Eun Ran Kim, Jeong Su Park, Jin Hee Kim, Ji Young Oh, In Jeong Oh, Da Hyun Choi, Yu Seol Lee, I Seul Park, SeungWon Kim, Da Hyun Lee, Jae Hee Cheon, Jin-Woo Bae, Minyoung Lee, Jin Won Cho, In Bok An, Eun Joo Nam, Sang-In Yang, Myung-Shik Lee, Soo Han Bae, Yong-ho Lee
A GLP-1/GLP-2 receptor dual agonist to treat NASH: Targeting the gut- liver axis and microbiome. Hepatology 2022, In Press [IF=17.425]
Kim SR, Lee SG, Kim SH, Kim JH, Choi E, Cho W, Rim JH, Hwang I, Lee CJ, Lee M, Oh CM, Jeon JY, Gee HY, Kim JH, Lee BW, Kang ES, Cha BS, Lee MS, Yu JW, Cho JW, Kim Jung Sun, Yong-ho Lee
SGLT2 inhibition modulates NLRP3 inflammasome activity via changes in ketones and insulin in diabetes and cardiovascular disease. Nature communications 2020;11:2127. [IF=12.121]
Yong-ho Lee, Kim SR, Han DH, Yu HT, Han YD, Kim JH, Kim SH, Lee CJ, Min BH, Kim DH, Kim KH, Cho JW, Lee WW, Shin EC, Park S.
Senescent T Cells Predict the Development of Hyperglycemia in Humans. Diabetes 2019;68(1):156-162. [IF=25.083]
Kim SH, Kim G, Han DH, Lee M, Kim I, Kim B, Kim KH, Song YM, Yoo JE, Wang HJ, Bae SH, Yong-ho Lee (Corres), Lee BW, Kang ES, Cha BS, Lee MS.
Ezetimibe ameliorates steatohepatitis via AMP activated protein kinase-TFEB-mediated activation of autophagy and NLRP3 inflammasome inhibition. Autophagy 2017;13:1767–1781. [IF=16.016]
Lee HH, Yong-ho Lee (Co-corres), Kim SU, Kim HC.
Metabolic Dysfunction-Associated Fatty Liver Disease and Incident Cardiovascular Disease Risk: A Nationwide Cohort Study. Clin Gastroenterol Hepatol. 2021;19:2138–2147. [IF=11.382]
Han E, Yong-ho Lee (Co-corres), Kim YD, Kim BK, Park JY, Kim DY, Ahn SH, Lee BW, Kang ES, Cha BS, Han KH, Nam HS, Heo JH, Kim SU.
Nonalcoholic Fatty Liver Disease and Sarcopenia Are Independently Associated With Cardiovascular Risk. Am J Gastroenterol 2020;115:584–595. [IF=10.171]
Yong-ho Lee, Kim KJ, Yoo Me, Kim G, Yoon H, Jo K, Youn JC, Yun M, Park JY, Shim CY, Lee BW, Kang SM, Ha JW, Cha BS, Kang ES. Association of nonalcoholic steatohepatitis with subclinical myocardial dysfunction in non-cirrhotic patients. Journal of Hepatology 2018;68:764–772. [IF=25.083]
Yong-ho Lee, Kim SU, Song K, Park JY, Kim DY, Ahn SH, Lee BW, Kang ES, Cha BS, Han KH.
Sarcopenia Is Associated With Significant Liver Fibrosis Independently of Obesity and Insulin Resistance in Nonalcoholic Fatty Liver Disease: Nationwide Surveys (KNHANES 2008-2011). Hepatology 2016;63:776-786. [IF=17.425]
Yong-ho Lee, Jung KS, Kim SU, Yoon H, Yun YJ, Lee BW, Kang ES, Han KH, Lee HC, Cha BS.
Sarcopaenia is associated with NAFLD independently of obesity and insulin resistance: nationwide surveys (KNHANES 2008–2011). Journal of Hepatology 2015;63:486-493. [IF=25.083]
Hye-Jun Kil, Jang Hyeon Kim, Kanghae Lee, Tae-Uk Kang, Ju-Hyun Yoo, Yong-ho Lee, Jin-Woo Park
A self-powered and supercapacitive microneedle continuous glucose monitoring system with a wide range of glucose detection capabilities
Biosensors and Bioelectronics 257(2024)116297. [IF=10.7]
A Young Sim, Da Hyun Choi, Jong Youl Kim, Eun Ran Kim, A-ra Goh, Yong-ho Lee, Jong Eun Lee
SGLT2 and DPP4 inhibitors improve Alzheimer’s disease–like pathology and cognitive function through distinct mechanisms in a T2D–AD mouse model. Biomedicine & Pharmacotherapy 168(2023)115755. [IF=7.419]
Hye Jin Chun, Eun Ran Kim, Minyoung Lee, Da Hyun Choi, Soo Hyun Kim, Eugene Shin, Jin-Hong Kim, Jin Won Cho, Dai Hoon Han, Bong-Soo Cha, Yong-ho Lee
Increased expression of sodium-glucose cotransporter 2 and O-GlcNAcylation in hepatocytes drives non-alcoholic steatohepatitis. Metabolism: Clinical and Experimental 145(2023)155612. [IF=13.934]
Eun Ran Kim, Jeong Su Park, Jin Hee Kim, Ji Young Oh, In Jeong Oh, Da Hyun Choi, Yu Seol Lee, I Seul Park, SeungWon Kim, Da Hyun Lee, Jae Hee Cheon, Jin-Woo Bae, Minyoung Lee, Jin Won Cho, In Bok An, Eun Joo Nam, Sang-In Yang, Myung-Shik Lee, Soo Han Bae, Yong-ho Lee
A GLP-1/GLP-2 receptor dual agonist to treat NASH: Targeting the gut- liver axis and microbiome. Hepatology 2022, In Press [IF=17.425]
Chan Joo Lee # 1, Ji-Yeon Lee # 2, Kyungdo Han 1 3, Da Hye Kim 1 4, Hanna Cho 5, Kwang Joon Kim 6, Eun Seok Kang 2 7, Bong-Soo Cha 2 7, Yong-Ho Lee 2 7, Sungha Park.
Blood Pressure Levels and Risks of Dementia: a Nationwide Study of 4.5 Million People. Hypertension. 2022 Jan;79(1):218-229
Lee HH, Yong-ho Lee (Co-corres), Kim SU, Kim HC.
Metabolic Dysfunction-Associated Fatty Liver Disease and Incident Cardiovascular Disease Risk: A Nationwide Cohort Study. Clin Gastroenterol Hepatol. 2021;19:2138–2147. [IF=11.382]
Kim SR, Lee SG, Kim SH, Kim JH, Choi E, Cho W, Rim JH, Hwang I, Lee CJ, Lee M, Oh CM, Jeon JY, Gee HY, Kim JH, Lee BW, Kang ES, Cha BS, Lee MS, Yu JW, Cho JW, Kim Jung Sun, Yong-ho Lee
SGLT2 inhibition modulates NLRP3 inflammasome activity via changes in ketones and insulin in diabetes and cardiovascular disease. Nature communications 2020;11:2127. [IF=12.121]
Han E, Yong-ho Lee (Co-corres), Kim YD, Kim BK, Park JY, Kim DY, Ahn SH, Lee BW, Kang ES, Cha BS, Han KH, Nam HS, Heo JH, Kim SU.
Nonalcoholic Fatty Liver Disease and Sarcopenia Are Independently Associated With Cardiovascular Risk. Am J Gastroenterol 2020;115:584–595. [IF=10.171]
Bae J, Hong N, Lee BW, Kang ES, Cha BS Lee YH (Corres). Comparison of Renal Effects of Ezetimibe-Statin Combination versus Statin Monotherapy: A Propensity-Score-Matched Analysis. Journal of Clinical Medicine 2020 Mar 15;9(3):798.
