2024
Makin, R. D., Apicella, I., Dholkawala, R., Fukuda, S., Hirahara, S., Hirano, Y., Kim, Y., Nagasaka, A., Nagasaka, Y., Narendran, S., Pereira, F., Varshney, A., Wang, S. B., Ambati, J., & Gelfand, B. D. (2024). Inflammasome activation aggravates choroidal neovascularization. Angiogenesis, 27(4), 919–929.PubMed
2023
Gupta, N., Kumar, A., Vaddavalli, P. K., Mahapatra, N. R., Varshney, A.*, & Ghosh, P.* (2023). Efficient reduction of the scrolling of Descemet membrane endothelial keratoplasty grafts by engineering the medium. Acta biomaterialia, 171, 239–248.PubMed *Corresponding Author
Rathore, S., Verma, A., Ratna, R., Marwa, N., Ghiya, Y., Honavar, S. G., Tiwari, A., Das, S., & Varshney, A. (2023). Retinoblastoma: A review of the molecular basis of tumor development and its clinical correlation in shaping future targeted treatment strategies. Indian journal of ophthalmology, 71(7), 2662–2676.PubMed
Gupta, N., Bhogal, M., Vaddavalli, P. K., Boldini, A., Semeraro, F., Varshney, A., & Romano, V. (2023). A goat eye, wet lab model for training in Descemet membrane endothelial keratoplasty. Indian journal of ophthalmology, 71(5), 2230–2233.PubMed
Das, S., & Varshney, A. (2023). Commentary: Can machine be taught to detect retinoblastoma?. Indian journal of ophthalmology, 71(2), 432–433.PubMed
Gupta, N., Varshney, A.*, Ramappa, M., Basu, S., Romano, V., Acharya, M., Gaur, A., Kapur, N., Singh, A., Shah, G., Chaudhary, I., Patel, N., Tiwari, A., Kate, A., Sangwan, V., & Mathur, U. (2022). Role of AS-OCT in Managing Corneal Disorders. Diagnostics (Basel, Switzerland), 12(4), 918.PubMed *Corresponding author
2022
Ambati, B. K., Varshney, A., Lundstrom, K., Palú, G., Uhal, B. D., Uversky, V. N., & Brufsky, A. M. (2022). MSH3 Homology and Potential Recombination Link to SARS-CoV-2 Furin Cleavage Site. Frontiers in virology (Lausanne, Switzerland), 2, 834808.PubMed
2021
Wang, S. B., Narendran, S., Hirahara, S., Varshney, A., Pereira, F., Apicella, I., Ambati, M., Ambati, V. L., Yerramothu, P., Ambati, K., Nagasaka, Y., Argyle, D., Huang, P., Baker, K. L., Marion, K. M., Gupta, K., Liu, B., Hinton, D. R., Canna, S. W., Sallam, T., … Ambati, J. (2021). DDX17 is an essential mediator of sterile NLRC4 inflammasome activation by retrotransposon RNAs. Science immunology, 6(66), eabi4493.PubMed
Verma, S*., Singh, A.*, Varshney, A.*, Chandru, R. A., Acharya, M., Rajput, J., Sangwan, V. S., Tiwari, A. K., Bhowmick, T., & Tiwari, A. (2021). Infectious Keratitis: An Update on Role of Epigenetics. Frontiers in immunology, 12, 765890. PubMed *First author equal contribution
Ambati, M., Apicella, I., Wang, S. B., Narendran, S., Leung, H., Pereira, F., Nagasaka, Y., Huang, P., Varshney, A., Baker, K. L., Marion, K. M., Shadmehr, M., Stains, C. I., Werner, B. C., Sadda, S. R., Taylor, E. W., Sutton, S. S., Magagnoli, J., & Gelfand, B. D. (2021). Identification of fluoxetine as a direct NLRP3 inhibitor to treat atrophic macular degeneration. Proceedings of the National Academy of Sciences of the United States of America, 118(41), e2102975118.PubMed
Fukuda, S., Narendran, S.*, Varshney, A.*, Nagasaka, Y.*, Wang, S. B.*, Ambati, K.*, Apicella, I., Pereira, F., Fowler, B. J., Yasuma, T., Hirahara, S., Yasuma, R., Huang, P., Yerramothu, P., Makin, R. D., Wang, M., Baker, K. L., Marion, K. M., Huang, X., Baghdasaryan, E., … Ambati, J. (2021). Alu complementary DNA is enriched in atrophic macular degeneration and triggers retinal pigmented epithelium toxicity via cytosolic innate immunity. Science advances, 7(40), eabj3658.PubMed *Equal contribution
Narendran, S., Pereira, F., Yerramothu, P., Apicella, I., Wang, S. B., Ambati, K., Hirahara, S., Kim, Y., Ambati, M., Ambati, V. L., Huang, P., Varshney, A., Nagasaka, Y., Fukuda, S., Baker, K. L., Marion, K. M., Deussing, J. M., Sadda, S. R., Gelfand, B. D., & Ambati, J. (2021). Nucleoside reverse transcriptase inhibitors and Kamuvudines inhibit amyloid-β induced retinal pigmented epithelium degeneration. Signal transduction and targeted therapy, 6(1), 149.PubMed
