UK NK meeting 2025 - January 7th
9:30-10:00 – Arrival/registration/Coffee
10:00 – 10:10 – Malcolm Sim & Eric O'Neill (Oxford) - Welcome
10:10 – 11:00 – Karl-Johan Malmberg (Oslo) - Keynote lecture
11:00-12:45 – NK cells and Cancer
11:00 – 11:25 – Leo Carlin & Demi Brownlie (Glasgow) - Pulmonary Natural Killer cell - Neutrophil interactions in Inflammation and Cancer
11:25 – 11:45 - Mihaela Lorger (Leeds) – Natural killer cells are critical for the efficacy of immune checkpoint blockade in brain metastases
11:45: – 12:05 – Nadia Guerra (ICL) - NK Cell Dynamics in Tumour Immunity
12:05 – 12:15 - Stephanie Kucykowicz (UCL) - Hepatocellular carcinoma drives pathways promoting NK cell suppression of T cells within the tumour niche
12:15 – 12:25 – Lara Graham (Southampton) - NK cell-mediated ADCC is suppressed by lymph node microenvironmental signals in B cell malignancies
12:25 – 12:45– Hugh Brady (ICL) – A new platform generating large-scale production of highly cytotoxic human NK cells for cancer immunotherapy
12:45 - 13:45 – Lunch
13:45-15:05 – NK cells and Pathogens
13:45 – 14:00 – Sam Chamberlain (Oxford) - RIFINs displayed on malaria-infected erythrocytes bind both KIR2DL1 and KIR2DS1
14:00 – 14:15 - Hannah Preston (Cardiff) - Controlling HCMV Through NK-dependent ADCC-inducing Immunotherapies.
14:15 – 14:30 - Helen R. Wagstaffe (ICL) - Less differentiated, NKG2C - NK cells were associated with protection against controlled human SARS-CoV-2 infection in seronegative adults
14:30 – 14:45 – Jonida Kokici (UCL) – Selective harnessing of adaptive NK cells for functional HBV cure
14:45 – 15:05 – Simon Kollnberger (Cardiff) – Human cytomegalovirus encodes a hypervariable immunoevasin that binds killer cell immunoglobulin-like receptors
15:05-15:40 – Coffee/Tea break
15:40 – 16:45 – NK cells in Tissues
15:40-16:00 – Victoria Male (ICL) - Tissue-resident NK cells in the control of HCMV
16:00 – 16:15 – Bonnie Ng (Southampton) - Women with recurrent miscarriage have altered uterine natural killer cell receptor expression profiles
16:15 – 16:30 - Harry Persaud (UCL) - The role of kidney-resident natural killer cells in the control of human cytomegalovirus and BK virus infections
16:30 – 16:45 - Giampiero Valenzano (Oxford) - In vitro generation of tissue-resident NK cells for cancer immunotherapy
16:50 – 17:00 – prizes
17:00 – 18:00 – drinks/snacks