[REPLY] Lee J-Y, Lee YH (Corres). Response to Letter to the Editor: “Risk of Incident Dementia According to Metabolic Health and Obesity Status in Late Life: A Population-Based Cohort Study” J Clin Endocrinol Metab, February 2020, 105(2):573–574.
[EDITORIAL] Lee YH, Kim SU. Sarcopenia: an emerging risk factor for non‑alcoholic fatty liver disease. Hepatology International (2020) 14:5–7.
Han E, Lee JY, Han KD, Cho H, Kim KJ, Lee BW, Kang ES, Cha BS, Zobair M Younossi, Lee YH (Corres), Gamma glutamyltransferase and risk of dementia in prediabetes and diabetes. Scientific reports (2020) 10:6800.
Lee HH, Cho Y, Choi YJ, Huh BW, Lee BW, Kang ES, Park SW, Cha BS, Lee EJ, Lee YH (Corres), Huh KB. Non-alcoholic steatohepatitis and progression of carotid atherosclerosis in patients with type 2 diabetes: a Korean cohort study. Cardiovasc Diabetol (2020) 19:81.
Kyung Hyun Kim 1, Dong Jin Joo 2, Yong-Ho Lee 3, Beom Kyung Kim 4, Jun Yong Park 4, Do Young Kim 4, Sang Hoon Ahn 4, Kwang-Hyub Han 4, Seung Up Kim 5 Association between liver fibrosis and appendicular skeletal muscle mass during antiviral therapy in chronic hepatitis B. Dig Liver Dis. 2020 Nov;52(11):1338-1345.
Yong-ho Lee, Kim SR, Han DH, Yu HT, Han YD, Kim JH, Kim SH, Lee CJ, Min BH, Kim DH, Kim KH, Cho JW, Lee WW, Shin EC, Park S.
Senescent T Cells Predict the Development of Hyperglycemia in Humans. Diabetes 2019;68(1):156-162. [IF=25.083]
Kim JH, Lee M, Kim SH, Kim SR, Lee BW, Kang ES, Cha BS, Cho JW, Lee YH (Corres). Sodium-glucose cotransporter 2 inhibitors regulate ketone body metabolism via inter-organ crosstalk. Diabetes, Obesity and Metabolism. 2019;21:801–811. [IF=5.98] Selected as a cover image.
63. Lee YH (co-first), Kim SR, Han DH, Yu HT, Han YD, Kim JH, Kim SH, Lee CJ, Min BH, Kim DH, Kim KH, Cho JW, Lee WW, Shin EC, Park S. Senescent T Cells Predict the Development of Hyperglycemia in Humans. Diabetes. 2019;68(1):156-162. [IF=7.273]
64. Lee JY, Han K, Han E, Kim G, Cho H, Kim KJ, Lee BW, Kang ES, Cha BS, Brayne C, Lee YH (Corres). Risk of Incident Dementia According to Metabolic Health and Obesity Status in Late-life: a Population-based Cohort Study. Journal of Clinical Endocrinology & Metabolism. 2019;104(7):2942-2952. [IF=5.789]
65. Kim G, Lee SG, Lee BW, Kang ES, Cha BS, Ferrannini E, Lee YH (Co-corres), Cho NH. Spontaneous ketonuria and risk of incident diabetes: a 12- year prospective study Diabetologia. 2019;62:779–788. [IF=6.023] Selected as Editor’s Choice.
66. Lee DH, Lee B, Park JS, Lee YS, Kim JH, Cho Y, Jo Y, Kim HS, Lee YH (Co-corres), Nam KT, Bae SH. Inactivation of Sirtuin2 protects mice from acetaminophen-induced liver injury: possible involvement of ER stress and S6K1 activation. BMB Reports. 2019; 52(3): 190-195.
67. Lee YH, Cho Y, Lee BW, Park CY, Lee DH, Cha BS, Rhee EJ. Nonalcoholic Fatty Liver Disease in Diabetes. Part I: Epidemiology and Diagnosis. Diabetes Metab J. 2019;43(1):31-45. [REVIEW]
68. Lee H, Kim G, Choi YJ, Huh BW, Lee BW, Kang ES, Cha BS, Lee EJ, Lee YH (Corres), Huh KB. Association between Non-Alcoholic Steatohepatitis and Left Ventricular Diastolic Dysfunction in Type 2 Diabetes Mellitus. Diabetes Metab J. 2020;44:267-276.
69. Kim G, Yoo M, Hong MH, Lee BW, Kang ES, Cha BS, Kim HR, Lee YH (Co-corres), Cho BC. Predictive factors for the development of diabetes in cancer patients treated with phosphatidylinositol 3‑kinase inhibitors. Cancer Chemotherapy and Pharmacology 2019;84:405–414.
70. Lee YH, Kim J, Park K, Lee MS β-cell autophagy: Mechanism and role in β-cell dysfunction. Molecular Metabolism. 2019;27S:S92-S103.
Yong-ho Lee, Kim KJ, Yoo Me, Kim G, Yoon H, Jo K, Youn JC, Yun M, Park JY, Shim CY, Lee BW, Kang SM, Ha JW, Cha BS, Kang ES. Association of nonalcoholic steatohepatitis with subclinical myocardial dysfunction in non-cirrhotic patients. Journal of Hepatology 2018;68:764–772. [IF=25.083]
56. Choe EY, Lee YH (co-Corres), Choi YJ, Huh BW, Lee BW, Kim SK, Kang ES, Cha BS, Lee EJ, Huh KB, Younossi ZM. Waist-to-calf ratio is an independent predictor of hepatic steatosis and fibrosis patients with type 2 diabetes. Journal of Gastroenterology and Hepatology. 2018;33(5):1082-1091. [IF=3.483]
57. Han E, Lee YH (co-first), Kim BK, Park JY, Kim DY, Ahn SH, Lee BW, Kang ES, Cha BS, Han KH, Kim SU. Sarcopenia is associated with the risk of significant liver fibrosis in metabolically unhealthy subjects with chronic hepatitis B. Alimentary pharmacology & therapeutics
2018;48(3):300-312. [IF=7.357]
58. Lee YH (co-first), Hong N, Lee CJ, Park SH, Lee BW, Cha BS, Kang ES. Differential association of ezetimibe-simvastatin combination with major adverse cardiovascular events in patients with or without diabetes: a retrospective propensity score-matched cohort study. Scientific Reports 2018;8(1):11925 [IF=4.122]
59. Yim J, Kim G, Lee BW, Kang ES, Cha BS, Kim JH, Cho JW, Lee SG, Lee YH (co-Corres). Relationship Between Circulating Netrin-1 Concentration, Impaired Fasting Glucose, and Newly Diagnosed Type 2 Diabetes. Frontiers in Endocrinology (Lausanne). 2018;9:691.
60. Lee JY, Hong N, Kim HR, Lee BW, Kang ES, Cha BS, Lee YH (Corres). Effects of Serum Albumin, Calcium Levels, Cancer Stage and Performance Status on Weight Loss in Parathyroid Hormone-Related Peptide Positive or Negative Patients with Cancer. Endocrinology and metabolism 2018;33(1):97-104.
61. Hong N, Lee YH (co-first), Tsujita K, Gonzalez JA, Kramer CM, Kovarnik T, Kouvelos GN, Suzuki H, Han K, Lee CJ, Park SH, Lee BW, Cha BS, Kang ES. Comparison of the Effects of Ezetimibe-Statin Combination Therapy on Major Adverse Cardiovascular Events in Patients with and without Diabetes: A Meta-Analysis. Endocrinology and metabolism 2018;33(2):219-227.
Kim SH, Kim G, Han DH, Lee M, Kim I, Kim B, Kim KH, Song YM, Yoo JE, Wang HJ, Bae SH, Yong-ho Lee (Corres), Lee BW, Kang ES, Cha BS, Lee MS.
