INTERNATIONAL SPEAKERS
Dr. Ralf Jockers
He is the director and French coordinator of the i-GPCRnet IRN. PhD in biotechnology and biochemistry (Universities of Cologne and Braunschweig; Germany), followed by a postdoctoral training in the laboratory of Dr. AD Strosberg (Paris, France), he is currently INSERM Research Director and group leader at the Institut Cochin (Paris, France). He has a long-term interest in GPCRs in endocrinology and metabolism, including natural receptor variants and GPCR-associated protein complexes. He established the concept of ligand-independent functions of orphan receptors in heterodimers with other receptors and was among the first to discover mitochondrial functions of GPCRs.
PhD in Drug Design (Humboldt-University – Berlin; Germany), and post-doctoral training at University of British Columbia (Vancouver, Canada) she is since 2007 Associate Professor at the Hospital del Mar Research Institute (Barcelone, Spain) and head of the GPCR Drug Discovery Lab. She has a strong involvement in the coordination of European Research Networks in the field of Bioinformatics and GPCRs during the last 10 years.
PhD degree in Pharmaceutical Innovations (University Paul Sabatier Toulouse III, France), with a postdoctoral training at Duke University Medical Center (USA) in Dr. Marc Caron's lab, he is a permanent researcher at the CNRS since 2010. His research activity focus on GPCRs signaling functions in energetic metabolism, obesity-associated disorders, angiogenesis, cancer and schizophrenia. He was the first to identify a FDA-approved compound targeting apelin signaling function that possess anti-angiogenic property, currently used in clinic. He joined the team of Dr. Ralf Jockers at Institut Cochin in Paris to unravel the pathophysiological function of orphan GPCRs.
She holds a PhD in Biochemistry from the University Paris Diderot (France). As a postdoctoral fellow, she joined Pr. Roy Mariuzza’s lab at the Center for Advanced Research in Biotechnology, University of Maryland (USA), where she studied Natural Killer cell receptors, and later joined Dr. R. Jockers’ team at the Institut Cochin in Paris to study membrane receptor function. She is now an INSERM research director and co-leads the "Functional Pharmacology and Pathophysiology of Membrane Receptors" team at the Institut Cochin. Her research combines molecular, cellular and in vivo approaches to study how membrane receptors regulate cell function and their role in obesity and type 2 diabetes, focusing on leptin receptor and GPCRs.
Julien Hanson graduated in Pharmacy at the University of Liège in 2002. He performed a PhD in Medicinal Chemistry at the same University, in the laboratory of Medicinal Chemistry, under the guidance of Jean-Michel Dogné and Bernard Pirotte. In 2007 he joined the Stefan Offermanns lab at the Pharmacology Institute of the University of Heidelberg in Germany for post-doctoral studies. He is now a Senior Research associate of the FRS-FNRS and Principal Investigator of the laboratory of Molecular Pharmacology at the GIGA and CIRM research centers of the University of Liège. His lab investigates the function and signaling of understudied G Protein-Coupled Receptors, principally orphans.
PhD degree in Pharmacology (University of Paris V, France), followed by post-doctoral training in the laboratory of Prof. Thue W. Schwartz (Denmark) and of Dr. Ralf Jockers (Paris, France). Since 2013, she is a permanent researcher at the French National Institute for Medical Research (INSERM) in the laboratory of Dr Ralf Jockers at the Institut Cochin (Paris, France). Her work focus on the melatonin receptor heteromers as potential therapeutic targets, as well as on the development of pharmacological tools to decipher the action mode of ligands and improve ligand selectivity.
PhD in Biochemistry and Molecular Biology (Monash University, Melbourne, Australia), followed by a post-doctoral training in Prof Meritxell Canals and Dr Michelle Halls Laboratory (Monash Institute of Pharmaceutical Sciences (MIPS, Australia), and in Prof. Meritxell Canals and A/Prof. J. Robert Lane Laboratory, University of Nottingham (UK). She is now a Nottingham Research and Anne McLaren Fellow (NRF/AMF) at the University of Nottingham (UK), working on the modulation of G protein-coupled receptors (GPCRs) by Transient Receptor Potential (TRP) channels.
PhD in Physiology in the lab of Dr. Regina P. Markus (Institut of Biosciences, University of Sao Paulo, Brazil), followed by a post-doctoral training in the team of Dr. R. Jockers (Institut Cochin, France). Since 2020 she is Research Associate from the CNRS (Centre National de la Recherche Scientifique, France) in the laboratory of Dr Ralf Jockers at the Institut Cochin (Paris, France). Her main interests are on the development of new technological tools to identify and explore new therapeutic targets to human diseases, focusing on neurodegenerative diseases and metabolic function.