Fukuda, S*., Varshney, A.*, Fowler, B. J., Wang, S. B., Narendran, S., Ambati, K., Yasuma, T., Magagnoli, J., Leung, H., Hirahara, S., Nagasaka, Y., Yasuma, R., Apicella, I., Pereira, F., Makin, R. D., Magner, E., Liu, X., Sun, J., Wang, M., Baker, K., … Ambati, J. (2021). Cytoplasmic synthesis of endogenous Alu complementary DNA via reverse transcription and implications in age-related macular degeneration. Proceedings of the National Academy of Sciences of the United States of America, 118(6), e2022751118.PubMed *First Author equal contribution
2020
Ambati, J., Magagnoli, J., Leung, H., Wang, S. B., Andrews, C. A., Fu, D., Pandey, A., Sahu, S., Narendran, S., Hirahara, S., Fukuda, S., Sun, J., Pandya, L., Ambati, M., Pereira, F., Varshney, A., Cummings, T., Hardin, J. W., Edun, B., Bennett, C. L., … Gelfand, B. D. (2020). Repurposing anti-inflammasome NRTIs for improving insulin sensitivity and reducing type 2 diabetes development. Nature communications, 11(1), 4737.PubMed
Narendran, S., Pereira, F., Yerramothu, P., Apicella, I., Wang, S. B., Varshney, A., Baker, K. L., Marion, K. M., Ambati, M., Ambati, V. L., Ambati, K., Sadda, S. R., Gelfand, B. D., & Ambati, J. (2020). A Clinical Metabolite of Azidothymidine Inhibits Experimental Choroidal Neovascularization and Retinal Pigmented Epithelium Degeneration. Investigative ophthalmology & visual science, 61(10), 4.PubMed
2019
Yadav, S. S., Kumar, M., Varshney, A., & Yadava, P. K. (2019). KLF4 sensitizes the colon cancer cell HCT-15 to cisplatin by altering the expression of HMGB1 and hTERT. Life sciences, 220, 169–176.PubMed
2018
Kerur, N., Fukuda, S., Banerjee, D., Kim, Y., Fu, D., Apicella, I., Varshney, A., Yasuma, R., Fowler, B. J., Baghdasaryan, E., Marion, K. M., Huang, X., Yasuma, T., Hirano, Y., Serbulea, V., Ambati, M., Ambati, V. L., Kajiwara, Y., Ambati, K., Hirahara, S., … Ambati, J. (2018). cGAS drives noncanonical-inflammasome activation in age-related macular degeneration. Nature medicine, 24(1), 50–61.PubMed
Jaiswal, R. K., Varshney, A. K., & Yadava, P. K. (2018). Diversity and functional evolution of the plasminogen activator system. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 98, 886–898.PubMed
2017
Kaur, M., Devi, R., Ghosh, T., Khan, M. M., Kumar, P., Priyanka, Kar, A., Sharma, A., Varshney, A., Kumar, V., & Saxena, S. (2017). Sld5 Ensures Centrosomal Resistance to Congression Forces by Preserving Centriolar Satellites. Molecular and cellular biology, 38(2), e00371-17.PubMed
Ghosh, T*., Varshney, A.*, Kumar, P., Kaur, M., Kumar, V., Shekhar, R., Devi, R., Priyanka, P., Khan, M. M., & Saxena, S. (2017). MicroRNA-874-mediated inhibition of the major G1/S phase cyclin, CCNE1, is lost in osteosarcomas. The Journal of biological chemistry, 292(52), 21264–21281.PubMed Equal Contribution
Varshney, A., Bala, J., Santosh, B., Bhaskar, A., Kumar, S., & Yadava, P. K. (2017). Identification of an RNA aptamer binding hTERT-derived peptide and inhibiting telomerase activity in MCF7 cells. Molecular and cellular biochemistry, 427(1-2), 157–167.PubMed
2015
Kar, A., Kaur, M., Ghosh, T., Khan, M. M., Sharma, A., Shekhar, R., Varshney, A., & Saxena, S. (2015). RPA70 depletion induces hSSB1/2-INTS3 complex to initiate ATR signaling. Nucleic acids research, 43(10), 4962–4974.PubMed
Santosh, B., Varshney, A., & Yadava, P. K. (2015). Non-coding RNAs: biological functions and applications. Cell biochemistry and function, 33(1), 14–22.PubMed
2014
Varshney, A., Ramakrishnan, S. K., Sharma, A., Santosh, B., Bala, J., Yadava, P. K., & Jaiswal, R. K. (2014). Global expression profile of telomerase-associated genes in HeLa cells. Gene, 547(2), 211–217.PubMed
Ramakrishnan, S. K., Varshney, A., Sharma, A., Das, B. C., & Yadava, P. K. (2014). Expression of targeted ribozyme against telomerase RNA causes altered expression of several other genes in tumor cells. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 35(6), 5539–5550.PubMed
2011
Bhaskar, A., Bala, J., Varshney, A., & Yadava, P. (2011). Expression of measles virus nucleoprotein induces apoptosis and modulates diverse functional proteins in cultured mammalian cells. PloS one, 6(4), e18765.PubMed
Bala, J., Bhaskar, A., Varshney, A., Singh, A. K., Dey, S., & Yadava, P. (2011). In vitro selected RNA aptamer recognizing glutathione induces ROS mediated apoptosis in the human breast cancer cell line MCF 7. RNA biology, 8(1), 101–111.PubMed