Ezetimibe ameliorates steatohepatitis via AMP activated protein kinase-TFEB-mediated activation of autophagy and NLRP3 inflammasome inhibition. Autophagy 2017;13:1767–1781. [IF=16.016]
Kim SR, Lee YH (co-first), Lee SG, Lee SH, Kang ES, Cha BS, Lee HC , Kim JH, Lee BW. Morning Spot Urine Glucose-to-Creatinine Ratios Predict Overnight Urinary Glucose Excretion in Patients With Type 2 Diabetes. Ann Lab Med. 2017;37(1):9-17.
44. Lee EY, Lee YH (co-first), Jin SM, Yang HK, Jung CH, Park CY, Cho JH, Lee WJ, Lee BW, Kim JH. Differential association of body mass index on glycemic control in type 1 diabetes. Diabetes Metab Res Rev. 2017;33: e2815.
45. Kim G, Lee YH (co-Corres), Jeon JY, Bang H, Lee BW, Kang ES, Lee IK, Cha BS, Kim CS. Increase in resting heart rate over 2 years predicts incidence of diabetes: A 10-year prospective study. Diabetes Metab. 2017;43:25–32. [IF=4.101]
46. Lee YH (co-first), Kim JH, Kim SR, Jin HY, Rhee EJ, Cho YM, Lee BW. Lobeglitazone, a Novel Thiazolidinedione, Improves Non-Alcoholic Fatty Liver Disease in Type 2 Diabetes: Its Efficacy and Predictive Factors Related to Responsiveness. J Korean Med Sci 2017;32:60-69.
47. Kim SR, Lee YH (co-Corres), Kang ES, Cha BS, Lee BW. The Relationship between Increases in Morning Spot Urinary Glucose Excretion and Decreases in HbA1C in Patients with Type 2 Diabetes After Taking an SGLT2 Inhibitor: A Retrospective, Longitudinal Study. Diabetes Ther. 2017 8:601–609.
48. Han E, Lee YH (co-first), Lee BW, Kang ES, Cha BS. Pre-sarcopenia is associated with renal hyperfiltration independent of obesity or insulin resistance: Nationwide Surveys (KNHANES 2008-2011). Medicine (Baltimore). 2017;96:e7165. [IF=1.807]
49. Kim G, Lee YH (co-Corres), Lee BW, Kang ES, Lee IK, Cha BS, Kim DJ. Diabetes self-assessment score and the development of diabetes: A 10-year prospective study. Medicine (Baltimore). 2017;96:e7067. [IF=1.807]
50. Han E, Lee YH (Corres), Lee BW, Kang ES, Lee IK, Cha BS. Anatomic fat depots and cardiovascular risk: a focus on the leg fat using nationwide surveys (KNHANES 2008-2011). Cardiovasc Diabetol. 2017;16:54. [IF=4.752]
51. Lee EY, Lee YH (co-first), Yi SW, Shin SA, Yi JJ. BMI and All-Cause Mortality in Normoglycemia, Impaired Fasting Glucose, Newly Diagnosed Diabetes, and Prevalent Diabetes: A Cohort Study. Diabetes Care. 2017;40:1026–1033. [IF=13.397]
53. Kim HM, Lee YH (co-first), Han K, Lee BW, Kang ES, Kim J, Cha BS. Impact of diabetes mellitus and chronic liver disease on the incidence of dementia and all-cause mortality among patients with dementia. Medicine (Baltimore). 2017;96(47):e8753. [IF=2.028]
54. Han E, Lee YH (Corres). Non-Alcoholic Fatty Liver Disease: The Emerging Burden in Cardiometabolic and Renal Diseases Diabetes Metab J 2017;41:430-437 [Invited REVIEW, IF=3.710].
Yong-ho Lee, Kim SU, Song K, Park JY, Kim DY, Ahn SH, Lee BW, Kang ES, Cha BS, Han KH.
Sarcopenia Is Associated With Significant Liver Fibrosis Independently of Obesity and Insulin Resistance in Nonalcoholic Fatty Liver Disease: Nationwide Surveys (KNHANES 2008-2011). Hepatology 2016;63:776-786. [IF=17.425]
Lee YH (co-first), MR Yun, HM Kim, BH Jeon, BC Park, BW Lee, ES Kang, HC Lee, YW Park, BS Cha. Exogenous administration of DLK1 ameliorates hepatic steatosis and regulates gluconeogenesis via activation of AMPK. International Journal of Obesity 2016;40:356–365. [IF=5.487]
33. Hong NK, Yoon HJ, Lee YH (Corres), Kim HR, Lee BW, Kang ES, Cha BS, Lee HC. Serum PTHrP predicts weight loss in cancer patients independent of hypercalcemia, inflammation, and tumor burden. Journal of Clinical Endocrinology and Metabolism 2016;101:1207-1214. [IF=5.455]
34. Kim G, Lee YH (co-first), Han MH, Lee EK, Kim CH, Kwon HS, Jeong IK, Kang ES, Kim DJ. Economic Burden of Hypoglycemia in Patients with Type 2 Diabetes Mellitus from Korea. PLoS One 2016;11: e0151282.
35. Rim JH, Lee YH (co-first), Lee MH, Kim HY, Choi J, Lee BW, Kang ES, Lee HC, Kim JH, Lee SG, Cha BS. Comparison and Validation of 10 Equations Including a Novel Method for Estimation of LDL-cholesterol in a 168,212 Asian Population. Medicine (Baltimore) 2016;95:e3230. [IF=2.133]
36. Lee YH, Lee SG, Lee CJ, Kim SH, Song YM, Yoon MR, Jeon BH, Lee JH, Lee BW, Kang ES, Lee HC, Cha BS. Association between betatrophin/ANGPTL8 and non-alcoholic fatty liver disease: animal and human studies. Scientific reports 2016;6:24013. [IF=5.228]
37. Lee YH, Cha BS. Reply to "The association between sarcopenia and non-alcoholic fatty liver disease: Potential pitfalls in non-invasive prediction models". Journal of Hepatology 2016;64:520-521. [Letter]
38. Han E, Kim G, Hong N, Lee YH (co-Corres), Kim DW, Shin HJ, Kang ES, Lee BW, Lee IK, Cha BS. Association between dietary acid load and the risk of cardiovascular disease: nationwide surveys (KNHANES 2008-2011). Cardiovasc Diabetol. 2016;15:122. [IF=4.752]
39. Han E, Lee YH (co-first), Kim G, Kim SR, Lee BW, Kang ES, Ahn CW, Cha BS. Sarcopenia is associated with albuminuria independently of hypertension and diabetes: KNHANES 2008-2011. Metabolism. 2016;65(10):1531-40. [IF=5.777]
40. Kim G, Lee YH (co-first), Kang ES, Cha BS, Lee HC, Lee BW. Characteristics Predictive for a Successful Switch from Insulin Analogue Therapy to Oral Hypoglycemic Agents in Patients with Type 2 Diabetes. Yonsei Med J. 2016;57(6):1395-403.
41. Lee DH, Han DH, Nam KT, Park JS, Kim SH, Lee M, Kim G, Min BS, Cha BS, Lee YS, Sung SH, Jeong H, Ji HW, Lee MJ, Lee JS, Lee HY, Chun Y, Kim J, Komatsu M, Lee YH (Co-Corres), Bae SH. Ezetimibe, an NPC1L1 inhibitor, is a potent Nrf2 activator that protects mice from diet-induced nonalcoholic steatohepatitis. Free radical biology & medicine. 2016;99:520-532. [IF=5.606]
42. Lee YH, Han K, Ko SH, Ko KS, Lee KU; Taskforce Team of Diabetes Fact Sheet of the Korean Diabetes Association. Data Analytic Process of a Nationwide Population-Based Study Using National Health Information Database Established by National Health Insurance Service. Diabetes Metab J. 2016;40:79-82.