National Speakers
Professor at USP's Department of Clinical and Toxicological Analyses, former ASCB International Affairs Committee President (2020-2022), and Fellow of ASCB and TWAS. Her lab identified four GPCR candidates in Plasmodium, including PfSR25, a potassium sensor triggering Ca²⁺ signaling. Knock-out studies revealed PfSR25-deficient parasites are less resistant to antimalarials, highlighting its potential as a target for new therapies. The primary focus of her research activity is to elucidate how malaria parasites signal in the various stages of their life cycle in efforts to explore new venues for clinical intervention. Her team combines work on live cell microscopy with state-of-the-art molecular techniques. Her laboratory engages in the screening of synthetic and natural compounds aiming to discover new anti-malarial drugs.
Graduated in Pharmacy and Biochemistry (2002), MS (2005), and Ph.D. (2007) in Pharmacology from the University of Sao Paulo, Brazil. Research fellow in the Institute of Infection, Immunity, and Inflammation at the University of Glasgow UK (2008-2011). Currently at Ribeirao Preto Medical School – University of Sao Paulo as a Full Professor in Immunopharmacology, Principal investigator in the Center for Research in Inflammatory Diseases (CRID), and Director of the International Research Laboratory ImunoHealth from CNRS. The research developed by Jose Alves-Filho’s laboratory aims at understanding the cellular and molecular mechanisms regulating differentiation and plasticity of effector and regulatory immune cells and how these can be targeted therapeutically to overcome the pathologic outcome of immune-mediated inflammatory diseases.
Full Professor at the Faculty of Pharmaceutical Sciences of the University of São Paulo; Level 1A Productivity Fellow of CNPq and Full Member of the Brazilian Academy of Sciences. Coordinates regular and thematic projects funded by FAPESP. Has supervised 23 Master's students, 14 Ph.D. students, and 8 postdoctoral researchers. Investigates the mechanisms of innate inflammation control and the mechanisms of immunotoxicity caused by environmental pollutants. Has published 144 papers in international journals, with 3,668 citations and an h-index of 36 (Web of Science) and 43 (Google Scholar).
He has about 15 years of experience in biotechnology, innovation, and venture capital, with a background in biology, human genetics, stem cell biology, and health innovation management. He is passionate about creating and commercializing new technologies that can improve the lives of patients and address global health challenges.
As an Investment Officer at ABIQUIFI, he is responsible for helping the biotech ecosystem in Brazil attract international attention and investment opportunities. Previously, he was the Head of Portfolio Management at EMERGE Brasil, where he supported the development of high-tech academic spin-offs into scalable startup businesses. He also co-founded two biotech companies: LizarBio Therapeutics, a cell therapy company and GeneSeq, a sequencing service company. He has raised and managed over $3M in investment and grants, led cross-functional teams, licensed and managed exclusive technology from top US universities, and participated in several innovation and leadership programs.
Graduated in Pharmacy (generalist curriculum) from the Federal University of Santa Maria (UFSM), Master's and PhD in Pharmacology from the same institution, with sandwich doctorates at Vanderbilt University (Nashville, USA) and Albert Einstein College of Medicine (New York, USA). Two postdoctoral fellowships in the Department of Pharmacology at the University of São Paulo (USP), with a research internship at Stockholm University (Stockholm, Sweden) under the supervision of Jan Nedergaard and Barbara Cannon. He holds a PhD in the Department of Clinical and Toxicological Analysis, Faculty of Pharmaceutical Sciences (FCF), University of São Paulo (USP). Her main research interest is to identify and characterize intracellular peptides capable of modulating parameters related to thermogenesis in adipocytes and brown adipose tissue.
Source: FCF USP
Professor at DCBm/FCFRP-USP, Lucas Tabajara Parreiras e Silva studies intracellular signaling and non-canonical actions of G proteins and GPCRs, with potential pharmaceutical applications. He has a degree in Biological Sciences (UFSCar), a master's degree and a doctorate in Biochemistry (FMRP/USP). He was the researcher responsible for a JP-FAPESP Grant (2017-2021). He maintains collaborations with groups in Canada, Switzerland and Brazil. He uses modern techniques, such as BRET, to investigate the activation and regulation of GPCRs, with the aim of understanding their effects on cell physiology and identifying molecules with greater clinical efficacy and fewer adverse effects.
Professor of the Department of Genetics and Evolutionary Biology of the University of Sao Paulo - Brazil. 15 years of experience in biomedical and biotechnology research. Co-founder of several biotech startups. Scientific advisor for biotech startups. Inventor of several patents in advanced therapies (e.g. oncolytic viral therapy, stem cell-based products, etc), author of several high-impact papers in the field (e.g. Nature, Biofabrication, Cancer Research, etc), and an active member of International Society for Stem Cell Research (ISSCR) and International Society of Cell and Gene Therapy. Currently working in Business Development, connecting the private sector to Academia, and developing partnerships in stem cell-based therapy, bioengineering, gene editing, CAR-T technology, xenotransplantation, cell and gene therapy, and regenerative medicine.
