By the end of this session, you should be able to:
Define critical care and understand the role of the ICU
Identify common indications for ICU admission
Understand monitoring and organ support in ICU
Learn principles of sedation and analgesia in critically ill patients
Recognise the importance of infection control and nutrition
Critical care is the comprehensive, continuous care of critically ill patients who are at risk of or recovering from life-threatening organ failure.
This care is delivered in an Intensive Care Unit (ICU) or High Dependency Unit (HDU).
Respiratory failure
Need for mechanical ventilation (e.g. ARDS, pneumonia, COPD)
Cardiovascular instability
Requiring vasopressors/inotropes (e.g. septic shock, MI)
Neurological impairment
GCS ≤ 8, seizures, stroke, traumatic brain injury
Multiorgan failure
Postoperative monitoring
Especially after major surgery or massive blood loss
Severe metabolic derangement
DKA, HHS, severe acidosis
Sepsis
Level
Description
Level 0
Standard ward care
Level 1
Patients at risk of deterioration (HDU)
Level 2
Single organ support (e.g. NIV, inotropes)
Level 3
Multiple organ support (e.g. mechanical ventilation + vasopressors) – full ICU
Category
Parameters
Cardiovascular
HR, BP (invasive/non-invasive), CVP, MAP
Respiratory
SpO₂, RR, PaO₂/PaCO₂, ventilator parameters
Neurological
GCS, pupil size/reactivity, EEG if indicated
Renal
Urine output (>0.5 mL/kg/hr), urea/creatinine
Metabolic
Blood glucose, electrolytes, lactate
Temperature
Continuous or intermittent monitoring
Others
Arterial blood gases (ABG), ECG, fluid balance charts
Oxygen therapy
Non-invasive ventilation (NIV) – CPAP, BiPAP
Mechanical ventilation
Modes: Volume/pressure control, SIMV, pressure support
PEEP to maintain alveolar patency
Vasopressors:
Noradrenaline: 0.05–1 mcg/kg/min IV (1st line in septic shock)
Adrenaline: 0.05–2 mcg/kg/min IV
Phenylephrine: 0.1–0.5 mcg/kg/min IV
Inotropes:
Dobutamine: 2–20 mcg/kg/min (esp. in heart failure)
Dopamine: dose-dependent action
Maintain fluid balance
Monitor urine output
Dialysis/CRRT for renal failure
Goals:
Ensure patient comfort
Facilitate mechanical ventilation
Reduce anxiety, pain, agitation
Drug
Dose
Notes
Midazolam
0.02–0.1 mg/kg/hr
Short-acting benzodiazepine
Propofol
0.5–4 mg/kg/hr
Rapid onset, hypotension risk
Dexmedetomidine
0.2–0.7 mcg/kg/hr
Alpha-2 agonist, mild analgesia, minimal resp. depression
Fentanyl: 1–2 mcg/kg/hr IV
Morphine: 2–5 mg IV bolus, or infusion 0.5–2 mg/hr
Paracetamol: 1 g IV every 6 hours
Always assess with sedation scales (e.g. RASS) and titrate to effect.
Start enteral nutrition within 24–48 hours if gut is functional
Parenteral nutrition if enteral not possible
Monitor:
Calories
Proteins
Electrolytes and blood glucose
Strict hand hygiene
Aseptic technique during catheter insertion
Daily review of:
Lines (central/peripheral)
Urinary catheters
Antibiotics
Ventilator-Associated Pneumonia (VAP) prevention:
Head elevation 30–45°
Oral care
Regular suctioning
Informed consent
Discuss goals of care and prognosis
End-of-life decisions (e.g. DNR orders, withdrawal of care)