Yong-ho Lee, Jung KS, Kim SU, Yoon H, Yun YJ, Lee BW, Kang ES, Han KH, Lee HC, Cha BS.
Sarcopaenia is associated with NAFLD independently of obesity and insulin resistance: nationwide surveys (KNHANES 2008–2011). Journal of Hepatology 2015;63:486-493. [IF=25.083]
24. Yoon HJ, Lee YH (co-first), Kim SR, Rim TH, Lee EY, Kang ES, Cha BS, Lee HC, Lee BW. Glycated albumin and the risk of micro- and macrovascular complications in subjects with Type 1 Diabetes. Cardiovascular Diabetology 2015;14:53. [IF=4.752]
25. Kim G, Lee YH (co-first), Park YM, Kim J, Kim, H, Lee BW, Kang ES, Cha BS, Lee HC, Kim DJ. Use of a Diabetes Self-Assessment Score to Predict Nonalcoholic Fatty Liver Disease and Nonalcoholic Steatohepatitis. Medicine (Baltimore) 2015; 94: e1103. [IF=5.723]
26. Lee YH, EJ Armstrong, G Kim, J Oh, Kang SM, Lee BW, Ahn CW, Cha BS, Lee HC, CS Mantzoros, Kang ES. Undiagnosed diabetes is prevalent in younger adults and associated with a higher risk cardiometabolic profile compared to diagnosed diabetes. American Heart Journal 2015;170:760-769. [IF=4.436]
27. Lee YH, Dipeptidyl Peptidase-4 Inhibitor Alarms: Is Heart Failure Caused by a Class Effect. Diabetes & Metabolism Journal 2015;39(3):204-206. [Editorial]
28. Jeon BH, Lee YH (co-first), Yun MR, Kim SH, Lee BW, Kang ES, Lee HC, Cha BS. Increased expression of ATP-binding cassette transporter A1 (ABCA1) as a possible mechanism for the protective effect of cilostazol against hepatic steatosis. Metabolism, clinical and experimental 2015;64:1444–53. [IF=4.375]
29. Yoon HJ, Lee YH (co-first), Kim KJ, Kim SR, Kang ES, Cha BS, Lee HC, Lee BW Glycated Albumin Levels in Patients with Type 2 Diabetes Increase Relative to HbA1c with Time. BioMed Research International 2015;2015:Article ID 576306.
30. Lee EY, Lee YH (Corres), Kim SH, Chung KS, Kwon O, Kim BS, Nam CM, Park CS, Lee BW, Kang ES, Cha BS, Lee HC. Association between heme oxygenase-1 promoter polymorphisms and the development of albuminuria in type 2 diabetes: A case-control study. Medicine (Baltimore) 2015;94(43):e1825. [IF=1.804]
21. Cho Y, Choe E, Lee YH (co-first), Seo JW, Choi Y, Yun Y, Wang HJ, Ahn CW, Cha BS, Lee HC, Kang ES. Risk of diabetes in patients treated with HMG-CoA reductase inhibitors. Metabolism, clinical and experimental 2015;64:482-488. [IF=4.375]
22. Lee YH, Lee CJ, Lee HS, Choe EY, Lee BW, Ahn CW, Cha BS, Lee HC, Balkau B, Kang ES. Comparing kidney outcomes in type 2 diabetes treated with different sulphonylureas in real-life clinical practice. Diabetes and Metabolism 2015;41:208-215. [IF=4.101]
Yong-ho Lee, Lee S, Lee MH, Kim J, Lee BW, Kang ES, Lee HC, Cha BS. Serum cholesterol concentration and prevalence, awareness, treatment, and control of high low-density lipoprotein cholesterol in the Korea national health and nutrition examination surveys 2008-2010: beyond the tip of the iceberg. Journal of the American Heart Association 2014;3:446. [IF=4.863]
18. Lee YH, Kim JE, Roh YH, Choi HR, Rhee Y, Kang DR, Lim SK. The Combination of Vitamin D Deficiency and Mild to Moderate Chronic Kidney Disease Is Associated With Low Bone Mineral Density and Deteriorated Femoral Microarchitecture: Results From the KNHANES 2008–2011. Journal of Clinical Endocrinology and Metabolism 2014;99:3879-88. [IF=5.531]
19. Lee YH, Bang H, Park YM, Bae JC, Lee BW, Kang ES, Cha BS, Lee HC, Balkau B, Lee WY, Kim DJ. Non-laboratory-based self-assessment screening score for non-alcoholic fatty liver disease: development, validation and comparison with other scores. PLoS One. 2014; 9(9):e107584.
20. Lee YH, Kown MH, Kim KJ, Lee EY, Kim D, Lee BW, Kang ES, Cha BS, Lee HC. Inverse Association between Glycated Albumin and Insulin Secretory Function May Explain Higher Levels of Glycated Albumin in Subjects with Longer Duration of Diabetes. PLoS One. 2014; 9(9):e108772.
Lee SG, Lee YH (co-first), Kim KJ, Lee W, Kwon OH, Kim JH. Additive association of vitamin D insufficiency and sarcopenia with low femoral bone mineral density in noninstitutionalized elderly population: the Korea National Health and Nutrition Examination Surveys 2009-2010. Osteoporosis International 2013;24:2789-2799. [IF=4.169]
15. Lee YH (co-first), Han SJ, Kim HC, Hyung WJ, Lim JS, Lee K, Lee HJ, Lee EY, Kang ES, Ahn CW, Cha BS, Lee HC. Gastrectomy for early gastric cancer is associated with decreased cardiovascular mortality in association with postsurgical metabolic changes. Annals of Surgical Oncology 2013;20:1250-1257. [IF=4.120]
16. Lee YH (co-first), Kim SH, Lee YJ, Kang ES, Lee BW, Cha BS, Kim JW, DH Song, Lee HC. Transcription factor Snail is a novel regulator of adipocyte differentiation via inhibiting the expression of peroxisome proliferator-activated receptor gamma. Cellular and Molecular Life Sciences 2013;70:3959-3971. [IF=5.615]
9. Kim WD, Lee YH (co-first), Kim MH, Jung SY, Son WC, Yoon SJ, Lee BW. Human monoclonal antibodies against glucagon receptor improve glucose homeostasis by suppression of hepatic glucose output in diet-induced obese mice. PLoS One 2012;7:e50954.
10. Lee YH, Bang H, Kim HC, Kim HM, Park SW, Kim DJ. A simple screening score for diabetes for the Korean population: development, validation, and comparison with other scores. Diabetes Care 2012;35:1723-1730. [IF=11.857]
11. Lee YH, Lee BW, Kwon HJ, Kang ES, Cha BS, Lee HC. Higher morning to evening ratio in total dose of twice-daily biphasic insulin analog might be effective in achieving glucose control in patients with poorly controlled type 2 diabetes. Diabetes Technology & Therapeutics 2012;14:508-514.
12. Park YM, Lee YH (co-first), Kim SH, Lee EY, Kim KS, Williams DR, Lee HC. Snail, a transcriptional regulator, represses adiponectin expression by directly binding to an E-box motif in the promoter. Metabolism, clinical and experimental 2012;61:1622-1632. [IF=3.096]
13. Choe EY, Lee YH (co-first), Lee BW, Kang ES, Cha BS, Lee HC. Glycemic Effects of Once-a-Day Rapid-Acting Insulin Analogue Addition on a Basal Insulin Analogue in Korean Subjects with Poorly Controlled Type 2 Diabetes Mellitus. Diabetes and Metabolism Journal 2012;36:230-236. adiposity and may be an indicator of metabolic syndrome in male children and adolescents. Clinical endocrinology 2011;74:579-586.
7. Lee YH, Magkos F, Mantzoros CS, Kang ES. Effects of leptin and adiponectin on pancreatic β-cell function. Metabolism, clinical and experimental 2011;60:1664-1672. [IF=2.664]
8. Lee YH, Lee BW, Chun SW, Cha BS, Lee HC. Predictive characteristics of patients achieving glycaemic control with insulin after sulfonylurea failure. International Journal of Clinical Practice 2011;65:1076-1084.