Source: The Goulart Lab website
Adriano D. Andricopulo earned his BSc in Chemistry (1993) from the Federal University of Santa Maria, Brazil, followed by a MSc in Organic Chemistry (1996) from the Federal University of Santa Catarina. He obtained his PhD in Medicinal Chemistry (1999) from the Federal University of Santa Catarina and the University of Michigan, USA. From 1999 to 2002, he conducted postdoctoral research in Medicinal Chemistry at the University of Michigan. He is currently a Full Professor of Medicinal Chemistry at the University of São Paulo (USP), Brazil, with expertise in medicinal chemistry and drug discovery, particularly in neglected tropical diseases, cancer, and the application of artificial intelligence and chemical databases in natural products research.
Veterinary by the Federal University of Bahia (UFBA), Master in Biotechnology from the State University of Feira de Santana (UEFS), PhD from the University of São Paulo and Mednarodna podiplomska šola Jožefa Stefana (2019). Founded of Biolinker, a synthetic biology company working on new ways of expressing and purifying proteins — and providing solutions on top of that. We are working with Covid-19, antimicrobial peptides as biopreservatives, kits for cell-free protein synthesis and protein on-demand.
Source: LinkedIn
Pharmacist and Master from FCFRP-USP, PhD in Biochemistry from IQ-USP and post-doctorate in mass spectrometry. She did internships in Harpenden and Bristol, England and part of her doctorate at Heinrich-Heine University, Dusseldorf, Germany. She completed an MBA in Business Management at FAAP and has experience in research and development projects for new drugs, medicines and cosmetics. She has been a businesswoman and entrepreneur since 2008, and is a founding partner of Lychnoflora, where she acts as business director. She won the “Brazilian Women in Chemistry” award, in the Industrial Leader category, from the American Chemical Society in partnership with the SBQ, in 2022.
Ophthalmologist and Surgeon specializing in Surgical Optics (Laser and Intraocular Lenses), graduated from FMRP-USP. He completed his Medical Residency in Ophthalmology in 1991 at the same institution, and his Master's (1995), Doctorate (1997) and Full Professorship (2003) at the Federal University of São Paulo (UNIFESP). He did part of his PhD at Harvard Medical School and the Massachusetts Institute of Technology, where he was also a Visiting Professor (2012). He is currently an associate professor at UNIFESP's Paulista School of Medicine, where he was Director of the Innovation Agency and Head of its Ophthalmology Department. He is a collaborating professor at the Einstein College of Medicine and Deputy Coordinator of Research for Innovation at FAPESP. He is a mentor, consultant and has founded start-ups in the technology field. He has received 5 awards and/or honors. His lines of research and development are Medical Design, Bioengineering, Physiological Optics, Refractive Surgery and Visual Perception. He founded and coordinates the multidisciplinary open innovation group MedHacker.
Source:LinkedIn
Professor of hematology at USP's Ribeirão Preto Medical School and coordinator of biotechnology and the Advanced Therapies Center (NUTERA) at the Ribeirão Preto Blood Center. He is a member of the Medullary Failure Committee and the Non-Hodgkin's Lymphoma Committee of the ABHH, and of the Brazilian Medullary Failure Group. He is the Principal Investigator of the phase I/II “CARTHEDRALL” multicenter study evaluating the use of anti-CD19 CAR-T cells produced at the Ribeirão Preto Blood Center for the treatment of acute lymphoblastic leukemia (ALL) and non-Hodgkin's lymphoma (NHL). Responsible for conducting cell therapy studies aimed at expanding the application of CAR-T cells to other diseases and the development of other modalities, such as CAR-NK cells.
Full professor of FD-USP. Administrative director of FAPESP.
Graduated in Biomedicine from the Federal University of Pará (1983), Master in Biological Sciences (Microbiology) from the Federal University of Minas Gerais (1991) and PhD in Microbiology and Immunology from the Federal University of São Paulo (1998). She did post-doctoral work at the Federal University of São Paulo from 1999-2001. She is currently Full Professor and Head of the Department of Clinical and Toxicological Analysis at the Faculty of Pharmaceutical Sciences of the University of São Paulo (FCF-USP). She chairs the Faculty's Institutional Academic Planning Committee. She works in the area of Parasite Protozoology, specifically in human malaria. Her current projects are focused on pre-clinical tests for vaccination against malaria caused by Plasmodium vivax. She is a member of the National Institute of Vaccine Science and Technology (INCTV) and the Vaccine Research Support Center (NAP, PRP-USP).
Source: FCF USP