Current Research Projects at the Unhas Fly Research Group (UFRG)
Exploration of the Use of Mutant and Transgenic Drosophila as High-Throughput In Vivo Pharmacological Models to Enhance Drug Repurposing Research Capacity
Objective: To utilize mutant and transgenic Drosophila as high-throughput in vivo models to enhance the efficiency and capacity of drug repurposing research. This involves leveraging these models to rapidly screen and evaluate the pharmacological effects of existing drugs, identify new therapeutic uses, and improve the overall drug repurposing process.
Funding: Penelitian Fundamental Kolaboratif 2024 (UNHAS)
High-Throughput In Vivo Screening of Indonesian Natural Plant Extracts for Managing Diabetes and Infection Complications Using a Double Burden Disease Model
Objective: To conduct high-throughput in vivo screening of natural plant extracts from Indonesian sources to evaluate their effectiveness in managing diabetes and associated infection complications. This involves establishing a double-burden disease model to assess the therapeutic potential and efficacy of these extracts in simultaneously addressing both diabetes and infection.
Funding: Penelitian Dasar Fundamental 2024 (DRTPM)
Exploration of the Therapeutic Potential of Sulawesi Ethnopharmaceuticals for Diabetes: A High-Throughput Screening Approach in Drosophila Models and Translation to Mammalian Models
Objective: To evaluate the therapeutic potential of ethnopharmaceuticals from Sulawesi for diabetes through a high-throughput screening approach using Drosophila models. The study aims to identify promising compounds and subsequently translate the findings to mammalian models to assess their effectiveness and potential for clinical application in managing diabetes.
Funding: Penelitian KATALIS 2024 (DRTPM)
In response to the COVID-19 pandemic situation, we also actively collaborate with several national and international researchers to explore different aspects of diseases.