4. Lee YH, Lee S, Jung ES, Kim J, Shim CY, Ko Y, Choi D, Jang Y, Chung N, Ha JW. Visceral adiposity and the severity of coronary artery disease in middle-aged subjects with normal waist circumference and its relation with lipocalin-2 and MCP-1. Atherosclerosis 2010;213:592-597.
5. Lee YH, Noh TW, Lee MK, Jameson JL, Lee EJ. Absence of activating mutations of CXCR4 in pituitary tumours. Clinical Endocrinology 2010;72:209-213.
6. Lee YH (co-first), Choi SH, Lee KW, Kim DJ. Apolipoprotein B/A1 ratio is associated with free androgen index and visceral
Lee YH (co-first), Kang ES, Kim SH, Han SJ, Kim CH, Kim HJ, Ahn CW, Cha BS, Nam M, Nam CM, Lee HC. Association between polymorphisms in SLC30A8, HHEX, CDKN2A/B, IGF2BP2, FTO, WFS1, CDKAL1, KCNQ1 and type 2 diabetes in the Korean population. Journal of Human Genetics 2008;53:991-998.
2. Lee YH (co-first), Kim JM, Lee EJ. Functional expression of CXCR4 in somatotrophs: CXCL12 activates GH gene, GH production and secretion, and cellular proliferation. Journal of Endocrinology 2008;199:191-199.
3. Lee YH (co-first), Kwon MK, Kang ES, Park YM, Choi SH, Ahn CW, Kim KS, Park CW, Cha BS, Kim SW, Sung JK, Lee EJ, Lee HC. Adenoviral vector-mediated glucagon-like peptide 1 gene therapy improves glucose homeostasis in Zucker diabetic fatty rats. Journal of Gene Medicine 2008;10:260-268.
1. Park CW, Park YM, Lee GT, Lee YH, Woo S, Cha JY, Ahn CW, Cha BS, Kim KS, Ahn Y, Lee HC. Targeting of therapeutic gene expression to the liver by using liver-type pyruvate kinase proximal promoter and the SV40 viral enhancer active in multiple cell types. Biochemical and Biophysical Research Communications 2004;314:131-7.
2. Park YM, Woo S, Lee GT, Ko JY, Lee YH, Zhao ZS, Kim HJ, Ahn CW, Cha BS, Kim KS, Park CW, Lee HC. Safety and efficacy of adeno-associated viral vector-mediated insulin gene transfer via portal vein to the livers of streptozotocin-induced diabetic Sprague-Dawley rats. Journal of Gene Medicine 2005;7:621-9.
3. Lee HJ, Lee YH, Park SK, Kang ES, Kim H, Lee YC, Choi CS, Park SE, Ahn CW, Cha BS, Lee KW, Kim KS, Lim SK, Lee HC. Korean red ginseng (Panax ginseng) improves insulin sensitivity and attenuates the development of diabetes in Otsuka Long-Evans Tokushima fatty rats. Metabolism, clinical and experimental 2009;58:1170-7. [IF=2.588]
4. Kim SH, Kim SH, Choi M, Lee YH, Kim YO, Ahn DS, Kim YH, Kang ES, Lee EJ, Jung M, Cho JW, Williams DR, Lee HC. Natural therapeutic magnesium lithospermate B potently protects the endothelium from hyperglycaemia-induced dysfunction. Cardiovascular Research 2010;87:713-22.
5. Hur KY, Kim SH, Choi M, Williams DR, Lee YH, Kang SW, Yadav UCS, Srivastav SK, Jung M, Cho JW, Kim SG, Kang ES, Lee EJ, Lee HC. Protective effects of magnesium lithospermate B against diabetic atherosclerosis via Nrf2-ARE-NQO1 transcriptional pathway. Atherosclerosis 2010;211:69-76.
6. Kim JM, Lee YH, Ku CR, Lee EJ. The cyclic pentapeptide d-Arg3FC131, a CXCR4 antagonist, induces apoptosis of somatotrope tumor and inhibits tumor growth in nude mice. Endocrinology 2011;152:536-44.
7. Lee BW, Chun SW, Kim SH, Lee YH, Kang ES, Cha BS, Lee HC. Lithospermic acid B protects beta-cells from cytokine-induced apoptosis by alleviating apoptotic pathways and activating anti-apoptotic pathways of Nrf2-HO-1 and Sirt1. Toxicology and Applied Pharmacology 2011; 252:47-54.
8. Lee EY, Lee B, Kim D, Lee YH, Kim KJ, Kang ES, Cha BS, Lee EJ, Lee HC. Glycated albumin is a useful glycation index for monitoring fluctuating and poorly controlled type 2 diabetic patients. Acta Diabetologica 2011;48:167-72.
9. Kim KJ, Kim KM, Park KH, Choi HS, Rhee Y, Lee YH, Cha BS, Kim MJ, Oh SM, Brown JK, Lim SK. Aortic calcification and bone metabolism: the relationship between aortic calcification, BMD, vertebral fracture, 25-hydroxyvitamin D, and osteocalcin. Calcified Tissue International 2012;91:370-8.
10. Lee SH, Lee HJ, Lee YH, Lee BW, Cha BS, Kang ES, Ahn CW, Park JS, Kim HJ, Lee EY, Lee HC. Korean red ginseng (Panax ginseng) improves insulin sensitivity in high fat fed Sprague-Dawley rats. Phytotherapy Research 2012; 26:142-7.
11. Lee CJ, Lee YH, Park SW, Kim KJ, Park S, Youn JC, Lee SH, Kang SM, Jang Y. Association of serum proprotein convertase subtilisin/kexin type 9 with carotid intima media thickness in hypertensive subjects. Metabolism, clinical and experimental 2013;62:845-50. [IF=3.611]
12. Hong N, Oh J, Lee YH, Youn JC, Park S, Lee SH, Jang Y, Chung N, Kim S, Jee SH, Kang SM. Comparison of association of glomerular filtration rate with metabolic syndrome in a community-based population using the CKD-EPI and MDRD study equations. Clinica Chimica Acta 2014;429:157-62.
13. Jung CH, Park JY, Cho JH, Yoon KH, Yang HK, Lee YH, Cha BS, Lee BW. The optimal morning:evening ratio in total dose of twice-daily biphasic insulin analogue in poorly controlled Type 2 diabetes: a 24-week multi-centre prospective, randomized controlled, open-labelled clinical study. Diabetic Medicine 2014;31:68-75.
14. Lee EY, Hwang S, Lee SH, Lee YH, Choi AR, Lee Y, Lee BW, Kang ES, Ahn CW, Cha BS, Lee HC. Postprandial C-peptide to glucose ratio as a predictor ofb-cell function and its usefulness for staged management of type 2 diabetes. Journal of Diabetes Investigation 2014;5:517-24.
15. Kim JE, Lee YH, Huh JH, Kang DR, Rhee Y, Lim SK. Early-stage chronic kidney disease, insulin resistance, and osteoporosis as risk factors of sarcopenia in aged population: The Fourth Korea National Health and Nutrition Examination Survey (KNHANES IV), 2008–2009. Osteoporosis International 2014;25:2189-98.
16. Choi SB, Kim WJ, Yoo TK, Park JS, Chung JW, Lee YH, Kang ES, Kim DW. Screening for pre-diabetes using machine learning models. Computational and Mathematical Methods in Medicine 2014;2014:618976.
17. Song YM, Lee YH, Kim JW, Ham DS, Kang ES, Cha BS, Lee HC, Lee BW. Metformin alleviates hepatosteatosis by restoring SIRT1-mediated autophagy induction via an AMP-activated protein kinase-independent pathway. Autophagy 2015;11:46-59.
