In our lab, we research how the nervous system works and how it responds and repairs itself due to the damage caused by injury or disease.
Our two main goals are to:
Discover strategies for enhancing neuronal regrowth and staling neuronal loss after injury.
Understand the nervous system response and recovery during damage caused by disease.
A unique feature of our lab is that we are focusing on integrating various omics techniques with basic neurobiology and systems analyses to develop a more systematic understanding of nerve injury and neurodegenerative conditions. Our long term research interest involves identification of the molecular mechanism responsible for neural repair and neuronal degeneration.
For more information, please click on the tabs above or contact us.
In vivo: Mice, & Rat
In vitro: Dorsal root ganglion neurons, cortical neurons and various cell lines
CNS and PNS nerve injury systems
Gene expression analyses by RNA sequencing
Proteomics by LC-MS/MS
Targeted metabolomics
In vivo drug delivery through osmotic pumps
Standard molecular biology and tissue culture techniques
Co-expression network analyses
Regulatory factor enrichment analyses
Protein-protein interaction network analyses
In silico small molecule screening
Various bioinformatics and bio-pipelines