun. 2002, 298: 247-250. (Abstract)