18. Rim JH, Lee YH, Cha BS, Lee SG, Kim JH. Central obesity is an independent risk factor for microalbuminuria in both the general Korean women and nondiabetic nonhypertensive subpopulation: Association of microalbuminuria and metabolic syndrome from the KNHANES 2011-2012. Clinica Chimica Acta 2015;448:74-79.
19. Song BM, Kim HC, Lee JY, Lee JM, Kim DJ, Lee YH, Suh I. Performance of HbA1c for the prediction of diabetes in a rural community in Korea. Diabetic Medicine 2015;32:1602–1610.
20. Kim G, Jo K, Kim KJ, Lee YH, Han E, Yoon HJ, Wang HJ, Wang, HJ, Kang, ES, Yun, M. Visceral adiposity is associated with altered myocardial glucose uptake measured by (18)FDG-PET in 346 subjects with normal glucose tolerance, prediabetes, and type 2 diabetes. Cardiovascular Diabetology 2015;14:148.
21. Song YM, Lee WK, Lee YH, Kang ES, Cha BS, Lee BW. Metformin Restores Parkin-Mediated Mitophagy, Suppressed by Cytosolic p53. International Journal of Molecular Sciences 2016;17:122.
22. Han E, Jang SY, Kim G, Lee YH, Choe EY, Nam CM, Kang ES. Rosiglitazone Use and the Risk of Bladder Cancer in Patients With Type 2 Diabetes. Medicine (Baltimore). 2016;95:e2786.
23. Han E, Yun Y, Kim G, Lee YH, Wang HJ, Lee BW, Cha BS, Kim BS, Kang ES. Effects of Omega-3 Fatty Acid Supplementation on Diabetic Nephropathy Progression in Patients with Diabetes and Hypertriglyceridemia. PLoS One. 2016;11:e0154683.
24. Kim SR, Lee YH, Lee SG, Kang ES, Cha BS, Kim JH, Lee BW. Urinary N-acetyl-β-D-glucosaminidase, an early marker of diabetic kidney disease, might reflect glucose excursion in patients with type 2 diabetes. Medicine (Baltimore). 2016;95(27):e4114.
25. Park SH, Nam JY, Han E, Lee YH, Lee BW, Kim BS, Cha BS, Kim CS, Kang ES. Efficacy of different dipeptidyl peptidase-4 (DPP-4) inhibitors on metabolic parameters in patients with type 2 diabetes undergoing dialysis. Medicine (Baltimore). 2016;95(32):e4543.
26. Han E, Park HS, Kwon O, Choe EY, Wang HJ, Lee YH, Lee SH, Kim CH, Kim LK, Kwak SH, Park KS, Kim CS, Kang ES. A genetic variant in GLP1R is associated with response to DPP-4 inhibitors in patients with type 2 diabetes. Medicine (Baltimore). 2016;95(44):e5155.
27. Jeong B, Jung CH, Lee YH, Shin IH, Kim H, Bae SJ, Lee DS, Kang ES, Kang U, Kim JJ, Park JY. A novel imaging platform for non-invasive screening of abnormal glucose tolerance. Diabetes Res Clin Pract. 2016;116:83-5.
28. Park JS, Oh SY, Lee DH, Lee YS, Sung SH, Ji HW, Lee MJ, Lee YH, Rhee SG, Bae SH. p62/SQSTM1 is required for the protection against endoplasmic reticulum stress-induced apoptotic cell death. Free radical research. 2016;50(12):1408-1421.
29. Kang S, Lee YH, Lee JE. Metabolism-Centric Overview of the Pathogenesis of Alzheimer’s Disease. Yonsei Med J 2017;58(3):479-488.
30. Lee SW, Kim HC, Lee YH, Song BM, Choi H, Park JH, Rhee Y, Kim CO. Association between HbA1c and carotid atherosclerosis among elderly Koreans with normal fasting glucose. PLoS One. 2017;12(2):e0171761.
31. Kim SR, Lee YH, Lee SG, Kang ES, Cha BS, Lee BW. The renal tubular damage marker urinary N-acetyl-β-d-glucosaminidase may be more closely associated with early detection of atherosclerosis than the glomerular damage marker albuminuria in patients with type 2 diabetes. Cardiovasc Diabetol. 2017;16(1):16.
32. Lee DH, Park JS, Lee YS, Sung SH, Lee YH, Bae SH. The hypertension drug, verapamil activates Nrf2 by promoting p62-dependent autophagic Keap1 degradation and prevents acetaminophen-induced cytotoxicity. BMB Rep. 2017;50(2):91-96.
33. Lee EY, Hwang S, Lee YH, Lee SH, Lee YM, Kang HP, Han E, Lee W, Lee BW, Kang ES, Cha BS, Lee HC. Association between Metformin Use and Risk of Lactic Acidosis or Elevated Lactate Concentration in Type 2 Diabetes. Yonsei Med J. 2017;58(2):312-318.
34. Kim G, Jang SY, Han E, Lee YH, Park SY, Nam CM, Kang ES. Effect of statin on hepatocellular carcinoma in patients with type 2 diabetes: A nationwide nested case-control study. International Journal of Cancer. 2017;140(4):798-806.
35. Lee JY, Kim G, Kim SR, Lee YH, Lee BW, Cha BS, Kang ES. Clinical parameters affecting dapagliflozin response in patients with type 2 diabetes. Diabetes & Metabolism. 2017;43(2):191-194.
36. Yi SW, Park S, Lee YH, Park HJ, Balkau B, Yi JJ. Association between fasting glucose and all-cause mortality according to sex and age: a prospective cohort study. Scientific reports 2017;7(1):8194
37. Kwon SS, Lee SG, Lee YH, Lim JB, Kim JH. Homeostasis model assessment of insulin resistance in a general adult population in Korea: additive association of sarcopenia and obesity with insulin resistance. Clin Endocrinol (Oxf). 2017;86:44-51.
38. Han E, Kim G, Lee JY, Lee YH, Kim BS, Lee BW, Cha BS, Kang ES. Comparison between Atorvastatin and Rosuvastatin in Renal Function Decline among Patients with Diabetes. Endocrinology and metabolism. 2017;32(2):274-280.
39. Yi SW, Park S, Lee YH, Balkau B, Yi JJ. Fasting Glucose and All-Cause Mortality by Age in Diabetes: A Prospective Cohort Study. Diabetes Care. 2018;41:623–626. [IF=13.397]
40. Lee JY, Cho Y, Lee M, Lee YH, Lee BW, Kang ES, Cha BS. Clinical efficacy of the novel thiazolidinedione lobeglitazone in patients with type 2 diabetes. Diabetes & Metabolism 2018;44:449–455.
41. Yi SW, Choi JS, Yi JJ, Lee YH, Han KJ. Risk factors for hepatocellular carcinoma by age, sex, and liver disorder status: A prospective cohort study in Korea. Cancer. 2018;124(13):2748-2757.
42. Kim G, Lee YH, Yun MR, Lee JY, Shin EG, Lee BW, Kang ES, Cha BS. Effects of lobeglitazone, a novel thiazolidinedione, on adipose tissue remodeling and brown and beige adipose tissue development in db/db mice. International Journal of Obesity 2018;42:542–551. [IF=5.151]
43. Lee SG, Yim YS, Lee YH, Lee BW, Kim HS, Kim KS, Lee YW, Kim JH. Fasting serum amino acids concentration is associated with insulin resistance and pro-inflammatory cytokines. Diabetes Research and Clinical Practice 2018;140:107-117. [IF=2.548]
44. Lee M, Hong N, Lee YH, Kang ES, Cha BS, Lee BW. Elevated N-acetyl-beta-D-glucosaminidase, a urinary tubular damage marker, is a significant predictor of carotid artery atherosclerosis in type 1 diabetes, independent of albuminuria: A cross-sectional study. Journal of diabetes and its complications 2018;32(8):777-783. [IF=2.792]
45. Kim KH, Kim SH, Han DH, Jo YS, Lee YH, Lee MS. Growth differentiation factor 15 ameliorates nonalcoholic steatohepatitis and related metabolic disorders in mice. Scientific Reports 2018;8(1):6789. [IF=4.122]
46. Ko SH, Han K, Lee YH, Noh J, Park CY, Kim DJ, Jung CH, Lee KU, Ko KS; TaskForce Team for the Diabetes Fact Sheet of the Korean Diabetes Association. Past and Current Status of Adult Type 2 Diabetes Mellitus Management in Korea: A National Health Insurance Service Database Analysis. Diabetes & Metabolism Journal 2018;42(2):93-100. [IF=3.710]
47. Hong N, Lee M, Park S, Lee YH, Jin SM, Kim JH, Lee BW. Elevated urinary N-acetyl-β-D-glucosaminidase is associated with high glycoalbumin-to-hemoglobin A1c ratio in type 1 diabetes patients with early diabetic kidney disease. Scientific Reports 2018;8(1):6710. [IF=4.122]
48. Kim JJ, Jeong B, Cho Y, Kwon MH, Lee YH, Kang U, Kang ES. The association between skin auto-fluorescence of palmoplantar sites and microvascular complications in Asian patients with type 2 diabetes mellitus. Scientific Reports 2018;8(1):6309. [IF=4.122]
49. Hur KY, Jun JE, Choi YJ, Lee YH, Kim DJ, Park SW, Huh BW, Lee EJ, Jee SH, Huh KB, Choi SH. Color Doppler Ultrasonography Is a Useful Tool for Diagnosis of Peripheral Artery Disease in Type 2 Diabetes Mellitus Patients with Ankle-Brachial Index 0.91 to 1.40. Diabetes & Metabolism Journal 2018;42(1):63-73. [IF=3.710]
50. Jun JE, Choi YJ, Lee YH, Kim DJ, Park SW, Huh BW, Lee EJ, Jee SH, Hur KY, Choi SH, Huh KB. ApoB/ApoA-I ratio is independently associated with carotid atherosclerosis in type 2 diabetes mellitus with well-controlled LDL cholesterol levels. Korean journal of internal medicine 2018;33(1):138-147. [IF=2.131]
51. Ko SH, Park YM, Yun JS, Cha SA, Choi EK, Han K, Han E, Lee YH, Ahn YB. Severe Hypoglycemia is a Risk Factor for Atrial Fibrillation in Type 2 Diabetes Mellitus: Nationwide Population-Based Cohort Study. Journal of Diabetes and Its Complications 2018;32(2):157-163. [IF=2.792]
52. Moon SW, Kim SY, Jung JY, Kang YA, Park MS, Kim YS, Chang J, Ro JS, Lee YH, Lee SH. The relationship between obstructive lung disease and non-alcoholic fatty liver disease in the Korean population: Korea national health and nutrition examination survey, 2007–2010. International Journal of Chronic Obstructive Pulmonary Disease. 2018:13 2603–2611 [IF=2.917]
53. Cho YY, Kang MJ, Kim SK, Jung JH, Hahm JR, Kim TH, Nam JY, Lee BW, Lee YH, Chung JH, Song SO, Kim SW. Protective Effect of Metformin Against Thyroid Cancer Development: A Population-Based Study in Korea. Thyroid. 2018 Jul;28(7):864-870.
54. Lee CJ, Hwang J, Lee YH, Oh J, Lee SH, Kang SM, Choi D, Kim HC, Park S. Blood pressure level associated with lowest cardiovascular event in hypertensive diabetic patients. Journal of Hypertension. 2018 Dec;36(12):2434-2443.
55. Ha KH, Lee YH, Song SO, Lee JW, Kim DW, Cho KH, Kim DJ. Development and Validation of the Korean Diabetes Risk Score: A 10-Year National Cohort Study. Diabetes & Metabolism Journal. 2018 Oct;42(5):402-414.
56. Kim NH, Lim S, Kwak SH, Moon MK, Moon JS, Lee YH, Cho HC, Lee J, Kim SG. Efficacy and tolerability of novel triple combination therapy in drug-naïve patients with type 2 diabetes from the TRIPLE-AXEL trial: protocol for an open-label randomised controlled trial. BMJ Open. 2018 Sep 24;8(9):e022448.
57. Lee G, Ma Y, Lee YH, Jung H. Clinical Evaluation of a Low-pain Long Microneedle for Subcutaneous Insulin Injection. BioChip J 2018;12(4):309-316.
58. Lee JY, Kim G, Lee YH, Lee BW, Cha BS, Nam CM, Kang ES. Comparison of hepatocellular carcinoma risk between patients treated with glimepiride and gliclazide. Diabetes & Metabolism 2019;45:83–85.
59. Han E, Kim MK, Lee YH, Kim HS, Lee BW. Association between nonalbumin proteinuria and renal tubular damage of N-acetyl-β-D-glucosaminidase and its clinical relevance in patients with type 2 diabetes without albuminuria. Journal of Diabetes and Its Complications. 2019;33:255–260.
60. Lee SG, Lee YH, Choi E, Cho Y, Kim JH. Fasting serum bile acids concentration is associated with insulin resistance independently of diabetes status. Clin Chem Lab Med 2019 https://doi.org/10.1515/cclm-2018-0741
61. Lee JY, Cho Y, Lee M, Kim YJ, Lee YH, Lee BW, Cha BS, Kang ES. Predictors of the Therapeutic Efficacy and Consideration of the Best Combination Therapy of Sodium-Glucose Co-transporter 2 Inhibitors. Diabetes & Metabolism Journal. 2019 https://doi.org/10.4093/dmj.2018.0057
62. Han E, Shin E, Kim G, Lee J-Y, Lee YH, Lee B-W, Kang ES and Cha BS. Combining SGLT2 Inhibition With a Thiazolidinedione Additively Attenuate the Very Early Phase of Diabetic Nephropathy Progression in Type 2 Diabetes Mellitus. Front. Endocrinol. 2018;9:412.
63. Bae JH, Kim Y, Cho Y, Lee M, Lee JY, Lee YH, Lee BW, Cha BS, Joo DJ, Huh KH, Kim MS, Kim YS, Kang ES. Efficacy and Safety of Gemigliptin in Post-Transplant Patients With Type 2 Diabetes Mellitus. Transplantation Proceedings, 51, 3444-3448 (2019).
64. Cho Y, Hong NK, Kim K, Cho SJ, Lee M, Lee Y, Lee YH, Kang ES, Cha BS, Lee BW. The Effectiveness of Intermittent Fasting to Reduce Body Mass Index and Glucose Metabolism: A Systematic Review and Meta-Analysis. Journal of Clinical Medicine 2019, 8, 1645.
65. Bae JH, Lee YH, Kang ES, Cha BS, Lee BW. Proteinuria Is Associated with Carotid Artery Atherosclerosis in Non-Albuminuric Type 2 Diabetes: A Cross-Sectional Study. Journal of Clinical Medicine 2020, 9, 136.
66. Cho Y, Lee YH, Kang ES, Cha BS, Lee BW. Glucometabolic characteristics and higher vascular complication risk in Korean patients with type 2 diabetes with non-albumin proteinuria. Journal of Diabetes and Its Complications 33 (2019) 585–591.
67. Seo DH, Kang S, Lee YH, Ha JY, Park JS, Lee BW, Kang ES, Ahn CW, Cha BS. Current Management of Type 2 Diabetes Mellitus in Primary Care Clinics in Korea. Endocrinol Metab 2019;34:282-290.
68. Bae J, Kim G, Lee YH, Lee BW, Kang ES, Cha BS. Differential Effects of Thiazolidinediones and Dipeptidyl Peptidase-4 Inhibitors on Insulin Resistance and b-Cell Function in Type 2 Diabetes Mellitus: A Propensity Score-Matched Analysis. Diabetes Ther (2019) 10:149–158.
69. Seok H, Lee M, Shin E, Yun MR, Lee YH, Moon JH, Kim E, Lee PH, Lee BW, Kang ES, Lee HC, Cha BS. Low-dose pioglitazone can ameliorate learning and memory impairment in a mouse model of dementia by increasing LRP1 expression in the hippocampus. Scientific reports 2019;9:4414.
70. Seo DH, Lee YH, Park SW, Choi YJ, Huh BW, Lee EJ, Huh KB, Kim SH, Cha BS. Sarcopenia is associated with non-alcoholic fatty liver disease in men with type 2 diabetes. Diabetes & Metabolism 2020;46(5):362-369.
71. Jun JE, …, Lee YH, … Lee MK. Efficacy and Safety of Omega-3 Fatty Acids in Patients Treated with Statins for Residual Hypertriglyceridemia: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial. Diabetes Metab J 2020;44:78-90.
72. Kim E, Kang JG, Kang MJ, Park JH, Kim YJ, Kweon TH, Lee HW, Jho EH, Lee YH, Kim SI, Yi EC, Park HW, Yang WH, Cho JW.O-GlcNAcylation on LATS2 disrupts the Hippo pathway by inhibiting its activity. Proc Natl Acad Sci U S A. 2020 Jun 23;117(25):14259-14269.
73. Lee DH, Park JS, Lee YS, Han J, Lee DK, Kwon SW, Han DH, Lee YH, Bae SH. SQSTM1/p62 activates NFE2L2/NRF2 via ULK1-mediated autophagic KEAP1 degradation and protects mouse liver from lipotoxicity. Autophagy. 2020 Jan 10;1-25.
74. Lee SG, Lee SJ, Lee JJ, Kim JS, Lee OH, Kim CK, Kim D, Lee YH, Oh J, Park S, Jeon OH, Hong SJ, Ahn CM, Kim BK, Ko YG, Choi D, Hong MK, Jang Y. Anti-Inflammatory Effect for Atherosclerosis Progression by Sodium-Glucose Cotransporter 2 (SGLT-2) Inhibitor in a Normoglycemic Rabbit Model . Korean Circ J. 2020 May;50(5):443-457.
75. Lee BW, Lee YH, Park CY, Rhee EJ, Lee WY, Kim NH, Choi KM, Park KG, Choi YK, Cha BS, Lee DH. Non-Alcoholic Fatty Liver Disease in Patients with Type 2 Diabetes Mellitus: A Position Statement of the Fatty Liver Research Group of the Korean Diabetes Association. Diabetes Metab J 2020;44:382-401.
76. Ferrannini E, Murthy AC, Lee YH, Muscelli E, Weiss S, Ostroff RM, Sattar N, Williams SA, Ganz P. Mechanisms of Sodium–Glucose Cotransporter 2 Inhibition: Insights From Large-Scale Proteomics. Diabetes Care 2020;43(9):2183-9.
77. Dongwoo Kim 1, Hae Young Ko 1, Sangwon Lee 1, Yong-Ho Lee 2, Sujin Ryu 3, Seon Yoo Kim 1, Jee-In Chung 1, Misu Lee 4, Ju Hyung Moon 5, Jong Hee Chang 5, Mijin Yun. Glucose loading enhances the value of 18F-FDG PET/CT for the characterization and delineation of cerebral gliomas. Cancers (Basel). 2020 Jul 20;12(7):1977.
78. Da Hea Seo 1, Yong-Ho Lee 2, Young Ju Suh 3, Seong Hee Ahn 1, Seongbin Hong 1, Young Ju Choi 4, Byoung Wook Huh 4, Seok Won Park 2, Eunjig Lee 2, So Hun Kim. Low muscle mass is associated with carotid atherosclerosis in patients with type 2 diabetes. Atherosclerosis. 2020 Jul;305:19-25.
79. Jin Ha Lee 1, Ji Young Oh 2, Soo Hyun Kim 2, In Jeong Oh 2, Yong-Ho Lee 2, Keun Woo Lee 1, Woong Hee Lee 1 3, Jeong-Hwan Kim Pharmaceutical efficacy of gypenoside lxxv on non‐alcoholic steatohepatitis. Biomolecules. 2020 Oct 8;10(10):1426.
80. Ji Hong You 1 2, Sun Ok Song 1, Min Jin Kang 3, Yoon Young Cho 4, Sun Wook Kim 5, Sung Hwan Suh 6, Sujin Lee 7, Yong-Ho Lee 8, Byung-Wan Lee 8 Metformin and Gastrointestinal Cancer Development in Newly Diagnosed Type 2 Diabetes: A Population-Based Study in Korea. Clin Transl Gastroenterol. 2020 Nov;11(11):e00254.
81. Eugene Han 1, Yongin Cho 2, Kyung-Won Kim 2, Yong-Ho Lee 2, Eun Seok Kang 2, Bong-Soo Cha 2, Byung-Wan Lee. Hepatic fibrosis is associated with total proteinuria in Korean patients with type 2 diabetes. Medicine (Baltimore). 2020 Aug 14;99(33):e21038.
82. Eugene Han 1, Minyoung Lee 2, Yong-Ho Lee 2 3 4, Hye Soon Kim 1, Byung-Wan Lee 2 3 4, Bong-Soo Cha 2 3 4, Eun Seok Kang Effect of Switching from Linagliptin to Teneligliptin Dipeptidyl Peptidase-4 Inhibitors in Older Patients with Type 2 Diabetes Mellitus. Diabetes Metab Syndr Obes. 2020 Nov 2;13:4113-4121.
83. Minyoung Lee 1, Eugene Shin 2, Jaehyun Bae 1, Yongin Cho 3, Ji-Yeon Lee 1, Yong-Ho Lee 1, Byung-Wan Lee 1, Eun Seok Kang 1, Bong-Soo Cha. Dipeptidyl peptidase-4 inhibitor protects against non-alcoholic steatohepatitis in mice by targeting TRAIL receptor-mediated lipoapoptosis via modulating hepatic dipeptidyl peptidase-4 expression. Sci Rep. 2020 Nov 10;10(1):19429.
84.
Klionsky DJ, et al, Lee YH, Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition). Autophagy, 2021;17:1-382
Junghwa Seo 1 2, Yun Soo Park 1 2, Tae Hyun Kweon 1 2, Jingu Kang 1 2, Seongjin Son 1 2, Han Byeol Kim 3, Yu Ri Seo 3, Min Jueng Kang 3, Eugene C Yi 1 3, Yong-Ho Lee 1 4, Jin-Hong Kim 1 5, Boyoun Park 1 6, Won Ho Yang 1 6, Jin Won Cho O-Linked N-Acetylglucosamine Modification of Mitochondrial Antiviral Signaling Protein Regulates Antiviral Signaling by Modulating Its Activity. Front Immunol. 2021 Feb 2;11:589259
Minyoung Lee 1, Kwang Joon Kim 1, Tae-Ha Chung 2, Jaehyun Bae 1, Yong-Ho Lee 1 3, Byung-Wan Lee 1 3, Bong-Soo Cha 1 3, Mijin Yun 4, Eun Seok Kang Nonalcoholic fatty liver disease, diastolic dysfunction, and impaired myocardial glucose uptake in patients with type 2 diabetes Diabetes Obes Metab. 2021 Apr;23(4):1041-1051
Jaehyun Bae 1, Ji Hye Huh 2 3, Minyoung Lee 4, Yong-Ho Lee 4, Byung-Wan Lee Glycaemic control with add-on thiazolidinedione or a sodium-glucose co-transporter-2 inhibitor in patients with type 2 diabetes after the failure of an oral triple antidiabetic regimen: A 24-week, randomized controlled trial. Diabetes Obes Metab. 2021 Feb;23(2):609-618.